RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 25, 2002, Pages 16162-16167

  Kirby, Kim ^a   Hu, Jianguo ^a   Hilliker, Arthur J ^b   Phillips, John P ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b YORK UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITATE HYDRATASE; ANTIOXIDANT; FUMARATE HYDRATASE; IRON SULFUR PROTEIN; PARAQUAT; PROTEIN; PROTEIN SOD2; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

AGING; ARTICLE; CITRIC ACID CYCLE; DROSOPHILA; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENE SILENCING; METAMORPHOSIS; MITOCHONDRIAL RESPIRATION; MORTALITY; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; TRANSGENE;

ANIMALS; CITRIC ACID CYCLE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; DRUG RESISTANCE; ELECTRON TRANSPORT; IRON-SULFUR PROTEINS; ISOENZYMES; LONGEVITY; MITOCHONDRIA; OXIDATIVE STRESS; PARAQUAT; PROMOTER REGIONS (GENETICS); REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SACCHAROMYCES CEREVISIAE PROTEINS; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS; TRANSGENES;

ANIMALIA;

EID: 0037059057     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.252342899     Document Type: Article

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