-
1
-
-
33745056414
-
-
Agrelo R, Cheng WH, Setien F, Ropero S, Espada J et al (2006) Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. Proc Natl Acad Sci USA 103:8822-8827
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8822
-
-
Agrelo1
-
2
-
-
33846049673
-
-
Brouilette SW, Moore JS, McMahon AD, Thompson JR, Ford I et al (2007) Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. Lancet 369:107-114
-
(2007)
Lancet
, vol.369
, pp. 107
-
-
Brouilette1
-
3
-
-
33846256163
-
-
Gennery AR (2006) Primary immunodeficiency syndromes associated with defective DNA double-strand break repair. Brit Med Bull 78:71-85
-
(2006)
Brit Med Bull
, vol.78
, pp. 71
-
-
Gennery1
-
4
-
-
35548952136
-
Human aging and longevity: Genetic aspects
-
Osiewacz HD (ed) Kluwer Academic Publishers
-
Hoehn H, Renner A (2003) Human aging and longevity: genetic aspects. In: Osiewacz HD (ed) Aging of Organisms, Kluwer Academic Publishers, pp 247-269
-
(2003)
Aging of Organisms
, pp. 247-269
-
-
Hoehn, H.1
Renner, A.2
-
5
-
-
33744990645
-
-
Huang S, Lee L, Hanson NB. Lenaerts C, Hoehn H et al (2006) The spectrum of WRN mutations in Werner syndrome patients. Hum Mutat 27:558-567
-
(2006)
Hum Mutat
, vol.27
, pp. 558
-
-
Huang1
-
6
-
-
33645091213
-
-
Huck K, Hanenberg H, Gudowius S, Fenk R, Kalb R et al (2006) Delayed diagnosis and complications of Fanconi anaemia at advanced age - a paradigm. Br J Haematol 133:188-197
-
(2006)
Br J Haematol
, vol.133
, pp. 188
-
-
Huck1
-
7
-
-
0019444973
-
-
Joenje H, Arwert F, Eriksson AW, de Koning H, Oostra AB (1981) Oxygendependence of chromosomal aberrations in Fanconi's anaemia. Nature 290:142-143
-
(1981)
Nature
, vol.290
, pp. 142
-
-
Joenje1
-
8
-
-
2442658200
-
-
Kalb R, Duerr M, Wagner M, Herterich S, Gross M et al (2004) Lack of sensitivity of primary Fanconi's anemia fibroblasts to UV and ionizing radiation. Radiat Res 161:318-325
-
(2004)
Radiat Res
, vol.161
, pp. 318
-
-
Kalb1
-
9
-
-
34247390746
-
-
Kudlow BA, Kennedy BK, Monnat RJ (2007) Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases. Nat Rev Mol Cell Biol 8:394-404
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 394
-
-
Kudlow1
-
10
-
-
33644541793
-
-
Kyng KJ, Bohr VA (2005) Gene expression and DNA repair in progeroid syndromes and human aging. Ageing Res Rev 4:579-602
-
(2005)
Ageing Res Rev
, vol.4
, pp. 579
-
-
Kyng1
-
11
-
-
33846283384
-
-
Lanctôt C, Cheutin R, Cremer M, Cavalli G, Cremer T (2007) Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions. Nat Rev Genet 8:104-115
-
(2007)
Nat Rev Genet
, vol.8
, pp. 104
-
-
Lanctôt1
-
12
-
-
10944225939
-
-
Lee JW, Harrigan J, Opresko PL, Bohr VA (2005) Pathways and functions of the Werner syndrome protein. Mech Ageing Dev 126:79-86
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 79
-
-
Lee1
-
13
-
-
0034626770
-
-
Martin GM, Oshima J (2000) Lessons from human progeroid syndromes. Nature 408:263-266
-
(2000)
Nature
, vol.408
, pp. 263
-
-
Martin1
-
14
-
-
13944280713
-
-
Martin GM (2005) Genetic modulation of senescent phenotypes in Homo sapiens. Cell 120:523-532
-
(2005)
Cell
