-
2
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki A., Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 2010, 327(5963):291-295.
-
(2010)
Science
, vol.327
, Issue.5963
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
3
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R., et al. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997, 388(6640):394-397.
-
(1997)
Nature
, vol.388
, Issue.6640
, pp. 394-397
-
-
Medzhitov, R.1
-
4
-
-
0033580949
-
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
-
Schwandner R., et al. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J. Biol. Chem. 1999, 274(25):17406-17409.
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.25
, pp. 17406-17409
-
-
Schwandner, R.1
-
5
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi F., et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 2001, 410(6832):1099-1103.
-
(2001)
Nature
, vol.410
, Issue.6832
, pp. 1099-1103
-
-
Hayashi, F.1
-
6
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H., et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000, 408(6813):740-745.
-
(2000)
Nature
, vol.408
, Issue.6813
, pp. 740-745
-
-
Hemmi, H.1
-
7
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou L., et al. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 2001, 413(6857):732-738.
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 732-738
-
-
Alexopoulou, L.1
-
8
-
-
0042307304
-
Viral infection switches non-plasmacytoid dendritic cells into high interferon producers
-
Diebold S.S., et al. Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. Nature 2003, 424(6946):324-328.
-
(2003)
Nature
, vol.424
, Issue.6946
, pp. 324-328
-
-
Diebold, S.S.1
-
9
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
Ozinsky A., et al. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc. Natl. Acad. Sci. U.S.A. 2000, 97(25):13766-13771.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, Issue.25
, pp. 13766-13771
-
-
Ozinsky, A.1
-
10
-
-
0033591330
-
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-κB
-
Inohara N., et al. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-κB. The Journal of biological chemistry 1999, 274(21):14560-14567.
-
(1999)
The Journal of biological chemistry
, vol.274
, Issue.21
, pp. 14560-14567
-
-
Inohara, N.1
-
11
-
-
33750976374
-
5'-Triphosphate RNA is the ligand for RIG-I
-
Hornung V., et al. 5'-Triphosphate RNA is the ligand for RIG-I. Science 2006, 314(5801):994-997.
-
(2006)
Science
, vol.314
, Issue.5801
, pp. 994-997
-
-
Hornung, V.1
-
12
-
-
10344259136
-
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-β promoter
-
Andrejeva J., et al. The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-β promoter. Proc. Natl. Acad. Sci. U.S.A. 2004, 101(49):17264-17269.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, Issue.49
, pp. 17264-17269
-
-
Andrejeva, J.1
-
13
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A., et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 2007, 448(7152):501-505.
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 501-505
-
-
Takaoka, A.1
-
14
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V., et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 2009, 458(7237):514-518.
-
(2009)
Nature
, vol.458
, Issue.7237
, pp. 514-518
-
-
Hornung, V.1
-
16
-
-
48549102504
-
NOD-like receptors (NLRs): bona fide intracellular microbial sensors
-
Shaw M.H., et al. NOD-like receptors (NLRs): bona fide intracellular microbial sensors. Current opinion in immunology 2008, 20(4):377-382.
-
(2008)
Current opinion in immunology
, vol.20
, Issue.4
, pp. 377-382
-
-
Shaw, M.H.1
-
17
-
-
60749104683
-
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
-
Franchi L., et al. The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat. Immunol. 2009, 10(3):241-247.
-
(2009)
Nat. Immunol.
, vol.10
, Issue.3
, pp. 241-247
-
-
Franchi, L.1
-
18
-
-
66749174867
-
The inflammasomes: guardians of the body
-
Martinon F., et al. The inflammasomes: guardians of the body. Annu. Rev. Immunol. 2009, 27:229-265.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 229-265
-
-
Martinon, F.1
-
19
-
-
70449732252
-
Dendritic cell subsets in primary and secondary T cell responses at body surfaces
-
Heath W.R., Carbone F.R. Dendritic cell subsets in primary and secondary T cell responses at body surfaces. Nat. Immunol. 2009, 10(12):1237-1244.
-
(2009)
Nat. Immunol.
