메뉴 건너뛰기




Volumn 5, Issue 4, 2010, Pages 545-555

MiRNA in pluripotent stem cells

Author keywords

embryonic stem cells; epigenetics; induced pluripotent stem cells; miRNA

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; DICER; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MEMBRANE PROTEIN; MICRORNA; PROTEIN LET 7; UNCLASSIFIED DRUG;

EID: 77954811476     PISSN: 17460751     EISSN: None     Source Type: Journal    
DOI: 10.2217/rme.10.34     Document Type: Review
Times cited : (32)

References (129)
  • 1
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al.: Embryonic stem cell lines derived from human blastocysts. Science 282(5391), 1145-1147 (1998).
    • (1998) Science , vol.282 , Issue.5391 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 3
    • 41949134533 scopus 로고    scopus 로고
    • Generation of pluripotent stem cells from adult mouse liver and stomach cells
    • Aoi T, Yae K, Nakagawa M, et al.: Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321(5889), 699-702 (2008).
    • (2008) Science , vol.321 , Issue.5889 , pp. 699-702
    • Aoi, T.1    Yae, K.2    Nakagawa, M.3
  • 4
    • 39149086020 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from fibroblast cultures
    • Takahashi K, Okita K, Nakagawa M, Yamanaka S: Induction of pluripotent stem cells from fibroblast cultures. Nat. Protoc. 2(12), 3081-3089 (2007).
    • (2007) Nat. Protoc. , vol.2 , Issue.12 , pp. 3081-3089
    • Takahashi, K.1    Okita, K.2    Nakagawa, M.3    Yamanaka, S.4
  • 5
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, et al.: Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131(5), 861-872 (2007).
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 6
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa M, Koyanagi M, Tanabe K, et al.: Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26(1), 101-106 (2008).
    • (2008) Nat. Biotechnol. , vol.26 , Issue.1 , pp. 101-106
    • Nakagawa, M.1    Koyanagi, M.2    Tanabe, K.3
  • 7
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park IH, Zhao R, West JA, et al.: Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451(7175), 141-146 (2008).
    • (2008) Nature , vol.451 , Issue.7175 , pp. 141-146
    • Park, I.H.1    Zhao, R.2    West, J.A.3
  • 8
    • 34249909232 scopus 로고    scopus 로고
    • Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
    • Maherali N, Sridharan R, Xie W, et al.: Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1(1), 55-70 (2007).
    • (2007) Cell Stem Cell , vol.1 , Issue.1 , pp. 55-70
    • Maherali, N.1    Sridharan, R.2    Xie, W.3
  • 9
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K, et al.: Induced pluripotent stem cell lines derived from human somatic cells. Science 318(5858), 1917-1920 (2007).
    • (2007) Science , vol.318 , Issue.5858 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 11
    • 67649342825 scopus 로고    scopus 로고
    • Patient-specific pluripotent stem cells: Promises and challenges
    • Muller R, Lengerke C: Patient-specific pluripotent stem cells: promises and challenges. Nat. Rev. Endocrinol. 5(4), 195-203 (2009).
    • (2009) Nat. Rev. Endocrinol. , vol.5 , Issue.4 , pp. 195-203
    • Muller, R.1    Lengerke, C.2
  • 12
    • 70349815098 scopus 로고    scopus 로고
    • Disease models from pluripotent stem cells
    • Lengerke C, Daley GQ: Disease models from pluripotent stem cells. Ann. NY Acad. Sci. 1176, 191-196 (2009).
    • (2009) Ann. NY Acad. Sci. , vol.1176 , pp. 191-196
    • Lengerke, C.1    Daley, G.Q.2
  • 13
    • 71649102823 scopus 로고    scopus 로고
    • Autologous blood cell therapies from pluripotent stem cells
    • Lengerke C, Daley GQ: Autologous blood cell therapies from pluripotent stem cells. Blood Rev. 24(1), 27-37 (2010).
    • (2010) Blood Rev. , vol.24 , Issue.1 , pp. 27-37
    • Lengerke, C.1    Daley, G.Q.2
  • 14
    • 44649117905 scopus 로고    scopus 로고
    • Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
    • Chen X, Xu H, Yuan P, et al.: Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133(6), 1106-1117 (2008).
    • (2008) Cell , vol.133 , Issue.6 , pp. 1106-1117
    • Chen, X.1    Xu, H.2    Yuan, P.3
  • 15
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF, et al.: Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122(6), 947-956 (2005).
    • (2005) Cell , vol.122 , Issue.6 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 16
    • 39149130361 scopus 로고    scopus 로고
    • Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
    • Jaenisch R, Young R: Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132(4), 567-582 (2008).
    • (2008) Cell , vol.132 , Issue.4 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 17
    • 48049098134 scopus 로고    scopus 로고
    • Molecular basis of pluripotency
    • Chen L, Daley GQ: Molecular basis of pluripotency. Human Mol. Genet. 17(R1), R23-R27 (2008).
    • (2008) Human Mol. Genet. , vol.17 , Issue.1
    • Chen, L.1    Daley, G.Q.2
  • 18
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh YH, Wu Q, Chew JL, et al.: The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat. Genet. 38(4), 431-440 (2006).
    • (2006) Nat. Genet. , vol.38 , Issue.4 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3
  • 19
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by polycomb in human embryonic stem cells
    • Lee TI, Jenner RG, Boyer LA, et al.: Control of developmental regulators by polycomb in human embryonic stem cells. Cell 125(2), 301-313 (2006).