, vol.120
, pp. 523
-
-
Martin1
-
15
-
-
34247584926
-
Chromosome instability in normative aging
-
Hisama FM, Weissman SM, Martin GM (eds) Chromosomal Instability and Aging Marcel Dekker, New York
-
Maurer B, Guttenbach M, Schmid M (2003) Chromosome instability in normative aging. In: Hisama FM, Weissman SM, Martin GM (eds) Chromosomal Instability and Aging. Basic Science and Clinical Implications, Marcel Dekker, New York, pp 125-147
-
(2003)
Basic Science and Clinical Implications
, pp. 125-147
-
-
Maurer, B.1
Guttenbach, M.2
Schmid, M.3
-
16
-
-
0034486160
-
-
Melcher R, von Golitschek R, Steinlein C, Schindler D, Neitzel H et al (2000) Spectral karyotyping of Werner syndrome fibroblast cultures. Cytogenet Cell Genet 91:180-185
-
(2000)
Cytogenet Cell Genet
, vol.91
, pp. 180
-
-
Melcher1
-
17
-
-
33750378214
-
-
Mukhopadhyay SS, Leung KS, Hicks MJ, Hastings PJ, Youssoufian H et al (2006) Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia. J Cell Biol 175:225-235
-
(2006)
J Cell Biol
, vol.175
, pp. 225
-
-
Mukhopadhyay1
-
18
-
-
34447316414
-
-
Muller FL, Lustgarten MS, Jang Y, Richardson A, Van Remmen H (2007) Trends in oxidative aging theories. Free Radic Biol Med 43:477-503
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 477
-
-
Muller1
-
19
-
-
35548931929
-
Cancer in Fanconi anemia and Fanconi anemia genes in cancer
-
Schindler D, Hoehn H (eds) Fanconi anemia. A paradigmatic disease fort he understanding of cancer and aging Basel
-
Neveling K, Kalb R, Schindler D (2007) Cancer in Fanconi anemia and Fanconi anemia genes in cancer. In: Schindler D, Hoehn H (eds) Fanconi anemia. A paradigmatic disease fort he understanding of cancer and aging. Monogr Hum Genet. Karger, Basel, vol 15, pp 59-78
-
(2007)
Monogr Hum Genet. Karger
, vol.15
, pp. 59-78
-
-
Neveling, K.1
Kalb, R.2
Schindler, D.3
-
21
-
-
33845914051
-
-
Niedernhofer LJ, Garinis GA, Raams A, Lalai AS, Robinson AR et al (2006) A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis. Nature 444:1038-1043
-
(2006)
Nature
, vol.444
, pp. 1038
-
-
Niedernhofer1
-
22
-
-
34250001450
-
-
Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T et al (2007) DNA repair is limiting for haematopoietic stem cells during ageing. Nature 447:686-690
-
(2007)
Nature
, vol.447
, pp. 686
-
-
Nijnik1
-
23
-
-
12444257433
-
-
Pagano G, Youssoufian H (2003) Fanconi anaemia proteins: major roles in cell protection against oxidative damage. Bioessays 25:589-595
-
(2003)
Bioessays
, vol.25
, pp. 589
-
-
Pagano1
-
24
-
-
22444431937
-
-
Pagano G, Degan P, d'Ischia M, Kelly FJ, Nobili B et al (2005) Oxidative stress as a multiple effector in Fanconi anaemia clinical phenotype. Eur J Haematol 75:93-100
-
(2005)
Eur J Haematol
, vol.75
, pp. 93
-
-
Pagano1
-
25
-
-
3142666893
-
-
Park SJ, Ciccone SL, Beck BD, Hwang B, Freie B et al (2004) Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. J Biol Chem 279:30053-30059
-
(2004)
J Biol Chem
, vol.279
, pp. 30053
-
-
Park1
-
26
-
-
14544268189
-
-
Park Y, Gerson SL (2005) DNA repair defects in stem cell function and aging. Annu Rev Med 56:495-508