, vol.10
, Issue.12
, pp. 1237-1244
-
-
Heath, W.R.1
Carbone, F.R.2
-
20
-
-
70349443224
-
Transcriptional control of the inflammatory response
-
Medzhitov R., Horng T. Transcriptional control of the inflammatory response. Nat. Rev. Immunol. 2009, 9(10):692-703.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, Issue.10
, pp. 692-703
-
-
Medzhitov, R.1
Horng, T.2
-
21
-
-
33745712871
-
Dendritic cells in a mature age
-
Reis e Sousa C. Dendritic cells in a mature age. Nat. Rev. Immunol. 2006, 6(6):476-483.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, Issue.6
, pp. 476-483
-
-
Reis e Sousa, C.1
-
22
-
-
58049209834
-
Inflammatory signals in dendritic cell activation and the induction of adaptive immunity
-
Joffre O., et al. Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol. Rev. 2009, 227(1):234-247.
-
(2009)
Immunol. Rev.
, vol.227
, Issue.1
, pp. 234-247
-
-
Joffre, O.1
-
23
-
-
0242556891
-
Toll-like receptors: balancing host resistance with immune tolerance
-
Pasare C., Medzhitov R. Toll-like receptors: balancing host resistance with immune tolerance. Current opinion in immunology 2003, 15(6):677-682.
-
(2003)
Current opinion in immunology
, vol.15
, Issue.6
, pp. 677-682
-
-
Pasare, C.1
Medzhitov, R.2
-
24
-
-
0017685906
-
Endotoxin and bacteria in portal blood
-
Jacob A.I., et al. Endotoxin and bacteria in portal blood. Gastroenterology 1977, 72(6):1268-1270.
-
(1977)
Gastroenterology
, vol.72
, Issue.6
, pp. 1268-1270
-
-
Jacob, A.I.1
-
25
-
-
0033868803
-
Enteric microflora contribute to constitutive ICAM-1 expression on vascular endothelial cells
-
Komatsu S., et al. Enteric microflora contribute to constitutive ICAM-1 expression on vascular endothelial cells. Am. J. Physiol. Gastrointest Liver Physiol. 2000, 279(1):G186-191.
-
(2000)
Am. J. Physiol. Gastrointest Liver Physiol.
, vol.279
, Issue.1
-
-
Komatsu, S.1
-
26
-
-
0020070480
-
Lack of oral tolerance in C3H/HeJ mice
-
Kiyono H., et al. Lack of oral tolerance in C3H/HeJ mice. J. Exp. Med. 1982, 155(2):605-610.
-
(1982)
J. Exp. Med.
, vol.155
, Issue.2
, pp. 605-610
-
-
Kiyono, H.1
-
27
-
-
0038316325
-
Anatomical basis of tolerance and immunity to intestinal antigens
-
Mowat A.M. Anatomical basis of tolerance and immunity to intestinal antigens. Nat. Rev. Immunol. 2003, 3(4):331-341.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, Issue.4
, pp. 331-341
-
-
Mowat, A.M.1
-
28
-
-
0019776913
-
Endotoxin, reticuloendothelial function, and liver injury
-
Nolan J.P. Endotoxin, reticuloendothelial function, and liver injury. Hepatology Baltimore, Md 1981, 1(5):458-465.
-
(1981)
Hepatology Baltimore, Md
, vol.1
, Issue.5
, pp. 458-465
-
-
Nolan, J.P.1
-
29
-
-
0035670769
-
Scavenger receptor-like receptors for the binding of lipopolysaccharide and lipoteichoic acid to liver endothelial and Kupffer cells
-
van Oosten M., et al. Scavenger receptor-like receptors for the binding of lipopolysaccharide and lipoteichoic acid to liver endothelial and Kupffer cells. Journal of endotoxin research 2001, 7(5):381-384.
-
(2001)
Journal of endotoxin research
, vol.7
, Issue.5
, pp. 381-384
-
-
van Oosten, M.1
-
30
-
-
13444255520
-
Clearance function of scavenger endothelial cells
-
Smedsrod B. Clearance function of scavenger endothelial cells. Comp. Hepatol. 2004, 3(Suppl 1):S22.
-
(2004)
Comp. Hepatol.
, vol.3
, Issue.SUPPL. 1
-
-
Smedsrod, B.1
-
31
-
-
39549097751
-
Liver: An organ with predominant innate immunity
-
Gao B., et al. Liver: An organ with predominant innate immunity. Hepatology Baltimore, Md 2008, 47(2):729-736.