    • (2006) Cell , vol.125 , Issue.2 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3
  • 21
    • 34250330770 scopus 로고    scopus 로고
    • Characterization of DNA methylation change in stem cell marker genes during differentiation of human embryonic stem cells
    • Yeo S, Jeong S, Kim J, Han JS, Han YM, Kang YK: Characterization of DNA methylation change in stem cell marker genes during differentiation of human embryonic stem cells. Biochem. Biophys. Res. Commun. 359(3), 536-542 (2007).
    • (2007) Biochem. Biophys. Res. Commun. , vol.359 , Issue.3 , pp. 536-542
    • Yeo, S.1    Jeong, S.2    Kim, J.3    Han, J.S.4    Han, Y.M.5    Kang, Y.K.6
  • 22
    • 38649126918 scopus 로고    scopus 로고
    • Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation
    • Fouse SD, Shen Y, Pellegrini M, et al.: Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell 2(2), 160-169 (2008).
    • (2008) Cell Stem Cell , vol.2 , Issue.2 , pp. 160-169
    • Fouse, S.D.1    Shen, Y.2    Pellegrini, M.3
  • 23
    • 51649129596 scopus 로고    scopus 로고
    • Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
    • Mohn F, Weber M, Rebhan M, et al.: Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol. Cell 30(6), 755-766 (2008).
    • (2008) Mol. Cell , vol.30 , Issue.6 , pp. 755-766
    • Mohn, F.1    Weber, M.2    Rebhan, M.3
  • 25
    • 33748928159 scopus 로고    scopus 로고
    • The diverse functions of microRNAs in animal development and disease
    • Kloosterman WP, Plasterk RH: The diverse functions of microRNAs in animal development and disease. Dev. Cell 11(4), 441-450 (2006).
    • (2006) Dev. Cell , vol.11 , Issue.4 , pp. 441-450
    • Kloosterman, W.P.1    Plasterk, R.H.2
  • 26
    • 38949133183 scopus 로고    scopus 로고
    • MicroRNAs: Small molecules with big roles - C. elegans to human cancer
    • Kato M, Slack FJ: MicroRNAs: small molecules with big roles - C. elegans to human cancer. Biol. Cell 100(2), 71-81 (2008).
    • (2008) Biol. Cell , vol.100 , Issue.2 , pp. 71-81
    • Kato, M.1    Slack, F.J.2
  • 27
    • 39749110083 scopus 로고    scopus 로고
    • Small non-coding RNAs in animal development
    • Stefani G, Slack FJ: Small non-coding RNAs in animal development. Nat. Rev. 9(3), 219-230 (2008).
    • (2008) Nat. Rev. , vol.9 , Issue.3 , pp. 219-230
    • Stefani, G.1    Slack, F.J.2
  • 28
    • 12544255565 scopus 로고    scopus 로고
    • Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
    • Zeng Y, Yi R, Cullen BR: Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J. 24(1), 138-148 (2005).
    • (2005) EMBO J. , vol.24 , Issue.1 , pp. 138-148
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3
  • 29
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN: The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18(24), 3016-3027 (2004).
    • (2004) Genes Dev. , vol.18 , Issue.24 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Kim, Y.K.4    Jin, H.5    Kim, V.N.6
  • 30
    • 4444230672 scopus 로고    scopus 로고
    • Structural requirements for pre-microRNA binding and nuclear export by exportin 5
    • Zeng Y, Cullen BR: Structural requirements for pre-microRNA binding and nuclear export by exportin 5. Nucleic Acids Res. 32(16), 4776-4785 (2004).
    • (2004) Nucleic Acids Res. , vol.32 , Issue.16 , pp. 4776-4785
    • Zeng, Y.1    Cullen, B.R.2
  • 31
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116(2), 281-297 (2004).
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 32
    • 0038299558 scopus 로고    scopus 로고
    • Role of microRNAs in plant and animal development
    • Carrington JC, Ambros V: Role of microRNAs in plant and animal development. Science 301(5631), 336-338 (2003).
    • (2003) Science , vol.301 , Issue.5631 , pp. 336-338
    • Carrington, J.C.1    Ambros, V.2
  • 33
    • 0037686295 scopus 로고    scopus 로고
    • Killing the messenger: Short RNAs that silence gene expression
    • Dykxhoorn DM, Novina CD, Sharp PA: Killing the messenger: short RNAs that silence gene expression. Nat. Rev. 4(6), 457-467 (2003).
    • (2003) Nat. Rev. , vol.4 , Issue.6 , pp. 457-467
    • Dykxhoorn, D.M.1    Novina, C.D.2    Sharp, P.A.3
  • 35
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: MicroRNAs can up-regulate translation
    • Vasudevan S, Tong Y, Steitz JA: Switching from repression to activation: microRNAs can up-regulate translation. Science 318(5858), 1931-1934 (2007).
    • (2007) Science , vol.318 , Issue.5858 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 36
    • 50149095122 scopus 로고    scopus 로고
    • Endogenous small interfering RNAs in animals
    • Okamura K, Lai EC: Endogenous small interfering RNAs in animals. Nat. Rev. 9(9), 673-678 (2008).
    • (2008) Nat. Rev. , vol.9 , Issue.9 , pp. 673-678
    • Okamura, K.1    Lai, E.C.2
  • 37
    • 68549085526 scopus 로고    scopus 로고
    • A novel epigenetic mechanism in Drosophila somatic cells mediated by Piwi and piRNAs
    • Lin H, Yin H: A novel epigenetic mechanism in Drosophila somatic cells mediated by Piwi and piRNAs. Cold Spring Harb. Symp. Quant. Biol. 73, 273-281 (2008).
