-
1
-
-
59949091427
-
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome
-
10.1101/gr.080259.108, 2652200, 19056696
-
Hampton OA, Den Hollander P, Miller CA, Delgado DA, Li J, Coarfa C, Harris RA, Richards S, Scherer SE, Muzny DM, Gibbs RA, Lee AV, Milosavljevic A. A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome. Genome Res 2009, 19:167-77. 10.1101/gr.080259.108, 2652200, 19056696.
-
(2009)
Genome Res
, vol.19
, pp. 167-177
-
-
Hampton, O.A.1
Den Hollander, P.2
Miller, C.A.3
Delgado, D.A.4
Li, J.5
Coarfa, C.6
Harris, R.A.7
Richards, S.8
Scherer, S.E.9
Muzny, D.M.10
Gibbs, R.A.11
Lee, A.V.12
Milosavljevic, A.13
-
2
-
-
33748669269
-
High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation
-
10.1038/sj.onc.1209570, 16636668
-
Pole JC, Courtay-Cahen C, Garcia MJ, Blood KA, Cooke SL, Alsop AE, Tse DM, Caldas C, Edwards PA. High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation. Oncogene 2006, 25:5693-706. 10.1038/sj.onc.1209570, 16636668.
-
(2006)
Oncogene
, vol.25
, pp. 5693-5706
-
-
Pole, J.C.1
Courtay-Cahen, C.2
Garcia, M.J.3
Blood, K.A.4
Cooke, S.L.5
Alsop, A.E.6
Tse, D.M.7
Caldas, C.8
Edwards, P.A.9
-
3
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
10.1038/nature05610, 2712719, 17344846
-
Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, et al. Patterns of somatic mutation in human cancer genomes. Nature 2007, 446:153-8. 10.1038/nature05610, 2712719, 17344846.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
Dalgliesh, G.L.4
Hunter, C.5
Bignell, G.6
Davies, H.7
Teague, J.8
Butler, A.9
Stevens, C.10
Edkins, S.11
O'Meara, S.12
Vastrik, I.13
Schmidt, E.E.14
Avis, T.15
Barthorpe, S.16
Bhamra, G.17
Buck, G.18
Choudhury, B.19
Clements, J.20
Cole, J.21
Dicks, E.22
Forbes, S.23
Gray, K.24
Halliday, K.25
Harrison, R.26
Hills, K.27
Hinton, J.28
Jenkinson, A.29
Jones, D.30
more..
-
4
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
10.1126/science.1164368, 2848990, 18772397
-
Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Jimeno A, Hong SM, Fu B, Lin MT, Calhoun ES, Kamiyama M, Walter K, Nikolskaya T, Nikolsky Y, Hartigan J, Smith DR, Hidalgo M, Leach SD, Klein AP, Jaffee EM, Goggins M, Maitra A, Iacobuzio-Donahue C, Eshleman JR, Kern SE, Hruban RH, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008, 321:1801-6. 10.1126/science.1164368, 2848990, 18772397.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
Zhang, X.2
Parsons, D.W.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Kamiyama, H.9
Jimeno, A.10
Hong, S.M.11
Fu, B.12
Lin, M.T.13
Calhoun, E.S.14
Kamiyama, M.15
Walter, K.16
Nikolskaya, T.17
Nikolsky, Y.18
Hartigan, J.19
Smith, D.R.20
Hidalgo, M.21
Leach, S.D.22
Klein, A.P.23
Jaffee, E.M.24
Goggins, M.25
Maitra, A.26
Iacobuzio-Donahue, C.27
Eshleman, J.R.28
Kern, S.E.29
Hruban, R.H.30
Karchin, R.31
Papadopoulos, N.32
Parmigiani, G.33
Vogelstein, B.34
Velculescu, V.E.35
Kinzler, K.W.36
more..
