Mycobacterial Phenolic Glycolipid Virulence Factor Biosynthesis: Mechanism and Small-Molecule Inhibition of Polyketide Chain Initiation

Chemistry and Biology

Volumn 15, Issue 1, 2008, Pages 51-61

  Ferreras, Julian A ^a   Stirrett, Karen L ^a   Lu, Xuequan ^b   Ryu, Jae Sang ^b   Soll, Clifford E ^c   Tan, Derek S ^b   Quadri, Luis E N ^a,d  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

^d Weill Cornell Graduate School of Biomedical Sciences   (United States)

Author keywords

CHEMBIO; MICROBIO

Indexed keywords

4 HYDROXYBENZOIC ACID; 4 HYDROXYBENZOIC ACID ESTER; 4-HYDROXYBENZOIC ACID; ADENOSINE; ENZYME INHIBITOR; GLYCOLIPID; LONG CHAIN FATTY ACID COENZYME A LIGASE; MACROLIDE; PHENOL DERIVATIVE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BIOSYNTHESIS; CHEMICAL MODEL; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MYCOBACTERIUM TUBERCULOSIS;

ADENOSINE; COENZYME A LIGASES; ENZYME INHIBITORS; GLYCOLIPIDS; HUMANS; MACROLIDES; MODELS, CHEMICAL; MYCOBACTERIUM TUBERCULOSIS; PARABENS; PHENOLS; VIRULENCE FACTORS;

MYCOBACTERIUM LEPRAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 38349074340     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2007.11.010     Document Type: Article

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