-
2
-
-
62549085750
-
-
International Consortium completes Human Genome Project [National Human Genome Research Institute web site] 14 April 2003
-
International Consortium completes Human Genome Project [National Human Genome Research Institute web site]. http://www.genome.gov/11006929 14 April 2003
-
-
-
-
4
-
-
62549083152
-
-
454 Life Sciences and Baylor College of Medicine Complete Sequencing of DNA Project. [454 Life Sciences website] Accessed 31 May 2007
-
454 Life Sciences and Baylor College of Medicine Complete Sequencing of DNA Project. [454 Life Sciences website] http://www.454.com/news-events/press- releases.asp?display=detail&id=68 Accessed 31 May 2007
-
-
-
-
5
-
-
42249087308
-
The complete genome of an individual by massively parallel DNA sequencing
-
DA Wheeler M Srinivasan M Egholm 2008 The complete genome of an individual by massively parallel DNA sequencing Nature 452 872 876
-
(2008)
Nature
, vol.452
, pp. 872-876
-
-
Wheeler, D.A.1
Srinivasan, M.2
Egholm, M.3
-
6
-
-
0033632161
-
Targets of oncogenes and tumor suppressors: Key for understanding basic mechanisms of carcinogenesis
-
BP Kopnin 2000 Targets of oncogenes and tumor suppressors: key for understanding basic mechanisms of carcinogenesis Biochemistry (Mosc) 65 2 27
-
(2000)
Biochemistry (Mosc)
, vol.65
, pp. 2-27
-
-
Kopnin, B.P.1
-
7
-
-
38749114995
-
Oncogenes and cancer
-
CM Croce 2008 Oncogenes and cancer N Engl J Med 358 502 511
-
(2008)
N Engl J Med
, vol.358
, pp. 502-511
-
-
Croce, C.M.1
-
8
-
-
27144530984
-
An open letter to cancer researchers
-
SJ Elledge GJ Hannon 2005 An open letter to cancer researchers Science 310 439 441
-
(2005)
Science
, vol.310
, pp. 439-441
-
-
Elledge, S.J.1
Hannon, G.J.2
-
9
-
-
34547641984
-
Cancer genome sequencing: The challenges ahead
-
HH Heng 2007 Cancer genome sequencing: the challenges ahead Bioessays 29 783 794
-
(2007)
Bioessays
, vol.29
, pp. 783-794
-
-
Heng, H.H.1
-
10
-
-
33744493093
-
The new era in cancer research
-
H Varmus 2006 The new era in cancer research Science 312 1162 1165
-
(2006)
Science
, vol.312
, pp. 1162-1165
-
-
Varmus, H.1
-
11
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
T Sjöblom S Jones LD Wood 2006 The consensus coding sequences of human breast and colorectal cancers Science 314 268 274
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjöblom, T.1
Jones, S.2
Wood, L.D.3
-
12
-
-
62549121774
-
-
Cancer Sequencing Projects (CSPs) [National Human Genome Research Institute web site]
-
Cancer Sequencing Projects (CSPs) [National Human Genome Research Institute web site]. http://www.genome.gov/19517442
-
-
-
-
13
-
-
36248980204
-
Characterizing the cancer genome in lung adenocarcinoma
-
BA Weir MS Woo G Getz 2007 Characterizing the cancer genome in lung adenocarcinoma Nature 450 893 898
-
(2007)
Nature
, vol.450
, pp. 893-898
-
-
Weir, B.A.1
Woo, M.S.2
Getz, G.3
-
14
-
-
33947393565
-
Mapping the cancer genome. Pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies
-
FS Collins AD Barker 2007 Mapping the cancer genome. Pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies Sci Am 296 50 57
-
(2007)
Sci Am
, vol.296
, pp. 50-57
-
-
Collins, F.S.1
Barker, A.D.2
-
15
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
BJ Druker M Talpaz DJ Resta 2001 Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia N Engl J Med 344 1031 1037
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
16
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
DJ Slamon B Leyland-Jones S Shak 2001 Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2 N Engl J Med 344 783 792
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
17
-
-
0642368571
-
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
-
MC Heinrich CL Corless GD Demetri 2003 Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor J Clin Oncol 21 4342 4349
-
(2003)
J Clin Oncol
, vol.21
, pp. 4342-4349
-
-
Heinrich, M.C.1
Corless, C.L.2
Demetri, G.D.3
-
18
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
JG Paez PA Jänne JC Lee 2004 EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy Science 304 1497 1500
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
-
19
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
W Pao VA Miller KA Politi 2005 Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain LoS Med 2 e73
-
(2005)
LoS Med
, vol.2
, pp. 73
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
-
20
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
S Kobayashi TJ Boggon T Dayaram 2005 EGFR mutation and resistance of non-small-cell lung cancer to gefitinib N Engl J Med 352 786 792
-
(2005)
N Engl J Med
, vol.352
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
-
21
-
-
33646000796
-
Genetics. No longer de-identified
-
AL McGuire RA Gibbs 2006 Genetics. No longer de-identified Science 312 370 371
-
(2006)
Science
, vol.312
, pp. 370-371
-
-
McGuire, A.L.1
Gibbs, R.A.2
-
22
-
-
33751241996
-
Currents in contemporary ethics: Meeting the growing demands of genetic research
-
AL McGuire RA Gibbs 2006 Currents in contemporary ethics: meeting the growing demands of genetic research J Law Med Ethics 34 809 812
-
(2006)
J Law Med Ethics
, vol.34
, pp. 809-812
-
-
McGuire, A.L.1
Gibbs, R.A.2
-
23
-
-
38549085235
-
Research ethics and the challenge of whole genome sequencing
-
AL McGuire T Caulfield MK Cho 2007 Research ethics and the challenge of whole genome sequencing Nat Rev Gen 9 152 156
-
(2007)
Nat Rev Gen
, vol.9
, pp. 152-156
-
-
McGuire, A.L.1
Caulfield, T.2