-
5
-
-
43049173659
-
High-resolution genomic and expression analyses of copy number alterations in breast tumors
-
10.1002/gcc.20558, 18335499
-
Haverty PM, Fridlyand J, Li L, Getz G, Beroukhim R, Lohr S, Wu TD, Cavet G, Zhang Z, Chant J. High-resolution genomic and expression analyses of copy number alterations in breast tumors. Genes Chromosomes Cancer 2008, 47:530-42. 10.1002/gcc.20558, 18335499.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 530-542
-
-
Haverty, P.M.1
Fridlyand, J.2
Li, L.3
Getz, G.4
Beroukhim, R.5
Lohr, S.6
Wu, T.D.7
Cavet, G.8
Zhang, Z.9
Chant, J.10
-
6
-
-
38049100456
-
Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
-
10.1073/pnas.0710052104, 2148413, 18077431
-
Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, Vivanco I, Lee JC, Huang JH, Alexander S, Du J, Kau T, Thomas RK, Shah K, Soto H, Perner S, Prensner J, Debiasi RM, Demichelis F, Hatton C, Rubin MA, Garraway LA, Nelson SF, Liau L, Mischel PS, Cloughesy TF, Meyerson M, Golub TA, Lander ES, Mellinghoff IK, Sellers WR. Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma. PNAS 2007, 104:20007-20012. 10.1073/pnas.0710052104, 2148413, 18077431.
-
(2007)
PNAS
, vol.104
, pp. 20007-20012
-
-
Beroukhim, R.1
Getz, G.2
Nghiemphu, L.3
Barretina, J.4
Hsueh, T.5
Linhart, D.6
Vivanco, I.7
Lee, J.C.8
Huang, J.H.9
Alexander, S.10
Du, J.11
Kau, T.12
Thomas, R.K.13
Shah, K.14
Soto, H.15
Perner, S.16
Prensner, J.17
Debiasi, R.M.18
Demichelis, F.19
Hatton, C.20
Rubin, M.A.21
Garraway, L.A.22
Nelson, S.F.23
Liau, L.24
Mischel, P.S.25
Cloughesy, T.F.26
Meyerson, M.27
Golub, T.A.28
Lander, E.S.29
Mellinghoff, I.K.30
Sellers, W.R.31
more..
-
7
-
-
62549112118
-
Basic principles and technologies for deciphering the genetic map of cancer
-
10.1007/s00268-008-9851-y, 19115029
-
Voidonikolas G, Kreml SS, Chen C, Fisher WE, Brunicardi FC, Gibbs RA, Gingras MC. Basic principles and technologies for deciphering the genetic map of cancer. World J Surg 2009, 33:615-29. 10.1007/s00268-008-9851-y, 19115029.
-
(2009)
World J Surg
, vol.33
, pp. 615-629
-
-
Voidonikolas, G.1
Kreml, S.S.2
Chen, C.3
Fisher, W.E.4
Brunicardi, F.C.5
Gibbs, R.A.6
Gingras, M.C.7
-
8
-
-
6344222248
-
Human, Mouse and Rat Genome Large Scale Rearrangements: Stability Versus Speciation
-
10.1101/gr.2663304, 524408, 15364903
-
Zhao S, Shetty J, Hou L, Delcher A, Zhu B, Osoegawa K, de Jong P, Nierman WC, Strausberg RL, Fraser CM. Human, Mouse and Rat Genome Large Scale Rearrangements: Stability Versus Speciation. Genome Res 2004, 14:1851-60. 10.1101/gr.2663304, 524408, 15364903.
-
(2004)
Genome Res
, vol.14
, pp. 1851-1860
-
-
Zhao, S.1
Shetty, J.2
Hou, L.3
Delcher, A.4
Zhu, B.5
Osoegawa, K.6
de Jong, P.7
Nierman, W.C.8
Strausberg, R.L.9
Fraser, C.M.10
-
9
-
-
0038271921
-
Human and mouse genomic sequences reveal extensive breakpoint reuse in mammalian evolution
-
10.1073/pnas.1330369100, 164646, 12810957
-
Pevzner P, Tesler G. Human and mouse genomic sequences reveal extensive breakpoint reuse in mammalian evolution. PNAS 2003, 100:7672-7. 10.1073/pnas.1330369100, 164646, 12810957.
