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Volumn 60, Issue 5, 2003, Pages 871-882

RNA-mediated gene silencing

Author keywords

Chromatin remodelling; Dicer; Post transcriptional gene silencing; RdDM; RISC; SiRNA; StRNA; Systemic RNA silencing

Indexed keywords

DICER; DOUBLE STRANDED RNA; ENDONUCLEASE; ENZYME; MESSENGER RNA; RNA; RNA DERIVATIVE; RNA POLYMERASE; SMALL INTERFERING RNA; SMALL TEMPORAL RNA; UNCLASSIFIED DRUG;

EID: 0038715736     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-2245-2     Document Type: Review
Times cited : (96)

References (111)
  • 1
    • 0037123632 scopus 로고    scopus 로고
    • An expanding universe of non-coding RNAs
    • Storz G. (2002) An expanding universe of non-coding RNAs. Science 296: 1260-1262
    • (2002) Science , vol.296 , pp. 1260-1262
    • Storz, G.1
  • 2
    • 0035195942 scopus 로고    scopus 로고
    • Non-coding RNAs: The architects of eukaryotic complexity
    • Mattick J. S. (2001) Non-coding RNAs: the architects of eukaryotic complexity. EMBO Rep. 2: 989-991
    • (2001) EMBO Rep. , vol.2 , pp. 989-991
    • Mattick, J.S.1
  • 3
    • 0001359591 scopus 로고
    • Introduction of a chalcone synthase gene into Petunia results in reversible co-suppression of homologous genes in trans
    • Napoli C., Lemieux C. and Jorgensen R. (1990) Introduction of a chalcone synthase gene into Petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 2: 279-289
    • (1990) Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 4
    • 0025405838 scopus 로고
    • Flavonoid genes in Petunia: Addition of a limited number of gene copies may lead to a suppression of gene expression
    • Krol A. R. van der, Mur L. A., Beld M., Mol J. N. and Stuitje A. R. (1990) Flavonoid genes in Petunia: addition of a limited number of gene copies may lead to a suppression of gene expression. Plant Cell 2: 291-299
    • (1990) Plant Cell , vol.2 , pp. 291-299
    • Van Der Krol, A.R.1    Mur, L.A.2    Beld, M.3    Mol, J.N.4    Stuitje, A.R.5
  • 5
    • 0025683324 scopus 로고
    • Expression of a truncated tomato polygalacturonase gene inhibits expression of endogenous gene in transgenic plants
    • Smith C. J. S., Watson C. F., Bird C. R., Ray J., Schoch W. and Grierson D. (1990) Expression of a truncated tomato polygalacturonase gene inhibits expression of endogenous gene in transgenic plants. Mol. Gen. Genet. 224: 477-481
    • (1990) Mol. Gen. Genet. , vol.224 , pp. 477-481
    • Smith, C.J.S.1    Watson, C.F.2    Bird, C.R.3    Ray, J.4    Schoch, W.5    Grierson, D.6
  • 6
    • 0029257513 scopus 로고
    • Post-transcriptional co-suppression of β-1,3-glucanase genes does not affect accumulation of transgene nuclear mKNA
    • Carvalho F. de, Niebel F., Frendo P., Van Montagu M. and Cornelissen M. (1995) Post-transcriptional co-suppression of β-1,3-glucanase genes does not affect accumulation of transgene nuclear mKNA. Plant Cell 7: 347-358
    • (1995) Plant Cell , vol.7 , pp. 347-358
    • De Carvalho, F.1    Niebel, F.2    Frendo, P.3    Van Montagu, M.4    Cornelissen, M.5
  • 7
    • 0026441194 scopus 로고
    • Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
    • Romano N. and Macino G. (1992) Quelling: transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Mol. Microbiol. 6: 3343-3353
    • (1992) Mol. Microbiol. , vol.6 , pp. 3343-3353
    • Romano, N.1    Macino, G.2
  • 8
    • 0029934123 scopus 로고    scopus 로고
    • Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation
    • Cogoni C., Irelan J. T., Schumacher M., Schmidhauser T. J., Selker E. U. and Macino G. (1996) Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation. EMBO J. 15: 3153-3163
    • (1996) EMBO J. , vol.15 , pp. 3153-3163
    • Cogoni, C.1    Irelan, J.T.2    Schumacher, M.3    Schmidhauser, T.J.4    Selker, E.U.5    Macino, G.6
  • 9
    • 0029024475 scopus 로고
    • par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • Guo S. and Kemphues K. J. (1995)par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81: 611-620
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 10
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A., Xu S., Montgomery M. K., Kostas S. A., Driver S. E. and Mello C. C. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 11