Cho, M.K.3
-
24
-
-
31644440090
-
Returning genetic research results to individuals: Points to consider
-
G Renegar CJ Webster S Stuerzebecker 2006 Returning genetic research results to individuals: points to consider Bioethics 20 24 36
-
(2006)
Bioethics
, vol.20
, pp. 24-36
-
-
Renegar, G.1
Webster, C.J.2
Stuerzebecker, S.3
-
25
-
-
33750388916
-
The emergence of an ethical duty to disclose genetic research results: International perspectives
-
BM Knoppers Y Joly J Simard 2006 The emergence of an ethical duty to disclose genetic research results: international perspectives Eur J Human Gen 14 1170 1178
-
(2006)
Eur J Human Gen
, vol.14
, pp. 1170-1178
-
-
Knoppers, B.M.1
Joly, Y.2
Simard, J.3
-
26
-
-
30644476605
-
Informing research participants of research results: Analysis of Canadian university based research ethics board policies
-
S MacNeil C Fernandez 2006 Informing research participants of research results: analysis of Canadian university based research ethics board policies J Med Ethics 32 49 54
-
(2006)
J Med Ethics
, vol.32
, pp. 49-54
-
-
MacNeil, S.1
Fernandez, C.2
-
27
-
-
34248647304
-
Reestablishing the researcher-patient compact
-
IS Kohane KD Mandi PL Taylor 2007 Reestablishing the researcher-patient compact Science 316 836 837
-
(2007)
Science
, vol.316
, pp. 836-837
-
-
Kohane, I.S.1
Mandi, K.D.2
Taylor, P.L.3
-
28
-
-
34548680046
-
Comment on "the consensus coding sequences of human breast and colorectal cancers"
-
AF Rubin P Green 2007 Comment on "the consensus coding sequences of human breast and colorectal cancers" Science 317 1500
-
(2007)
Science
, vol.317
, pp. 1500
-
-
Rubin, A.F.1
Green, P.2
-
29
-
-
34548680046
-
Comment on "the consensus coding sequences of human breast and colorectal cancers"
-
G Getz H Höfling JP Mesirov 2007 Comment on "the consensus coding sequences of human breast and colorectal cancers" Science 317 1500
-
(2007)
Science
, vol.317
, pp. 1500
-
-
Getz, G.1
Höfling, H.2
Mesirov, J.P.3
-
30
-
-
34248141223
-
Tumor-stroma interactions in pancreatic ductal adenocarcinoma
-
D Mahadevan DD Von Hoff 2007 Tumor-stroma interactions in pancreatic ductal adenocarcinoma Mol Cancer Ther 6 1186 1197
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1186-1197
-
-
Mahadevan, D.1
Von Hoff, D.D.2
-
31
-
-
34347347171
-
Cancer atlas maps out sample worries
-
E Check 2007 Cancer atlas maps out sample worries Nature 447 1036 1037
-
(2007)
Nature
, vol.447
, pp. 1036-1037
-
-
Check, E.1
-
32
-
-
35048842356
-
Getting to personalized cancer medicine: Taking out the garbage
-
C Compton 2007 Getting to personalized cancer medicine: taking out the garbage Cancer 110 1641 1643
-
(2007)
Cancer
, vol.110
, pp. 1641-1643
-
-
Compton, C.1
-
33
-
-
0036336893
-
Stem-cell origin of metastasis and heterogeneity in solid tumours
-
SM Tu SH Lin CJ Logothetis 2002 Stem-cell origin of metastasis and heterogeneity in solid tumours Lancet Oncol 3 508 513
-
(2002)
Lancet Oncol
, vol.3
, pp. 508-513
-
-
Tu, S.M.1
Lin, S.H.2
Logothetis, C.J.3
-
34
-
-
0020625285
-
Cellular heterogeneity in tumours
-
MF Woodruff 1983 Cellular heterogeneity in tumours Br J Cancer 47 589 594
-
(1983)
Br J Cancer
, vol.47
, pp. 589-594
-
-
Woodruff, M.F.1
-
35
-
-
20244362943
-
Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways
-
JH Kim T Tuziak L Hu 2005 Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways Lab Invest 85 532 549
-
(2005)
Lab Invest
, vol.85
, pp. 532-549
-
-
Kim, J.H.1
Tuziak, T.2
Hu, L.3
-
37
-
-
34248573442
-
An overview of laser microdissection technologies
-
GI Murray 2007 An overview of laser microdissection technologies Acta Histochem 109 171 176
-
(2007)
Acta Histochem
, vol.109
, pp. 171-176
-
-
Murray, G.I.1
-
38
-
-
33847776063
-
Standard operating procedure for the collection of fresh frozen tissue samples
-
SR Mager MH Oomen MM Morente 2007 Standard operating procedure for the collection of fresh frozen tissue samples Eur J Cancer 43 828 834
-
(2007)
Eur J Cancer
, vol.43
, pp. 828-834
-
-
Mager, S.R.1
Oomen, M.H.2
Morente, M.M.3
-
39
-
-
34249789581
-
EGFR and K-ras mutation analysis in non-small cell lung cancer: Comparison of paraffin embedded versus frozen specimens
-
MI Gallegos Ruiz K Floor F Rijmen 2007 EGFR and K-ras mutation analysis in non-small cell lung cancer: comparison of paraffin embedded versus frozen specimens Cell Oncol 29 257 264
-
(2007)
Cell Oncol
, vol.29
, pp. 257-264
-
-
Gallegos Ruiz, M.I.1
Floor, K.2
Rijmen, F.3
-
40
-
-
34347249613
-
Effects of formalin fixation, paraffin embedding, and time of storage on DNA preservation in brain tissue: A BrainNet Europe study
-
I Ferrer J Armstrong S Capellari 2007 Effects of formalin fixation, paraffin embedding, and time of storage on DNA preservation in brain tissue: a BrainNet Europe study Brain Pathol 17 297 303
-
(2007)
Brain Pathol
, vol.17
, pp. 297-303
-
-
Ferrer, I.1
Armstrong, J.2
Capellari, S.3
-
41
-
-
4644371298
-
Optimisation and validation of methods to assess single nucleotide polymorphisms (SNPs) in archival histological material
-
CN Andreassen FB Sørensen J Overgaard 2004 Optimisation and validation of methods to assess single nucleotide polymorphisms (SNPs) in archival histological material Radiother Oncol 72 351 356
-
(2004)
Radiother Oncol
, vol.72
, pp. 351-356
-
-
Andreassen, C.N.1
Sørensen, F.B.2
Overgaard, J.3
-
42
-
-
0031831323
-
Mutation detection and single-molecule counting using isothermal rolling-circle amplification
-