-
(2003)
PNAS
, vol.100
, pp. 7672-7677
-
-
Pevzner, P.1
Tesler, G.2
-
10
-
-
0029143510
-
ApcMin: a mouse model for intestinal and mammary tumorigenesis
-
10.1016/0959-8049(95)00181-H, 7576992
-
Moser AR, Luongo C, Gould KA, McNeley MK, Shoemaker AR, Dove WF. ApcMin: a mouse model for intestinal and mammary tumorigenesis. Eur J Cancer 1995, 31A:1061-4. 10.1016/0959-8049(95)00181-H, 7576992.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 1061-1064
-
-
Moser, A.R.1
Luongo, C.2
Gould, K.A.3
McNeley, M.K.4
Shoemaker, A.R.5
Dove, W.F.6
-
11
-
-
0027340690
-
ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias
-
10.1073/pnas.90.19.8977, 47484, 8415640
-
Moser AR, Mattes EM, Dove WF, Lindstrom MJ, Haag JD, Gould MN. ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias. PNAS 1993, 90:8977-81. 10.1073/pnas.90.19.8977, 47484, 8415640.
-
(1993)
PNAS
, vol.90
, pp. 8977-8981
-
-
Moser, A.R.1
Mattes, E.M.2
Dove, W.F.3
Lindstrom, M.J.4
Haag, J.D.5
Gould, M.N.6
-
12
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
10.1016/S0092-8674(00)81333-1, 8861899
-
Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996, 87:159-170. 10.1016/S0092-8674(00)81333-1, 8861899.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
13
-
-
0141576687
-
The significance of unstable chromosomes in colorectal cancer
-
10.1038/nrc1165, 12951588
-
Rajagopalan H, Nowak MA, Vogelstein B, Lengauer C. The significance of unstable chromosomes in colorectal cancer. Nat Rev Cancer 2003, 3:695-701. 10.1038/nrc1165, 12951588.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 695-701
-
-
Rajagopalan, H.1
Nowak, M.A.2
Vogelstein, B.3
Lengauer, C.4
-
14
-
-
33751082666
-
Stage-specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesis
-
10.1002/gcc.20382, 17044061
-
Habermann JK, Paulsen U, Roblick UJ, Upender MB, McShane LM, Korn EL, Wangsa D, Krüger S, Duchrow M, Bruch HP, Auer G, Ried T. Stage-specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesis. Genes Chromosomes Cancer 2007, 46:10-26. 10.1002/gcc.20382, 17044061.
-
(2007)
Genes Chromosomes Cancer
, vol.46
, pp. 10-26
-
-
Habermann, J.K.1
Paulsen, U.2
Roblick, U.J.3
Upender, M.B.4
McShane, L.M.5
Korn, E.L.6
Wangsa, D.7
Krüger, S.8
Duchrow, M.9
Bruch, H.P.10
Auer, G.11
Ried, T.12
-
15
-
-
40449141527
-
Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome
-
10.1158/0008-5472.CAN-07-2864, 18316590
-
Camps J, Grade M, Nguyen QT, Hörmann P, Becker S, Hummon AB, Rodriguez V, Chandrasekharappa S, Chen Y, Difilippantonio MJ, Becker H, Ghadimi BM, Ried T. Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome. Cancer Res 2008, 68:1284-95. 10.1158/0008-5472.CAN-07-2864, 18316590.
-
(2008)
Cancer Res
, vol.68
, pp. 1284-1295
-
-
Camps, J.1
Grade, M.2
Nguyen, Q.T.3
Hörmann, P.4
Becker, S.5
Hummon, A.B.6
Rodriguez, V.7
Chandrasekharappa, S.8
Chen, Y.9
Difilippantonio, M.J.10
Becker, H.11
Ghadimi, B.M.12
Ried, T.13
-
16
-
-
33644860129
-
Genome-wide differences between microsatellite stable and unstable colorectal tumors
-
10.1093/carcin/bgi244, 16272173
-
Camps J, Armengol G, del Rey J, Lozano JJ, Vauhkonen H, Prat E, Egozcue J, Sumoy L, Knuutila S, Miró R. Genome-wide differences between microsatellite stable and unstable colorectal tumors. Carcinogenesis 2006, 27:419-2. 10.1093/carcin/bgi244, 16272173.
