Genotypes and haplotypes of ERCC1 and ERCC2/XPD genes predict levels of benzo[a]pyrene diol epoxide-induced DNA adducts in cultured primary lymphocytes from healthy individuals: A genotype-phenotype correlation analysis

Carcinogenesis

Volumn 29, Issue 8, 2008, Pages 1560-1566

  Zhao, Hui ^a   Wang, Li E ^a   Li, Donghui ^a   Chamberlain, Robert M ^a   Sturgis, Erich M ^a   Wei, Qingyi ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROXYBENZO[A]PYRENE OXIDE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; XERODERMA PIGMENTOSUM GROUP D PROTEIN;

ADULT; AGED; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; COVARIANCE; DNA ADDUCT; EXCISION REPAIR; FEMALE; GENETIC ASSOCIATION; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; HAPLOTYPE; HOMOZYGOSITY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VITRO STUDY; LYMPHOCYTE CULTURE; MALE; NORMAL HUMAN; PREDICTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; STATISTICAL SIGNIFICANCE; WILD TYPE;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; DNA ADDUCTS; DNA REPAIR; DNA-BINDING PROTEINS; ENDONUCLEASES; GENOTYPE; HUMANS; LYMPHOCYTES; PHENOTYPE; REFERENCE VALUES; XERODERMA PIGMENTOSUM GROUP D PROTEIN;

EID: 49649126440     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgn089     Document Type: Article

References (38)

