Mouse Models of Human Cancers (Part 2): Mouse Models of Intestinal Cancer

Comparative Medicine

Volumn 54, Issue 1, 2004, Pages 15-18

  Boivin, Gregory P ^a   Groden, Joanna ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; BASE MISPAIRING; CARCINOGENESIS; COLON CANCER; DIET; GENETIC ENGINEERING; GENETIC SUSCEPTIBILITY; HUMAN; IMMUNE DEFICIENCY; INTESTINE CANCER; INTESTINE FLORA; MISMATCH REPAIR; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOLOGY; PHENOTYPE; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; DISEASE MODEL; GENETICS; INTESTINE TUMOR; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; GENETIC ENGINEERING; HUMANS; INTESTINAL NEOPLASMS; MICE;

EID: 1542276493     PISSN: 15320820     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (6)

1. Boivin, G. P., K. Washington, K. Yang, J. M. Ward, T. P. Pretlow, R. Russell, D. G. Besselsen, V. L. Godfrey, T. Doetschman, W. F. Dove, H. C. Pitot, R. B. Halberg, S. H. Itzkowitz, J. Groden, and R. J. Coffey. 2003. Pathology of mouse models of intestinal cancer: consensus report and recommendations. Gastroenterology 124:762-77.
2. Edelman, W., A. Umar, K. Yang, J. Heyer, M. Kucherlapati, M. Lia, B. Kneitz, E. Avdievich, K. Fan, E. Wong, G. Crouse, T. Kunkel, M. Lipkin, R. D. Kolodner, and R. Kucherlapati. 2000. The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. Cancer Res. 60:803-807.
3. Engle, S. J., J. B. Hoying, G. P. Boivin, I. Ormsby, P. S. Gartside, and T. Doetschman. 1999. Transforming growth factor β1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis. Cancer Res. 59:3379-3386.
4. Kullberg, M.C., J.M. Ward, P. L. Gorelick, P. Caspar, S. Hieny, A. Cheever, D. Jankovic, and A. Sher. 1998. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL12-and gamma interferon-dependent mechanism. Infect. Immun. 66:5157-5166.
5. Oshima, M., H. Oshima, K. Kitagawa, M. Kobayashi, C. Itakura, and M. Taketo. 1995. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncation Apc gene. Proc. Natl. Acad. Sci. USA. 92:4482-4486.
6. Zhu, Y., J. A. Richardson, L. F. Parada, and J. M. Graff. 1998. Smad3 mutant mice develop metastatic colorectal cancer. Cell 94:703-714.