Removal of a methyl group causes global changes in p-hydroxybenzoate hydroxylase

Biochemistry

Volumn 44, Issue 22, 2005, Pages 8047-8058

  Cole, Lindsay J ^a   Gatti, Domenico L ^b   Entsch, Barrie ^a   Ballou, David P ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; CATALYSIS; CONFORMATIONS; CRYSTAL STRUCTURE; ENZYME KINETICS; HYDROXYLATION; MONOMERS; REDUCTION; SOLVENTS;

BACKBONE PEPTIDE LOOPS; FLAVINS; METHYL GROUP; P-HYDROXYBENZOATE HYDROXYLASE (PHBH);

ENZYMES;

4 HYDROXYBENZOATE 3 MONOOXYGENASE; FLAVINE ADENINE NUCLEOTIDE; METHYL GROUP; MONOMER; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SOLVENT; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME CONFORMATION; HYDROXYLATION; KINETICS; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; REDUCTION; STRUCTURE ANALYSIS;

4-HYDROXYBENZOATE-3-MONOOXYGENASE; ALANINE; AMINO ACID SUBSTITUTION; ANAEROBIOSIS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM EXCHANGE MEASUREMENT; DIMERIZATION; GLYCINE; KINETICS; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PROTEIN CONFORMATION; PSEUDOMONAS AERUGINOSA; SPECTROPHOTOMETRY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 20144385856     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050108x     Document Type: Article

References (33)

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