PM Lizardi X Huang Z Zhu 1998 Mutation detection and single-molecule counting using isothermal rolling-circle amplification Nat Genet 19 225 232
-
(1998)
Nat Genet
, vol.19
, pp. 225-232
-
-
Lizardi, P.M.1
Huang, X.2
Zhu, Z.3
-
43
-
-
0034830935
-
Rapid amplification of plasmid and phage DNA using Phi 29 DNA polymerase and multiply-primed rolling circle amplification
-
FB Dean JR Nelson TL Giesler 2001 Rapid amplification of plasmid and phage DNA using Phi 29 DNA polymerase and multiply-primed rolling circle amplification Genome Res 11 1095 1099
-
(2001)
Genome Res
, vol.11
, pp. 1095-1099
-
-
Dean, F.B.1
Nelson, J.R.2
Giesler, T.L.3
-
44
-
-
33748591589
-
Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing
-
R Pinard A de Winter GJ Sarkis 2006 Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing BMC Genomics 7 216
-
(2006)
BMC Genomics
, vol.7
, pp. 216
-
-
Pinard, R.1
De Winter, A.2
Sarkis, G.J.3
-
46
-
-
79951834644
-
-
[Sanger Institute COSMIC website]
-
Catalogue of somatic mutations in cancer [Sanger Institute COSMIC website] http://www.sanger.ac.uk/genetics/CGP/cosmic/
-
Catalogue of Somatic Mutations in Cancer
-
-
-
48
-
-
4043181214
-
Cancer genes and the pathways they control
-
B Vogelstein KW Kinzler 2004 Cancer genes and the pathways they control Nat Med 10 789 799
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
50
-
-
28044467767
-
Management strategies for patients with hereditary pancreatic cancer
-
TA Brentnall 2005 Management strategies for patients with hereditary pancreatic cancer Curr Treat Options Oncol 6 437 445
-
(2005)
Curr Treat Options Oncol
, vol.6
, pp. 437-445
-
-
Brentnall, T.A.1
-
52
-
-
0038179900
-
Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer
-
CD Logsdon DM Simeone C Binkley 2003 Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer Cancer Res 63 2649 2657
-
(2003)
Cancer Res
, vol.63
, pp. 2649-2657
-
-
Logsdon, C.D.1
Simeone, D.M.2
Binkley, C.3
-
53
-
-
28144452515
-
Specialized DNA arrays for the differentiation of pancreatic tumors
-
M Buchholz HA Kestler A Bauer 2005 Specialized DNA arrays for the differentiation of pancreatic tumors Clin Cancer Res 11 8048 8054
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8048-8054
-
-
Buchholz, M.1
Kestler, H.A.2
Bauer, A.3
-
54
-
-
33846115005
-
CancerGenes: A gene selection resource for cancer genome projects
-
ME Higgins M Claremont JE Major 2007 CancerGenes: a gene selection resource for cancer genome projects Nucleic Acids Res 35 D721 D726
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Higgins, M.E.1
Claremont, M.2
Major, J.E.3
-
56
-
-
35748951614
-
Direct selection of human genomic loci by microarray hybridization
-
TJ Albert MN Molla DM Muzny 2007 Direct selection of human genomic loci by microarray hybridization Nat Methods 4 903 905
-
(2007)
Nat Methods
, vol.4
, pp. 903-905
-
-
Albert, T.J.1
Molla, M.N.2
Muzny, D.M.3
-
57
-
-
36549021060
-
Genome-wide in situ exon capture for selective resequencing
-
E Hodges Z Xuan V Balija 2007 Genome-wide in situ exon capture for selective resequencing Nat Genet 39 1522 1527
-
(2007)
Nat Genet
, vol.39
, pp. 1522-1527
-
-
Hodges, E.1
Xuan, Z.2
Balija, V.3
-
58
-
-
62549159721
-
-
[computer program] Institute for Systems Biology
-
Repeat Masker (2003) [computer program] Institute for Systems Biology http://www.repeatmasker.org/
-
(2003)
Repeat Masker
-
-
-
60
-
-
62549115469
-
-
Howard Hughes Medical Institute [Primer3 website]
-
Primer3. Howard Hughes Medical Institute [Primer3 website]. http://frodo.wi.mit.edu/ Accessed 7 Feb 2007
-
Primer3
-
-
-
61
-
-
84871020350
-
-
[UCSC Genome Bioinformatics website]
-
UCSC In-Silico PCR [UCSC Genome Bioinformatics website]. http://genome.ucsc.edu/cgi-bin/hgPcr?command=start
-
UCSC In-Silico PCR
-
-
-
62
-
-
36148937913
-
A pyrosequencing-tailored nucleotide barcode design unveils opportunities for large-scale sample multiplexing
-
P Parameswaran R Jalili L Tao 2007 A pyrosequencing-tailored nucleotide barcode design unveils opportunities for large-scale sample multiplexing Nucleic Acids Res 35 e130
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 130
-
-
Parameswaran, P.1
Jalili, R.2
Tao, L.3
-
63
-
-
0032540905
-
A sequencing method based on real-time pyrophosphate
-
M Ronaghi M Uhlén P Nyrén 1998 A sequencing method based on real-time pyrophosphate Science 28 363 365
-
(1998)
Science
, vol.28
, pp. 363-365
-
-
Ronaghi, M.1
Uhlén, M.2
Nyrén, P.3
-
64
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
M Margulies M Egholm WE Altman 2005 Genome sequencing in microfabricated high-density picolitre reactors Nature 37 376 380
-
(2005)
Nature
, vol.37
, pp. 376-380
-
-
Margulies, M.1
Egholm, M.2
Altman, W.E.3
-
65
-
-
33745926178
-
Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing
-
RK Thomas E Nickerson JF Simons 2006 Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing Nat Med 12 852 855
-
(2006)
Nat Med
, vol.12
, pp. 852-855
-
-
Thomas, R.K.1
Nickerson, E.2
Simons, J.F.3
-
66
-
-
3142780737
-
-
Solexa Ltd
-
Solexa Ltd (2004) Pharmacogenomics 5:433-438
-
(2004)
Pharmacogenomics
, vol.5
, pp. 433-438
-
-
-
68
-
-
62549154234
-
-
Solexa sequencing Technology Illumina website
-
Solexa sequencing Technology Illumina website. http://www.illumina.com/ pages.ilmn?ID=203
-
-
-
-
69
-
-
33845350493
-
Single nucleotide polymorphism array analysis of cancer
-
A Dutt R Beroukhim 2007 Single nucleotide polymorphism array analysis of cancer Curr Opin Oncol 19 43 49
-
(2007)
Curr Opin Oncol
, vol.19
, pp. 43-49
-
-
Dutt, A.1
Beroukhim, R.2
-