-
(2008)
Hepatology Baltimore, Md
, vol.47
, Issue.2
, pp. 729-736
-
-
Gao, B.1
-
32
-
-
65349104899
-
Intravascular immunity: the host-pathogen encounter in blood vessels
-
Hickey M.J., Kubes P. Intravascular immunity: the host-pathogen encounter in blood vessels. Nat. Rev. Immunol. 2009, 9(5):364-375.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, Issue.5
, pp. 364-375
-
-
Hickey, M.J.1
Kubes, P.2
-
33
-
-
67650750880
-
The liver as a lymphoid organ
-
Crispe I.N. The liver as a lymphoid organ. Annu. Rev. Immunol. 2009, 27:147-163.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 147-163
-
-
Crispe, I.N.1
-
34
-
-
0028917669
-
Human Kupffer cells secrete IL-10 in response to lipopolysaccharide (LPS) challenge
-
Knolle P., et al. Human Kupffer cells secrete IL-10 in response to lipopolysaccharide (LPS) challenge. Journal of hepatology 1995, 22(2):226-229.
-
(1995)
Journal of hepatology
, vol.22
, Issue.2
, pp. 226-229
-
-
Knolle, P.1
-
35
-
-
0025221549
-
Prostanoid release of cultured liver sinusoidal endothelial cells in response to endotoxin and tumor necrosis factor. Comparison with umbilical vein endothelial cells
-
Rieder H., et al. Prostanoid release of cultured liver sinusoidal endothelial cells in response to endotoxin and tumor necrosis factor. Comparison with umbilical vein endothelial cells. Journal of hepatology 1990, 11(3):359-366.
-
(1990)
Journal of hepatology
, vol.11
, Issue.3
, pp. 359-366
-
-
Rieder, H.1
-
36
-
-
0029159792
-
Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation
-
Bissell D.M., et al. Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation. J. Clin. Invest 1995, 96(1):447-455.
-
(1995)
J. Clin. Invest
, vol.96
, Issue.1
, pp. 447-455
-
-
Bissell, D.M.1
-
37
-
-
37749031215
-
Dendritic cells, the liver, and transplantation
-
Sumpter T.L., et al. Dendritic cells, the liver, and transplantation. Hepatology Baltimore, Md 2007, 46(6):2021-2031.
-
(2007)
Hepatology Baltimore, Md
, vol.46
, Issue.6
, pp. 2021-2031
-
-
Sumpter, T.L.1
-
38
-
-
51349131121
-
Mechanism of T cell tolerance induction by murine hepatic Kupffer cells
-
You Q., et al. Mechanism of T cell tolerance induction by murine hepatic Kupffer cells. Hepatology Baltimore, Md 2008, 48(3):978-990.
-
(2008)
Hepatology Baltimore, Md
, vol.48
, Issue.3
, pp. 978-990
-
-
You, Q.1
-
39
-
-
33846212347
-
Ito cells are liver-resident antigen-presenting cells for activating T cell responses
-
Winau F., et al. Ito cells are liver-resident antigen-presenting cells for activating T cell responses. Immunity 2007, 26(1):117-129.
-
(2007)
Immunity
, vol.26
, Issue.1
, pp. 117-129
-
-
Winau, F.1
-
40
-
-
2642674430
-
Hepatocytes induce functional activation of naive CD8+ T lymphocytes but fail to promote survival
-
Bertolino P., et al. Hepatocytes induce functional activation of naive CD8+ T lymphocytes but fail to promote survival. Eur. J. Immunol. 1998, 28(1):221-236.
-
(1998)
Eur. J. Immunol.
, vol.28
, Issue.1
, pp. 221-236
-
-
Bertolino, P.1
-
41
-
-
0034031683
-
Local control of the immune response in the liver
-
Knolle P.A., Gerken G. Local control of the immune response in the liver. Immunol. Rev. 2000, 174:21-34.
-
(2000)
Immunol. Rev.
, vol.174
, pp. 21-34
-
-
Knolle, P.A.1
Gerken, G.2
-
42
-
-
55549148718
-
Poor allostimulatory function of liver plasmacytoid DCs is associated with pro-apoptotic activity, dependent on regulatory T cells
-
Tokita D., et al. Poor allostimulatory function of liver plasmacytoid DCs is associated with pro-apoptotic activity, dependent on regulatory T cells. Journal of hepatology 2008, 49(6):1008-1018.