    • (2008) Cold Spring Harb. Symp. Quant. Biol. , vol.73 , pp. 273-281
    • Lin, H.1    Yin, H.2
  • 38
    • 70350238350 scopus 로고    scopus 로고
    • The biogenesis and function of Piwi proteins and piRNAs: Progress and prospect
    • Thomson T, Lin H: The biogenesis and function of Piwi proteins and piRNAs: progress and prospect. Ann. Rev. Cell Dev. Biol. 25, 355-376 (2009).
    • (2009) Ann. Rev. Cell Dev. Biol. , vol.25 , pp. 355-376
    • Thomson, T.1    Lin, H.2
  • 39
    • 36048937264 scopus 로고    scopus 로고
    • An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster
    • Yin H, Lin H: An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature 450(7167), 304-308 (2007).
    • (2007) Nature , vol.450 , Issue.7167 , pp. 304-308
    • Yin, H.1    Lin, H.2
  • 40
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman RC, Farh KK, Burge CB, Bartel DP: Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19(1), 92-105 (2009).
    • (2009) Genome Res. , vol.19 , Issue.1 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 43
    • 33750318273 scopus 로고    scopus 로고
    • A guide through present computational approaches for the identification of mammalian microRNA targets
    • Sethupathy P, Megraw M, Hatzigeorgiou AG: A guide through present computational approaches for the identification of mammalian microRNA targets. Nat. Methods 3(11), 881-886 (2006).
    • (2006) Nat. Methods , vol.3 , Issue.11 , pp. 881-886
    • Sethupathy, P.1    Megraw, M.2    Hatzigeorgiou, A.G.3
  • 44
    • 26944443861 scopus 로고    scopus 로고
    • Identification and characterization of small RNAs involved in RNA silencing
    • Aravin A, Tuschl T: Identification and characterization of small RNAs involved in RNA silencing. FEBS Lett. 579(26), 5830-5840 (2005).
    • (2005) FEBS Lett. , vol.579 , Issue.26 , pp. 5830-5840
    • Aravin, A.1    Tuschl, T.2
  • 45
    • 40949114603 scopus 로고    scopus 로고
    • Concise review: MicroRNA expression in multipotent mesenchymal stromal cells
    • Lakshmipathy U, Hart RP: Concise review: microRNA expression in multipotent mesenchymal stromal cells. Stem Cells 26(2), 356-363 (2008).
    • (2008) Stem Cells , vol.26 , Issue.2 , pp. 356-363
    • Lakshmipathy, U.1    Hart, R.P.2
  • 46
    • 67349176636 scopus 로고    scopus 로고
    • MicroRNA detection by microarray
    • Li W, Ruan K: MicroRNA detection by microarray. Anal. Bioanal. Chem. 394(4), 1117-1124 (2009).
    • (2009) Anal. Bioanal. Chem. , vol.394 , Issue.4 , pp. 1117-1124
    • Li, W.1    Ruan, K.2
  • 47
    • 69249147045 scopus 로고    scopus 로고
    • Expression profiling of microRNAs by deep sequencing
    • Creighton CJ, Reid JG, Gunaratne PH: Expression profiling of microRNAs by deep sequencing. Brief Bioinform. 10(5), 490-497 (2009).
    • (2009) Brief Bioinform. , vol.10 , Issue.5 , pp. 490-497
    • Creighton, C.J.1    Reid, J.G.2    Gunaratne, P.H.3
  • 48
    • 67649595548 scopus 로고    scopus 로고
    • Limitations and possibilities of small RNA digital gene expression profiling
    • Linsen SE, de Wit E, Janssens G, et al.: Limitations and possibilities of small RNA digital gene expression profiling. Nat. Methods 6(7), 474-476 (2009).
    • (2009) Nat. Methods , vol.6 , Issue.7 , pp. 474-476
    • Linsen, S.E.1    De Wit, E.2    Janssens, G.3
  • 49
    • 70349690162 scopus 로고    scopus 로고
    • Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors
    • Goff LA, Davila J, Swerdel MR, et al.: Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. PLoS ONE 4(9), e7192 (2009).
    • (2009) PLoS ONE , vol.4 , Issue.9
    • Goff, L.A.1    Davila, J.2    Swerdel, M.R.3
  • 50
    • 0042442335 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs
    • Houbaviy HB, Murray MF, Sharp PA: Embryonic stem cell-specific microRNAs. Dev. Cell 5(2), 351-358 (2003).
    • (2003) Dev. Cell , vol.5 , Issue.2 , pp. 351-358
    • Houbaviy, H.B.1    Murray, M.F.2    Sharp, P.A.3
  • 51
    • 2942534403 scopus 로고    scopus 로고
    • Human embryonic stem cells express a unique set of microRNAs
    • Suh MR, Lee Y, Kim JY, et al.: Human embryonic stem cells express a unique set of microRNAs. Dev. Biol. 270(2), 488-498 (2004).
    • (2004) Dev. Biol. , vol.270 , Issue.2 , pp. 488-498
    • Suh, M.R.1    Lee, Y.2    Kim, J.Y.3
  • 52
    • 55049135859 scopus 로고    scopus 로고
    • MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries
    • Bar M, Wyman SK, Fritz BR, et al.: MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries. Stem Cells 26(10), 2496-2505 (2008).
    • (2008) Stem Cells , vol.26 , Issue.10 , pp. 2496-2505
    • Bar, M.1    Wyman, S.K.2    Fritz, B.R.3
  • 53
    • 41649106136 scopus 로고    scopus 로고
    • Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
    • Morin RD, OConnor MD, Griffith M, et al.: Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res. 18(4), 610-621 (2008).