70
-
-
33748057487
-
Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays
-
ES Calhoun T Hucl E Gallmeier 2006 Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays Cancer Res 66 7920 7928
-
(2006)
Cancer Res
, vol.66
, pp. 7920-7928
-
-
Calhoun, E.S.1
Hucl, T.2
Gallmeier, E.3
-
71
-
-
41149156431
-
Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays
-
T Harada C Chelala V Bhakta 2008 Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays Oncogene 27 1951 1960
-
(2008)
Oncogene
, vol.27
, pp. 1951-1960
-
-
Harada, T.1
Chelala, C.2
Bhakta, V.3
-
72
-
-
0032991552
-
Characterization of single-nucleotide polymorphisms in coding regions of human genes
-
erratum Nat Genet 23:373
-
Cargill M, Altshuler D, Ireland J et al (1999) Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 22:231-238 (erratum Nat Genet 23:373)
-
(1999)
Nat Genet
, vol.22
, pp. 231-238
-
-
Cargill, M.1
Altshuler, D.2
Al Et, I.J.3
-
73
-
-
0035094764
-
Variation is the spice of life
-
L Kruglyak DA Nickerson 2001 Variation is the spice of life Nat Genet 27 234 236
-
(2001)
Nat Genet
, vol.27
, pp. 234-236
-
-
Kruglyak, L.1
Nickerson, D.A.2
-
74
-
-
13844313862
-
Whole-genome patterns of common DNA variation in three human populations
-
DA Hinds LL Stuve GB Nilsen 2005 Whole-genome patterns of common DNA variation in three human populations Science 307 1072 1079
-
(2005)
Science
, vol.307
, pp. 1072-1079
-
-
Hinds, D.A.1
Stuve, L.L.2
Nilsen, G.B.3
-
75
-
-
33745951429
-
Challenges of SNP genotyping and genetic variation: Its future role in diagnosis and treatment of cancer
-
T Bernig SJ Chanock 2006 Challenges of SNP genotyping and genetic variation: its future role in diagnosis and treatment of cancer Expert Rev Mol Diagn 6 319 331
-
(2006)
Expert Rev Mol Diagn
, vol.6
, pp. 319-331
-
-
Bernig, T.1
Chanock, S.J.2
-
77
-
-
33745951429
-
Challenges of SNP genotyping and genetic variation: Its future role in diagnosis and treatment of cancer
-
T Bernig SJ Chanock 2006 Challenges of SNP genotyping and genetic variation: its future role in diagnosis and treatment of cancer Expert Rev Mol Diagn 6 319 331
-
(2006)
Expert Rev Mol Diagn
, vol.6
, pp. 319-331
-
-
Bernig, T.1
Chanock, S.J.2
-
79
-
-
1642559149
-
Searching for cancer-associated gene polymorphisms: Promises and obstacles
-
EN Imyanitov AV Togo KP Hanson 2004 Searching for cancer-associated gene polymorphisms: promises and obstacles Cancer Lett 204 3 14
-
(2004)
Cancer Lett
, vol.204
, pp. 3-14
-
-
Imyanitov, E.N.1
Togo, A.V.2
Hanson, K.P.3
-
80
-
-
0023223410
-
Localization of the gene for familial adenomatous polyposis on chromosome 5
-
Bodmer WF, Bailey CJ, Bodmer J et al (1987) Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature 19;32:614-616
-
(1987)
Nature
, vol.19
, Issue.32
, pp. 614-616
-
-
Bodmer, W.F.1
Bailey, C.J.2
Al Et, B.J.3
-
81
-
-
0026471719
-
Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22
-
LA Cannon-Albright DE Goldgar LJ Meyer 1992 Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22 Science 258 1148 1152
-
(1992)
Science
, vol.258
, pp. 1148-1152
-
-
Cannon-Albright, L.A.1
Goldgar, D.E.2
Meyer, L.J.3
-
82
-
-
0028006563
-
Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13
-
R Wooster SL Neuhausen J Mangion 1994 Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13 Science 265 2088 2090
-
(1994)
Science
, vol.265
, pp. 2088-2090
-
-
Wooster, R.1
Neuhausen, S.L.2
Mangion, J.3
-
83
-
-
84965187257
-
The age distribution of cancer and a multi-stage theory of carcinogenesis
-
P Armitage R Doll 1954 The age distribution of cancer and a multi-stage theory of carcinogenesis Br J Cancer 8 1 12
-
(1954)
Br J Cancer
, vol.8
, pp. 1-12
-
-
Armitage, P.1
Doll, R.2
-
84
-
-
0027254069
-
How many mutations are required for tumorigenesis? Implications from human cancer data
-
MJ Renan 1993 How many mutations are required for tumorigenesis? Implications from human cancer data Mol Carcinog 7 139 146
-
(1993)
Mol Carcinog
, vol.7
, pp. 139-146
-
-
Renan, M.J.1
-
85
-
-
24944546620
-
Genetic instability in cancer: Theory and experiment
-
RA Beckman LA Loeb 2005 Genetic instability in cancer: theory and experiment Semin Cancer Biol 15 423 435
-
(2005)
Semin Cancer Biol
, vol.15
, pp. 423-435
-
-
Beckman, R.A.1
Loeb, L.A.2
-
86
-
-
0034614637
-
The hallmarks of cancer
-
D Hanahan RA Weinberg 2000 The hallmarks of cancer Cell 100 57 70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
87
-
-
32644463172
-
Generation of mutator mutants during carcinogenesis
-
RN Venkatesan JH Bielas LA Loeb 2006 Generation of mutator mutants during carcinogenesis DNA Repair 5 294 302
-
(2006)
DNA Repair
, vol.5
, pp. 294-302
-
-
Venkatesan, R.N.1
Bielas, J.H.2
Loeb, L.A.3
-
88
-
-
33846504706
-
A "silent" polymorphism in the MDR1 gene changes substrate specificity
-
C Kimchi-Sarfaty JM Oh IW Kim 2007 A "silent" polymorphism in the MDR1 gene changes substrate specificity Science 315 525 528
-
(2007)
Science
, vol.315
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.W.3
-
89
-
-
41649101975
-
The mutant form of Lamin A that causes Hutchinson-Gilford Progeria is a biomarker of cellular aging in human skin
-
D McClintock D Ratner M Lokuge 2007 The mutant form of Lamin A that causes Hutchinson-Gilford Progeria is a biomarker of cellular aging in human skin PLoS ONE 2 e1269
-
(2007)
PLoS ONE
, vol.2
, pp. 1269
-
-
McClintock, D.1
Ratner, D.2
Lokuge, M.3
-
90
-
-
0034101197
-
The 3 untranslated region of messenger RNA: A molecular "hotspot" for pathology?