-
(2008)
Journal of hepatology
, vol.49
, Issue.6
, pp. 1008-1018
-
-
Tokita, D.1
-
43
-
-
37049003544
-
Kupffer cell heterogeneity: functional properties of bone marrow derived and sessile hepatic macrophages
-
Klein I., et al. Kupffer cell heterogeneity: functional properties of bone marrow derived and sessile hepatic macrophages. Blood 2007, 110(12):4077-4085.
-
(2007)
Blood
, vol.110
, Issue.12
, pp. 4077-4085
-
-
Klein, I.1
-
44
-
-
70349229377
-
Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells
-
Schurich A., et al. Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells. Hepatology Baltimore, Md 2009, 50(3):909-919.
-
(2009)
Hepatology Baltimore, Md
, vol.50
, Issue.3
, pp. 909-919
-
-
Schurich, A.1
-
45
-
-
66149152203
-
Systemic antigen cross-presented by liver sinusoidal endothelial cells induces liver-specific CD8 T-cell retention and tolerization
-
von Oppen N., et al. Systemic antigen cross-presented by liver sinusoidal endothelial cells induces liver-specific CD8 T-cell retention and tolerization. Hepatology Baltimore, Md 2009, 49(5):1664-1672.
-
(2009)
Hepatology Baltimore, Md
, vol.49
, Issue.5
, pp. 1664-1672
-
-
von Oppen, N.1
-
46
-
-
0034533209
-
Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance
-
Limmer A., et al. Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance. Nat. Med. 2000, 6(12):1348-1354.
-
(2000)
Nat. Med.
, vol.6
, Issue.12
, pp. 1348-1354
-
-
Limmer, A.1
-
47
-
-
38649137987
-
Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance
-
Diehl L., et al. Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance. Hepatology Baltimore, Md 2008, 47(1):296-305.
-
(2008)
Hepatology Baltimore, Md
, vol.47
, Issue.1
, pp. 296-305
-
-
Diehl, L.1
-
48
-
-
0036715411
-
Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?
-
Lutz M.B., Schuler G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?. Trends in immunology 2002, 23(9):445-449.
-
(2002)
Trends in immunology
, vol.23
, Issue.9
, pp. 445-449
-
-
Lutz, M.B.1
Schuler, G.2
-
49
-
-
4944245002
-
The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity
-
Bowen D.G., et al. The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity. J. Clin. Invest. 2004, 114(5):701-712.
-
(2004)
J. Clin. Invest.
, vol.114
, Issue.5
, pp. 701-712
-
-
Bowen, D.G.1
-
50
-
-
55849093638
-
Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs
-
Luth S., et al. Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs. J. Clin. Invest. 2008, 118(10):3403-3410.
-
(2008)
J. Clin. Invest.
, vol.118
, Issue.10
, pp. 3403-3410
-
-
Luth, S.1
-
51
-
-
0031768675
-
IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules
-
Knolle P.A., et al. IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules. Clin. Exp. Immunol. 1998, 114(3):427-433.
-
(1998)
Clin. Exp. Immunol.
, vol.114
, Issue.3
, pp. 427-433
-
-
Knolle, P.A.1
-
52
-
-
51049123791
-
Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection
-
Das A., et al. Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection. J. Exp. Med. 2008, 205(9):2111-2124.
-
(2008)
J. Exp. Med.
, vol.205
, Issue.9
, pp. 2111-2124
-
-
Das, A.1
-
53
-
-
13544263583
-
Low TLR4 expression by liver dendritic cells correlates with reduced capacity to activate allogeneic T cells in response to endotoxin
-
De Creus A., et al. Low TLR4 expression by liver dendritic cells correlates with reduced capacity to activate allogeneic T cells in response to endotoxin. J. Immunol. 2005, 174(4):2037-2045.
-
(2005)
J. Immunol.
, vol.174
, Issue.4
, pp. 2037-2045
-
-
De Creus, A.1
-
54
-
-
34447338577
-
The role of CD11c(+) hepatic dendritic cells in the induction of innate immune responses
-
Shu S.A., et al. The role of CD11c(+) hepatic dendritic cells in the induction of innate immune responses. Clin. Exp. Immunol. 2007, 149(2):335-343.