    • (2008) Genome Res. , vol.18 , Issue.4 , pp. 610-621
    • Morin, R.D.1    Oconnor, M.D.2    Griffith, M.3
  • 55
    • 41849084855 scopus 로고    scopus 로고
    • Discovering microRNAs from deep sequencing data using miRDeep
    • Friedlander MR, Chen W, Adamidi C, et al.: Discovering microRNAs from deep sequencing data using miRDeep. Nat. Biotechnol. 26(4), 407-415 (2008).
    • (2008) Nat. Biotechnol. , vol.26 , Issue.4 , pp. 407-415
    • Friedlander, M.R.1    Chen, W.2    Adamidi, C.3
  • 57
    • 84934437354 scopus 로고    scopus 로고
    • CLIP: Crosslinking and immunoprecipitation of in vivo RNA targets of RNA-binding proteins
    • Jensen KB, Darnell RB: CLIP: crosslinking and immunoprecipitation of in vivo RNA targets of RNA-binding proteins. Methods Mol. Biol. 488, 85-98 (2008).
    • (2008) Methods Mol. Biol. , vol.488 , pp. 85-98
    • Jensen, K.B.1    Darnell, R.B.2
  • 58
    • 56549105330 scopus 로고    scopus 로고
    • HITS-CLIP yields genome-wide insights into brain alternative RNA processing
    • Licatalosi DD, Mele A, Fak JJ, et al.: HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature 456(7221), 464-469 (2008).
    • (2008) Nature , vol.456 , Issue.7221 , pp. 464-469
    • Licatalosi, D.D.1    Mele, A.2    Fak, J.J.3
  • 59
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi SW, Zang JB, Mele A, Darnell RB: Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460(7254), 479-486 (2009).
    • (2009) Nature , vol.460 , Issue.7254 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 60
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3́ untranslated regions and fewer microRNA target sites
    • Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB: Proliferating cells express mRNAs with shortened 3́ untranslated regions and fewer microRNA target sites. Science 320(5883), 1643-1647 (2008).
    • (2008) Science , vol.320 , Issue.5883 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 62
    • 0242266620 scopus 로고    scopus 로고
    • Dicer is essential for mouse development
    • Bernstein E, Kim SY, Carmell MA, et al.: Dicer is essential for mouse development. Nat. Genet. 35(3), 215-217 (2003).
    • (2003) Nat. Genet. , vol.35 , Issue.3 , pp. 215-217
    • Bernstein, E.1    Kim, S.Y.2    Carmell, M.A.3
  • 64
    • 13844294261 scopus 로고    scopus 로고
    • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
    • Kanellopoulou C, Muljo SA, Kung AL, et al.: Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 19(4), 489-501 (2005).
    • (2005) Genes Dev. , vol.19 , Issue.4 , pp. 489-501
    • Kanellopoulou, C.1    Muljo, S.A.2    Kung, A.L.3
  • 65
    • 33847323881 scopus 로고    scopus 로고
    • DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
    • Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R: DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat. Gen. 39(3), 380-385 (2007).
    • (2007) Nat. Gen. , vol.39 , Issue.3 , pp. 380-385
    • Wang, Y.1    Medvid, R.2    Melton, C.3    Jaenisch, R.4    Blelloch, R.5
  • 66
    • 0242266618 scopus 로고    scopus 로고
    • The microRNA-producing enzyme Dicer1 is essential for zebrafish development
    • Wienholds E, Koudijs MJ, van Eeden FJ, Cuppen E, Plasterk RH: The microRNA-producing enzyme Dicer1 is essential for zebrafish development. Nat. Genet. 35(3), 217-218 (2003).
    • (2003) Nat. Genet. , vol.35 , Issue.3 , pp. 217-218
    • Wienholds, E.1    Koudijs, M.J.2    Van Eeden, F.J.3    Cuppen, E.4    Plasterk, R.H.5
  • 67
    • 67649556287 scopus 로고    scopus 로고
    • An elegant mirror: MicroRNAs in stem cells, developmental timing and cancer
    • Nimmo RA, Slack FJ: An elegant mirror: microRNAs in stem cells, developmental timing and cancer. Chromosoma 118(4), 405-418 (2009).
    • (2009) Chromosoma , vol.118 , Issue.4 , pp. 405-418
    • Nimmo, R.A.1    Slack, F.J.2
  • 68
    • 40949100837 scopus 로고    scopus 로고
    • A mammalian microRNA cluster controls DNA methylation and telomere recombination via RBL2-dependent regulation of DNA methyltransferases
    • Benetti R, Gonzalo S, Jaco I, et al.: A mammalian microRNA cluster controls DNA methylation and telomere recombination via RBL2-dependent regulation of DNA methyltransferases. Nat. Struct. Mol. Biol. 15(3), 268-279 (2008).
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , Issue.3 , pp. 268-279
    • Benetti, R.1    Gonzalo, S.2    Jaco, I.3
  • 69
    • 40949130398 scopus 로고    scopus 로고
    • MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
    • Sinkkonen L, Hugenschmidt T, Berninger P, et al.: MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat. Struct. Mol. Biol. 15(3), 259-267 (2008).
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , Issue.3 , pp. 259-267
    • Sinkkonen, L.1    Hugenschmidt, T.2    Berninger, P.3
  • 70
    • 36749013633 scopus 로고    scopus 로고
    • RNA sequence analysis defines Dicers role in mouse embryonic stem cells
    • Calabrese JM, Seila AC, Yeo GW, Sharp PA: RNA sequence analysis defines Dicers role in mouse embryonic stem cells. Proc. Natl Acad. Sci USA 104(46), 18097-18102 (2007).