    • 0033883114 scopus 로고    scopus 로고
    • Heritable gene silencing in Drosophila using double stranded RNA
    • Kennerdell J. R. and Carthew R. W. (2000) Heritable gene silencing in Drosophila using double stranded RNA. Nat. Biotechnol. 17: 896-898
    • (2000) Nat. Biotechnol. , vol.17 , pp. 896-898
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 12
    • 0033573924 scopus 로고    scopus 로고
    • Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): A role for nautilus in embryonic somatic muscle formation
    • Misquitta L. and Paterson B. M. (1999) Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): a role for nautilus in embryonic somatic muscle formation. Proc. Natl. Acad. Sci. USA 96: 1451-1456
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1451-1456
    • Misquitta, L.1    Paterson, B.M.2
  • 13
    • 0032410928 scopus 로고    scopus 로고
    • Double-stranded RNA induces mRNA degradation in Trypanosoma brucei
    • Ngo H., Tschudi C., Gull K. and Ullu E. (1998) Double-stranded RNA induces mRNA degradation in Trypanosoma brucei. Proc. Natl. Acad. Sci. USA 95: 14687-14692
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14687-14692
    • Ngo, H.1    Tschudi, C.2    Gull, K.3    Ullu, E.4
  • 15
    • 0033608994 scopus 로고    scopus 로고
    • Double stranded RNA specifically disrupts gene expression during planarian regeneration
    • Alvarado A. S. and Newmark P. A. (1999) Double stranded RNA specifically disrupts gene expression during planarian regeneration. Proc. Natl. Acad. Sci. USA 96: 5049-5054
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5049-5054
    • Alvarado, A.S.1    Newmark, P.A.2
  • 16
    • 0032506226 scopus 로고    scopus 로고
    • Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA
    • Waterhouse P., Graham M. W. and Wang M. B. (1998) Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA. Proc. Natl. Acad. Sci. USA 95: 13959-13964
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13959-13964
    • Waterhouse, P.1    Graham, M.W.2    Wang, M.B.3
  • 17
    • 0033766888 scopus 로고    scopus 로고
    • Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference
    • Svoboda P., Stein P., Hayashi H. and Schultz R. M. (2000) Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference. Development 127: 4147-4156
    • (2000) Development , vol.127 , pp. 4147-4156
    • Svoboda, P.1    Stein, P.2    Hayashi, H.3    Schultz, R.M.4
  • 18
    • 0033789992 scopus 로고    scopus 로고
    • Specific interference with gene function by double-stranded RNA in early mouse development
    • Wianny F. and Zernicka-Goetz M. (2000) Specific interference with gene function by double-stranded RNA in early mouse development. Nat. Cell Biol. 2: 70-75
    • (2000) Nat. Cell Biol. , vol.2 , pp. 70-75
    • Wianny, F.1    Zernicka-Goetz, M.2
  • 19
    • 0033575910 scopus 로고    scopus 로고
    • Double-stranded RNA induces specific developmental defects in zebrafish embryos
    • Wargelius A., Ellingsen S. and Fjose A. (1999) Double-stranded RNA induces specific developmental defects in zebrafish embryos. Biochem. Biophys. Res. Commun. 263: 156-161
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 156-161
    • Wargelius, A.1    Ellingsen, S.2    Fjose, A.3
  • 20
    • 0034650510 scopus 로고    scopus 로고
    • Double-stranded RNA injection produces null phenotypes in zebrafish
    • erratum 220: 432
    • Li Y. X., Farrell M. J., Liu R., Mohanty N. and Kirby M. L. (2000) Double-stranded RNA injection produces null phenotypes in zebrafish. Dev. Biol. 217: 394-405; (erratum 220: 432)
    • (2000) Dev. Biol. , vol.217 , pp. 394-405
    • Li, Y.X.1    Farrell, M.J.2    Liu, R.3    Mohanty, N.4    Kirby, M.L.5
  • 21
    • 0036529633 scopus 로고    scopus 로고
    • Induction of RNA interference in Caenorhabditis elegans by RNAs derived from plants exhibiting post-transcritional gene silencing
    • Boutla A., Kalantidis K., Tavernarakis N., Tsagris M. and Tablet M. (2002) Induction of RNA interference in Caenorhabditis elegans by RNAs derived from plants exhibiting post-transcritional gene silencing. Nucleic Acids Res. 30: 1688-1694
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1688-1694