-
(2007)
Clin. Exp. Immunol.
, vol.149
, Issue.2
, pp. 335-343
-
-
Shu, S.A.1
-
55
-
-
73349122911
-
NOD2 ligation subverts IFN-α production by liver plasmacytoid dendritic cells and inhibits their T cell allostimulatory activity via B7-H1 up-regulation
-
Castellaneta A., et al. NOD2 ligation subverts IFN-α production by liver plasmacytoid dendritic cells and inhibits their T cell allostimulatory activity via B7-H1 up-regulation. J. Immunol. 2009, 183(11):6922-6932.
-
(2009)
J. Immunol.
, vol.183
, Issue.11
, pp. 6922-6932
-
-
Castellaneta, A.1
-
56
-
-
33748860233
-
Endotoxin modulates the capacity of CpG-activated liver myeloid DCs to direct Th1-type responses
-
Abe M., et al. Endotoxin modulates the capacity of CpG-activated liver myeloid DCs to direct Th1-type responses. Eur. J. Immunol. 2006, 36(9):2483-2493.
-
(2006)
Eur. J. Immunol.
, vol.36
, Issue.9
, pp. 2483-2493
-
-
Abe, M.1
-
57
-
-
33847752705
-
Murine liver plasmacytoid dendritic cells become potent immunostimulatory cells after Flt-3 ligand expansion
-
Kingham T.P., et al. Murine liver plasmacytoid dendritic cells become potent immunostimulatory cells after Flt-3 ligand expansion. Hepatology Baltimore, Md 2007, 45(2):445-454.
-
(2007)
Hepatology Baltimore, Md
, vol.45
, Issue.2
, pp. 445-454
-
-
Kingham, T.P.1
-
58
-
-
44849083915
-
Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells
-
Schildberg F.A., et al. Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells. Eur. J. Immunol. 2008, 38(4):957-967.
-
(2008)
Eur. J. Immunol.
, vol.38
, Issue.4
, pp. 957-967
-
-
Schildberg, F.A.1
-
59
-
-
0029934768
-
Tolerance to rat liver allografts. III. Donor cell migration and tolerance-associated cytokine production in peripheral lymphoid tissues
-
Bishop G.A., et al. Tolerance to rat liver allografts. III. Donor cell migration and tolerance-associated cytokine production in peripheral lymphoid tissues. J. Immunol. 1996, 156(12):4925-4931.
-
(1996)
J. Immunol.
, vol.156
, Issue.12
, pp. 4925-4931
-
-
Bishop, G.A.1
-
60
-
-
33750373677
-
Plasmacytoid dendritic cells do not migrate in intestinal or hepatic lymph
-
Yrlid U., et al. Plasmacytoid dendritic cells do not migrate in intestinal or hepatic lymph. J. Immunol. 2006, 177(9):6115-6121.
-
(2006)
J. Immunol.
, vol.177
, Issue.9
, pp. 6115-6121
-
-
Yrlid, U.1
-
61
-
-
4544358787
-
Migratory responses of murine hepatic myeloid, lymphoid-related, and plasmacytoid dendritic cells to CC chemokines
-
Abe M., et al. Migratory responses of murine hepatic myeloid, lymphoid-related, and plasmacytoid dendritic cells to CC chemokines. Transplantation 2004, 78(5):762-765.
-
(2004)
Transplantation
, vol.78
, Issue.5
, pp. 762-765
-
-
Abe, M.1
-
62
-
-
0035422520
-
Activating immunity in the liver. I. Liver dendritic cells (but not hepatocytes) are potent activators of IFN-gamma release by liver NKT cells
-
Trobonjaca Z., et al. Activating immunity in the liver. I. Liver dendritic cells (but not hepatocytes) are potent activators of IFN-gamma release by liver NKT cells. J. Immunol. 2001, 167(3):1413-1422.
-
(2001)
J. Immunol.
, vol.167
, Issue.3
, pp. 1413-1422
-
-
Trobonjaca, Z.1
-
63
-
-
70449355084
-
In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha
-
Connolly M.K., et al. In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha. J. Clin. Invest. 2009, 119(11):3213-3225.
