Decreased expression and the Lys751Gln polymorphism of the XPD gene are associated with extreme longevity

Biogerontology

Volumn 11, Issue 3, 2010, Pages 287-297

  Polosak, Jacek ^a   Roszkowska Gancarz, Malgorzata ^a   Kurylowicz, Alina ^b   Owczarz, Magdalena ^c   Dobosz, Paulina ^a   Mossakowska, Malgorzata ^c   Szybinska, Aleksandra ^c   Puzianowska Kuznicka, Monika ^b  

^a MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^c INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

Author keywords

Aging; Centenarians; Expression; Genetic polymorphism; Longevity; Promoter methylation; Xeroderma pigmentosum complementation group D gene (XPD)

Indexed keywords

DNA; MESSENGER RNA; XERODERMA PIGMENTOSUM GROUP D PROTEIN;

ADULT; AGED; AGING; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOMIC INSTABILITY; GENOTYPE; GROUPS BY AGE; HOMOZYGOSITY; HUMAN; LONGEVITY; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; SENESCENCE; TRANSCRIPTION INITIATION SITE;

ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; DNA METHYLATION; DNA PRIMERS; GLYCINE; HUMANS; LONGEVITY; LYSINE; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROMOTER REGIONS, GENETIC; XERODERMA PIGMENTOSUM GROUP D PROTEIN;

EID: 77954817812     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-009-9246-y     Document Type: Article

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