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Volumn 2, Issue 4, 2010, Pages 521-537

Suicide gene therapy for graft-versus-host disease

Author keywords

allogeneic stem cell transplantation; cytosine deaminase; donor lymphocyte infusion; graft versus host disease; graft versus infection; graft versus leukemia; herpes simplex virus thymidine kinase; selection marker; suicide gene therapy

Indexed keywords

CLINICAL ASSESSMENT; CLINICAL TRIAL; GENE EXPRESSION; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; REVIEW; SUICIDE GENE; SUICIDE GENE THERAPY; TARGET CELL;

EID: 77954966694     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/imt.10.19     Document Type: Review
Times cited : (4)

References (167)
  • 1
    • 0025100777 scopus 로고
    • Graft-versus-leukemia reactions after bone marrow transplantation
    • Horowitz MM, Gale RP, Sondel PM et al.: Graft-versus-leukemia reactions after bone marrow transplantation. Blood 75(3), 555-562 (1990).
    • (1990) Blood , vol.75 , Issue.3 , pp. 555-562
    • Horowitz, M.M.1    Gale, R.P.2    Sondel, P.M.3
  • 2
    • 56349088288 scopus 로고    scopus 로고
    • Donor lymphocyte infusions: The long and winding road: How should it be traveled?
    • Tomblyn M, Lazarus HM: Donor lymphocyte infusions: the long and winding road: how should it be traveled? Bone Marrow Transplant. 42(9), 569-579 (2008).
    • (2008) Bone Marrow Transplant. , vol.42 , Issue.9 , pp. 569-579
    • Tomblyn, M.1    Lazarus, H.M.2
  • 3
    • 0029100438 scopus 로고
    • Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients
    • Kolb HJ, Schattenberg A, Goldman JM et al.: Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. Blood 86(5), 2041-2050 (1995).
    • (1995) Blood , vol.86 , Issue.5 , pp. 2041-2050
    • Kolb, H.J.1    Schattenberg, A.2    Goldman, J.M.3
  • 4
    • 0026602322 scopus 로고
    • Donor leukocyte infusions for chronic myeloid leukemia in relapse after allogeneic bone marrow transplantation
    • Cullis JO, Jiang YZ, Schwarer AP, Hughes TP, Barrett AJ, Goldman JM: Donor leukocyte infusions for chronic myeloid leukemia in relapse after allogeneic bone marrow transplantation. Blood 79(5), 1379-1381 (1992).
    • (1992) Blood , vol.79 , Issue.5 , pp. 1379-1381
    • Cullis, J.O.1    Jiang, Y.Z.2    Schwarer, A.P.3    Hughes, T.P.4    Barrett, A.J.5    Goldman, J.M.6
  • 5
    • 0027437385 scopus 로고
    • Salvage immunotherapy using donor leukocyte infusions as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation: Efficacy and toxicity of a defined T-cell dose
    • Drobyski WR, Keever CA, Roth MS et al.: Salvage immunotherapy using donor leukocyte infusions as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation: efficacy and toxicity of a defined T-cell dose. Blood 82(8), 2310-2318 (1993).
    • (1993) Blood , vol.82 , Issue.8 , pp. 2310-2318
    • Drobyski, W.R.1    Keever, C.A.2    Roth, M.S.3
  • 6
    • 0028237517 scopus 로고
    • Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: The case for giving donor leukocyte transfusions before the onset of hematologic relapse
    • van Rhee F, Lin F, Cullis JO et al.: Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor leukocyte transfusions before the onset of hematologic relapse. Blood 83(11), 3377-3383 (1994).
    • (1994) Blood , vol.83 , Issue.11 , pp. 3377-3383
    • Van Rhee, F.1    Lin, F.2    Cullis, J.O.3
  • 7
    • 23444449333 scopus 로고
    • Induction of graft-versus-host disease as immunotherapy for relapsed chronic myeloid leukemia
    • Porter DL, Roth MS, McGarigle C, Ferrara JL, Antin JH: Induction of graft-versus-host disease as immunotherapy for relapsed chronic myeloid leukemia. N. Engl. J. Med. 330(2), 100-106 (1994).
    • (1994) N. Engl. J. Med. , vol.330 , Issue.2 , pp. 100-106
    • Porter, D.L.1    Roth, M.S.2    McGarigle, C.3    Ferrara, J.L.4    Antin, J.H.5
  • 8
    • 0029092530 scopus 로고
    • Adoptive immunotherapy evaluating escalating doses of donor leukocytes for relapse of chronic myeloid leukemia after bone marrow transplantation: Separation of graft-versus-leukemia responses from graft-versus-host disease
    • Mackinnon S, Papadopoulos EB, Carabasi MH et al.: Adoptive immunotherapy evaluating escalating doses of donor leukocytes for relapse of chronic myeloid leukemia after bone marrow transplantation: Separation of graft-versus-leukemia responses from graft-versus-host disease. Blood 86(4), 1261-1268 (1995).
    • (1995) Blood , vol.86 , Issue.4 , pp. 1261-1268
    • MacKinnon, S.1    Papadopoulos, E.B.2    Carabasi, M.H.3
  • 10
    • 2942712161 scopus 로고    scopus 로고
    • Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation
    • Collins RH, Jr., Shpilberg O, Drobyski WR et al.: Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation. J. Clin. Oncol. 15(2), 433-444 (1997).
    • (1997) J. Clin. Oncol. , vol.15 , Issue.2 , pp. 433-444
    • Collins Jr., R.H.1    Shpilberg, O.2    Drobyski, W.R.3
  • 11
    • 0033015210 scopus 로고    scopus 로고
    • Comparative outcomes of T-cell-depleted and non-T-cell-depleted allogeneic bone marrow transplantation for chronic myelogenous leukemia: Impact of donor lymphocyte infusion
    • Sehn LH, Alyea EP, Weller E et al.: Comparative outcomes of T-cell-depleted and non-T-cell-depleted allogeneic bone marrow transplantation for chronic myelogenous leukemia: Impact of donor lymphocyte infusion. J. Clin. Oncol. 17(2), 561-568 (1999).
    • (1999) J. Clin. Oncol. , vol.17 , Issue.2 , pp. 561-568
    • Sehn, L.H.1    Alyea, E.P.2    Weller, E.3
  • 12
    • 0031869178 scopus 로고    scopus 로고
    • Donor lymphocyte infusion for the treatment of relapse after allogeneic hematopoietic stem cell transplantation
    • Helg C, Starobinski M, Jeannet M, Chapuis B: Donor lymphocyte infusion for the treatment of relapse after allogeneic hematopoietic stem cell transplantation. Leuk. Lymphoma 29(3-4), 301-313 (1998)
    • (1998) Leuk. Lymphoma , vol.29 , Issue.3-4 , pp. 301-313
    • Helg, C.1    Starobinski, M.2    Jeannet, M.3    Chapuis, B.4
  • 13
    • 0032558759 scopus 로고    scopus 로고
    • Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype
    • Aversa F, Tabilio A, Velardi A et al.: Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype. N. Engl. J. Med. 339(17), 1186-1193 (1998).
    • (1998) N. Engl. J. Med. , vol.339 , Issue.17 , pp. 1186-1193
    • Aversa, F.1    Tabilio, A.2    Velardi, A.3
  • 14
    • 1442360601 scopus 로고    scopus 로고
    • Enhancement of allogeneic hematopoietic stem cell engraftment and prevention of GVHD by intra-bone marrow bone marrow transplantation plus donor lymphocyte infusion
    • Nakamura K, Inaba M, Sugiura K et al.: Enhancement of allogeneic hematopoietic stem cell engraftment and prevention of GVHD by intra-bone marrow bone marrow transplantation plus donor lymphocyte infusion. Stem Cells 22(2), 125-134 (2004).
    • (2004) Stem Cells , vol.22 , Issue.2 , pp. 125-134
    • Nakamura, K.1    Inaba, M.2    Sugiura, K.3
  • 16
    • 0025087325 scopus 로고
    • A retrospective analysis of therapy for acute graft-versus-host disease: Initial treatment
    • Martin PJ, Schoch G, Fisher L et al.: A retrospective analysis of therapy for acute graft-versus-host disease: initial treatment. Blood 76(8), 1464-1472 (1990).
    • (1990) Blood , vol.76 , Issue.8 , pp. 1464-1472
    • Martin, P.J.1    Schoch, G.2    Fisher, L.3
  • 17
    • 0037978047 scopus 로고    scopus 로고
    • Pathogenesis and treatment of graft-versus-host disease after bone marrow transplant
    • Vogelsang GB, Lee L, Bensen-Kennedy DM: Pathogenesis and treatment of graft-versus-host disease after bone marrow transplant. Annu. Rev. Med. 54, 29-52 (2003).
    • (2003) Annu. Rev. Med. , vol.54 , pp. 29-52
    • Vogelsang, G.B.1    Lee, L.2    Bensen-Kennedy, D.M.3
  • 18
    • 0025963233 scopus 로고
    • Graft-versus-host disease
    • Ferrara JL, Deeg HJ: Graft-versus-host disease. N. Engl. J. Med. 324(10), 667-674 (1991).