    • (2007) Proc. Natl Acad. Sci USA , vol.104 , Issue.46 , pp. 18097-18102
    • Calabrese, J.M.1    Seila, A.C.2    Yeo, G.W.3    Sharp, P.A.4
  • 71
    • 2942527400 scopus 로고    scopus 로고
    • Propagation and maintenance of undifferentiated human embryonic stem cells
    • Bodnar MS, Meneses JJ, Rodriguez RT, Firpo MT: Propagation and maintenance of undifferentiated human embryonic stem cells. Stem Cells Dev. 13(3), 243-253 (2004).
    • (2004) Stem Cells Dev. , vol.13 , Issue.3 , pp. 243-253
    • Bodnar, M.S.1    Meneses, J.J.2    Rodriguez, R.T.3    Firpo, M.T.4
  • 72
    • 18844396119 scopus 로고    scopus 로고
    • Embryonic stem cell differentiation: Emergence of a new era in biology and medicine
    • Keller G: Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev. 19(10), 1129-1155 (2005).
    • (2005) Genes Dev. , vol.19 , Issue.10 , pp. 1129-1155
    • Keller, G.1
  • 73
    • 33845315254 scopus 로고    scopus 로고
    • Human embryonic stem cells: A journey beyond cell replacement therapies
    • Menendez P, Bueno C, Wang L: Human embryonic stem cells: a journey beyond cell replacement therapies. Cytotherapy 8(6), 530-541 (2006).
    • (2006) Cytotherapy , vol.8 , Issue.6 , pp. 530-541
    • Menendez, P.1    Bueno, C.2    Wang, L.3
  • 74
    • 76249119007 scopus 로고    scopus 로고
    • Opposing microRNA families regulate self-renewal in mouse embryonic stem cells
    • Melton C, Judson RL, Blelloch R: Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature 463(7281), 621-626 (2010).
    • (2010) Nature , vol.463 , Issue.7281 , pp. 621-626
    • Melton, C.1    Judson, R.L.2    Blelloch, R.3
  • 75
    • 66249139268 scopus 로고    scopus 로고
    • Cell cycle regulation by microRNAs in embryonic stem cells
    • Wang Y, Blelloch R: Cell cycle regulation by microRNAs in embryonic stem cells. Cancer Res. 69(10), 4093-4096 (2009).
    • (2009) Cancer Res. , vol.69 , Issue.10 , pp. 4093-4096
    • Wang, Y.1    Blelloch, R.2
  • 76
    • 37549028759 scopus 로고    scopus 로고
    • MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells
    • Lakshmipathy U, Love B, Goff LA, et al.: MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells. Stem Cells Dev. 16(6), 1003-1016 (2007).
    • (2007) Stem Cells Dev. , vol.16 , Issue.6 , pp. 1003-1016
    • Lakshmipathy, U.1    Love, B.2    Goff, L.A.3
  • 77
    • 33747185122 scopus 로고    scopus 로고
    • Nonrestrictive developmental regulation of microRNA gene expression
    • Strauss WM, Chen C, Lee CT, Ridzon D: Nonrestrictive developmental regulation of microRNA gene expression. Mamm. Genome 17(8), 833-840 (2006).
    • (2006) Mamm. Genome , vol.17 , Issue.8 , pp. 833-840
    • Strauss, W.M.1    Chen, C.2    Lee, C.T.3    Ridzon, D.4
  • 78
    • 48449091318 scopus 로고    scopus 로고
    • Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence
    • Laurent LC, Chen J, Ulitsky I, et al.: Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence. Stem Cells 26(6), 1506-1516 (2008).
    • (2008) Stem Cells , vol.26 , Issue.6 , pp. 1506-1516
    • Laurent, L.C.1    Chen, J.2    Ulitsky, I.3
  • 79
    • 33846933757 scopus 로고    scopus 로고
    • Qualification of embryonal carcinoma 2102EP as a reference for human embryonic stem cell research
    • Josephson R, Ording CJ, Liu Y, et al.: Qualification of embryonal carcinoma 2102EP as a reference for human embryonic stem cell research. Stem Cells 25(2), 437-446 (2007).
    • (2007) Stem Cells , vol.25 , Issue.2 , pp. 437-446
    • Josephson, R.1    Ording, C.J.2    Liu, Y.3
  • 80
    • 34249076321 scopus 로고    scopus 로고
    • The regulation of genes and genomes by small RNAs
    • Ambros V, Chen X: The regulation of genes and genomes by small RNAs. Development 134(9), 1635-1641 (2007).
    • (2007) Development , vol.134 , Issue.9 , pp. 1635-1641
    • Ambros, V.1    Chen, X.2
  • 81
    • 48449084118 scopus 로고    scopus 로고
    • Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
    • Marson A, Levine SS, Cole MF, et al.: Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 134(3), 521-533 (2008).
    • (2008) Cell , vol.134 , Issue.3 , pp. 521-533
    • Marson, A.1    Levine, S.S.2    Cole, M.F.3
  • 82
    • 45849129864 scopus 로고    scopus 로고
    • MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis
    • Hayashi K, Chuva de Sousa Lopes SM, Kaneda M, et al.: MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis. PLoS ONE 3(3), e1738 (2008).
    • (2008) PLoS ONE , vol.3 , Issue.3
    • Hayashi, K.1    Chuva De Sousa Lopes, S.M.2    Kaneda, M.3
  • 83
    • 75349106759 scopus 로고    scopus 로고
    • MicroRNAs: Oncogenes, tumor suppressors or master regulators of cancer heterogeneity?