-
(2009)
J. Clin. Invest.
, vol.119
, Issue.11
, pp. 3213-3225
-
-
Connolly, M.K.1
-
64
-
-
2442652487
-
HSP60 and CpG-DNA-oligonucleotides differentially regulate LPS-tolerance of hepatic Kupffer cells
-
Schuchmann M., et al. HSP60 and CpG-DNA-oligonucleotides differentially regulate LPS-tolerance of hepatic Kupffer cells. Immunology letters 2004, 93(2-3):199-204.
-
(2004)
Immunology letters
, vol.93
, Issue.2-3
, pp. 199-204
-
-
Schuchmann, M.1
-
65
-
-
33846642114
-
The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage
-
Thobe B.M., et al. The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage. Journal of cellular physiology 2007, 210(3):667-675.
-
(2007)
Journal of cellular physiology
, vol.210
, Issue.3
, pp. 667-675
-
-
Thobe, B.M.1
-
66
-
-
77954241472
-
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific
-
Wu J., et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology 2009.
-
(2009)
Immunology
-
-
Wu, J.1
-
67
-
-
0031048379
-
Regulation of endotoxin-induced IL-6 production in liver sinusoidal endothelial cells and Kupffer cells by IL-10
-
Knolle P.A., et al. Regulation of endotoxin-induced IL-6 production in liver sinusoidal endothelial cells and Kupffer cells by IL-10. Clin. Exp. Immunol. 1997, 107(3):555-561.
-
(1997)
Clin. Exp. Immunol.
, vol.107
, Issue.3
, pp. 555-561
-
-
Knolle, P.A.1
-
68
-
-
33750999322
-
Role of Kupffer cells in host defense and liver disease
-
Bilzer M., et al. Role of Kupffer cells in host defense and liver disease. Liver Int. 2006, 26(10):1175-1186.
-
(2006)
Liver Int.
, vol.26
, Issue.10
, pp. 1175-1186
-
-
Bilzer, M.1
-
69
-
-
77949873622
-
An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells
-
Lee W.Y., et al. An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells. Nat. Immunol. 2010, 11(4):295-302.
-
(2010)
Nat. Immunol.
, vol.11
, Issue.4
, pp. 295-302
-
-
Lee, W.Y.1
-
70
-
-
38749146900
-
TLR-dependent cross talk between human Kupffer cells and NK cells
-
Tu Z., et al. TLR-dependent cross talk between human Kupffer cells and NK cells. J. Exp. Med. 2008, 205(1):233-244.
-
(2008)
J. Exp. Med.
, vol.205
, Issue.1
, pp. 233-244
-
-
Tu, Z.1
-
71
-
-
0038185316
-
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
-
Paik Y.H., et al. Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology Baltimore, Md 2003, 37(5):1043-1055.
-
(2003)
Hepatology Baltimore, Md
, vol.37
, Issue.5
, pp. 1043-1055
-
-
Paik, Y.H.1
-
72
-
-
36348997503
-
Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9
-
Watanabe A., et al. Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology Baltimore, Md 2007, 46(5):1509-1518.
-
(2007)
Hepatology Baltimore, Md
, vol.46
, Issue.5
, pp. 1509-1518
-
-
Watanabe, A.1
-
73
-
-
35948958955
-
TLR4 enhances TGF-β signaling and hepatic fibrosis
-
Seki E., et al. TLR4 enhances TGF-β signaling and hepatic fibrosis. Nat. Med. 2007, 13(11):1324-1332.
-
(2007)
Nat. Med.
, vol.13
, Issue.11
, pp. 1324-1332
-
-
Seki, E.1
-
74
-
-
18244364834
-
Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver
-
Uhrig A., et al. Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver. J. Leukoc. Biol. 2005, 77(5):626-633.
-
(2005)
J. Leukoc. Biol.
, vol.77
, Issue.5
, pp. 626-633
-
-
Uhrig, A.1
-
75
-
-
33645757327
-
Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides
-
Martin-Armas M., et al. Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides. Journal of hepatology 2006, 44(5):939-946.