    • (1991) N. Engl. J. Med. , vol.324 , Issue.10 , pp. 667-674
    • Ferrara, J.L.1    Deeg, H.J.2
  • 19
    • 0025860239 scopus 로고
    • Chronic graft-versus-host disease and other late complications of bone marrow transplantation
    • Sullivan KM, Agura E, Anasetti C et al.: Chronic graft-versus-host disease and other late complications of bone marrow transplantation. Semin. Hematol. 28(3), 250-259 (1991).
    • (1991) Semin. Hematol. , vol.28 , Issue.3 , pp. 250-259
    • Sullivan, K.M.1    Agura, E.2    Anasetti, C.3
  • 20
    • 0026654073 scopus 로고
    • Late complications of allogeneic and autologous marrow transplantation
    • Sullivan KM, Mori M, Sanders J et al.: Late complications of allogeneic and autologous marrow transplantation. Bone Marrow Transplant. 10(Suppl. 1), 127-134 (1992).
    • (1992) Bone Marrow Transplant. , vol.10 , Issue.SUPPL. 1 , pp. 127-134
    • Sullivan, K.M.1    Mori, M.2    Sanders, J.3
  • 22
    • 44049086872 scopus 로고    scopus 로고
    • GvHD pathophysiology: Is acute different from chronic?
    • Toubai T, Sun Y, Reddy P: GvHD pathophysiology: is acute different from chronic? Best Pract. Res. Clin. Haematol. 21(2), 101-117 (2008).
    • (2008) Best Pract. Res. Clin. Haematol. , vol.21 , Issue.2 , pp. 101-117
    • Toubai, T.1    Sun, Y.2    Reddy, P.3
  • 23
    • 0032533591 scopus 로고    scopus 로고
    • Kinetics of the graft-versus-leukemia response after donor leukocyte infusions for relapsed chronic myeloid leukemia after allogeneic bone marrow transplantation
    • Baurmann H, Nagel S, Binder T, Neubauer A, Siegert W, Huhn D: Kinetics of the graft-versus-leukemia response after donor leukocyte infusions for relapsed chronic myeloid leukemia after allogeneic bone marrow transplantation. Blood 92(10), 3582-3590 (1998).
    • (1998) Blood , vol.92 , Issue.10 , pp. 3582-3590
    • Baurmann, H.1    Nagel, S.2    Binder, T.3    Neubauer, A.4    Siegert, W.5    Huhn, D.6
  • 24
    • 0037105380 scopus 로고    scopus 로고
    • Aberrant regulation of superantigen responses during T-cell reconstitution and graft-versus-host disease in immunodeficient mice
    • Spaner D, Sheng-Tanner X, Schuh AC: Aberrant regulation of superantigen responses during T-cell reconstitution and graft-versus-host disease in immunodeficient mice. Blood 100(6), 2216-2224 (2002).
    • (2002) Blood , vol.100 , Issue.6 , pp. 2216-2224
    • Spaner, D.1    Sheng-Tanner, X.2    Schuh, A.C.3
  • 25
    • 0034019523 scopus 로고    scopus 로고
    • Changes in T cell receptor repertoire associated with graft-versus-tumor effect and graft-versus-host disease in patients with relapsed multiple myeloma after donor lymphocyte infusion
    • Orsini E, Alyea EP, Schlossman R et al.: Changes in T cell receptor repertoire associated with graft-versus-tumor effect and graft-versus-host disease in patients with relapsed multiple myeloma after donor lymphocyte infusion. Bone Marrow Transplant. 25(6), 623-632 (2000).
    • (2000) Bone Marrow Transplant. , vol.25 , Issue.6 , pp. 623-632
    • Orsini, E.1    Alyea, E.P.2    Schlossman, R.3
  • 26
    • 34247493188 scopus 로고    scopus 로고
    • Naturally occurring regulatory T cells: Recent insights in health and disease
    • Raimondi G, Turner MS, Thomson AW, Morel PA: Naturally occurring regulatory T cells: recent insights in health and disease. Crit. Rev. Immunol. 27(1), 61-95 (2007).
    • (2007) Crit. Rev. Immunol. , vol.27 , Issue.1 , pp. 61-95
    • Raimondi, G.1    Turner, M.S.2    Thomson, A.W.3    Morel, P.A.4
  • 29
    • 1642494602 scopus 로고    scopus 로고
    • +CD25+ immunoregulatory T cells for the control of graft-versus-host disease after allogeneic hematopoietic stem-cell transplantation
    • +CD25+ immunoregulatory T cells for the control of graft-versus-host disease after allogeneic hematopoietic stem-cell transplantation. Transplantation 77(1 Suppl.), S32-S34 (2004).
    • (2004) Transplantation , vol.77 , Issue.1 SUPPL.
    • Trenado, A.1    Fisson, S.2    Braunberger, E.3    Klatzmann, D.4    Salomon, B.L.5    Cohen, J.L.6
  • 30
    • 0013989358 scopus 로고
    • The biology of graft-versus-host reactions
    • Billingham RE: The biology of graft-versus-host reactions. Harvey Lect. 62, 21-78 (1966).
    • (1966) Harvey Lect. , vol.62 , pp. 21-78
    • Billingham, R.E.1
  • 31
    • 0029164624 scopus 로고
    • The significance of HLA-DRB1 matching on clinical outcome after HLA-A, B, DR identical unrelated donor marrow transplantation
    • Petersdorf EW, Longton GM, Anasetti C et al.: The significance of HLA-DRB1 matching on clinical outcome after HLA-A, B, DR identical unrelated donor marrow transplantation. Blood 86(4), 1606-1613 (1995).
    • (1995) Blood , vol.86 , Issue.4 , pp. 1606-1613
    • Petersdorf, E.W.1    Longton, G.M.2    Anasetti, C.3
  • 33
    • 34447342881 scopus 로고    scopus 로고
    • HLA association with hematopoietic stem cell transplantation outcome: The number of mismatches at HLA-A, -B, -C, -DRB1, or -DQB1 is strongly associated with overall survival
    • Loiseau P, Busson M, Balere ML et al.: HLA association with hematopoietic stem cell transplantation outcome: the number of mismatches at HLA-A, -B, -C, -DRB1, or -DQB1 is strongly associated with overall survival. Biol. Blood Marrow Transplant. 13(8), 965-974 (2007).
    • (2007) Biol. Blood Marrow Transplant. , vol.13 , Issue.8 , pp. 965-974
    • Loiseau, P.1    Busson, M.2    Balere, M.L.3
  • 34
    • 0032188990 scopus 로고    scopus 로고
    • Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation
    • Ratanatharathorn V, Nash RA, Przepiorka D et al.: Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation. Blood 92(7), 2303-2314 (1998).
    • (1998) Blood , vol.92 , Issue.7 , pp. 2303-2314
    • Ratanatharathorn, V.1    Nash, R.A.2    Przepiorka, D.3
  • 35
    • 0024503220 scopus 로고
    • Graft-v-host disease is associated with autoimmune-like thrombocytopenia
    • Anasetti C, Rybka W, Sullivan KM, Banaji M, Slichter SJ: Graft-v-host disease is associated with autoimmune-like thrombocytopenia. Blood 73(4), 1054-1058 (1989).
    • (1989) Blood , vol.73 , Issue.4 , pp. 1054-1058
    • Anasetti, C.1    Rybka, W.2    Sullivan, K.M.3    Banaji, M.4    Slichter, S.J.5
  • 36
    • 4644359708 scopus 로고    scopus 로고
    • Impact of HLA Class i and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome
    • Flomenberg N, Baxter-Lowe LA, Confer D et al.: Impact of HLA Class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood 104(7), 1923-1930 (2004).
    • (2004) Blood , vol.104 , Issue.7 , pp. 1923-1930
    • Flomenberg, N.1    Baxter-Lowe, L.A.2    Confer, D.3
  • 37
    • 13344278000 scopus 로고    scopus 로고
    • Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantation
    • Goulmy E, Schipper R, Pool J et al.: Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantation. N. Engl. J. Med. 334(5), 281-285 (1996).
    • (1996) N. Engl. J. Med. , vol.334 , Issue.5 , pp. 281-285
    • Goulmy, E.1    Schipper, R.2    Pool, J.3
  • 38
    • 0025730487 scopus 로고
    • Growth inhibition of clonogenic leukemic precursor cells by minor histocompatibility antigen-specific cytotoxic T lymphocytes
    • Falkenburg JH, Goselink HM, van der Harst D et al.: Growth inhibition of clonogenic leukemic precursor cells by minor histocompatibility antigen-specific cytotoxic T lymphocytes. J. Exp. Med. 174(1), 27-33 (1991).
    • (1991) J. Exp. Med. , vol.174 , Issue.1 , pp. 27-33
    • Falkenburg, J.H.1    Goselink, H.M.2    Van Der Harst, D.3
  • 39
    • 0033485649 scopus 로고    scopus 로고
    • Recipient tumor necrosis factor-α and interleukin-10 gene polymorphisms associate with early mortality and acute graft-versus-host disease severity in HLA-matched sibling bone marrow transplants
    • Cavet J, Middleton PG, Segall M, Noreen H, Davies SM, Dickinson AM: Recipient tumor necrosis factor-α and interleukin-10 gene polymorphisms associate with early mortality and acute graft-versus-host disease severity in HLA-matched sibling bone marrow transplants. Blood 94(11), 3941-3946 (1999).
