Acteoside from Cistanche salsa inhibits apoptosis by 1-methyl-4-phenylpyridinium ion in cerebellar granule neurons

Planta Medica

Volumn 69, Issue 1, 2003, Pages 65-66

  Pu, Xiaoping ^a   Song, Zhihong ^a   Li, Yanyun ^a   Tu, Pengfei ^a   Li, Huinong ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ACTEOSIDE; CASPASE 3; LACTATE DEHYDROGENASE; NEUROTOXIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL VIABILITY; CEREBELLUM; CISTANCHE SALSA; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; FLOW CYTOMETRY; GRANULE CELL; NEUROPROTECTION; NONHUMAN; PLANT; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; CELL SURVIVAL; CEREBELLUM; CHINA; CISTANCHE; GLUCOSIDES; NEURONS; PHENOLS; RATS;

ANIMALIA; CISTANCHE; CISTANCHE SALSA;

EID: 0345505713     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-37029     Document Type: Article

References (7)

1. Jimenez CC, Riguera R. Phenylethanoid glycosides in plants: Structure and biological activity. Nat Prod Rep. 1994; 11: 596-606
2. Xiong QB, Hase K, Tezuka Y, Namba T, Kadota S. Acteoside inhibits apoptosis in D-galactosamine and lipopolysaccharide induced liver injury. Life Sci. 1999; 65: 421-30
3. +) and protection by EGF in GH3 cells. Brain Res. 1998; 794: 137-42
4. Du Y, Dodel RC, Bales KR, Jemmerson R, Hamilton BE, Paul SM. Involvement of a caspase-like cysteine protease in 1-methyl-4-phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons. J. Neurochem. 1997; 69: 1382-88
5. Lei L, Yang FQ, Zhang TY, Tu PF, Wu LJ, Ito Y. Preparative isolation and purification of acteoside and 2′-acetylacteoside from Cistanche salsa (C.A. Mey.) G. Beck by high-speed counter-current chromatography. Journal of Chromatography A. 2001; 912: 181-5
6. Levi G, Aloisi F, Ciotti MT, Gallo V. Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cultured cerebellar granule cells. Brain Res. 1984; 290: 77-86
7. Murphy TH, Miyamoto M, Sastre A, Schnaar RL, Coyle JT. Calcium-dependent glutamate cytotoxicity in a neuronal cell line. Brain Res. 1988; 444: 325-32