-
B Conne A Stutz JD Vassalli 2000 The 3 untranslated region of messenger RNA: a molecular "hotspot" for pathology? Nat Med 6 637 641
-
(2000)
Nat Med
, vol.6
, pp. 637-641
-
-
Conne, B.1
Stutz, A.2
Vassalli, J.D.3
-
91
-
-
0037320652
-
Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor
-
J Duan MS Wainwright JM Comeron 2003 Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor Hum Mol Genet 12 205 216
-
(2003)
Hum Mol Genet
, vol.12
, pp. 205-216
-
-
Duan, J.1
Wainwright, M.S.2
Comeron, J.M.3
-
92
-
-
0042359360
-
Functional analysis of human promoter polymorphisms
-
B Hoogendoorn SL Coleman CA Guy 2003 Functional analysis of human promoter polymorphisms Hum Mol Genet 12 2249 2254
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2249-2254
-
-
Hoogendoorn, B.1
Coleman, S.L.2
Guy, C.A.3
-
93
-
-
1942467065
-
Genomic variants in exons and introns: Identifying the splicing spoilers
-
F Pagani FE Baralle 2004 Genomic variants in exons and introns: identifying the splicing spoilers Nat Rev Genet 5 389 396
-
(2004)
Nat Rev Genet
, vol.5
, pp. 389-396
-
-
Pagani, F.1
Baralle, F.E.2
-
94
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
C Greenman P Stephens R Smith 2007 Patterns of somatic mutation in human cancer genomes Nature 446 153 158
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
-
95
-
-
0033006003
-
Allelic discrimination using fluorogenic probes and the 5 nuclease assay
-
KJ Livak 1999 Allelic discrimination using fluorogenic probes and the 5 nuclease assay Genet Anal 14 143 149
-
(1999)
Genet Anal
, vol.14
, pp. 143-149
-
-
Livak, K.J.1
-
96
-
-
20044386880
-
Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay
-
P Hardenbol F Yu J Belmont 2005 Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay Genome Res 15 269 275
-
(2005)
Genome Res
, vol.15
, pp. 269-275
-
-
Hardenbol, P.1
Yu, F.2
Belmont, J.3
-
97
-
-
0036598550
-
SNPstream UHT: Ultra-high throughput SNP genotyping for pharmacogenomics and drug discovery
-
PA Bell S Chaturvedi CA Gelfand 2002 SNPstream UHT: ultra-high throughput SNP genotyping for pharmacogenomics and drug discovery Biotechniques 74 76 77
-
(2002)
Biotechniques
, vol.74
, pp. 76-77
-
-
Bell, P.A.1
Chaturvedi, S.2
Gelfand, C.A.3
-
98
-
-
62549115031
-
-
[Sequenom website]
-
Iplex Gold Review [Sequenom website] http://www.sequenom.com/Genetic- Analysis/Applications/iPLEX-Genotyping/iPLEX-Overview.aspx
-
Iplex Gold Review
-
-
-
100
-
-
84874757605
-
-
[Affymetrix website]
-
Genechip Arrays [Affymetrix website]. http://www.affymetrix.com/products/ arrays/index.affx
-
Genechip Arrays
-
-
-
101
-
-
18144425478
-
A genome-wide scalable SNP genotyping assay using microarray technology
-
KL Gunderson FJ Steemers G Lee 2005 A genome-wide scalable SNP genotyping assay using microarray technology Nat Genet 37 549 554
-
(2005)
Nat Genet
, vol.37
, pp. 549-554
-
-
Gunderson, K.L.1
Steemers, F.J.2
Lee, G.3
-
103
-
-
0030988302
-
P16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma
-
CA Moskaluk RH Hruban SE Kern 1997 p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma Cancer Res 57 2140 2143
-
(1997)
Cancer Res
, vol.57
, pp. 2140-2143
-
-
Moskaluk, C.A.1
Hruban, R.H.2
Kern, S.E.3
-
106
-
-
33845909551
-
The genetics of nicotine dependence: Relationship to pancreatic cancer
-
SL MacLeod P Chowdhury 2006 The genetics of nicotine dependence: relationship to pancreatic cancer World J Gastroenterol 12 7433 7439
-
(2006)
World J Gastroenterol
, vol.12
, pp. 7433-7439
-
-
MacLeod, S.L.1
Chowdhury, P.2
-
107
-
-
0033582099
-
Serum concentrations of organochlorine compounds and K-ras mutations in exocrine pancreatic cancer. PANKRAS II Study Group
-
M Porta N Malats M Jariod 1999 Serum concentrations of organochlorine compounds and K-ras mutations in exocrine pancreatic cancer. PANKRAS II Study Group Lancet 354 2125 2129
-
(1999)
Lancet
, vol.354
, pp. 2125-2129
-
-
Porta, M.1
Malats, N.2
Jariod, M.3
-
108
-
-
0142117205
-
KRAS II Study Group. Occupational exposure to dyes, metals, polycyclic aromatic hydrocarbons and other agents and K-ras activation in human exocrine pancreatic cancer
-
J Alguacil M Porta T Kauppinen 2003 KRAS II Study Group. Occupational exposure to dyes, metals, polycyclic aromatic hydrocarbons and other agents and K-ras activation in human exocrine pancreatic cancer Int J Cancer 107 635 641
-
(2003)
Int J Cancer
, vol.107
, pp. 635-641
-
-
Alguacil, J.1
Porta, M.2
Kauppinen, T.3
-
109
-
-
33749490522
-
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: A meta-analysis
-
SC Larsson E Giovannucci A Wolk 2006 Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis Gastroenterology 131 1271 1283
-
(2006)
Gastroenterology
, vol.131
, pp. 1271-1283
-
-
Larsson, S.C.1
Giovannucci, E.2
Wolk, A.3
-
110
-
-
33847387210
-