    • (1999) Blood , vol.94 , Issue.11 , pp. 3941-3946
    • Cavet, J.1    Middleton, P.G.2    Segall, M.3    Noreen, H.4    Davies, S.M.5    Dickinson, A.M.6
  • 40
    • 84983719872 scopus 로고    scopus 로고
    • Relation of an interleukin-10 promoter polymorphism to graft-versus-host disease and survival after hematopoietic-cell transplantation
    • Lin MT, Storer B, Martin PJ et al.: Relation of an interleukin-10 promoter polymorphism to graft-versus-host disease and survival after hematopoietic-cell transplantation. N. Engl. J. Med. 349(23), 2201-2210 (2003).
    • (2003) N. Engl. J. Med. , vol.349 , Issue.23 , pp. 2201-2210
    • Lin, M.T.1    Storer, B.2    Martin, P.J.3
  • 41
    • 23944460869 scopus 로고    scopus 로고
    • Non-HLA immunogenetics in hematopoietic stem cell transplantation
    • DOI 10.1016/j.coi.2005.07.017, PII S0952791505001214
    • Dickinson AM, Charron D: Non-HLA immunogenetics in hematopoietic stem cell transplantation. Curr. Opin. Immunol. 17(5), 517-525 (2005). (Pubitemid 41207956)
    • (2005) Current Opinion in Immunology , vol.17 , Issue.5 , pp. 517-525
    • Dickinson, A.M.1    Charron, D.2
  • 42
    • 20144388509 scopus 로고    scopus 로고
    • Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
    • Miller JS, Soignier Y, Panoskaltsis-Mortari A et al.: Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood 105(8), 3051-3057 (2005).
    • (2005) Blood , vol.105 , Issue.8 , pp. 3051-3057
    • Miller, J.S.1    Soignier, Y.2    Panoskaltsis-Mortari, A.3
  • 43
    • 34247581578 scopus 로고    scopus 로고
    • Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GvHD) following unrelated donor allogeneic hct
    • Miller JS, Cooley S, Parham P et al.: Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GvHD) following unrelated donor allogeneic hct. Blood 109(11), 5058-5061 (2007).
    • (2007) Blood , vol.109 , Issue.11 , pp. 5058-5061
    • Miller, J.S.1    Cooley, S.2    Parham, P.3
  • 44
    • 0036716947 scopus 로고    scopus 로고
    • NK cells: A lesson from mismatched hematopoietic transplantation
    • Velardi A, Ruggeri L, Moretta A, Moretta L: NK cells: a lesson from mismatched hematopoietic transplantation. Trends Immunol. 23(9), 438-444 (2002).
    • (2002) Trends Immunol. , vol.23 , Issue.9 , pp. 438-444
    • Velardi, A.1    Ruggeri, L.2    Moretta, A.3    Moretta, L.4
  • 45
    • 0037313360 scopus 로고    scopus 로고
    • Alloreactive killer cells: Hindrance and help for haematopoietic transplants
    • Parham P, McQueen KL: Alloreactive killer cells: hindrance and help for haematopoietic transplants. Nat. Rev. Immunol. 3(2), 108-122 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , Issue.2 , pp. 108-122
    • Parham, P.1    McQueen, K.L.2
  • 46
    • 30344461633 scopus 로고    scopus 로고
    • Pathophysiology of graft-versus-host disease
    • Ferrara JL, Reddy P: Pathophysiology of graft-versus-host disease. Semin. Hematol. 43(1), 3-10 (2006).
    • (2006) Semin. Hematol. , vol.43 , Issue.1 , pp. 3-10
    • Ferrara, J.L.1    Reddy, P.2
  • 47
    • 0036838788 scopus 로고    scopus 로고
    • Cytokines, viruses, and graft-versus-host disease
    • Holler E: Cytokines, viruses, and graft-versus-host disease. Curr. Opin. Hematol. 9(6), 479-484 (2002).
    • (2002) Curr. Opin. Hematol. , vol.9 , Issue.6 , pp. 479-484
    • Holler, E.1
  • 48
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger P: The danger model: a renewed sense of self. Science 296(5566), 301-305 (2002).
    • (2002) Science , vol.296 , Issue.5566 , pp. 301-305
    • Matzinger, P.1
  • 49
    • 0035100518 scopus 로고    scopus 로고
    • Acute graft-vs-host disease: Pathobiology and management
    • Goker H, Haznedaroglu IC, Chao NJ: Acute graft-vs-host disease: pathobiology and management. Exp. Hematol. 29(3), 259-277 (2001).
    • (2001) Exp. Hematol. , vol.29 , Issue.3 , pp. 259-277
    • Goker, H.1    Haznedaroglu, I.C.2    Chao, N.J.3
  • 51
    • 75749125362 scopus 로고    scopus 로고
    • Immunomonitoring of graft-versus-host minor histocompatibility antigen correlates with graft-versus-host disease and absence of relapse after graft
    • Laurin D, Hannani D, Pernollet M et al.: Immunomonitoring of graft-versus-host minor histocompatibility antigen correlates with graft-versus-host disease and absence of relapse after graft. Transfusion 50(2), 418-428 (2010).
    • (2010) Transfusion , vol.50 , Issue.2 , pp. 418-428
    • Laurin, D.1    Hannani, D.2    Pernollet, M.3
  • 52
    • 0032879915 scopus 로고    scopus 로고
    • Suicide gene-mediated modulation of graft-versus-host disease
    • Cohen JL, Boyer O, Thomas-Vaslin V, Klatzmann D: Suicide gene-mediated modulation of graft-versus-host disease. Leuk. Lymphoma 34(5-6), 473-480 (1999).
    • (1999) Leuk. Lymphoma , vol.34 , Issue.5-6 , pp. 473-480
    • Cohen, J.L.1    Boyer, O.2    Thomas-Vaslin, V.3    Klatzmann, D.4
  • 54
    • 0030919862 scopus 로고    scopus 로고
    • Prevention of graft-versus-host disease in mice using a suicide gene expressed in T lymphocytes
    • Cohen JL, Boyer O, Salomon B et al.: Prevention of graft-versus-host disease in mice using a suicide gene expressed in T lymphocytes. Blood 89(12), 4636-4645 (1997).
    • (1997) Blood , vol.89 , Issue.12 , pp. 4636-4645
    • Cohen, J.L.1    Boyer, O.2    Salomon, B.3
  • 55
    • 0031154829 scopus 로고    scopus 로고
    • Inhibition of graft-versus-host disease. Use of a T cell-controlled suicide gene
    • Helene M, Lake-Bullock V, Bryson JS, Jennings CD, Kaplan AM: Inhibition of graft-versus-host disease. Use of a T cell-controlled suicide gene. J. Immunol. 158(11), 5079-5082 (1997).
    • (1997) J. Immunol. , vol.158 , Issue.11 , pp. 5079-5082
    • Helene, M.1    Lake-Bullock, V.2    Bryson, J.S.3    Jennings, C.D.4    Kaplan, A.M.5
  • 57
    • 16944365744 scopus 로고    scopus 로고
    • Use of donor T-lymphocytes expressing herpes-simplex thymidine kinase in allogeneic bone marrow transplantation: A Phase I-II study
    • Tiberghien P, Cahn JY, Brion A et al.: Use of donor T-lymphocytes expressing herpes-simplex thymidine kinase in allogeneic bone marrow transplantation: a Phase I-II study. Hum. Gene Ther. 8(5), 615-624 (1997).
    • (1997) Hum. Gene Ther. , vol.8 , Issue.5 , pp. 615-624
    • Tiberghien, P.1    Cahn, J.Y.2    Brion, A.3
  • 58
    • 8644237493 scopus 로고    scopus 로고
    • +-enriched blood stem cells
    • Fehse B, Ayuk FA, Kroger N et al.: Evidence for increased risk of secondary graft failure after in vivo depletion of suicide gene-modified T lymphocytes transplanted in conjunction with CD34+-enriched blood stem cells. Blood 104(10), 3408-3409 (2004).
    • (2004) Blood , vol.104 , Issue.10 , pp. 3408-3409
    • Fehse, B.1    Ayuk, F.A.2    Kroger, N.3
  • 59
    • 0035729970 scopus 로고    scopus 로고
    • Use of suicide gene-expressing donor T-cells to control alloreactivity after haematopoietic stem cell transplantation
    • Tiberghien P: Use of suicide gene-expressing donor T-cells to control alloreactivity after haematopoietic stem cell transplantation. J. Intern. Med. 249(4), 369-377 (2001).
    • (2001) J. Intern. Med. , vol.249 , Issue.4 , pp. 369-377
    • Tiberghien, P.1
  • 60
    • 0030925301 scopus 로고    scopus 로고
    • Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: Harnessing graft-versus-leukemia without myeloablative therapy
    • Giralt S, Estey E, Albitar M et al.: Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: harnessing graft-versus-leukemia without myeloablative therapy. Blood 89(12), 4531-4536 (1997).
    • (1997) Blood , vol.89 , Issue.12 , pp. 4531-4536
    • Giralt, S.1    Estey, E.2    Albitar, M.3
  • 61
    • 67649120068 scopus 로고    scopus 로고
    • Novel application of lentiviral vectors towards treatment of graft-versus-host disease
    • Scaife MD, Neschadim A, Fowler DH, Medin JA: Novel application of lentiviral vectors towards treatment of graft-versus-host disease. Expert Opin. Biol. Ther. 9(6), 749-761 (2009).