-
(2006)
Journal of hepatology
, vol.44
, Issue.5
, pp. 939-946
-
-
Martin-Armas, M.1
-
76
-
-
72249119475
-
Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity
-
Kern M., et al. Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity. Gastroenterology 2010, 138(1):336-346.
-
(2010)
Gastroenterology
, vol.138
, Issue.1
, pp. 336-346
-
-
Kern, M.1
-
77
-
-
0028095919
-
The acute phase response
-
Baumann H., Gauldie J. The acute phase response. Immunol. Today 1994, 15(2):74-80.
-
(1994)
Immunol. Today
, vol.15
, Issue.2
, pp. 74-80
-
-
Baumann, H.1
Gauldie, J.2
-
78
-
-
37749050365
-
Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice
-
Wu J., et al. Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice. Hepatology Baltimore, Md 2007, 46(6):1769-1778.
-
(2007)
Hepatology Baltimore, Md
, vol.46
, Issue.6
, pp. 1769-1778
-
-
Wu, J.1
-
79
-
-
18344362061
-
Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation
-
Curtsinger J.M., et al. Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation. J. Immunol. 2005, 174(8):4465-4469.
-
(2005)
J. Immunol.
, vol.174
, Issue.8
, pp. 4465-4469
-
-
Curtsinger, J.M.1
-
80
-
-
33748296239
-
Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling
-
Lang K.S., et al. Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling. J. Clin. Invest. 2006, 116(9):2456-2463.
-
(2006)
J. Clin. Invest.
, vol.116
, Issue.9
, pp. 2456-2463
-
-
Lang, K.S.1
-
81
-
-
23944489407
-
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
Napolitani G., et al. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 2005, 6(8):769-776.
-
(2005)
Nat. Immunol.
, vol.6
, Issue.8
, pp. 769-776
-
-
Napolitani, G.1
-
82
-
-
58149292271
-
Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms
-
Popov A., et al. Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms. J. Immunol. 2008, 181(7):4976-4988.
-
(2008)
J. Immunol.
, vol.181
, Issue.7
, pp. 4976-4988
-
-
Popov, A.1
-
83
-
-
0035062597
-
Noncytolytic control of viral infections by the innate and adaptive immune response
-
Guidotti L.G., Chisari F.V. Noncytolytic control of viral infections by the innate and adaptive immune response. Annu. Rev. Immunol. 2001, 19:65-91.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 65-91
-
-
Guidotti, L.G.1
Chisari, F.V.2
-
84
-
-
33746190823
-
Local intrahepatic CD8+ T cell activation by a non-self-antigen results in full functional differentiation
-
Wuensch S.A., et al. Local intrahepatic CD8+ T cell activation by a non-self-antigen results in full functional differentiation. J. Immunol. 2006, 177(3):1689-1697.
-
(2006)
J. Immunol.
, vol.177
, Issue.3
, pp. 1689-1697
-
-
Wuensch, S.A.1
-
85
-
-
33846447768
-
Immune role of hepatic TLR-4 revealed by orthotopic mouse liver transplantation
-
John B., et al. Immune role of hepatic TLR-4 revealed by orthotopic mouse liver transplantation. Hepatology Baltimore, Md 2007, 45(1):178-186.
-
(2007)
Hepatology Baltimore, Md
, vol.45
, Issue.1
, pp. 178-186
-
-
John, B.1
-
86
-
-
12144286763
-
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
-
Tabeta K., et al. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc. Natl. Acad. Sci. U.S.A. 2004, 101(10):3516-3521.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, Issue.10
, pp. 3516-3521
-
-
Tabeta, K.1
-
87
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth S.C., et al. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 2008, 453(7198):1122-1126.
-
(2008)
Nature
, vol.453
, Issue.7198
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
-
88
-
-
13944260898
-
Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function
-
Sporri R., Reis e Sousa C. Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function. Nat. Immunol. 2005, 6(2):163-170.
-
(2005)
Nat. Immunol.
, vol.6
, Issue.2
, pp. 163-170
-
-
Sporri, R.1
Reis e Sousa, C.2
-
89
-
-
67249158956
-
Identification of a dendritic cell receptor that couples sensing of necrosis to immunity
-
Sancho D., et al. Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature 2009, 458(7240):899-903.