Glutathione S-transferase gene polymorphisms and risk and survival of pancreatic cancer
-
L Jiao ML Bondy MM Hassan 2007 Glutathione S-transferase gene polymorphisms and risk and survival of pancreatic cancer Cancer 109 840 848
-
(2007)
Cancer
, vol.109
, pp. 840-848
-
-
Jiao, L.1
Bondy, M.L.2
Hassan, M.M.3
-
111
-
-
34249791474
-
Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians
-
J Chen D Li C Wei 2007 Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians Clin Cancer Res 13 3100 3104
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3100-3104
-
-
Chen, J.1
Li, D.2
Wei, C.3
-
112
-
-
33845624102
-
The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk
-
L Jiao MM Hassan ML Bondy 2007 The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk Cancer Lett 245 61 68
-
(2007)
Cancer Lett
, vol.245
, pp. 61-68
-
-
Jiao, L.1
Hassan, M.M.2
Bondy, M.L.3
-
113
-
-
38849128680
-
XRCC2 and XRCC3 gene polymorphism and risk of pancreatic cancer
-
L Jiao MM Hassan ML Bondy 2007 XRCC2 and XRCC3 gene polymorphism and risk of pancreatic cancer Am J Gastroenterol 16 2379 2386
-
(2007)
Am J Gastroenterol
, vol.16
, pp. 2379-2386
-
-
Jiao, L.1
Hassan, M.M.2
Bondy, M.L.3
-
114
-
-
33746747494
-
Selected polymorphisms of DNA repair genes and risk of pancreatic cancer
-
L Jiao ML Bondy MM Hassan 2006 Selected polymorphisms of DNA repair genes and risk of pancreatic cancer Cancer Detect Prev 30 284 291
-
(2006)
Cancer Detect Prev
, vol.30
, pp. 284-291
-
-
Jiao, L.1
Bondy, M.L.2
Hassan, M.M.3
-
115
-
-
28744457912
-
Genetics of the FANCA gene in familial pancreatic cancer
-
CD Rogers FJ Couch K Brune 2004 Genetics of the FANCA gene in familial pancreatic cancer J Med Genet 41 e126
-
(2004)
J Med Genet
, vol.41
, pp. 126
-
-
Rogers, C.D.1
Couch, F.J.2
Brune, K.3
-
116
-
-
33845885517
-
Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism
-
KL Pogue-Geile R Chen MP Bronner T Crnogorac-Jurcevic 2006 Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism PLoS Med 3 e516
-
(2006)
PLoS Med
, vol.3
, pp. 516
-
-
Pogue-Geile, K.L.1
Chen, R.2
Bronner, M.P.3
Crnogorac-Jurcevic, T.4
-
117
-
-
0029085583
-
Identification of K-ras mutations in pancreatic juice in the early diagnosis of pancreatic cancer
-
P Berthelemy M Bouisson J Escourrou 1995 Identification of K-ras mutations in pancreatic juice in the early diagnosis of pancreatic cancer Ann Intern Med 123 188 191
-
(1995)
Ann Intern Med
, vol.123
, pp. 188-191
-
-
Berthelemy, P.1
Bouisson, M.2
Escourrou, J.3
-
118
-
-
0036239123
-
K-ras, p53, and DPC4 (MAD4) alterations in fine-needle aspirates of the pancreas: A molecular panel correlates with and supplements cytologic diagnosis
-
T van Heek AE Rader JA Offerhaus 2002 K-ras, p53, and DPC4 (MAD4) alterations in fine-needle aspirates of the pancreas: a molecular panel correlates with and supplements cytologic diagnosis Am J Clin Pathol 117 755 765
-
(2002)
Am J Clin Pathol
, vol.117
, pp. 755-765
-
-
Van Heek, T.1
Rader, A.E.2
Offerhaus, J.A.3
-
119
-
-
19944431069
-
Differential diagnosis of pancreatic cancer and focal pancreatitis by using EUS-guided FNA
-
K Takahashi K Yamao K Okubo 2005 Differential diagnosis of pancreatic cancer and focal pancreatitis by using EUS-guided FNA Gastrointest Endosc 61 76 79
-
(2005)
Gastrointest Endosc
, vol.61
, pp. 76-79
-
-
Takahashi, K.1
Yamao, K.2
Okubo, K.3
-
120
-
-
16244401478
-
Immunohistochemical analysis of p53 and MIB-1 in tissue specimens obtained from endoscopic ultrasonography-guided fine needle aspiration biopsy for the diagnosis of solid pancreatic masses
-
T Itoi K Takei A Sofuni 2005 Immunohistochemical analysis of p53 and MIB-1 in tissue specimens obtained from endoscopic ultrasonography-guided fine needle aspiration biopsy for the diagnosis of solid pancreatic masses Oncol Rep 13 229 234
-
(2005)
Oncol Rep
, vol.13
, pp. 229-234
-
-
Itoi, T.1
Takei, K.2
Sofuni, A.3
-
121
-
-
0035380106
-
P53 and K-ras mutations in pancreatic juice samples from patients with chronic pancreatitis
-
M Lohr P Muller J Mora 2001 p53 and K-ras mutations in pancreatic juice samples from patients with chronic pancreatitis Gastrointest Endosc 53 734 743
-
(2001)
Gastrointest Endosc
, vol.53
, pp. 734-743
-
-
Lohr, M.1
Muller, P.2
Mora, J.3
-
122
-
-
0035514157
-
Pancreatic intraductal sampling during ERCP in patients with chronic pancreatitis and pancreatic cancer: Cytologic studies and K-ras-2 codon 12 molecular analysis in 47 cases
-
V Pugliese N Pujic S Saccomanno 2001 Pancreatic intraductal sampling during ERCP in patients with chronic pancreatitis and pancreatic cancer: cytologic studies and K-ras-2 codon 12 molecular analysis in 47 cases Gastrointest Endosc 54 595 599
-
(2001)
Gastrointest Endosc
, vol.54
, pp. 595-599
-
-
Pugliese, V.1
Pujic, N.2
Saccomanno, S.3
-
123
-
-