-
(2006)
Carcinogenesis
, vol.27
, pp. 419-422
-
-
Camps, J.1
Armengol, G.2
del Rey, J.3
Lozano, J.J.4
Vauhkonen, H.5
Prat, E.6
Egozcue, J.7
Sumoy, L.8
Knuutila, S.9
Miró, R.10
-
17
-
-
0031841276
-
DNA mismatch repair and colorectal cancer
-
10.1002/(SICI)1096-9896(199806)185:2<123::AID-PATH62>3.0.CO;2-P, 9713337
-
Toft NJ, Arends MJ. DNA mismatch repair and colorectal cancer. J Pathol 1998, 185:123-129. 10.1002/(SICI)1096-9896(199806)185:2<123::AID-PATH62>3.0.CO;2-P, 9713337.
-
(1998)
J Pathol
, vol.185
, pp. 123-129
-
-
Toft, N.J.1
Arends, M.J.2
-
18
-
-
39149124108
-
DA and Xiao-two giant and composite LTR-retrotransposon-like elements identified in the human genome
-
10.1016/j.ygeno.2007.10.014, 18083327
-
Ji X, Zhao S. DA and Xiao-two giant and composite LTR-retrotransposon-like elements identified in the human genome. Genomics 2008, 91:249-58. 10.1016/j.ygeno.2007.10.014, 18083327.
-
(2008)
Genomics
, vol.91
, pp. 249-258
-
-
Ji, X.1
Zhao, S.2
-
19
-
-
2942625830
-
Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus
-
10.1016/j.ygeno.2004.01.015, 15203215
-
Askew DJ, Askew YS, Kato Y, Turner RF, Dewar K, Lehoczky J, Silverman GA. Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus. Genomics 2004, 84:176-84. 10.1016/j.ygeno.2004.01.015, 15203215.
-
(2004)
Genomics
, vol.84
, pp. 176-184
-
-
Askew, D.J.1
Askew, Y.S.2
Kato, Y.3
Turner, R.F.4
Dewar, K.5
Lehoczky, J.6
Silverman, G.A.7
-
20
-
-
0036796354
-
Mammalian retroelements
-
10.1101/gr.282402, 12368238
-
Deininger PL, Batzer MA. Mammalian retroelements. Genome Res 2002, 12:1455-65. 10.1101/gr.282402, 12368238.
-
(2002)
Genome Res
, vol.12
, pp. 1455-1465
-
-
Deininger, P.L.1
Batzer, M.A.2
-
21
-
-
0035895505
-
The Sequence of the Human Genome
-
10.1126/science.1058040, 11181995
-
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, et al. The Sequence of the Human Genome. Science 2001, 291:1304-1351. 10.1126/science.1058040, 11181995.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
Yandell, M.8
Evans, C.A.9
Holt, R.A.10
Gocayne, J.D.11
Amanatides, P.12
Ballew, R.M.13
Huson, D.H.14
Wortman, J.R.15
Zhang, Q.16
Kodira, C.D.17
Zheng, X.H.18
Chen, L.19
Skupski, M.20
Subramanian, G.21
Thomas, P.D.22
Zhang, J.23
Gabor Miklos, G.L.24
Nelson, C.25
Broder, S.26
Clark, A.G.27
Nadeau, J.28
McKusick, V.A.29
Zinder, N.30
more..
-
22
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
10.1038/35057062, 11237011, International Human Genome Sequencing Consortium
-
International Human Genome Sequencing Consortium Initial sequencing and analysis of the human genome. Nature 2001, 409:860-921. 10.1038/35057062, 11237011, International Human Genome Sequencing Consortium.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
-
23
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
10.1016/S0092-8674(03)00432-X, 12809600
-
Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003, 113:685-700. 10.1016/S0092-8674(03)00432-X, 12809600.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
24
-
-
0034644472
-
TGFbeta signaling in growth control, cancer, and heritable disorders
-
10.1016/S0092-8674(00)00121-5, 11057902
-
Massague J, Blain SW, Lo RS. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 2000, 103:295-309. 10.1016/S0092-8674(00)00121-5, 11057902.