    • Boutla, A.1    Kalantidis, K.2    Tavernarakis, N.3    Tsagris, M.4    Tablet, M.5
  • 22
    • 0032080877 scopus 로고    scopus 로고
    • A model for RNA-mediated gene silencing in higher plants
    • Wassenegger M. and Pélissier T. (1998) A model for RNA-mediated gene silencing in higher plants. Plant Mol. Biol. 37: 349-362
    • (1998) Plant Mol. Biol. , vol.37 , pp. 349-362
    • Wassenegger, M.1    Pélissier, T.2
  • 23
    • 0030927776 scopus 로고    scopus 로고
    • Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA
    • Angell S. M. and Baulcombe D. C. (1997) Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA. EMBO J. 16: 3675-3684
    • (1997) EMBO J. , vol.16 , pp. 3675-3684
    • Angell, S.M.1    Baulcombe, D.C.2
  • 24
    • 0027145973 scopus 로고
    • Induction of a highly specific antiviral state in transgenic plants: Implications for regulation of gene expression and virus expression
    • Lindbo J. L., Silva-Rosales L., Proebsting W. M. and Dougherty W. G. (1993) Induction of a highly specific antiviral state in transgenic plants: implications for regulation of gene expression and virus expression. Plant Cell 5: 1749-1759
    • (1993) Plant Cell , vol.5 , pp. 1749-1759
    • Lindbo, J.L.1    Silva-Rosales, L.2    Proebsting, W.M.3    Dougherty, W.G.4
  • 25
    • 3643145804 scopus 로고    scopus 로고
    • Initiation and maintenance of virus-induced gene silencing
    • Ruiz M. T., Voinnet O. and Baulcombe D. C. (1998) Initiation and maintenance of virus-induced gene silencing. Plant Cell 10: 937-946
    • (1998) Plant Cell , vol.10 , pp. 937-946
    • Ruiz, M.T.1    Voinnet, O.2    Baulcombe, D.C.3
  • 26
    • 0032739015 scopus 로고    scopus 로고
    • Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD
    • Ketting R. F., Haverkamp T. H., Luenen H. G. van and Plasterk R. H. (1999) Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell 99: 133-141
    • (1999) Cell , vol.99 , pp. 133-141
    • Ketting, R.F.1    Haverkamp, T.H.2    Van Luenen, H.G.3    Plasterk, R.H.4
  • 27
    • 0032717319 scopus 로고    scopus 로고
    • The rde-1 gene, RNA interference, and transposon silencing in C. elegans
    • Tabara H., Sarkissian M., Kelly W. G., Fleenor J., Grishok A., Timmons L. et al. (1999) The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99: 123-132
    • (1999) Cell , vol.99 , pp. 123-132
    • Tabara, H.1    Sarkissian, M.2    Kelly, W.G.3    Fleenor, J.4    Grishok, A.5    Timmons, L.6
  • 28
    • 0034633770 scopus 로고    scopus 로고
    • AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
    • Fagard M., Boutet S., Morel J.-B., Bellini C. and Vaucheret H. (2000) AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals. Proc. Natl. Acad. Sci. USA 97: 11650-11654
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11650-11654
    • Fagard, M.1    Boutet, S.2    Morel, J.-B.3    Bellini, C.4    Vaucheret, H.5
  • 29
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee R. C., Feinbaum R. I. and Ambros V. (1993)The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 846-854
    • (1993) Cell , vol.75 , pp. 846-854
    • Lee, R.C.1    Feinbaum, R.I.2    Ambros, V.3
  • 30
  • 31
    • 0033551328 scopus 로고    scopus 로고
    • Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase
    • Cogoni C. and Macino G. (1999) Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase. Nature 399: 166-169
    • (1999) Nature , vol.399 , pp. 166-169
    • Cogoni, C.1    Macino, G.2
  • 32
    • 0027298691 scopus 로고
    • RNA-directed RNA polymerase from tomato leaves. 1. Purification and physical properties. II. Catalytic in vitro properties
    • Schiebel W., Haas B., Marinkovic S., Klanner A. and Sänger H. L. (1993). RNA-directed RNA polymerase from tomato leaves. 1. Purification and physical properties. II. Catalytic in vitro properties. J. Biol. Chem. 268: 11851-11867
    • (1993) J. Biol. Chem. , vol.268 , pp. 11851-11867
    • Schiebel, W.1    Haas, B.2    Marinkovic, S.3    Klanner, A.4    Sänger, H.L.5
  • 33
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E., Caudy A. C., Hammond S. M. and Hannon G. J. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363-366
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.C.2    Hammond, S.M.3    Hannon, G.J.4
  • 34