    • Voorhoeve PM: MicroRNAs: oncogenes, tumor suppressors or master regulators of cancer heterogeneity? Biochim. Biophys. Acta 1805(1), 72-86 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1805 , Issue.1 , pp. 72-86
    • Voorhoeve, P.M.1
  • 84
    • 33646056975 scopus 로고    scopus 로고
    • A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors
    • Voorhoeve PM, le Sage C, Schrier M, et al.: A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 124(6), 1169-1181 (2006).
    • (2006) Cell , vol.124 , Issue.6 , pp. 1169-1181
    • Voorhoeve, P.M.1    Le Sage, C.2    Schrier, M.3
  • 85
    • 34748915836 scopus 로고    scopus 로고
    • Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles
    • Duale N, Lindeman B, Komada M, et al.: Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles. Mol. Cancer 6, 53 (2007).
    • (2007) Mol. Cancer , vol.6 , pp. 53
    • Duale, N.1    Lindeman, B.2    Komada, M.3
  • 86
    • 38849107424 scopus 로고    scopus 로고
    • The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
    • Huang Q, Gumireddy K, Schrier M, et al.: The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat. Cell Biol. 10(2), 202-210 (2008).
    • (2008) Nat. Cell Biol. , vol.10 , Issue.2 , pp. 202-210
    • Huang, Q.1    Gumireddy, K.2    Schrier, M.3
  • 87
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • Landgraf P, Rusu M, Sheridan R, et al.: A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129(7), 1401-1414 (2007).
    • (2007) Cell , vol.129 , Issue.7 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3
  • 88
    • 55449089454 scopus 로고    scopus 로고
    • Embryonic stem cell-specific miR302-367 cluster: Human gene structure and functional characterization of its core promoter
    • Barroso-del Jesus A, Romero-Lopez C, Lucena-Aguilar G, et al.: Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter. Mol. Cell. Biol. 28(21), 6609-6619 (2008).
    • (2008) Mol. Cell. Biol. , vol.28 , Issue.21 , pp. 6609-6619
    • Barroso-Del Jesus, A.1    Romero-Lopez, C.2    Lucena-Aguilar, G.3
  • 89
    • 53549133376 scopus 로고    scopus 로고
    • Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells
    • Card DA, Hebbar PB, Li L, et al.: Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. Mol Cell. Biol. 28(20), 6426-6438 (2008).
    • (2008) Mol Cell. Biol. , vol.28 , Issue.20 , pp. 6426-6438
    • Card, D.A.1    Hebbar, P.B.2    Li, L.3
  • 90
    • 59449100501 scopus 로고    scopus 로고
    • The miR-302-367 cluster as a potential stemness regulator in ESCs
    • Barroso-del Jesus A, Lucena-Aguilar G, Menendez P: The miR-302-367 cluster as a potential stemness regulator in ESCs. Cell Cycle 8(3), 394-398 (2009).
    • (2009) Cell Cycle , vol.8 , Issue.3 , pp. 394-398
    • Barroso-Del Jesus, A.1    Lucena-Aguilar, G.2    Menendez, P.3
  • 91
    • 49749151362 scopus 로고    scopus 로고
    • Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells
    • Gu P, Reid JG, Gao X, et al.: Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells. PLoS ONE 3(7), e2548 (2008).
    • (2008) PLoS ONE , vol.3 , Issue.7
    • Gu, P.1    Reid, J.G.2    Gao, X.3
  • 92
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • Hayashita Y, Osada H, Tatematsu Y, et al.: A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 65(21), 9628-9632 (2005).
    • (2005) Cancer Res. , vol.65 , Issue.21 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3
  • 93
    • 34248398096 scopus 로고    scopus 로고
    • Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells
    • Venturini L, Battmer K, Castoldi M, et al.: Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells. Blood 109(10), 4399-4405 (2007).
    • (2007) Blood , vol.109 , Issue.10 , pp. 4399-4405
    • Venturini, L.1    Battmer, K.2    Castoldi, M.3
  • 94
    • 33749479908 scopus 로고    scopus 로고
    • Downregulation of miR-122 in the rodent and human hepatocellular carcinomas
    • Kutay H, Bai S, Datta J, et al.: Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J. Cell. Biochem. 99(3), 671-678 (2006).
    • (2006) J. Cell. Biochem. , vol.99 , Issue.3 , pp. 671-678
    • Kutay, H.1    Bai, S.2    Datta, J.3
  • 95
    • 34247869960 scopus 로고    scopus 로고
    • Concomitant Myc and microRNA cluster miR-17-92 (C13orf25) amplification in human mantle cell lymphoma
    • Rinaldi A, Poretti G, Kwee I, et al.: Concomitant Myc and microRNA cluster miR-17-92 (C13orf25) amplification in human mantle cell lymphoma. Leuk. Lymphoma 48(2), 410-412 (2007).
    • (2007) Leuk. Lymphoma , vol.48 , Issue.2 , pp. 410-412
    • Rinaldi, A.1    Poretti, G.2    Kwee, I.3
  • 97
    • 37549008310 scopus 로고    scopus 로고
    • Widespread microRNA repression by Myc contributes to tumorigenesis
    • Chang TC, Yu D, Lee YS, et al.: Widespread microRNA repression by Myc contributes to tumorigenesis. Nat. Genet. 40(1), 43-50 (2008).