    • (2009) Expert Opin. Biol. Ther. , vol.9 , Issue.6 , pp. 749-761
    • Scaife, M.D.1    Neschadim, A.2    Fowler, D.H.3    Medin, J.A.4
  • 62
    • 60849098427 scopus 로고    scopus 로고
    • Il-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes
    • Kaneko S, Mastaglio S, Bondanza A et al.: Il-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes. Blood 113(5), 1006-1015 (2009).
    • (2009) Blood , vol.113 , Issue.5 , pp. 1006-1015
    • Kaneko, S.1    Mastaglio, S.2    Bondanza, A.3
  • 63
    • 21044431642 scopus 로고    scopus 로고
    • Improving the ex vivo retroviral-mediated suicide-gene transfer process in T lymphocytes to preserve immune function
    • Robinet E, Fehse B, Ebeling S, Sauce D, Ferrand C, Tiberghien P: Improving the ex vivo retroviral-mediated suicide-gene transfer process in T lymphocytes to preserve immune function. Cytotherapy 7(2), 150-157 (2005).
    • (2005) Cytotherapy , vol.7 , Issue.2 , pp. 150-157
    • Robinet, E.1    Fehse, B.2    Ebeling, S.3    Sauce, D.4    Ferrand, C.5    Tiberghien, P.6
  • 64
    • 0037441766 scopus 로고    scopus 로고
    • Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell-depleted stem cell transplantation
    • Marktel S, Magnani Z, Ciceri F et al.: Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell-depleted stem cell transplantation. Blood 101(4), 1290-1298 (2003).
    • (2003) Blood , vol.101 , Issue.4 , pp. 1290-1298
    • Marktel, S.1    Magnani, Z.2    Ciceri, F.3
  • 65
    • 0037438666 scopus 로고    scopus 로고
    • CD28 costimulation and immunoaffinity-based selection efficiently generate primary gene-modified T cells for adoptive immunotherapy
    • Berger C, Blau CA, Clackson T, Riddell SR, Heimfeld S: CD28 costimulation and immunoaffinity-based selection efficiently generate primary gene-modified T cells for adoptive immunotherapy. Blood 101(2), 476-484 (2003).
    • (2003) Blood , vol.101 , Issue.2 , pp. 476-484
    • Berger, C.1    Blau, C.A.2    Clackson, T.3    Riddell, S.R.4    Heimfeld, S.5
  • 66
    • 0036966191 scopus 로고    scopus 로고
    • Influence of Ex vivo expansion and retrovirus-mediated gene transfer on primary T lymphocyte phenotype and functions
    • Sauce D, Tonnelier N, Duperrier A et al.: Influence of Ex vivo expansion and retrovirus-mediated gene transfer on primary T lymphocyte phenotype and functions. J. Hematother. Stem Cell Res. 11(6), 929-940 (2002).
    • (2002) J. Hematother. Stem Cell Res. , vol.11 , Issue.6 , pp. 929-940
    • Sauce, D.1    Tonnelier, N.2    Duperrier, A.3
  • 67
    • 0036226792 scopus 로고    scopus 로고
    • Highly efficient retroviral gene transfer based on centrifugation- mediated vector preloading of tissue culture vessels
    • Kuhlcke K, Fehse B, Schilz A et al.: Highly efficient retroviral gene transfer based on centrifugation-mediated vector preloading of tissue culture vessels. Mol. Ther. 5(4), 473-478 (2002).
    • (2002) Mol. Ther. , vol.5 , Issue.4 , pp. 473-478
    • Kuhlcke, K.1    Fehse, B.2    Schilz, A.3
  • 68
    • 0037085323 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer in primary T lymphocytes impairs their anti-Epstein- Barr virus potential through both culture-dependent and selection process-dependent mechanisms
    • Sauce D, Bodinier M, Garin M et al.: Retrovirus-mediated gene transfer in primary T lymphocytes impairs their anti-Epstein- Barr virus potential through both culture-dependent and selection process-dependent mechanisms. Blood 99(4), 1165-1173 (2002).
    • (2002) Blood , vol.99 , Issue.4 , pp. 1165-1173
    • Sauce, D.1    Bodinier, M.2    Garin, M.3
  • 69
    • 0034690616 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer in primary T lymphocytes: Influence of the transduction/selection process and of ex vivo expansion on the T cell receptor b chain hypervariable region repertoire
    • Ferrand C, Robinet E, Contassot E et al.: Retrovirus-mediated gene transfer in primary T lymphocytes: influence of the transduction/selection process and of ex vivo expansion on the T cell receptor b chain hypervariable region repertoire. Hum. Gene Ther. 11(8), 1151-1164 (2000).
    • (2000) Hum. Gene Ther. , vol.11 , Issue.8 , pp. 1151-1164
    • Ferrand, C.1    Robinet, E.2    Contassot, E.3
  • 70
    • 0032692396 scopus 로고    scopus 로고
    • Facilitation of retrovirus-mediated gene transfer into hematopoietic stem and progenitor cells and peripheral blood T-lymphocytes utilizing recombinant fibronectin fragments
    • Pollok KE, Williams DA: Facilitation of retrovirus-mediated gene transfer into hematopoietic stem and progenitor cells and peripheral blood T-lymphocytes utilizing recombinant fibronectin fragments. Curr. Opin. Mol. Ther. 1(5), 595-604 (1999).
    • (1999) Curr. Opin. Mol. Ther. , vol.1 , Issue.5 , pp. 595-604
    • Pollok, K.E.1    Williams, D.A.2
  • 71
    • 0032824662 scopus 로고    scopus 로고
    • Establishment of an optimised gene transfer protocol for human primary T lymphocytes according to clinical requirements
    • Ayuk F, Li Z, Kuhlcke K et al.: Establishment of an optimised gene transfer protocol for human primary T lymphocytes according to clinical requirements. Gene Ther. 6(10), 1788-1792 (1999).
    • (1999) Gene Ther. , vol.6 , Issue.10 , pp. 1788-1792
    • Ayuk, F.1    Li, Z.2    Kuhlcke, K.3
  • 72
    • 0032168558 scopus 로고    scopus 로고
    • Ex vivo anti-CD3 antibody-activated donor T cells have a reduced ability to cause lethal murine graft-versus-host disease but retain their ability to facilitate alloengraftment
    • Drobyski WR, Majewski D, Ozker K, Hanson G: Ex vivo anti-CD3 antibody-activated donor T cells have a reduced ability to cause lethal murine graft-versus-host disease but retain their ability to facilitate alloengraftment. J. Immunol. 161(5), 2610-2619 (1998).
    • (1998) J. Immunol. , vol.161 , Issue.5 , pp. 2610-2619
    • Drobyski, W.R.1    Majewski, D.2    Ozker, K.3    Hanson, G.4
  • 74
    • 0029118325 scopus 로고
    • High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes
    • Bunnell BA, Muul LM, Donahue RE, Blaese RM, Morgan RA: High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes. Proc. Natl Acad. Sci. USA 92(17), 7739-7743 (1995).
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , Issue.17 , pp. 7739-7743
    • Bunnell, B.A.1    Muul, L.M.2    Donahue, R.E.3    Blaese, R.M.4    Morgan, R.A.5
  • 75
    • 51349090473 scopus 로고    scopus 로고
    • Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-x1
    • Hacein-Bey-Abina S, Garrigue A, Wang GP et al.: Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-x1. J. Clin. Invest. 118(9), 3132-3142 (2008).
    • (2008) J. Clin. Invest. , vol.118 , Issue.9 , pp. 3132-3142
    • Hacein-Bey-Abina, S.1    Garrigue, A.2    Wang, G.P.3
  • 76
    • 0142084745 scopus 로고    scopus 로고
    • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
    • Hacein-Bey-Abina S, Von Kalle C, Schmidt M et al.: LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302(5644), 415-419 (2003).
    • (2003) Science , vol.302 , Issue.5644 , pp. 415-419
    • Hacein-Bey-Abina, S.1    Von Kalle, C.2    Schmidt, M.3
  • 77
    • 0035704938 scopus 로고    scopus 로고
    • Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes
    • Li CM, Park JH, Simonaro CM et al.: Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes. Genomics 79(2), 218-224 (2002).
    • (2002) Genomics , vol.79 , Issue.2 , pp. 218-224
    • Li, C.M.1    Park, J.H.2    Simonaro, C.M.3
  • 78
    • 0037162715 scopus 로고    scopus 로고
    • HIV-1 integration in the human genome favors active genes and local hotspots
    • Schroder AR, Shinn P, Chen H, Berry C, Ecker JR, Bushman F: HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110(4), 521-529 (2002).
    • (2002) Cell , vol.110 , Issue.4 , pp. 521-529
    • Schroder, A.R.1    Shinn, P.2    Chen, H.3    Berry, C.4    Ecker, J.R.5    Bushman, F.6
  • 79
    • 33745108790 scopus 로고    scopus 로고
    • Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration
    • Montini E, Cesana D, Schmidt M et al.: Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration. Nat. Biotechnol. 24(6), 687-696 (2006).
    • (2006) Nat. Biotechnol. , vol.24 , Issue.6 , pp. 687-696
    • Montini, E.1    Cesana, D.2    Schmidt, M.3
  • 80
    • 65249101260 scopus 로고    scopus 로고
    • The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy
    • Montini E, Cesana D, Schmidt M et al.: The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy. J. Clin. Invest. 119(4), 964-975 (2009).