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in posttranscriptional gene silencing in plants
    • Hamilton A. J. and Baulcombe D. C. (1999) A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 286: 950-952
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.J.1    Baulcombe, D.C.2
  • 35
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cell extracts
    • Hammond S. M., Bernstein E., Beach D. and Hannon G. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cell extracts. Nature 404: 293-296
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.4
  • 36
  • 37
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore P., Tuschl T., Sharp P. and Bartel D. (2000) RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101: 25-33
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.1    Tuschl, T.2    Sharp, P.3    Bartel, D.4
  • 38
    • 0034724519 scopus 로고    scopus 로고
    • Double-stranded RNA as a template for gene silencing
    • Bass B. L. (2000) Double-stranded RNA as a template for gene silencing. Cell 101: 235-238
    • (2000) Cell , vol.101 , pp. 235-238
    • Bass, B.L.1
  • 39
    • 0034708215 scopus 로고    scopus 로고
    • EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans
    • Smardon A., Spoerke J., Stacey S., Klein M., Mackin N. and Maine E. (2000) EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans. Curr. Biol. 10: 169-178
    • (2000) Curr. Biol. , vol.10 , pp. 169-178
    • Smardon, A.1    Spoerke, J.2    Stacey, S.3    Klein, M.4    Mackin, N.5    Maine, E.6
  • 40
    • 0034716907 scopus 로고    scopus 로고
    • Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance
    • Mourrain E, Béclin C., Elmayan T., Feuerbach F., Godon C., Morel J.-B. et al. (2000) Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance. Cell 101: 533-542
    • (2000) Cell , vol.101 , pp. 533-542
    • Mourrain, E.1    Béclin, C.2    Elmayan, T.3    Feuerbach, F.4    Godon, C.5    Morel, J.-B.6
  • 41
    • 0034716924 scopus 로고    scopus 로고
    • An RNA-dependent RNA polymerase gene in Arahidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus
    • Dalmay T, Hamilton A., Rudd S, Angell S. and Baulcombe D. C. (2000) An RNA-dependent RNA polymerase gene in Arahidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus. Cen 101: 543-553
    • (2000) Cen , vol.101 , pp. 543-553
    • Dalmay, T.1    Hamilton, A.2    Rudd, S.3    Angell, S.4    Baulcombe, D.C.5
  • 42
    • 0035900651 scopus 로고    scopus 로고
    • On the role of RNA amplification in dsRNA-triggered gene silencing
    • Sijen T., Fleenor J., Simmer F., Thijssen K. L., Parrish S., Timmons L. et al. (2001) On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 107: 465-476
    • (2001) Cell , vol.107 , pp. 465-476
    • Sijen, T.1    Fleenor, J.2    Simmer, F.3    Thijssen, K.L.4    Parrish, S.5    Timmons, L.6
  • 43
    • 0033669621 scopus 로고    scopus 로고
    • Post-transcriptional gene silencing across kingdoms
    • Cogoni C. and Macino G. (2000) Post-transcriptional gene silencing across kingdoms. Curr. Opin. Genet. Dev. 10: 638-643
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 638-643
    • Cogoni, C.1    Macino, G.2
  • 44
    • 0035160923 scopus 로고    scopus 로고
    • RNA interference in Trypanosoma brucei: Cloning of small interfering RNAs provides evidence for retroposon-derived 24-26 nt RNAs
    • Djikeng A., Shi H., Tschudi C. and Ullu E. (2001) RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposon-derived 24-26 nt RNAs. RNA 7: 1-9
    • (2001) RNA , vol.7 , pp. 1-9
    • Djikeng, A.1    Shi, H.2    Tschudi, C.3    Ullu, E.4
  • 45
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNASs) induce sequence-specific silencing in mammalian cells
    • Paddison P. J., Candy A. A., Bernstein E., Hannon G. J. and Conklin D. S. (2002) Short hairpin RNAs (shRNASs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16: 948-958
    • (2002) Genes Dev. , vol.16 , pp. 948-958
    • Paddison, P.J.1    Candy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 46
    • 0035798399 scopus 로고    scopus 로고
    • RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs
    • Lipardi C., Wei Q. and Paterson B. M. (2001) RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs. Cell 107: 297-307