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massague, J.1
Blain, S.W.2
Lo, R.S.3
-
25
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
10.1126/science.271.5247.350, 8553070
-
Hahn SA, Schutte M, Hoque AT, Moskaluk CA, da Costa LT, Rozenblum E, Weinstein CL, Fischer A, Yeo CJ, Hruban RH, Kern SE. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996, 271:350-3. 10.1126/science.271.5247.350, 8553070.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
26
-
-
15844390729
-
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
-
10.1038/ng0796-343, 8673134
-
Thiagalingam S, Lengauer C, Leach FS, Schutte M, Hahn SA, Overhauser J, Willson JK, Markowitz S, Hamilton SR, Kern SE, Kinzler KW, Vogelstein B. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nat Genet 1996, 13:343-6. 10.1038/ng0796-343, 8673134.
-
(1996)
Nat Genet
, vol.13
, pp. 343-346
-
-
Thiagalingam, S.1
Lengauer, C.2
Leach, F.S.3
Schutte, M.4
Hahn, S.A.5
Overhauser, J.6
Willson, J.K.7
Markowitz, S.8
Hamilton, S.R.9
Kern, S.E.10
Kinzler, K.W.11
Vogelstein, B.12
-
27
-
-
0030848192
-
Frequency of Smad gene mutations in human cancers
-
Riggins GJ, Kinzler KW, Vogelstein B, Thiagalingam S. Frequency of Smad gene mutations in human cancers. Cancer Res 1997, 57:2578-80.
-
(1997)
Cancer Res
, vol.57
, pp. 2578-2580
-
-
Riggins, G.J.1
Kinzler, K.W.2
Vogelstein, B.3
Thiagalingam, S.4
-
28
-
-
0033572255
-
Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice
-
Takaku K, Miyoshi H, Matsunaga A, Oshima M, Sasaki N, Taketo MM. Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice. Cancer Res 1999, 59:6113-7.
-
(1999)
Cancer Res
, vol.59
, pp. 6113-6117
-
-
Takaku, K.1
Miyoshi, H.2
Matsunaga, A.3
Oshima, M.4
Sasaki, N.5
Taketo, M.M.6
-
29
-
-
0032489508
-
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
-
10.1016/S0092-8674(00)81132-0, 9506519
-
Takaku K, Oshima M, Miyoshi H, Matsui M, Seldin MF, Taketo MM. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 1998, 92:645-56. 10.1016/S0092-8674(00)81132-0, 9506519.
-
(1998)
Cell
, vol.92
, pp. 645-656
-
-
Takaku, K.1
Oshima, M.2
Miyoshi, H.3
Matsui, M.4
Seldin, M.F.5
Taketo, M.M.6
-
30
-
-
0025056930
-
Identification of a chromosome 18q gene that is altered in colorectal cancers
-
10.1126/science.2294591, 2294591
-
Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert JM, Hamilton SR, Preisinger AC, Thomas G, Kinzler KW, Vogelstein B. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 1990, 247:49-56. 10.1126/science.2294591, 2294591.
-
(1990)
Science
, vol.247
, pp. 49-56
-
-
Fearon, E.R.1
Cho, K.R.2
Nigro, J.M.3
Kern, S.E.4
Simons, J.W.5
Ruppert, J.M.6
Hamilton, S.R.7
Preisinger, A.C.8
Thomas, G.9
Kinzler, K.W.10
Vogelstein, B.11
-
31
-
-
0030995125
-
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene
-
Fazeli A, Dickinson SL, Hermiston ML, Tighe RV, Steen RG, Small CG, Stoeckli ET, Keino-Masu K, Masu M, Rayburn H, Simons J, Bronson RT, Gordon JI, Tessier-Lavigne M, Weinberg RA. Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature 1999, 386:796-804.
-
(1999)
Nature
, vol.386
, pp. 796-804
-
-
Fazeli, A.1
Dickinson, S.L.2
Hermiston, M.L.3
Tighe, R.V.4
Steen, R.G.5
Small, C.G.6
Stoeckli, E.T.7
Keino-Masu, K.8
Masu, M.9
Rayburn, H.10
Simons, J.11
Bronson, R.T.12
Gordon, J.I.13
Tessier-Lavigne, M.14
Weinberg, R.A.15
-
32
-
-
31544438541
-
Aneuploidy-dependent massive deregulation of the cellular transcriptome and apparent divergence of the Wnt/beta-catenin signaling pathway in human rectal carcinomas
-
10.1158/0008-5472.CAN-05-2533, 16397240
-
Grade M, Ghadimi BM, Varma S, Simon R, Wangsa D, Barenboim-Stapleton L, Liersch T, Becker H, Ried T, Difilippantonio MJ. Aneuploidy-dependent massive deregulation of the cellular transcriptome and apparent divergence of the Wnt/beta-catenin signaling pathway in human rectal carcinomas. Cancer Res 2006, 66:267-82. 10.1158/0008-5472.CAN-05-2533, 16397240.