-
(2005)
Annu Rev Med
, vol.56
, pp. 495
-
-
Park1
-
27
-
-
34249931173
-
-
Patel KJ, Joenje H (2007) Fanconi anemia and DNA replication repair. DNA Repair (Amst) 6:885-890
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 885
-
-
Patel1
-
28
-
-
34250007142
-
-
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J et al (2007) Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 447:725-729
-
(2007)
Nature
, vol.447
, pp. 725
-
-
Rossi1
-
29
-
-
33646745137
-
-
Scaffidi P, Misteli T (2006) Lamin Adependent nuclear defects in human aging. Science 312:1059-1063
-
(2006)
Science
, vol.312
, pp. 1059
-
-
Scaffidi1
-
30
-
-
0023685747
-
-
Schindler D, Hoehn H (1988) Fanconi anemia mutation causes cellular susceptibility to ambient oxygen. Am J Hum Genet 43:429-435
-
(1988)
Am J Hum Genet
, vol.43
, pp. 429
-
-
Schindler1
-
31
-
-
84870178175
-
Applications of cell cycle testing in Fanconi anemia
-
Schindler D, Hoehn H (eds) Fanconi anemia. A paradigmatic disease fort he understanding of cancer and aging Basel
-
Schindler D, Friedl R, Gavvovidis I, Kalb R, Neveling K et al (2007) Applications of cell cycle testing in Fanconi anemia. In: Schindler D, Hoehn H (eds) Fanconi anemia. A paradigmatic disease fort he understanding of cancer and aging. Monogr Hum Genet. Karger, Basel, vol 15, pp 110-130
-
(2007)
Monogr Hum Genet. Karger
, vol.15
, pp. 110-130
-
-
Schindler, D.1
Friedl, R.2
Gavvovidis, I.3
Kalb, R.4
Al Et, N.K.5
-
32
-
-
34249780384
-
-
Thoms KM, Kuschal C, Emmert S (2007) Lessons learned from DNA repair defective syndromes. Exp Dermatol 16:532-544
-
(2007)
Exp Dermatol
, vol.16
, pp. 532
-
-
Thoms1
-
33
-
-
34047261274
-
-
Trivin C, Gluckman E, Leblanc T, Cousin MN, Soulier J, Brauner R (2007) Factors and markers of growth hormone secretion and gonadal function in Fanconi anemia. Growth Hormone and IGF Research 17:122-129
-
(2007)
Growth Hormone and IGF Research
, vol.17
, pp. 122
-
-
Trivin1
-
34
-
-
33745516977
-
-
Vulliamy T, Dokal I (2006) Dyskeratosis congenita. Semin Hematol 43:157-166
-
(2006)
Semin Hematol
, vol.43
, pp. 157
-
-
Vulliamy1
-
35
-
-
17744365737
-
-
Wajnrajch MP, Gertner JM, Huma Z, Popovic J, Lin K et al (2001) Evaluation of growth and hormonal status in patients referred to the International Fanconi Anemia Registry. Pediatrics 107:744-754
-
(2001)
Pediatrics
, vol.107
, pp. 744
-
-
Wajnrajch1
-
36
-
-
34548759123
-
Emergence of a DNA damage response network consisting of Fanconi Anemia and BRCA Proteins
-
Wang W (2007) Emergence of a DNA damage response network consisting of Fanconi Anemia and BRCA Proteins. Nat Rev Genet (in press)
-
(2007)
Nat Rev Genet (In Press)
-
-
Wang, W.1
-
37
-
-
22044452387
-
-
Zhang X, Li J, Sejas DP, Pang Q (2005) Hypoxia-reoxygenation induces premature senescence in FA bone marrow hematopoietic cells. Blood 106:75-85
-
(2005)
Blood
, vol.106
, pp. 75
-
-
Zhang1
-
38
-
-
34249671829
-
-
Zhang X, Sejas DP, Qiu Y, Williams DA, Pang Q (2007) Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence. J Cell Sci 120:1572-1583
-
(2007)
J Cell Sci
, vol.120
, pp. 1572
-
-
Zhang1
|