    • (2001) Cell , vol.107 , pp. 297-307
    • Lipardi, C.1    Wei, Q.2    Paterson, B.M.3
  • 47
    • 0037169034 scopus 로고    scopus 로고
    • RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs
    • Tijsterman M., Ketting R. F., Okihara K. L., Sijen T. and Plasterk R. H. A. (2002) RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs. Science 295: 694-696
    • (2002) Science , vol.295 , pp. 694-696
    • Tijsterman, M.1    Ketting, R.F.2    Okihara, K.L.3    Sijen, T.4    Plasterk, R.H.A.5
  • 48
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir S. M., Lendeckel W. and Tuschl T. (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15: 188-200
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 49
    • 0037089135 scopus 로고    scopus 로고
    • Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor
    • Holen T, Amarzguioui M., Wilger M. T., Babaie E. and Prydz H. (2002) Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Res. 30: 1757-1766
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1757-1766
    • Holen, T.1    Amarzguioui, M.2    Wilger, M.T.3    Babaie, E.4    Prydz, H.5
  • 50
    • 0035691993 scopus 로고    scopus 로고
    • Thirty-three years later, a glimpse at the ribonuclease II1 active site
    • Zamore P. D. (2001) Thirty-three years later, a glimpse at the ribonuclease II1 active site. Mol. Cell 8: 1158-1160
    • (2001) Mol. Cell , vol.8 , pp. 1158-1160
    • Zamore, P.D.1
  • 51
    • 0035798415 scopus 로고    scopus 로고
    • ATP requirements and small interfering RNA structure in the RNA interference pathway
    • Nykänen A., Haley B. and Zamore P. D. (2001) ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107: 309-321
    • (2001) Cell , vol.107 , pp. 309-321
    • Nykänen, A.1    Haley, B.2    Zamore, P.D.3
  • 52
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C elegans
    • Ketting R. F,. Fischer S. E., Bernstein E., Sijen T., Harmon G. J. and Plasterk R. H. (2001) Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C elegans. Genes Dev. 15: 2654-2659
    • (2001) Genes Dev. , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Harmon, G.J.5    Plasterk, R.H.6
  • 53
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok A., Pasquinelli A. E., Conte D., Li N., Parrish S., Ha I. et al. (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106: 23-34
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6
  • 54
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvágner G, McLachlan J., Pasquinelli A. E., Bálint É., Tuschl T. and Zamore P. D. (2001) A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293: 834-838
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvágner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Bálint, É.4    Tuschl, T.5    Zamore, P.D.6
  • 55
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
    • Pasquinelli A. E., Reinhart Stack F., Martindale M. Q., Kurodall M. I., Mallor B. et al. (2000) Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408: 86-89
    • (2000) Nature , vol.408 , pp. 86-89
    • Pasquinelli, A.E.1    Reinhart Stack, F.2    Martindale, M.Q.3    Kurodall, M.I.4    Mallor, B.5
  • 56
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee R. C. and Ambros V. (2001) An extensive class of small RNAs in Caenorhabditis elegans. Science 294: 862-864
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 57
    • 0035984059 scopus 로고    scopus 로고
    • Endogenous and silencing-associated small RNAs in plants
    • Llave C., Kasschau K. D., Rector M. A. and Carrington J. C. (2002) Endogenous and silencing-associated small RNAs in plants. Plant Cell 14: 1605-1619
    • (2002) Plant Cell , vol.14 , pp. 1605-1619
    • Llave, C.1    Kasschau, K.D.2    Rector, M.A.3    Carrington, J.C.4
  • 58
    • 0033634682 scopus 로고    scopus 로고
    • Functional anatomy of a dsRNA trigger: Differential requirement for the two trigger strands in RNA interference
    • Parrish S., Fleenor J., Xu S., Mello C. and Fire A. (2000) Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference. Mol. Cell 6: 1077-1087
    • (2000) Mol. Cell , vol.6 , pp. 1077-1087
    • Parrish, S.1    Fleenor, J.2    Xu, S.3    Mello, C.4    Fire, A.5
  • 59