-
(2006)
Cancer Res
, vol.66
, pp. 267-282
-
-
Grade, M.1
Ghadimi, B.M.2
Varma, S.3
Simon, R.4
Wangsa, D.5
Barenboim-Stapleton, L.6
Liersch, T.7
Becker, H.8
Ried, T.9
Difilippantonio, M.J.10
-
33
-
-
0034053069
-
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus
-
10.1126/science.287.5458.1606, 10733430
-
Peifer M, Polakis P. Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus. Science 2000, 287:1606-9. 10.1126/science.287.5458.1606, 10733430.
-
(2000)
Science
, vol.287
, pp. 1606-1609
-
-
Peifer, M.1
Polakis, P.2
-
34
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
10.1016/S0092-8674(00)00122-7, 11057903
-
Bienz M, Clevers H. Linking colorectal cancer to Wnt signaling. Cell 2000, 103:311-20. 10.1016/S0092-8674(00)00122-7, 11057903.
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
35
-
-
0041380990
-
Adenomatous polyposis coli/beta-catenin interaction and downstream targets: altered gene expression in gastrointestinal tumors
-
10.3816/CCC.2003.n.018, 12952568
-
Clements WM, Lowy AM, Groden J. Adenomatous polyposis coli/beta-catenin interaction and downstream targets: altered gene expression in gastrointestinal tumors. Clin Colorectal Cancer 2003, 3:113-20. 10.3816/CCC.2003.n.018, 12952568.
-
(2003)
Clin Colorectal Cancer
, vol.3
, pp. 113-120
-
-
Clements, W.M.1
Lowy, A.M.2
Groden, J.3
-
36
-
-
0035057699
-
The ABC of APC
-
10.1093/hmg/10.7.721, 11257105
-
Fearnhead NS, Britton MP, Bodmer WF. The ABC of APC. Hum Mol Genet 2001, 10:721-33. 10.1093/hmg/10.7.721, 11257105.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 721-733
-
-
Fearnhead, N.S.1
Britton, M.P.2
Bodmer, W.F.3
-
37
-
-
23844537506
-
Studying the consequences of immediate loss of gene function in the intestine: APC
-
10.1042/BST0330715, 16042569
-
Clarke AR. Studying the consequences of immediate loss of gene function in the intestine: APC. Biochem Soc Trans 2005, 33:665-6. 10.1042/BST0330715, 16042569.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 665-666
-
-
Clarke, A.R.1
-
38
-
-
0025909734
-
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers
-
10.1126/science.1848370, 1848370
-
Kinzler KW, Nilbert MC, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hamilton SR, Hedge P, Markham A, Carlson M, Joslyn G, Groden J, White R, Miki Y, Miyoshi Y, Nishisho I, Nakamura Y. Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science 1991, 251:1366-70. 10.1126/science.1848370, 1848370.
-
(1991)
Science
, vol.251
, pp. 1366-1370
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Vogelstein, B.3
Bryan, T.M.4
Levy, D.B.5
Smith, K.J.6
Preisinger, A.C.7
Hamilton, S.R.8
Hedge, P.9
Markham, A.10
Carlson, M.11
Joslyn, G.12
Groden, J.13
White, R.14
Miki, Y.15
Miyoshi, Y.16
Nishisho, I.17
Nakamura, Y.18
-
39
-
-
1542276493
-
Mouse Models of Intestinal Cancer
-
Boivin GP, Groden J. Mouse Models of Intestinal Cancer. Comp Med 2004, 54:15-8.
-
(2004)
Comp Med
, vol.54
, pp. 15-18
-
-
Boivin, G.P.1
Groden, J.2
-
40
-
-
11244330609
-
Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors
-
Reichling T, Goss KH, Carson DJ. Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors. Cancer Res 2005, 65:166-76.