0032943628
-
Mutational activation of K-ras in nonneoplastic exocrine pancreatic lesions in relation to cigarette smoking status
-
DH Berger H Chang M Wood 1999 Mutational activation of K-ras in nonneoplastic exocrine pancreatic lesions in relation to cigarette smoking status Cancer 85 326 332
-
(1999)
Cancer
, vol.85
, pp. 326-332
-
-
Berger, D.H.1
Chang, H.2
Wood, M.3
-
124
-
-
0028059330
-
Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
-
C Caldas SA Hahn LT da Costa 1994 Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma Nat Genet 8 27 32
-
(1994)
Nat Genet
, vol.8
, pp. 27-32
-
-
Caldas, C.1
Hahn, S.A.2
Da Costa, L.T.3
-
125
-
-
0027404269
-
P53 and K-ras alterations in pancreatic epithelial cell lesions
-
H Kalthoff W Schmiegel C Roeder 2003 p53 and K-ras alterations in pancreatic epithelial cell lesions Oncogene 8 289 298
-
(2003)
Oncogene
, vol.8
, pp. 289-298
-
-
Kalthoff, H.1
Schmiegel, W.2
Roeder, C.3
-
126
-
-
0030988302
-
P16 and K-ras mutations in the intraductal precursors of human pancreatic adenocarcinoma
-
CA Moskaluk RH Hruban SE Kern 1997 p16 and K-ras mutations in the intraductal precursors of human pancreatic adenocarcinoma Cancer Res 57 2140 2143
-
(1997)
Cancer Res
, vol.57
, pp. 2140-2143
-
-
Moskaluk, C.A.1
Hruban, R.H.2
Kern, S.E.3
-
127
-
-
0027232296
-
Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma
-
M Tada M Omata S Kawai 1993 Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma Cancer Res 53 2472 2474
-
(1993)
Cancer Res
, vol.53
, pp. 2472-2474
-
-
Tada, M.1
Omata, M.2
Kawai, S.3
-
128
-
-
0041561141
-
Abnormalities of tumor suppressor gene p16 in pancreatic carcinoma: Immunohistochemical and genetic findings compared with clinicopathological parameters
-
K Ohtsubo H Watanabe Y Yamaguchi 2003 Abnormalities of tumor suppressor gene p16 in pancreatic carcinoma: immunohistochemical and genetic findings compared with clinicopathological parameters J Gastroenterol 38 663 671
-
(2003)
J Gastroenterol
, vol.38
, pp. 663-671
-
-
Ohtsubo, K.1
Watanabe, H.2
Yamaguchi, Y.3
-
129
-
-
17444423293
-
Clinicopathological significance of p53 and mdm2 protein expression in human pancreatic cancer
-
M Dong G Ma W Tu 2003 Clinicopathological significance of p53 and mdm2 protein expression in human pancreatic cancer World J Gastroenterol 11 2162 2165
-
(2003)
World J Gastroenterol
, vol.11
, pp. 2162-2165
-
-
Dong, M.1
Ma, G.2
Tu, W.3
-
130
-
-
0028670932
-
P53 expression in human pancreatic cancer correlates with enhanced biological aggressiveness
-
M Yokoyama Y Yamanaka H Friess 1994 p53 expression in human pancreatic cancer correlates with enhanced biological aggressiveness Anticancer Res 14 2477 2483
-
(1994)
Anticancer Res
, vol.14
, pp. 2477-2483
-
-
Yokoyama, M.1
Yamanaka, Y.2
Friess, H.3
-
131
-
-
0035114253
-
Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo
-
P Ghaneh W Greenhalf M Humphreys 2001 Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo Gene Ther 8 199 208
-
(2001)
Gene Ther
, vol.8
, pp. 199-208
-
-
Ghaneh, P.1
Greenhalf, W.2
Humphreys, M.3
-
132
-
-
0035671396
-
The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma
-
M Tascilar HG Skinner C Rosty 2001 The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma Clin Cancer Res 7 4115 4121
-
(2001)
Clin Cancer Res
, vol.7
, pp. 4115-4121
-
-
Tascilar, M.1
Skinner, H.G.2
Rosty, C.3
-
133
-
-
33947156771
-
Effects of base excision repair gene polymorphisms on pancreatic cancer survival
-
D Li Y Li L Jiao 2007 Effects of base excision repair gene polymorphisms on pancreatic cancer survival Int J Cancer 120 1748 1754
-
(2007)
Int J Cancer
, vol.120
, pp. 1748-1754
-
-
Li, D.1
Li, Y.2
Jiao, L.3
-
134
-
-
33645514237
-
Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival
-
D Li H Liu L Jiao 2006 Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival Cancer Res 66 3323 3330
-
(2006)
Cancer Res
, vol.66
, pp. 3323-3330
-
-
Li, D.1
Liu, H.2
Jiao, L.3
-
135
-
-
33645814832
-
Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer
-
D Li M Frazier DB Evans 2006 Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer J Clin Oncol 24 1720 1728
-
(2006)
J Clin Oncol
, vol.24
, pp. 1720-1728
-
-
Li, D.1
Frazier, M.2
Evans, D.B.3
-
136
-
-
34247149803
-
Impact of epidermal growth factor receptor (EGFR) kinase mutations, EGFR gene amplifications, and KRAS mutations on survival of pancreatic adenocarcinoma
-
J Lee KT Jang CS Ki 2007 Impact of epidermal growth factor receptor (EGFR) kinase mutations, EGFR gene amplifications, and KRAS mutations on survival of pancreatic adenocarcinoma Cancer 109 1561 1569
-
(2007)
Cancer
, vol.109
, pp. 1561-1569
-
-
Lee, J.1
Jang, K.T.2
Ki, C.S.3
-
137
-
-
34447329337
-
Pharmacogenomics of gemcitabine: Can genetic studies lead to tailor-made therapy?