    • (2009) J. Clin. Invest. , vol.119 , Issue.4 , pp. 964-975
    • Montini, E.1    Cesana, D.2    Schmidt, M.3
  • 81
    • 58149380742 scopus 로고    scopus 로고
    • Stem cell concepts renew cancer research
    • Dick JE: Stem cell concepts renew cancer research. Blood 112(13), 4793-4807 (2008).
    • (2008) Blood , vol.112 , Issue.13 , pp. 4793-4807
    • Dick, J.E.1
  • 82
    • 55249087037 scopus 로고    scopus 로고
    • Resistance of mature T cells to oncogene transformation
    • Newrzela S, Cornils K, Li Z et al.: Resistance of mature T cells to oncogene transformation. Blood 112(6), 2278-2286 (2008).
    • (2008) Blood , vol.112 , Issue.6 , pp. 2278-2286
    • Newrzela, S.1    Cornils, K.2    Li, Z.3
  • 83
    • 33645451483 scopus 로고    scopus 로고
    • Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors
    • Baum C, Kustikova O, Modlich U, Li Z, Fehse B: Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors. Hum. Gene Ther. 17(3), 253-263 (2006).
    • (2006) Hum. Gene Ther. , vol.17 , Issue.3 , pp. 253-263
    • Baum, C.1    Kustikova, O.2    Modlich, U.3    Li, Z.4    Fehse, B.5
  • 84
    • 0030809133 scopus 로고    scopus 로고
    • Potential and limitations of hsv-tk-transduced donor peripheral blood lymphocytes after allo-BMT
    • Bonini C, Bordignon C: Potential and limitations of hsv-tk-transduced donor peripheral blood lymphocytes after allo-BMT. Hematol. Cell Ther 39(5), 273-274 (1997).
    • (1997) Hematol. Cell Ther , vol.39 , Issue.5 , pp. 273-274
    • Bonini, C.1    Bordignon, C.2
  • 85
    • 0035174929 scopus 로고    scopus 로고
    • Molecular mechanism for ganciclovir resistance in human T lymphocytes transduced with retroviral vectors carrying the herpes simplex virus thymidine kinase gene
    • Garin MI, Garrett E, Tiberghien P et al.: Molecular mechanism for ganciclovir resistance in human T lymphocytes transduced with retroviral vectors carrying the herpes simplex virus thymidine kinase gene. Blood 97(1), 122-129 (2001).
    • (2001) Blood , vol.97 , Issue.1 , pp. 122-129
    • Garin, M.I.1    Garrett, E.2    Tiberghien, P.3
  • 86
    • 17944370860 scopus 로고    scopus 로고
    • Elimination of the truncated message from the herpes simplex virus thymidine kinase suicide gene
    • Chalmers D, Ferrand C, Apperley JF et al.: Elimination of the truncated message from the herpes simplex virus thymidine kinase suicide gene. Mol. Ther. 4(2), 146-148 (2001).
    • (2001) Mol. Ther. , vol.4 , Issue.2 , pp. 146-148
    • Chalmers, D.1    Ferrand, C.2    Apperley, J.F.3
  • 87
    • 0037192631 scopus 로고    scopus 로고
    • Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: Critical role of DNA breaks, BCL-2 decline and caspase-9 activation
    • Tomicic MT, Thust R, Kaina B: Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: critical role of DNA breaks, BCL-2 decline and caspase-9 activation. Oncogene 21(14), 2141-2153 (2002).
    • (2002) Oncogene , vol.21 , Issue.14 , pp. 2141-2153
    • Tomicic, M.T.1    Thust, R.2    Kaina, B.3
  • 88
    • 0037064092 scopus 로고    scopus 로고
    • Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing
    • Adachi M, Sampath J, Lan LB et al.: Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing. J. Biol. Chem. 277(41), 38998-39004 (2002).
    • (2002) J. Biol. Chem. , vol.277 , Issue.41 , pp. 38998-39004
    • Adachi, M.1    Sampath, J.2    Lan, L.B.3
  • 89
    • 13344261952 scopus 로고    scopus 로고
    • T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients
    • Riddell SR, Elliott M, Lewinsohn DA et al.: T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients. Nat. Med. 2(2), 216-223 (1996).
    • (1996) Nat. Med. , vol.2 , Issue.2 , pp. 216-223
    • Riddell, S.R.1    Elliott, M.2    Lewinsohn, D.A.3
  • 90
    • 0035312983 scopus 로고    scopus 로고
    • + hematopoietic cells
    • Rosenzweig M, Connole M, Glickman R et al.: Induction of cytotoxic T lymphocyte and antibody responses to enhanced green fluorescent protein following transplantation of transduced CD34+ hematopoietic cells. Blood 97(7), 1951-1959 (2001).
    • (2001) Blood , vol.97 , Issue.7 , pp. 1951-1959
    • Rosenzweig, M.1    Connole, M.2    Glickman, R.3
  • 91
    • 0032505705 scopus 로고    scopus 로고
    • Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors
    • Verzeletti S, Bonini C, Marktel S et al.: Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: clinical follow-up and improved new vectors. Hum. Gene Ther. 9(15), 2243-2251 (1998).
    • (1998) Hum. Gene Ther. , vol.9 , Issue.15 , pp. 2243-2251
    • Verzeletti, S.1    Bonini, C.2    Marktel, S.3
  • 92
    • 0033559722 scopus 로고    scopus 로고
    • Genetically corrected autologous stem cells engraft, but host immune responses limit their utility in canine a-l-iduronidase deficiency
    • Lutzko C, Kruth S, Abrams-Ogg AC et al.: Genetically corrected autologous stem cells engraft, but host immune responses limit their utility in canine a-l-iduronidase deficiency. Blood 93(6), 1895-1905 (1999).
    • (1999) Blood , vol.93 , Issue.6 , pp. 1895-1905
    • Lutzko, C.1    Kruth, S.2    Abrams-Ogg, A.C.3
  • 93
    • 33644750264 scopus 로고    scopus 로고
    • Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-tk-modified donor T cells after allogeneic hematopoietic cell transplantation
    • Berger C, Flowers ME, Warren EH, Riddell SR: Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-tk-modified donor T cells after allogeneic hematopoietic cell transplantation. Blood 107(6), 2294-2302 (2006).
    • (2006) Blood , vol.107 , Issue.6 , pp. 2294-2302
    • Berger, C.1    Flowers, M.E.2    Warren, E.H.3    Riddell, S.R.4
  • 94
    • 34249748406 scopus 로고    scopus 로고
    • The potential immunogenicity of the tk suicide gene does not prevent full clinical benefit associated with the use of tk-transduced donor lymphocytes in HSCT for hematologic malignancies
    • Traversari C, Marktel S, Magnani Z et al.: The potential immunogenicity of the tk suicide gene does not prevent full clinical benefit associated with the use of tk-transduced donor lymphocytes in HSCT for hematologic malignancies. Blood 109(11), 4708-4715 (2007).
    • (2007) Blood , vol.109 , Issue.11 , pp. 4708-4715
    • Traversari, C.1    Marktel, S.2    Magnani, Z.3
  • 95
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer and expression
    • 984-986, 989-990
    • Miller AD, Rosman GJ: Improved retroviral vectors for gene transfer and expression. Biotechniques 7(9), 980-982, 984-986, 989-990 (1989).
    • (1989) Biotechniques , vol.7 , Issue.9 , pp. 980-982
    • Miller, A.D.1    Rosman, G.J.2
  • 96
    • 0029052483 scopus 로고
    • Efficient expression of functional human mdr1 gene in murine bone marrow after retroviral transduction of purified hematopoietic stem cells
    • Licht T, Aksentijevich I, Gottesman MM, Pastan I: Efficient expression of functional human mdr1 gene in murine bone marrow after retroviral transduction of purified hematopoietic stem cells. Blood 86(1), 111-121 (1995).
    • (1995) Blood , vol.86 , Issue.1 , pp. 111-121
    • Licht, T.1    Aksentijevich, I.2    Gottesman, M.M.3    Pastan, I.4
  • 97
    • 0023989715 scopus 로고
    • Fluorescence-activated cell analysis and sorting of viable mammalian cells based on b-d-galactosidase activity after transduction of E. coli lacz
    • Nolan GP, Fiering S, Nicolas JF, Herzenberg LA: Fluorescence-activated cell analysis and sorting of viable mammalian cells based on b-d-galactosidase activity after transduction of E. coli lacz. Proc. Natl Acad. Sci. USA 85(8), 2603-2607 (1988).
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , Issue.8 , pp. 2603-2607
    • Nolan, G.P.1    Fiering, S.2    Nicolas, J.F.3    Herzenberg, L.A.4
  • 98
    • 0028220643 scopus 로고
    • Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer
    • Mavilio F, Ferrari G, Rossini S et al.: Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer. Blood 83(7), 1988-1997 (1994).
    • (1994) Blood , vol.83 , Issue.7 , pp. 1988-1997
    • Mavilio, F.1    Ferrari, G.2    Rossini, S.3
  • 99
    • 0028143406 scopus 로고
    • Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer
    • Pawliuk R, Kay R, Lansdorp P, Humphries RK: Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer. Blood 84(9), 2868-2877 (1994).
    • (1994) Blood , vol.84 , Issue.9 , pp. 2868-2877
    • Pawliuk, R.1    Kay, R.2    Lansdorp, P.3    Humphries, R.K.4
  • 100
    • 0029101613 scopus 로고
    • A new reporter system for detection of retroviral infection
    • Planelles V, Haislip A, Withers-Ward ES et al.: A new reporter system for detection of retroviral infection. Gene Ther. 2(6), 369-376 (1995).