-
(2005)
Cancer Res
, vol.65
, pp. 166-176
-
-
Reichling, T.1
Goss, K.H.2
Carson, D.J.3
-
41
-
-
0032168375
-
A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice
-
10.1073/pnas.95.18.10826, 27980, 9724789
-
Shoemaker AR, Moser AR, Midgley CA, Clipson L, Newton MA, Dove WF. A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice. PNAS 1998, 95:10826-31. 10.1073/pnas.95.18.10826, 27980, 9724789.
-
(1998)
PNAS
, vol.95
, pp. 10826-10831
-
-
Shoemaker, A.R.1
Moser, A.R.2
Midgley, C.A.3
Clipson, L.4
Newton, M.A.5
Dove, W.F.6
-
42
-
-
3042829472
-
Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function
-
10.1073/pnas.0403338101, 470749, 15210940
-
Haigis KM, Hoff PD, White A, Shoemaker AR, Halberg RB, Dove WF. Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function. PNAS 2004, 101:9769-73. 10.1073/pnas.0403338101, 470749, 15210940.
-
(2004)
PNAS
, vol.101
, pp. 9769-9773
-
-
Haigis, K.M.1
Hoff, P.D.2
White, A.3
Shoemaker, A.R.4
Halberg, R.B.5
Dove, W.F.6
-
43
-
-
9544220659
-
Evolution of the tumor suppressor BRCA1 locus in primates: implications for cancer predisposition
-
10.1093/hmg/ddh301, 15385441
-
Pavlicek A, Noskov VN, Kouprina N, Barrett JC, Jurka J, Larionov V. Evolution of the tumor suppressor BRCA1 locus in primates: implications for cancer predisposition. Hum Mol Genet 2004, 13:2737-51. 10.1093/hmg/ddh301, 15385441.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2737-2751
-
-
Pavlicek, A.1
Noskov, V.N.2
Kouprina, N.3
Barrett, J.C.4
Jurka, J.5
Larionov, V.6
-
44
-
-
34748818856
-
APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice
-
10.1083/jcb.200703186, 2064647, 17893240
-
Caldwell CM, Green RA, Kaplan KB. APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice. J Cell Biol 2007, 178:1109-20. 10.1083/jcb.200703186, 2064647, 17893240.
-
(2007)
J Cell Biol
, vol.178
, pp. 1109-1120
-
-
Caldwell, C.M.1
Green, R.A.2
Kaplan, K.B.3
-
45
-
-
67651007283
-
Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway
-
10.1158/0008-5472.CAN-09-0446, 2775466, 19584276
-
Halberg RB, Waggoner J, Rasmussen K, White A, Clipson L, Prunuske AJ, Bacher JW, Sullivan R, Washington MK, Pitot HC, Petrini JH, Albertson DG, Dove WF. Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway. Cancer Res 2009, 69:5768-75. 10.1158/0008-5472.CAN-09-0446, 2775466, 19584276.
-
(2009)
Cancer Res
, vol.69
, pp. 5768-5775
-
-
Halberg, R.B.1
Waggoner, J.2
Rasmussen, K.3
White, A.4
Clipson, L.5
Prunuske, A.J.6
Bacher, J.W.7
Sullivan, R.8
Washington, M.K.9
Pitot, H.C.10
Petrini, J.H.11
Albertson, D.G.12
Dove, W.F.13
-
46
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
10.1126/science.1133427, 16959974
-
Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE. The consensus coding sequences of human breast and colorectal cancers. Science 2006, 314:268-74. 10.1126/science.1133427, 16959974.
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjöblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
Mandelker, D.7
Leary, R.J.8
Ptak, J.9
Silliman, N.10
Szabo, S.11
Buckhaults, P.12
Farrell, C.13
Meeh, P.14
Markowitz, S.D.15
Willis, J.16
Dawson, D.17
Willson, J.K.18
Gazdar, A.F.19
Hartigan, J.20
Wu, L.21
Liu, C.22
Parmigiani, G.23
Park, B.H.24
Bachman, K.E.25
Papadopoulos, N.26
Vogelstein, B.27
Kinzler, K.W.28
Velculescu, V.E.29
more..