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • Hammond S., Boettcher S., Caudy A., Kobayashi R. and Hannon G. J. (2001) Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293: 1146-1150
    • (2001) Science , vol.293 , pp. 1146-1150
    • Hammond, S.1    Boettcher, S.2    Caudy, A.3    Kobayashi, R.4    Hannon, G.J.5
  • 60
    • 0032472373 scopus 로고    scopus 로고
    • AGO1 defines a novel locus of Arabidopsis controlling leaf development
    • Bohmert K., Camus I., Bellini, C., Bouchez D., Caboche M. and Benning C. (1998) AGO1 defines a novel locus of Arabidopsis controlling leaf development. EMBO J. 17: 170-180
    • (1998) EMBO J. , vol.17 , pp. 170-180
    • Bohmert, K.1    Camus, I.2    Bellini, C.3    Bouchez, D.4    Caboche, M.5    Benning, C.6
  • 61
    • 0034737747 scopus 로고    scopus 로고
    • Genetic requirements for inheritance of RNAi in C. elegans
    • Grishok A., Tabara H. and Mello C. (2000) Genetic requirements for inheritance of RNAi in C. elegans Science 287: 2494-2497
    • (2000) Science , vol.287 , pp. 2494-2497
    • Grishok, A.1    Tabara, H.2    Mello, C.3
  • 62
    • 0035043250 scopus 로고    scopus 로고
    • Developmental roles and molecular characterisation of a Drosophila homologue of Arabidopsis argonaute I, the founder of a novel superfamily
    • Kataoka Y., Takeichi M. and Uemura T. (2001) Developmental roles and molecular characterisation of a Drosophila homologue of Arabidopsis argonaute I, the founder of a novel superfamily. Genes Cells 6: 313-141
    • (2001) Genes Cells , vol.6 , pp. 313-141
    • Kataoka, Y.1    Takeichi, M.2    Uemura, T.3
  • 63
    • 0032443562 scopus 로고    scopus 로고
    • A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal
    • Cox D. N., Chao A., Baker J., Chang L., Qiao D. and Lin H. (1998) A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev. 12: 3715-3727
    • (1998) Genes Dev. , vol.12 , pp. 3715-3727
    • Cox, D.N.1    Chao, A.2    Baker, J.3    Chang, L.4    Qiao, D.5    Lin, H.6
  • 64
    • 0032955004 scopus 로고    scopus 로고
    • Genetic and molecular characterization of sting, a gene involved in crystal formation and meiotic drive in the male germ line of Drosophila melanogaster
    • Schmidt A., Palumbo G., Bozzetti M. P., Tritto P., Pimpinelli S. and Schäfer U. (1998) Genetic and molecular characterization of sting, a gene involved in crystal formation and meiotic drive in the male germ line of Drosophila melanogaster. Genetics 151: 749-760
    • (1998) Genetics , vol.151 , pp. 749-760
    • Schmidt, A.1    Palumbo, G.2    Bozzetti, M.P.3    Tritto, P.4    Pimpinelli, S.5    Schäfer, U.6
  • 65
    • 0342804533 scopus 로고    scopus 로고
    • Transcription: Gene silencing in worms and fungi
    • Catalanotto C., Azzalin G., Macino G. and Cogoni C. (2000) Transcription: gene silencing in worms and fungi. Nature 404: 245
    • (2000) Nature , vol.404 , pp. 245
    • Catalanotto, C.1    Azzalin, G.2    Macino, G.3    Cogoni, C.4
  • 66
    • 0036205131 scopus 로고    scopus 로고
    • Involvement of small RNAs and role of the qde genes in the gene silencing pathway in Neurospora
    • Catalanotto C., Azzalin G., Macino G. and Cogoni C. (2002) Involvement of small RNAs and role of the qde genes in the gene silencing pathway in Neurospora. Genes Dev. 16: 790-795
    • (2002) Genes Dev. , vol.16 , pp. 790-795
    • Catalanotto, C.1    Azzalin, G.2    Macino, G.3    Cogoni, C.4
  • 67
    • 0034306266 scopus 로고    scopus 로고
    • Domains in gene silencing and cell differentiation proteins: The novel PAZ domain and redefinition of the Piwi domain
    • Cerutti L., Mian N. and Bateman A. (2000) Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the Piwi domain. Trends Biochem. Sci.. 10: 481-482
    • (2000) Trends Biochem. Sci. , vol.10 , pp. 481-482
    • Cerutti, L.1    Mian, N.2    Bateman, A.3
  • 68
    • 0035905760 scopus 로고    scopus 로고
    • Diced defence
    • Baulcombe D. (2001) Diced defence. Nature 409: 295-296
    • (2001) Nature , vol.409 , pp. 295-296
    • Baulcombe, D.1
  • 69
    • 0035859929 scopus 로고    scopus 로고
    • Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
    • Caplen N. J., Parrish S., Imafu F., Fire A. and Morgan R. A. (2001) Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. USA 98: 9742-9747