    • (1995) Gene Ther. , vol.2 , Issue.6 , pp. 369-376
    • Planelles, V.1    Haislip, A.2    Withers-Ward, E.S.3
  • 101
    • 0034182866 scopus 로고    scopus 로고
    • CD34 splice variant: An attractive marker for selection of gene-modified cells
    • Fehse B, Richters A, Putimtseva-Scharf K et al.: CD34 splice variant: an attractive marker for selection of gene-modified cells. Mol. Ther. 1(5 Pt 1), 448-456 (2000).
    • (2000) Mol. Ther. , vol.1 , Issue.5 PART 1 , pp. 448-456
    • Fehse, B.1    Richters, A.2    Putimtseva-Scharf, K.3
  • 102
    • 0037134031 scopus 로고    scopus 로고
    • Murine leukemia induced by retroviral gene marking
    • Li Z, Dullmann J, Schiedlmeier B et al.: Murine leukemia induced by retroviral gene marking. Science 296(5567), 497 (2002).
    • (2002) Science , vol.296 , Issue.5567 , pp. 497
    • Li, Z.1    Dullmann, J.2    Schiedlmeier, B.3
  • 103
    • 0344511772 scopus 로고    scopus 로고
    • Safety of retroviral gene marking with a truncated NGF receptor
    • Bonini C, Grez M, Traversari C et al.: Safety of retroviral gene marking with a truncated NGF receptor. Nat Med 9(4), 367-369 (2003).
    • (2003) Nat Med , vol.9 , Issue.4 , pp. 367-369
    • Bonini, C.1    Grez, M.2    Traversari, C.3
  • 104
    • 61849170020 scopus 로고    scopus 로고
    • High-affinity neurotrophin receptors and ligands promote leukemogenesis
    • Li Z, Beutel G, Rhein M et al.: High-affinity neurotrophin receptors and ligands promote leukemogenesis. Blood 113(9), 2028-2037 (2009).
    • (2009) Blood , vol.113 , Issue.9 , pp. 2028-2037
    • Li, Z.1    Beutel, G.2    Rhein, M.3
  • 105
  • 106
    • 35848938959 scopus 로고    scopus 로고
    • Ouaselect, a novel ouabain-resistant human marker gene that allows efficient cell selection within 48 h
    • Treschow A, Unger C, Aints A, Felldin U, Aschan J, Dilber MS: Ouaselect, a novel ouabain-resistant human marker gene that allows efficient cell selection within 48 h. Gene Ther. 14(22), 1564-1572 (2007).
    • (2007) Gene Ther. , vol.14 , Issue.22 , pp. 1564-1572
    • Treschow, A.1    Unger, C.2    Aints, A.3    Felldin, U.4    Aschan, J.5    Dilber, M.S.6
  • 108
    • 0027182862 scopus 로고
    • The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT)
    • Knox RJ, Friedlos F, Boland MP: The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT). Cancer Metastasis Rev. 12, 195-212 (1993).
    • (1993) Cancer Metastasis Rev. , vol.12 , pp. 195-212
    • Knox, R.J.1    Friedlos, F.2    Boland, M.P.3
  • 109
    • 2442696806 scopus 로고    scopus 로고
    • Virus-directed enzyme prodrug therapy: Intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer
    • Palmer DH, Mautner V, Mirza D et al.: Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer. J. Clin. Oncol. 22, 1546-1552 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , pp. 1546-1552
    • Palmer, D.H.1    Mautner, V.2    Mirza, D.3
  • 110
    • 0028065106 scopus 로고
    • Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene
    • Wei MX, Tamiya T, Chase M et al.: Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene. Hum. Gene Ther. 5, 969-978 (1994).
    • (1994) Hum. Gene Ther. , vol.5 , pp. 969-978
    • Wei, M.X.1    Tamiya, T.2    Chase, M.3
  • 111
    • 0003374533 scopus 로고    scopus 로고
    • Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma: A Phase I/II study
    • Lohr M, Bago ZT, Bergmeister H et al.: Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma: a Phase I/II study. J. Mol. Med. 77, 393-398 (1999).
    • (1999) J. Mol. Med. , vol.77 , pp. 393-398
    • Lohr, M.1    Bago, Z.T.2    Bergmeister, H.3
  • 112
    • 0037255792 scopus 로고    scopus 로고
    • Treatment of inoperable pancreatic carcinoma using a cell-based local chemotherapy: Results of a Phase I/II clinical trial
    • Salmons B, Lohr M, Gunzburg WH: Treatment of inoperable pancreatic carcinoma using a cell-based local chemotherapy: results of a Phase I/II clinical trial. J. Gastroenterol. 38(Suppl. 15), 78-84 (2003).
    • (2003) J. Gastroenterol. , vol.38 , Issue.SUPPL. 15 , pp. 78-84
    • Salmons, B.1    Lohr, M.2    Gunzburg, W.H.3
  • 113
    • 19344365874 scopus 로고    scopus 로고
    • An inducible caspase 9 safety switch for T-cell therapy
    • Straathof KC, Pule MA, Yotnda P et al.: An inducible caspase 9 safety switch for T-cell therapy. Blood 105, 4247-4254 (2005).
    • (2005) Blood , vol.105 , pp. 4247-4254
    • Straathof, K.C.1    Pule, M.A.2    Yotnda, P.3
  • 114
    • 34447310075 scopus 로고    scopus 로고
    • Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation
    • Tey SK, Dotti G, Rooney CM, Heslop HE, Brenner MK: Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation. Biol. Blood Marrow Transplant. 13, 913-924 (2007).
    • (2007) Biol. Blood Marrow Transplant. , vol.13 , pp. 913-924
    • Tey, S.K.1    Dotti, G.2    Rooney, C.M.3    Heslop, H.E.4    Brenner, M.K.5
  • 115
    • 0034054579 scopus 로고    scopus 로고
    • Genetic modification of human T cells with CD20: A strategy to purify and lyse transduced cells with anti-CD20 antibodies
    • Introna M, Barbui AM, Bambacioni F et al.: Genetic modification of human T cells with CD20: a strategy to purify and lyse transduced cells with anti-CD20 antibodies. Hum. Gene Ther. 11, 611-620 (2000).
    • (2000) Hum. Gene Ther. , vol.11 , pp. 611-620
    • Introna, M.1    Barbui, A.M.2    Bambacioni, F.3
  • 116
    • 50549096284 scopus 로고    scopus 로고
    • Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20- specific T cells
    • Till BG, Jensen MC, Wang J et al.: Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20- specific T cells. Blood 112, 2261-2271 (2008).
    • (2008) Blood , vol.112 , pp. 2261-2271
    • Till, B.G.1    Jensen, M.C.2    Wang, J.3
  • 117
    • 34247194881 scopus 로고    scopus 로고
    • Engineered human TMPK/AZT as a novel enzyme/ prodrug axis for suicide gene therapy
    • Sato T, Neschadim A, Konrad M, Fowler DH, Lavie A, Medin JA: Engineered human TMPK/AZT as a novel enzyme/ prodrug axis for suicide gene therapy. Mol. Ther. 15, 962-970 (2007).
    • (2007) Mol. Ther. , vol.15 , pp. 962-970
    • Sato, T.1    Neschadim, A.2    Konrad, M.3    Fowler, D.H.4    Lavie, A.5    Medin, J.A.6
  • 118
    • 0035282726 scopus 로고    scopus 로고
    • A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease
    • Thomis DC, Marktel S, Bonini C et al.: A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease. Blood 97, 1249-1257 (2001).
    • Blood , vol.97 , Issue.1249-1257 , pp. 2001
    • Thomis, D.C.1    Marktel, S.2    Bonini, C.3
  • 119
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
    • Moolten FL: Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res. 46, 5276-5281 (1986).
    • (1986) Cancer Res. , vol.46 , pp. 5276-5281
    • Moolten, F.L.1
  • 120
    • 0028795530 scopus 로고
    • Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation
    • Bordignon C, Bonini C, Verzeletti S et al.: Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation. Hum. Gene Ther. 6, 813-819 (1995).
    • (1995) Hum. Gene Ther. , vol.6 , pp. 813-819
    • Bordignon, C.1    Bonini, C.2    Verzeletti, S.3
  • 121
    • 0030809133 scopus 로고    scopus 로고
    • Potential and limitations of HSV-tk-transduced donor peripheral blood lymphocytes after allo-BMT
    • Bonini C, Bordignon C: Potential and limitations of HSV-tk-transduced donor peripheral blood lymphocytes after allo-BMT. Hematol. Cell Ther 39, 273-274 (1997).
    • (1997) Hematol. Cell Ther , vol.39 , pp. 273-274
    • Bonini, C.1    Bordignon, C.2
  • 122
    • 0035729970 scopus 로고    scopus 로고
    • Use of suicide gene-expressing donor T-cells to control alloreactivity after haematopoietic stem cell transplantation
    • Tiberghien P: Use of suicide gene-expressing donor T-cells to control alloreactivity after haematopoietic stem cell transplantation. J. Intern. Med. 249, 369-377 (2001).