-
H Ueno K Kiyosawa N Kaniwa 2007 Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy? Br J 97 145 151
-
(2007)
Br J
, vol.97
, pp. 145-151
-
-
Ueno, H.1
Kiyosawa, K.2
Kaniwa, N.3
-
138
-
-
33645917374
-
Functional single nucleotide polymorphism haplotypes in the human equilibrative nucleoside transporter 1
-
SN Myers RK Goyal JD Roy 2006 Functional single nucleotide polymorphism haplotypes in the human equilibrative nucleoside transporter 1 Pharmacogenet Genomics 16 315 320
-
(2006)
Pharmacogenet Genomics
, vol.16
, pp. 315-320
-
-
Myers, S.N.1
Goyal, R.K.2
Roy, J.D.3
-
139
-
-
0002831066
-
Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity
-
JR Kroep WJ Loves CL van der Wilt 2002 Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity Mol Cancer Ther 1 371 376
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 371-376
-
-
Kroep, J.R.1
Loves, W.J.2
Van Der Wilt, C.L.3
-
140
-
-
0043163813
-
High-throughput genotyping by DHPLC of the dihydropyrimidine dehydrogenase gene implicated in (fluoro)pyrimidine catabolism
-
E Gross K Seck S Neubauer 2003 High-throughput genotyping by DHPLC of the dihydropyrimidine dehydrogenase gene implicated in (fluoro)pyrimidine catabolism Int J Oncol 22 325 332
-
(2003)
Int J Oncol
, vol.22
, pp. 325-332
-
-
Gross, E.1
Seck, K.2
Neubauer, S.3
-
141
-
-
0035750549
-
Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
-
ST Pullarkat J Stoehlmacher V Ghaderi 2001 Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy Pharmacogenomics J 1 65 70
-
(2001)
Pharmacogenomics J
, vol.1
, pp. 65-70
-
-
Pullarkat, S.T.1
Stoehlmacher, J.2
Ghaderi, V.3
-
142
-
-
0035174375
-
A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer
-
J Stoehlmacher V Ghaderi S Iobal 2001 A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer Anticancer Res 21 3075 3079
-
(2001)
Anticancer Res
, vol.21
, pp. 3075-3079
-
-
Stoehlmacher, J.1
Ghaderi, V.2
Iobal, S.3
-
143
-
-
2342616723
-
Association between polymorphisms of ERCC1 and XPD and survival in non-small-cell lung cancer patients treated with cisplatin combination chemotherapy
-
JS Ryu YC Hong HS Han 2004 Association between polymorphisms of ERCC1 and XPD and survival in non-small-cell lung cancer patients treated with cisplatin combination chemotherapy Lung Cancer 44 311 316
-
(2004)
Lung Cancer
, vol.44
, pp. 311-316
-
-
Ryu, J.S.1
Hong, Y.C.2
Han, H.S.3
-
144
-
-
0035893755
-
A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer
-
DJ Park J Stoehlmacher W Zhang 2001 A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer Cancer Res 61 8654 8658
-
(2001)
Cancer Res
, vol.61
, pp. 8654-8658
-
-
Park, D.J.1
Stoehlmacher, J.2
Zhang, W.3
-
145
-
-
27144532118
-
In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor
-
MS van der Heijden JR Brody DA Dezentje 2005 In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor Clin Cancer Res 11 7508 7515
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7508-7515
-
-
Van Der Heijden, M.S.1
Brody, J.R.2
Dezentje, D.A.3
-
146
-
-
1242273875
-
Farnesyltransferase inhibitors
-
SM Sebti AA Adjei 2004 Farnesyltransferase inhibitors Semin Oncol 31 28 39
-
(2004)
Semin Oncol
, vol.31
, pp. 28-39
-
-
Sebti, S.M.1
Adjei, A.A.2
-
147
-
-
2342645506
-
Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer
-
Van Cutsem E, van de Velde H, Karasek P et al (2004) Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer. J Clin Oncol 22:1430-1438
-
(2004)
J Clin Oncol
, vol.22
, pp. 1430-1438
-
-
Van Cutsem, E.1
Van De Velde, H.2
Al Et, K.P.3
-
149
-
-
0034307305
-
Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells
-
SSW Ng MS Tsao S Chow 2000 Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells Cancer Res 60 5451 5455
-
(2000)
Cancer Res
, vol.60
, pp. 5451-5455
-
-
Ng, S.S.W.1
Tsao, M.S.2
Chow, S.3
-
150
-
-
34249933404
-
National Cancer Institute of Canada Clinical Trials Group. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
MJ Moore D Goldstein J Hamm 2007 National Cancer Institute of Canada Clinical Trials Group. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group J Clin Oncol 25 1960 1966
-
(2007)
J Clin Oncol
, vol.25
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
-
151
-
-
34250828460
-
Pancreatic cancer epidermal growth factor receptor (EGFR) intron 1 polymorphism influences postoperative patient survival and in vitro erlotinib response
-
CW Tzeng A Frolov N Frolova 2007 Pancreatic cancer epidermal growth factor receptor (EGFR) intron 1 polymorphism influences postoperative patient survival and in vitro erlotinib response Ann Surg Oncol 14 2150 2158
-
(2007)
Ann Surg Oncol
, vol.14
, pp. 2150-2158
-
-
Tzeng, C.W.1
Frolov, A.2
Frolova, N.3
-
152
-
-
34948870763
-
Advances in counselling and surveillance of patients at risk for pancreatic cancer
-
RE Brand MM Lerch WS Rubinstein 2007 Advances in counselling and surveillance of patients at risk for pancreatic cancer Gut 56 1460 1469
-
(2007)
Gut
, vol.56
, pp. 1460-1469
-
-
Brand, R.E.1
Lerch, M.M.2
Rubinstein, W.S.3
-
153
-
-
34547424420
-
Strategies for screening for pancreatic adenocarcinoma in high-risk patients
-
MI Canto 2007 Strategies for screening for pancreatic adenocarcinoma in high-risk patients Semin Oncol 34 295 302
-
(2007)
Semin Oncol
, vol.34
, pp. 295-302
-
-
Canto, M.I.1
|