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9742-9747
    • Caplen, N.J.1    Parrish, S.2    Imafu, F.3    Fire, A.4    Morgan, R.A.5
  • 70
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir S. M., Martinez J., Patkaniowska A., Lendeckel W. and Tuschl T. (2001) Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 3: 6877-6888
    • (2001) EMBO J. , vol.3 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 71
    • 0036529570 scopus 로고    scopus 로고
    • Post-transcriptional suppression of gene expression in Xenopus embryos by small interfering RNA
    • Zhou Y., Ching Y. P., Kok K. H., Kung H. F. and Jin D. Y. (2002) Post-transcriptional suppression of gene expression in Xenopus embryos by small interfering RNA. Nucleic Acids Res. 30: 1664-1669
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1664-1669
    • Zhou, Y.1    Ching, Y.P.2    Kok, K.H.3    Kung, H.F.4    Jin, D.Y.5
  • 72
    • 0034609759 scopus 로고    scopus 로고
    • Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos
    • Yang D, Lu H. and Erickson J. W. (2000) Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos. Curr. Biol. 10: 1191-1200
    • (2000) Curr. Biol. , vol.10 , pp. 1191-1200
    • Yang, D.1    Lu, H.2    Erickson, J.W.3
  • 73
    • 0035901497 scopus 로고    scopus 로고
    • SDE3 encodes an RNA helicase required for posttranscriptional gene silencing in Arabidopsis
    • Dalmay T., Horsefield R., Braunstein T. H. and Baulcombe D. C. (2001) SDE3 encodes an RNA helicase required for posttranscriptional gene silencing in Arabidopsis. EMBO J. 20: 2069-2078
    • (2001) EMBO J. , vol.20 , pp. 2069-2078
    • Dalmay, T.1    Horsefield, R.2    Braunstein, T.H.3    Baulcombe, D.C.4
  • 74
    • 0034665818 scopus 로고    scopus 로고
    • A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans
    • Domeier M. E., Morse D. P., Knight S. W., Portereiko M., Bass B. L. and Mango S. E. (2000) A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans. Science 289: 1928-1931
    • (2000) Science , vol.289 , pp. 1928-1931
    • Domeier, M.E.1    Morse, D.P.2    Knight, S.W.3    Portereiko, M.4    Bass, B.L.5    Mango, S.E.6
  • 75
    • 0034634360 scopus 로고    scopus 로고
    • Transgene and transposon silencing in Chlamydomonas reinhardtii by a DEAH-Box RNA helicase
    • Wu-Scharf D., Jeong B., Zhang C. and Cerutti H. (2000) Transgene and transposon silencing in Chlamydomonas reinhardtii by a DEAH-Box RNA helicase. Science 290: 1159-1163
    • (2000) Science , vol.290 , pp. 1159-1163
    • Wu-Scharf, D.1    Jeong, B.2    Zhang, C.3    Cerutti, H.4
  • 76
    • 0034757613 scopus 로고    scopus 로고
    • Distinct roles for RDE1 and RDE4 during RNA interference in Caenorhabditis elegans
    • Parrish S. and Fire A. (2001) Distinct roles for RDE1 and RDE4 during RNA interference in Caenorhabditis elegans. RNA 7: 1397-1402
    • (2001) RNA , vol.7 , pp. 1397-1402
    • Parrish, S.1    Fire, A.2
  • 77
    • 0037188904 scopus 로고    scopus 로고
    • The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-Box helicase to direct RNAi in C. elegans
    • Tabara H., Yigit E., Siomi H. and Mello C. C. (2002) The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-Box helicase to direct RNAi in C. elegans. Cell 109: 861-871
    • (2002) Cell , vol.109 , pp. 861-871
    • Tabara, H.1    Yigit, E.2    Siomi, H.3    Mello, C.C.4
  • 78
    • 0028031830 scopus 로고
    • RNA-directed de novo methylation of genomic sequences in plants
    • Wassenegger M., Heimes S., Riedel L. and Sanger H. L. (1994). RNA-directed de novo methylation of genomic sequences in plants. Cell 76: 567-576
    • (1994) Cell , vol.76 , pp. 567-576
    • Wassenegger, M.1    Heimes, S.2    Riedel, L.3    Sanger, H.L.4
  • 79
  • 80
    • 0142039054 scopus 로고    scopus 로고
    • A target of 30 bp is sufficient for RNA-directed DNA methylation
    • Pélissier T. and Wassenegger M. (2000) A target of 30 bp is sufficient for RNA-directed DNA methylation. RNA 6: 55-65
    • (2000) RNA , vol.6 , pp. 55-65
    • Pélissier, T.1    Wassenegger, M.2
  • 81
    • 0034596989 scopus 로고    scopus 로고
    • Transcriptional silencing and promoter methylation triggered by double-stranded RNA