    • (2001) J. Intern. Med. , vol.249 , pp. 369-377
    • Tiberghien, P.1
  • 123
    • 0141596016 scopus 로고    scopus 로고
    • Herpes simplex thymidine kinase gene-transduced donor lymphocyte infusions
    • Burt RK, Drobyski WR, Seregina T et al.: Herpes simplex thymidine kinase gene-transduced donor lymphocyte infusions. Exp. Hematol. 31, 903-910 (2003).
    • (2003) Exp. Hematol. , vol.31 , pp. 903-910
    • Burt, R.K.1    Drobyski, W.R.2    Seregina, T.3
  • 124
    • 8644237493 scopus 로고    scopus 로고
    • +-enriched blood stem cells
    • Fehse B, Ayuk FA, Kroger N et al.: Evidence for increased risk of secondary graft failure after in vivo depletion of suicide gene-modified T lymphocytes transplanted in conjunction with CD34+-enriched blood stem cells. Blood 104, 3408-3409 (2004).
    • (2004) Blood , vol.104 , pp. 3408-3409
    • Fehse, B.1    Ayuk, F.A.2    Kroger, N.3
  • 125
    • 34249688206 scopus 로고    scopus 로고
    • Antitumor effects of HSV-tk-engineered donor lymphocytes after allogeneic stem-cell transplantation
    • Ciceri F, Bonini C, Marktel S et al.: Antitumor effects of HSV-tk-engineered donor lymphocytes after allogeneic stem-cell transplantation. Blood 109, 4698-4707 (2007).
    • (2007) Blood , vol.109 , pp. 4698-4707
    • Ciceri, F.1    Bonini, C.2    Marktel, S.3
  • 126
    • 65349157330 scopus 로고    scopus 로고
    • Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): A non-randomised Phase I-II study
    • Ciceri F, Bonini C, Stanghellini MT et al.: Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised Phase I-II study. Lancet Oncol. 10, 489-500 (2009).
    • (2009) Lancet Oncol. , vol.10 , pp. 489-500
    • Ciceri, F.1    Bonini, C.2    Stanghellini, M.T.3
  • 127
    • 0026599586 scopus 로고
    • Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system
    • Mullen CA, Kilstrup M, Blaese RM: Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system. Proc. Natl Acad. Sci. USA 89, 33-37 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 33-37
    • Mullen, C.A.1    Kilstrup, M.2    Blaese, R.M.3
  • 128
    • 16944365155 scopus 로고    scopus 로고
    • Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine
    • Crystal RG, Hirschowitz E, Lieberman M et al.: Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine. Hum. Gene Ther. 8, 985-1001 (1997).
    • (1997) Hum. Gene Ther. , vol.8 , pp. 985-1001
    • Crystal, R.G.1    Hirschowitz, E.2    Lieberman, M.3
  • 129
    • 0035839429 scopus 로고    scopus 로고
    • A Phase i trial of genetically modified Salmonella typhimurium expressing cytosine deaminase (TAPET-CD, VNP20029) administered by intratumoral injection in combination with 5-fluorocytosine for patients with advanced or metastatic cancer. Protocol no: CL-017. Version: April 9
    • Cunningham C, Nemunaitis J: A Phase I trial of genetically modified Salmonella typhimurium expressing cytosine deaminase (TAPET-CD, VNP20029) administered by intratumoral injection in combination with 5-fluorocytosine for patients with advanced or metastatic cancer. Protocol no: CL-017. Version: April 9, 2001. Hum. Gene Ther. 12, 1594-1596 (2001).
    • (2001) Hum. Gene Ther. , vol.12 , Issue.1594-1596 , pp. 2001
    • Cunningham, C.1    Nemunaitis, J.2
  • 130
    • 0036733759 scopus 로고    scopus 로고
    • Phase i study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer
    • Freytag SO, Khil M, Stricker H et al.: Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer. Cancer Res. 62, 4968-4976 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 4968-4976
    • Freytag, S.O.1    Khil, M.2    Stricker, H.3
  • 131
    • 12444302834 scopus 로고    scopus 로고
    • Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients
    • Nemunaitis, J, Cunningham C, Senzer N et al.: Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients. Cancer Gene Ther. 10, 737-744 (2003).
    • (2003) Cancer Gene Ther. , vol.10 , pp. 737-744
    • Nemunaitis, J.1    Cunningham, C.2    Senzer, N.3
  • 132
    • 0019123758 scopus 로고
    • Expression of a bacterial gene in mammalian cells
    • Mulligan RC, Berg P: Expression of a bacterial gene in mammalian cells. Science 209, 1422-1427 (1980).
    • (1980) Science , vol.209 , pp. 1422-1427
    • Mulligan, R.C.1    Berg, P.2
  • 133
    • 0028465423 scopus 로고
    • Tumor cell bystander killing in colonic carcinoma utilizing the E. coli deoD gene to generate toxic purines
    • Sorscher EJ, Peng S, Bebok Z, Allan PW, Bennett LL Jr, Parker WB: Tumor cell bystander killing in colonic carcinoma utilizing the E. coli deoD gene to generate toxic purines. Gene Ther. 1, 233-238 (1994).
    • (1994) Gene Ther. , vol.1 , pp. 233-238
    • Sorscher, E.J.1    Peng, S.2    Bebok, Z.3    Allan, P.W.4    Bennett Jr., L.L.5    Parker, W.B.6
  • 137
    • 84960948722 scopus 로고
    • Treatment of murine leukaemia with X rays and homologous bone marrow; Preliminary communication
    • Barnes DW, Corp MJ, Loutit JF, Neal FE: Treatment of murine leukaemia with X rays and homologous bone marrow; preliminary communication. Br. Med. J. 2(4993), 626-627 (1956).
    • (1956) Br. Med. J. , vol.2 , Issue.4993 , pp. 626-627
    • Barnes, D.W.1    Corp, M.J.2    Loutit, J.F.3    Neal, F.E.4
  • 138
    • 36949092433 scopus 로고
    • Avoidance of secondary disease in radiation chimaeras
    • Barnes DW, Ilbery PL, Loutit JF: Avoidance of secondary disease in radiation chimaeras. Nature 181(4607), 488 (1958)
    • (1958) Nature , vol.181 , Issue.4607 , pp. 488
    • Barnes, D.W.1    Ilbery, P.L.2    Loutit, J.F.3
  • 139
    • 0014195841 scopus 로고
    • Activity of lymphoid tissues from antilymphocyte-serum-treated mice
    • Boak JL, Fox M, Wilson RE: Activity of lymphoid tissues from antilymphocyte-serum-treated mice. Lancet 1(7493), 750-752 (1967).
    • (1967) Lancet , vol.1 , Issue.7493 , pp. 750-752
    • Boak, J.L.1    Fox, M.2    Wilson, R.E.3
  • 140
    • 0015894796 scopus 로고
    • Graft versus leukemia. 3. Apparent independent anthost and antileukemia activity of transplanted immunocompetent cells
    • Bortin MM, Rimm AA, Saltzstein EC, Rodey GE: Graft versus leukemia. 3. Apparent independent anthost and antileukemia activity of transplanted immunocompetent cells. Transplantation 16(3), 182-188 (1973).
    • (1973) Transplantation , vol.16 , Issue.3 , pp. 182-188
    • Bortin, M.M.1    Rimm, A.A.2    Saltzstein, E.C.3    Rodey, G.E.4
  • 141
    • 0018697639 scopus 로고
    • Graft-versus-leukaemia reactivity induced by alloimmunisation without augmentation of graft-versus-host reactivity
    • Bortin MM, Truitt RL, Rimm AA, Bach FH: Graft-versus-leukaemia reactivity induced by alloimmunisation without augmentation of graft-versus-host reactivity. Nature 281(5731), 490-491 (1979).
    • (1979) Nature , vol.281 , Issue.5731 , pp. 490-491
    • Bortin, M.M.1    Truitt, R.L.2    Rimm, A.A.3    Bach, F.H.4
  • 142
    • 0014221544 scopus 로고
    • Immunological reactivity of lymphoid cells after treatment with anti-lymphocytic serum
    • Brent L, Courtenay T, Gowland G: Immunological reactivity of lymphoid cells after treatment with anti-lymphocytic serum. Nature 215(5109), 1461-1464 (1967).
    • (1967) Nature , vol.215 , Issue.5109 , pp. 1461-1464
    • Brent, L.1    Courtenay, T.2    Gowland, G.3
  • 143
    • 29844448554 scopus 로고    scopus 로고
    • Can only partial T-cell depletion of the graft before hematopoietic stem cell transplantation mitigate graft-versus-host disease while preserving a graft-versus-leukemia reaction? A prospective Phase II study
    • Chalandon Y, Roosnek E, Mermillod B, Waelchli L, Helg C, Chapuis B: Can only partial T-cell depletion of the graft before hematopoietic stem cell transplantation mitigate graft-versus-host disease while preserving a graft-versus-leukemia reaction? A prospective Phase II study. Biol. Blood Marrow Transplant. 12(1), 102-110 (2006).
    • (2006) Biol. Blood Marrow Transplant. , vol.12 , Issue.1 , pp. 102-110
    • Chalandon, Y.1    Roosnek, E.2    Mermillod, B.3    Waelchli, L.4    Helg, C.5    Chapuis, B.6
  • 144
    • 3242756749 scopus 로고    scopus 로고
    • Tumor necrosis factor-α blockade for the treatment of acute gvhd
    • Couriel D, Saliba R, Hicks K et al.: Tumor necrosis factor-α blockade for the treatment of acute gvhd. Blood 104(3), 649-654 (2004).