    • (2008) Nat. Genet. , vol.40 , Issue.1 , pp. 43-50
    • Chang, T.C.1    Yu, D.2    Lee, Y.S.3
  • 98
    • 34047267329 scopus 로고    scopus 로고
    • An E2F/miR-20a autoregulatory feedback loop
    • Sylvestre Y, De Guire V, Querido E, et al.: An E2F/miR-20a autoregulatory feedback loop. J. Biol. Chem. 282(4), 2135-2143 (2007).
    • (2007) J. Biol. Chem. , vol.282 , Issue.4 , pp. 2135-2143
    • Sylvestre, Y.1    De Guire, V.2    Querido, E.3
  • 99
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods K, Thomson JM, Hammond SM: Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J. Biol. Chem. 282(4), 2130-2134 (2007).
    • (2007) J. Biol. Chem. , vol.282 , Issue.4 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 100
    • 0036371956 scopus 로고    scopus 로고
    • Sibling rivalry in the E2F family
    • Trimarchi JM, Lees JA: Sibling rivalry in the E2F family. Nat. Rev. 3(1), 11-20 (2002).
    • (2002) Nat. Rev. , vol.3 , Issue.1 , pp. 11-20
    • Trimarchi, J.M.1    Lees, J.A.2
  • 101
    • 36849078711 scopus 로고    scopus 로고
    • Let-7 regulates self-renewal and tumorigenicity of breast cancer cells
    • Yu F, Yao H, Zhu P, et al.: Let-7 regulates self-renewal and tumorigenicity of breast cancer cells. Cell 131(6), 1109-1123 (2007).
    • (2007) Cell , vol.131 , Issue.6 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3
  • 102
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • Takamizawa J, Konishi H, Yanagisawa K, et al.: Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 64(11), 3753-3756 (2004).
    • (2004) Cancer Res. , vol.64 , Issue.11 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3
  • 103
    • 33646444884 scopus 로고    scopus 로고
    • Let-7 microRNA functions as a potential growth suppressor in human colon cancer cells
    • Akao Y, Nakagawa Y, Naoe T: Let-7 microRNA functions as a potential growth suppressor in human colon cancer cells. Biol. Pharm. Bull. 29(5), 903-906 (2006).
    • (2006) Biol. Pharm. Bull. , vol.29 , Issue.5 , pp. 903-906
    • Akao, Y.1    Nakagawa, Y.2    Naoe, T.3
  • 104
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, et al.: Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl Acad. Sci. USA 101(9), 2999-3004 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , Issue.9 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3
  • 106
    • 34248200155 scopus 로고    scopus 로고
    • MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma
    • Szafranska AE, Davison TS, John J, et al.: MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene 26(30), 4442-4452 (2007).
    • (2007) Oncogene , vol.26 , Issue.30 , pp. 4442-4452
    • Szafranska, A.E.1    Davison, T.S.2    John, J.3
  • 107
    • 42049103216 scopus 로고    scopus 로고
    • The let-7 microRNA reduces tumor growth in mouse models of lung cancer
    • Esquela-Kerscher A, Trang P, Wiggins JF, et al.: The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle 7(6), 759-764 (2008).
    • (2008) Cell Cycle , vol.7 , Issue.6 , pp. 759-764
    • Esquela-Kerscher, A.1    Trang, P.2    Wiggins, J.F.3
  • 108
    • 41649114199 scopus 로고    scopus 로고
    • Suppression of non-small cell lung tumor development by the let-7 microRNA family
    • Kumar MS, Erkeland SJ, Pester RE, et al.: Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc. Natl Acad. Sci. USA 105(10), 3903-3908 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.10 , pp. 3903-3908
    • Kumar, M.S.1    Erkeland, S.J.2    Pester, R.E.3
  • 109
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • Viswanathan SR, Daley GQ, Gregory RI: Selective blockade of microRNA processing by Lin28. Science 320(5872), 97-100 (2008).
    • (2008) Science , vol.320 , Issue.5872 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 110
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising Lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
    • Rybak A, Fuchs H, Smirnova L, et al.: A feedback loop comprising Lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat. Cell Biol. 10(8), 987-993 (2008).
    • (2008) Nat. Cell Biol. , vol.10 , Issue.8 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3
  • 111
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the let-7 precursor loop mediates regulated microRNA processing
    • Newman MA, Thomson JM, Hammond SM: Lin-28 interaction with the let-7 precursor loop mediates regulated microRNA processing. RNA 14(8), 1539-1549 (2008).
    • (2008) RNA , vol.14 , Issue.8 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 112
    • 52049124806 scopus 로고    scopus 로고
    • Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28
    • Piskounova E, Viswanathan SR, Janas M, et al.: Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J. Biol. Chem. 283(31), 21310-21314 (2008).
    • (2008) J. Biol. Chem. , vol.283 , Issue.31 , pp. 21310-21314
    • Piskounova, E.1    Viswanathan, S.R.2    Janas, M.3
  • 113
    • 62549160957 scopus 로고    scopus 로고
    • Lin-28b transactivation is necessary for Myc-mediated let-7 repression and proliferation
    • Chang TC, Zeitels LR, Hwang HW, et al.: Lin-28b transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc. Natl Acad. Sci. USA 106(9), 3384-3389 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.9 , pp. 3384-3389
    • Chang, T.C.1    Zeitels, L.R.2    Hwang, H.W.3
  • 114
    • 20044395613 scopus 로고    scopus 로고
    • Ras is regulated by the let-7 microRNA family
    • Johnson SM, Grosshans H, Shingara J, et al.: Ras is regulated by the let-7 microRNA family. Cell 120(5), 635-647 (2005).