-
47
-
-
0033592960
-
The onset and extent of genomic instability in sporadic colorectal tumor progression
-
10.1073/pnas.96.26.15121, 24783, 10611348
-
Stoler DL, Chen N, Basik M, Kahlenberg MS, Rodriguez-Bigas MA, Petrelli NJ, Anderson GR. The onset and extent of genomic instability in sporadic colorectal tumor progression. PNAS 1999, 96:15121-6. 10.1073/pnas.96.26.15121, 24783, 10611348.
-
(1999)
PNAS
, vol.96
, pp. 15121-15126
-
-
Stoler, D.L.1
Chen, N.2
Basik, M.3
Kahlenberg, M.S.4
Rodriguez-Bigas, M.A.5
Petrelli, N.J.6
Anderson, G.R.7
-
48
-
-
39749137048
-
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer
-
10.1186/gb-2007-8-7-r131, 2323222, 17615082
-
Kaiser S, Park YK, Franklin JL, Halberg RB, Yu M, Jessen WJ, Freudenberg J, Chen X, Haigis K, Jegga AG, Kong S, Sakthivel B, Xu H, Reichling T, Azhar M, Boivin GP, Roberts RB, Bissahoyo AC, Gonzales F, Bloom GC, Eschrich S, Carter SL, Aronow JE, Kleimeyer J, Kleimeyer M, Ramaswamy V, Settle SH, Boone B, Levy S, Graff JM, Doetschman T, Groden J, Dove WF, Threadgill DW, Yeatman TJ, Coffey RJ, Aronow BJ. Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol 2007, 8:R131. 10.1186/gb-2007-8-7-r131, 2323222, 17615082.
-
(2007)
Genome Biol
, vol.8
-
-
Kaiser, S.1
Park, Y.K.2
Franklin, J.L.3
Halberg, R.B.4
Yu, M.5
Jessen, W.J.6
Freudenberg, J.7
Chen, X.8
Haigis, K.9
Jegga, A.G.10
Kong, S.11
Sakthivel, B.12
Xu, H.13
Reichling, T.14
Azhar, M.15
Boivin, G.P.16
Roberts, R.B.17
Bissahoyo, A.C.18
Gonzales, F.19
Bloom, G.C.20
Eschrich, S.21
Carter, S.L.22
Aronow, J.E.23
Kleimeyer, J.24
Kleimeyer, M.25
Ramaswamy, V.26
Settle, S.H.27
Boone, B.28
Levy, S.29
Graff, J.M.30
Doetschman, T.31
Groden, J.32
Dove, W.F.33
Threadgill, D.W.34
Yeatman, T.J.35
Coffey, R.J.36
Aronow, B.J.37
more..
-
49
-
-
35448972047
-
Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation
-
10.1158/0008-5472.CAN-07-2735, 17942902
-
Hinoi T, Akyol A, Theisen BK, Ferguson DO, Greenson JK, Williams BO, Cho KR, Fearon ER. Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation. Cancer Res 2007, 67:9721-30. 10.1158/0008-5472.CAN-07-2735, 17942902.
-
(2007)
Cancer Res
, vol.67
, pp. 9721-9730
-
-
Hinoi, T.1
Akyol, A.2
Theisen, B.K.3
Ferguson, D.O.4
Greenson, J.K.5
Williams, B.O.6
Cho, K.R.7
Fearon, E.R.8
-
50
-
-
77649259311
-
Copy number abnormalities in sporadic canine colorectal cancers
-
10.1101/gr.092726.109, 20086242
-
Tang J, Le S, Sun L, Yan X, Zhang M, Macleod J, Leroy B, Northrup N, Ellis A, Yeatman TJ, Liang Y, Zwick ME, Zhao S. Copy number abnormalities in sporadic canine colorectal cancers. Genome Res 2010, 20:341-50. 10.1101/gr.092726.109, 20086242.
-
(2010)
Genome Res
, vol.20
, pp. 341-350
-
-
Tang, J.1
Le, S.2
Sun, L.3
Yan, X.4
Zhang, M.5
Macleod, J.6
Leroy, B.7
Northrup, N.8
Ellis, A.9
Yeatman, T.J.10
Liang, Y.11
Zwick, M.E.12
Zhao, S.13
|