-
(2009)
Nature
, vol.458
, Issue.7240
, pp. 899-903
-
-
Sancho, D.1
-
90
-
-
0242579946
-
CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine
-
Curtsinger J.M., et al. CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine. J. Immunol. 2003, 171(10):5165-5171.
-
(2003)
J. Immunol.
, vol.171
, Issue.10
, pp. 5165-5171
-
-
Curtsinger, J.M.1
-
91
-
-
0142092614
-
Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon
-
Le Bon A., et al. Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon. Nat. Immunol. 2003, 4(10):1009-1015.
-
(2003)
Nat. Immunol.
, vol.4
, Issue.10
, pp. 1009-1015
-
-
Le Bon, A.1
-
92
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R. Origin and physiological roles of inflammation. Nature 2008, 454(7203):428-435.
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 428-435
-
-
Medzhitov, R.1
-
93
-
-
58049220365
-
Pattern recognition receptors and control of adaptive immunity
-
Palm N.W., Medzhitov R. Pattern recognition receptors and control of adaptive immunity. Immunol. Rev. 2009, 227(1):221-233.
-
(2009)
Immunol. Rev.
, vol.227
, Issue.1
, pp. 221-233
-
-
Palm, N.W.1
Medzhitov, R.2
-
94
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β-dependent adaptive immunity against tumors
-
Ghiringhelli F., et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β-dependent adaptive immunity against tumors. Nat. Med. 2009, 15(10):1170-1178.
-
(2009)
Nat. Med.
, vol.15
, Issue.10
, pp. 1170-1178
-
-
Ghiringhelli, F.1
-
95
-
-
0034813206
-
Endothelial cell-mediated uptake of a hepatitis B virus: a new concept of liver targeting of hepatotropic microorganisms
-
Breiner K.M., et al. Endothelial cell-mediated uptake of a hepatitis B virus: a new concept of liver targeting of hepatotropic microorganisms. Hepatology Baltimore, Md 2001, 343(4 Pt 1):803-808.
-
(2001)
Hepatology Baltimore, Md
, vol.343
, Issue.4 PART 1
, pp. 803-808
-
-
Breiner, K.M.1
-
96
-
-
4644236862
-
L-SIGN (CD209L) and DCs-SIGN (CD209) mediate transinfection of liver cells by hepatitis C virus
-
Cormier E.G., et al. L-SIGN (CD209L) and DCs-SIGN (CD209) mediate transinfection of liver cells by hepatitis C virus. Proc. Natl. Acad. Sci. U.S.A. 2004, 101(39):14067-14072.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, Issue.39
, pp. 14067-14072
-
-
Cormier, E.G.1
-
97
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S., Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 2004, 4(7):499-511.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, Issue.7
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
98
-
-
50049123401
-
Chemokines and leukocyte traffic
-
Sallusto F., Baggiolini M. Chemokines and leukocyte traffic. Nat. Immunol. 2008, 9(9):949-952.
-
(2008)
Nat. Immunol.
, vol.9
, Issue.9
, pp. 949-952
-
-
Sallusto, F.1
Baggiolini, M.2
-
99
-
-
0034775153
-
Toll-like receptors control activation of adaptive immune responses
-
Schnare M., et al. Toll-like receptors control activation of adaptive immune responses. Nat. Immunol. 2001, 2(10):947-950.
-
(2001)
Nat. Immunol.
, vol.2
, Issue.10
, pp. 947-950
-
-
Schnare, M.1
-
100
-
-
74549216531
-
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effectorcytolytic T cells
-
Pipkin, M.E. et al. Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effectorcytolytic T cells. Immunity.
-
Immunity
-
-
Pipkin, M.E.1
-
101
-
-
20044382430
-
Toll-like receptor 3 promotes cross-priming to virus-infected cells
-
Schulz O., et al. Toll-like receptor 3 promotes cross-priming to virus-infected cells. Nature 2005, 433(7028):887-892.
-
(2005)
Nature
, vol.433
, Issue.7028
, pp. 887-892
-
-
Schulz, O.1
-
102
-
-
35748964708
-
Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity
-
Krieg A.M., Vollmer J. Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity. Immunol. Rev. 2007, 220:251-269.
-
(2007)
Immunol. Rev.
, vol.220
, pp. 251-269
-
-
Krieg, A.M.1
Vollmer, J.2
|