    • (2005) Cell , vol.120 , Issue.5 , pp. 635-647
    • Johnson, S.M.1    Grosshans, H.2    Shingara, J.3
  • 115
    • 34548012848 scopus 로고    scopus 로고
    • The let-7 microRNA represses cell proliferation pathways in human cells
    • Johnson CD, Esquela-Kerscher A, Stefani G, et al.: The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 67(16), 7713-7722 (2007).
    • (2007) Cancer Res. , vol.67 , Issue.16 , pp. 7713-7722
    • Johnson, C.D.1    Esquela-Kerscher, A.2    Stefani, G.3
  • 116
    • 33644875228 scopus 로고    scopus 로고
    • Slowing down the Ras lane: MiRNAs as tumor suppressors?
    • Morris JPT, McManus MT: Slowing down the Ras lane: miRNAs as tumor suppressors? Sci. STKE 2005(297), pe41 (2005).
    • (2005) Sci. STKE , vol.2005 , Issue.297
    • Jpt, M.1    McManus, M.T.2
  • 118
    • 20444440706 scopus 로고    scopus 로고
    • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
    • Lee YS, Kim HK, Chung S, Kim KS, Dutta A: Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation. J. Biol. Chem. 280(17), 16635-16641 (2005).
    • (2005) J. Biol. Chem. , vol.280 , Issue.17 , pp. 16635-16641
    • Lee, Y.S.1    Kim, H.K.2    Chung, S.3    Kim, K.S.4    Dutta, A.5
  • 119
    • 33751571757 scopus 로고    scopus 로고
    • High-level expression of DNA architectural factor HMGA2 and its association with nucleosomes in human embryonic stem cells
    • Li O, Vasudevan D, Davey CA, Droge P: High-level expression of DNA architectural factor HMGA2 and its association with nucleosomes in human embryonic stem cells. Genesis 44(11), 523-529 (2006).
    • (2006) Genesis , vol.44 , Issue.11 , pp. 523-529
    • Li, O.1    Vasudevan, D.2    Davey, C.A.3    Droge, P.4
  • 120
    • 77950357078 scopus 로고    scopus 로고
    • Lin28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro
    • Balzer E, Heine C, Jiang Q, Lee VM, Moss EG: Lin28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro. Development 137(6), 891-900 (2010).
    • (2010) Development , vol.137 , Issue.6 , pp. 891-900
    • Balzer, E.1    Heine, C.2    Jiang, Q.3    Lee, V.M.4    Moss, E.G.5
  • 122
    • 67649222358 scopus 로고    scopus 로고
    • Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
    • Chin M, Mason M, Xie W, et al.: Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell 5(1), 111-123 (2009).
    • (2009) Cell Stem Cell , vol.5 , Issue.1 , pp. 111-123
    • Chin, M.1    Mason, M.2    Xie, W.3
  • 123
    • 56749091922 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
    • Wang Y, Baskerville S, Shenoy A, Babiarz J, Baehner L, Blelloch R: Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat. Genet. 40(12), 1478-1483 (2008).
    • (2008) Nat. Genet. , vol.40 , Issue.12 , pp. 1478-1483
    • Wang, Y.1    Baskerville, S.2    Shenoy, A.3    Babiarz, J.4    Baehner, L.5    Blelloch, R.6
  • 124
    • 84984765621 scopus 로고    scopus 로고
    • Canalization of development by microRNAs
    • Hornstein E, Shomron N: Canalization of development by microRNAs. Nat. Genet. 38(Suppl.), S20-S24 (2006).
    • (2006) Nat. Genet. , vol.38 , Issue.SUPPL.
    • Hornstein, E.1    Shomron, N.2
  • 125
    • 0001579865 scopus 로고
    • Canalization of development and genetic assimilation of acquired characters
    • Waddington CH: Canalization of development and genetic assimilation of acquired characters. Nature 183(4676), 1654-1655 (1959).
    • (1959) Nature , vol.183 , Issue.4676 , pp. 1654-1655
    • Waddington, C.H.1
  • 126
    • 55549108029 scopus 로고    scopus 로고
    • MiR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of cyclin D2 expression
    • Lee NS, Kim JS, Cho WJ, et al.: miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of cyclin D2 expression. Biochem. Biophys. Res. Commun. 377(2), 434-440 (2008).
    • (2008) Biochem. Biophys. Res. Commun. , vol.377 , Issue.2 , pp. 434-440
    • Lee, N.S.1    Kim, J.S.2    Cho, W.J.3
  • 127
    • 67349149082 scopus 로고    scopus 로고
    • MicroRNA-145 regulates Oct4, Sox2, and Klf4 and represses pluripotency in human embryonic stem cells
    • Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS: MicroRNA-145 regulates Oct4, Sox2, and Klf4 and represses pluripotency in human embryonic stem cells. Cell 137(4), 647-658 (2009).
    • (2009) Cell , vol.137 , Issue.4 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3    Thomson, J.A.4    Kosik, K.S.5
  • 128
    • 66149160608 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs promote induced pluripotency
    • Judson RL, Babiarz JE, Venere M, Blelloch R: Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat. Biotechnol. 27(5), 459-461 (2009).
    • (2009) Nat. Biotechnol. , vol.27 , Issue.5 , pp. 459-461
    • Judson, R.L.1    Babiarz, J.E.2    Venere, M.3    Blelloch, R.4
  • 129
    • 52949125268 scopus 로고    scopus 로고
    • MiR-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state
    • Lin SL, Chang DC, Chang-Lin S, et al.: miR-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA 14(10), 2115-2124 (2008).
    • (2008) RNA , vol.14 , Issue.10 , pp. 2115-2124
    • Lin, S.L.1    Chang, D.C.2    Chang-Lin, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.