1. Kyrtopoulos,S.A. (2006) Biomarkers in environmental carcinogenesis research: Striving for a new momentum. Toxicol. Lett., 162, 3-15.
2. Li,D. et al. (2007) In vitro benzo [a]pyrene diol epoxide-induced DNA adducts and risk of squamous cell carcinoma of head and neck. Cancer Res., 67, 5628-5634.
3. Binkova,B. et al. (2007) PAH-DNA adducts in environmentally exposed population in relation to metabolic and DNA repair gene polymorphisms. Mutat. Res., 620, 49-61.
4. Farmer,P.B. et al. (2003) Molecular epidemiology studies of carcinogenic environmental pollutants. Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage. Mutat. Res., 544, 397-402.
5. Stephens,J.C. et al. (2001) Haplotype variation and linkage disequilibrium in 313 human genes. Science, 293, 489-493.
6. Reardon,J.T. et al. (2005) Nucleotide excision repair. Prog. Nucleic Acid Res. Mol. Biol., 79, 183-235.
7. Qiao,Y. et al. (2002) Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes. Carcinogenesis, 23, 295-299.
8. Li,D. et al. (1996) In vitro induction of benzo(a pyrene diol epoxide-DNA adducts in peripheral lymphocytes as a susceptibility marker for human lung cancer. Cancer Res., 56 3638-3641.
9. Li,D. et al. (2001) In vitro BPDE-induced DNA adducts in peripheral lymphocytes as a risk factor for squamous cell carcinoma of the head and neck. Int. J. Cancer, 93, 436-440.
10. Li,D. et al. (2001) Sensitivity to DNA damage induced by benzo( a)pyrene diol epoxide and risk of lung cancer: A case-control analysis. Cancer Res., 61, 1445-1450.
11. Neumann,A.S. et al. (2005) Nucleotide excision repair as a marker for susceptibility to tobacco-related cancers: A review of molecular epidemiological studies. Mol. Carcinog., 42, 65-92.
12. Volker,M. et al. (2001) Sequential assembly of the nucleotide excision repair factors in vivo. Mol. Cell, 8, 213-224.
13. An,J. et al. (2007) Potentially functional single nucleotide polymorphisms in the core nucleotide excision repair genes and risk of squamous cell carcinoma of the head and neck. Cancer Epidemiol. Biomarkers Prev., 16, 1633-1638.
14. Agresti,A. (2002) Categorical Data Analysis. Wiley Interscience, New York.
15. Saxton,A.M. (2004) Genetic Analysis of Complex Traits Using SAS. SAS Institute Inc, Cary, NC.
16. Stephens,M. et al. (2003) A comparison of Bayesian methods for haplotype reconstruction from population genotype data. Am. J. Hum. Genet., 73, 1162-1169.
17. Stephens,M. et al. (2001) A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet., 68, 978-989.
18. Stephens,M. et al. (2005) Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am. J. Hum. Genet., 76, 449-462.
19. Feigelson,H.S. et al. (2006) Haplotype analysis of the HSD17B1 gene and risk of breast cancer: A comprehensive approach to multicenter analyses of prospective cohort studies. Cancer Res., 66, 2468-2475.
20. Wacholder,S. et al. (2004) Assessing the probability that a positive report is false: An approach for molecular epidemiology studies. J. Natl Cancer Inst., 96, 434-442.
21. Manuguerra,M. et al. (2006) XRCC3 and XPD/ERCC2 single nucleotide polymorphisms and the risk of cancer: A HuGE review. Am. J. Epidemiol., 164, 297-302.
22. Matullo,G. et al. (2006) DNA repair polymorphisms and cancer risk in non-smokers in a cohort study. Carcinogenesis, 27, 997-1007.
23. Crew,K.D. et al. (2007) Polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-DNA adducts, and breast cancer risk. Cancer Epidemiol. Biomarkers Prev., 16, 2033-2041.
24. Berwick,M. et al. (2000) Markers of DNA repair and susceptibility to cancer in humans: An epidemiologic review. J. Natl Cancer Inst. 92, 874-897.
25. Matullo,G. et al. (2001) XRCC1, XRCC3, XPD gene polymorphisms, smoking and (32)P-DNA adducts in a sample of healthy subjects. Carcinogenesis, 22, 1437-1445.
26. Veglia,F. et al. (2003) Bulky DNA adducts and risk of cancer: A meta-analysis. Cancer Epidemiol. Biomarkers Prev., 12, 157-160.
27. Lovatt,T. et al. (2005) Polymorphism in the nuclear excision repair gene ERCC2/XPD: Association between an exon 6-exon 10 haplotype and susceptibility to cutaneous basal cell carcinoma. Hum. Mutat., 25, 353-359.
28. Li,D. et al. (1996) Aromatic DNA adducts in adjacent tissues of breast cancer patients: Clues to breast cancer etiology. Cancer Res. 56, 287-293.
29. Tang,D. et al. (2002) Polymorphisms in the DNA repair enzyme XPD are associated with increased levels of PAH-DNA adducts in a case-control study of breast cancer. Breast Cancer Res. Treat., 75, 159-166.
30. Wei,Q. et al. (1993) DNA repair and aging in basal cell carcinoma: a molecular epidemiology study. Proc. Natl Acad. Sci. USA, 90 1614-1618.
31. Wei,Q. et al. (2000) Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: A molecular epidemiologic study. J. Natl Cancer Inst., 92, 1764-1772.
32. Wei,Q. et al. (2003) Repair of UV light-induced DNA damage and risk of cutaneous malignant melanoma. J. Natl Cancer Inst., 95 308-315.
33. Matta,J.L. et al. (2003) DNA repair and nonmelanoma skin cancer in Puerto Rican populations. J. Am. Acad. Dermatol., 49, 433-439.
34. Shi,Q. et al. (2004) Reduced DNA repair of benzo [a]pyrene diol epoxideinduced adducts and common XPD polymorphisms in breast cancer patients. Carcinogenesis, 25, 1695-1700.
35. Hu,J.J. et al. (2004) Deficient nucleotide excision repair capacity enhances human prostate cancer risk. Cancer Res., 64 1197-1201.
36. Kennedy,D.O. et al. (2005) DNA repair capacity of lymphoblastoid cell lines from sisters discordant for breast cancer. J. Natl Cancer Inst., 97, 127-132.
37. Goode,E.L. et al. (2002) Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol. Biomarkers Prev., 11, 1513-1530.
38. Vogel,U. et al. (2004) Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer. Mutat. Res., 546, 65-74.