    • (2004) Blood , vol.104 , Issue.3 , pp. 649-654
    • Couriel, D.1    Saliba, R.2    Hicks, K.3
  • 145
    • 0029027351 scopus 로고
    • Identification of a graft versus host disease-associated human minor histocompatibility antigen
    • den Haan JM, Sherman NE, Blokland E et al.: Identification of a graft versus host disease-associated human minor histocompatibility antigen. Science 268(5216), 1476-1480 (1995).
    • (1995) Science , vol.268 , Issue.5216 , pp. 1476-1480
    • Den Haan, J.M.1    Sherman, N.E.2    Blokland, E.3
  • 146
    • 0033519661 scopus 로고    scopus 로고
    • Transplantation of anergic histoincompatible bone marrow allografts
    • Guinan EC, Boussiotis VA, Neuberg D et al.: Transplantation of anergic histoincompatible bone marrow allografts. N. Engl. J. Med. 340(22), 1704-1714 (1999).
    • (1999) N. Engl. J. Med. , vol.340 , Issue.22 , pp. 1704-1714
    • Guinan, E.C.1    Boussiotis, V.A.2    Neuberg, D.3
  • 148
    • 0018257740 scopus 로고
    • Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow
    • Korngold R, Sprent J: Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow. J. Exp. Med. 148(6), 1687-1698 (1978).
    • (1978) J. Exp. Med. , vol.148 , Issue.6 , pp. 1687-1698
    • Korngold, R.1    Sprent, J.2
  • 149
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B et al.: Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 363(9419), 1439-1441 (2004).
    • (2004) Lancet , vol.363 , Issue.9419 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 150
    • 41349118744 scopus 로고    scopus 로고
    • Etanercept plus methylprednisolone as initial therapy for acute graft-versus-host disease
    • Levine JE, Paczesny S, Mineishi S et al.: Etanercept plus methylprednisolone as initial therapy for acute graft-versus-host disease. Blood 111(4), 2470-2475 (2008).
    • (2008) Blood , vol.111 , Issue.4 , pp. 2470-2475
    • Levine, J.E.1    Paczesny, S.2    Mineishi, S.3
  • 151
    • 0023719305 scopus 로고
    • Graft failure in patients receiving T cell-depleted HLA-identical allogeneic marrow transplants
    • Martin PJ, Hansen JA, Torok-Storb B et al.: Graft failure in patients receiving T cell-depleted HLA-identical allogeneic marrow transplants. Bone Marrow Transplant. 3(5), 445-456 (1988).
    • (1988) Bone Marrow Transplant. , vol.3 , Issue.5 , pp. 445-456
    • Martin, P.J.1    Hansen, J.A.2    Torok-Storb, B.3
  • 152
    • 43249122409 scopus 로고    scopus 로고
    • A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique
    • Mielke S, Nunes R, Rezvani K et al.: A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique. Blood 111(8), 4392-4402 (2008)
    • (2008) Blood , vol.111 , Issue.8 , pp. 4392-4402
    • Mielke, S.1    Nunes, R.2    Rezvani, K.3
  • 153
    • 0021345180 scopus 로고
    • Depletion of T lymphocytes in donor marrow prevents significant graft-versus-host disease in matched allogeneic leukaemic marrow transplant recipients
    • Prentice HG, Blacklock HA, Janossy G et al.: Depletion of T lymphocytes in donor marrow prevents significant graft-versus-host disease in matched allogeneic leukaemic marrow transplant recipients. Lancet 1(8375), 472-476 (1984).
    • (1984) Lancet , vol.1 , Issue.8375 , pp. 472-476
    • Prentice, H.G.1    Blacklock, H.A.2    Janossy, G.3
  • 154
    • 0019390679 scopus 로고
    • Transplantation for acute leukaemia with HLA-A and B nonidentical parental marrow cells fractionated with soybean agglutinin and sheep red blood cells
    • Reisner Y, Kapoor N, Kirkpatrick D et al.: Transplantation for acute leukaemia with HLA-A and B nonidentical parental marrow cells fractionated with soybean agglutinin and sheep red blood cells. Lancet 2(8242), 327-331 (1981).
    • (1981) Lancet , vol.2 , Issue.8242 , pp. 327-331
    • Reisner, Y.1    Kapoor, N.2    Kirkpatrick, D.3
  • 155
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • Ruggeri L, Capanni M, Urbani E et al.: Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 295(5562), 2097-2100 (2002).
    • (2002) Science , vol.295 , Issue.5562 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3
  • 156
    • 0012391130 scopus 로고    scopus 로고
    • Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
    • Sato K, Yamashita N, Baba M, Matsuyama T: Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood 101(9), 3581-3589 (2003).
    • (2003) Blood , vol.101 , Issue.9 , pp. 3581-3589
    • Sato, K.1    Yamashita, N.2    Baba, M.3    Matsuyama, T.4
  • 157
    • 0022624255 scopus 로고
    • Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia
    • Storb R, Deeg HJ, Whitehead J et al.: Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia. N. Engl. J. Med. 314(12), 729-735 (1986). (Pubitemid 16124386)
    • (1986) New England Journal of Medicine , vol.314 , Issue.12 , pp. 729-735
    • Storb, R.1    Deeg, H.J.2    Whitehead, J.3
  • 158
    • 0014748313 scopus 로고
    • Methotrexate regimens for control of graft-versus-host disease in dogs with allogeneic marrow grafts
    • Storb R, Epstein RB, Graham TC, Thomas ED: Methotrexate regimens for control of graft-versus-host disease in dogs with allogeneic marrow grafts. Transplantation 9(3), 240-246 (1970).
    • (1970) Transplantation , vol.9 , Issue.3 , pp. 240-246
    • Storb, R.1    Epstein, R.B.2    Graham, T.C.3    Thomas, E.D.4
  • 159
    • 0037093217 scopus 로고    scopus 로고
    • +CD25+ immune regulatory cells inhibits graft-versus-host disease lethality
    • +CD25+ immune regulatory cells inhibits graft-versus-host disease lethality. Blood 99(10), 3493-3499 (2002).
    • (2002) Blood , vol.99 , Issue.10 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 160
    • 0015114945 scopus 로고
    • Allogeneic marrow grafting for hematologic malignancy using HL-A matched donor-recipient sibling pairs
    • Thomas ED, Buckner CD, Rudolph RH et al.: Allogeneic marrow grafting for hematologic malignancy using HL-A matched donor-recipient sibling pairs. Blood 38(3), 267-287 (1971).
    • (1971) Blood , vol.38 , Issue.3 , pp. 267-287
    • Thomas, E.D.1    Buckner, C.D.2    Rudolph, R.H.3
  • 161
    • 0001413705 scopus 로고
    • Marrow transplants in lethally irradiated dogs given methotrexate
    • Thomas ED, Collins JA, Herman EC Jr, Ferrebee JW: Marrow transplants in lethally irradiated dogs given methotrexate. Blood 19, 217-228 (1962).
    • (1962) Blood , vol.19 , pp. 217-228
    • Thomas, E.D.1    Collins, J.A.2    Herman Jr., E.C.3    Ferrebee, J.W.4
  • 163
    • 0000473485 scopus 로고
    • Genetic factors influencing irradiation protection by bone marrow. I. The F1 hybrid effect
    • Uphoff DE: Genetic factors influencing irradiation protection by bone marrow. I. The F1 hybrid effect. J. Natl Cancer Inst. 19(1), 123-130 (1957).
    • (1957) J. Natl Cancer Inst. , vol.19 , Issue.1 , pp. 123-130
    • Uphoff, D.E.1
  • 164
    • 0000061031 scopus 로고
    • Alteration of homograft reaction by A-methopterin in lethally irradiated mice treated with homologous marrow
    • Uphoff DE: Alteration of homograft reaction by A-methopterin in lethally irradiated mice treated with homologous marrow. Proc. Soc. Exp. Biol. Med. 99(3), 651-653 (1958).
    • (1958) Proc. Soc. Exp. Biol. Med. , vol.99 , Issue.3 , pp. 651-653
    • Uphoff, D.E.1
  • 165
    • 0030964190 scopus 로고    scopus 로고
    • + selected cells from peripheral blood
    • Urbano-Ispizua A, Rozman C, Martinez C et al.: Rapid engraftment without significant graft-versus-host disease after allogeneic transplantation of CD34+ selected cells from peripheral blood. Blood 89(11), 3967-3973 (1997).
    • (1997) Blood , vol.89 , Issue.11 , pp. 3967-3973
    • Urbano-Ispizua, A.1    Rozman, C.2    Martinez, C.3
  • 166
    • 0018764352 scopus 로고
    • Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts
    • Weiden PL, Flournoy N, Thomas ED et al.: Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts. N. Engl. J. Med. 300(19), 1068-1073 (1979).
    • (1979) N. Engl. J. Med. , vol.300 , Issue.19 , pp. 1068-1073
    • Weiden, P.L.1    Flournoy, N.2    Thomas, E.D.3
  • 167
    • 0033526011 scopus 로고    scopus 로고
    • + T cells reciprocally regulate acute graft versus host disease
    • + T cells reciprocally regulate acute graft versus host disease. J. Exp. Med. 189(7), 1073-1081 (1999).
    • (1999) J. Exp. Med. , vol.189 , Issue.7 , pp. 1073-1081
    • Zeng, D.1    Lewis, D.2    Dejbakhsh-Jones, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.