    • Metre M. F., Aufsatz W., Winden J. van der, Matzke M. A. and Matzke A. J. M. (2000) Transcriptional silencing and promoter methylation triggered by double-stranded RNA. EMBO J. 19: 5194-5201
    • (2000) EMBO J. , vol.19 , pp. 5194-5201
    • Metre, M.F.1    Aufsatz, W.2    Van Der Winden, J.3    Matzke, M.A.4    Matzke, A.J.M.5
  • 82
    • 0035873992 scopus 로고    scopus 로고
    • RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA thgger and requires Met 1 for maintenance
    • Jones L., Ratcliff F. and Baulcombe D. C. (2001) RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA thgger and requires Met 1 for maintenance. Curr. Biol. 11: 747-757
    • (2001) Curr. Biol. , vol.11 , pp. 747-757
    • Jones, L.1    Ratcliff, F.2    Baulcombe, D.C.3
  • 83
    • 0035039978 scopus 로고    scopus 로고
    • Replicating satellite RNA induces sequence-specific DNA methylation and truncated transcripts in plants
    • Wang M. B., Wesley S. V., Finnegan E. J., Smith N. A. and Waterhouse P. M. (2001) Replicating satellite RNA induces sequence-specific DNA methylation and truncated transcripts in plants. RNA 7: 16-28
    • (2001) RNA , vol.7 , pp. 16-28
    • Wang, M.B.1    Wesley, S.V.2    Finnegan, E.J.3    Smith, N.A.4    Waterhouse, P.M.5
  • 85
    • 0034699391 scopus 로고    scopus 로고
    • Chromodomains are protein-RNA interaction modules
    • Akhtar A., Zink D. and Beaker, P. B. (2000) Chromodomains are protein-RNA interaction modules. Nature 407: 405
    • (2000) Nature , vol.407 , pp. 405
    • Akhtar, A.1    Zink, D.2    Beaker, P.B.3
  • 86
    • 0030835456 scopus 로고    scopus 로고
    • Cosuppression in Drosophila: Gene silencing of alcohol dehydrogenase by white-Adh transgenes is policomb dependent
    • Pal-Bhadra M., Bhadra U. and Bitchier J. A. (1997). Cosuppression in Drosophila: gene silencing of alcohol dehydrogenase by white-Adh transgenes is policomb dependent. Cell 90: 479-490
    • (1997) Cell , vol.90 , pp. 479-490
    • Pal-Bhadra, M.1    Bhadra, U.2    Bitchier, J.A.3
  • 87
    • 0033215511 scopus 로고    scopus 로고
    • Cosuppression of non-homologous transgenes in Drosophila involves mutually related endogenous sequences
    • Pal-Bhadra M., Bhadra U. and Birchler J. A. (1999). Cosuppression of non-homologous transgenes in Drosophila involves mutually related endogenous sequences. Cell 99: 35-46
    • (1999) Cell , vol.99 , pp. 35-46
    • Pal-Bhadra, M.1    Bhadra, U.2    Birchler, J.A.3
  • 88
    • 0035838369 scopus 로고    scopus 로고
    • Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline
    • Aravin A. A., Naumova N. M., Tulin A. V., Vagin V. V., Rozovsky Y. M. and Gvozdev V. A. (2001) Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline. Curr. Biol. 11: 1017-1027
    • (2001) Curr. Biol. , vol.11 , pp. 1017-1027
    • Aravin, A.A.1    Naumova, N.M.2    Tulin, A.V.3    Vagin, V.V.4    Rozovsky, Y.M.5    Gvozdev, V.A.6
  • 89
    • 0037007007 scopus 로고    scopus 로고
    • Using RNA interference to identify genes required for RNA interference
    • Dudley N. R., Labbe J. C. and Goldstein B. (2002) Using RNA interference to identify genes required for RNA interference. Proc. Natl. Acad. Sci. USA 99: 4191-4196
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 4191-4196
    • Dudley, N.R.1    Labbe, J.C.2    Goldstein, B.3
  • 90
    • 0034649547 scopus 로고    scopus 로고
    • DNA methylation and chromatin structure mutants affect both post-transcriptional and transcriptional gene silencing in Arabidopsis
    • Morel J-B., Mourrain P, Béclin C. and Vaucheret H. (2001) DNA methylation and chromatin structure mutants affect both post-transcriptional and transcriptional gene silencing in Arabidopsis. Curr. Biol. 10: 1591-1594
    • (2001) Curr. Biol. , vol.10 , pp. 1591-1594
    • Morel, J.-B.1    Mourrain, P.2    Béclin, C.3    Vaucheret, H.4
  • 92
    • 0342679989 scopus 로고    scopus 로고
    • Drug-induced hypomethylation of a posttranscriptionally silenced transgene locus of tobacco leads to partial release of silencing
    • Kovarik A., Van Houdt H., Holy A. and Depicker A. (2000) Drug-induced hypomethylation of a posttranscriptionally silenced transgene locus of tobacco leads to partial release of silencing. FEBS Lett. 467: 47-51
    • (2000) FEBS Lett. , vol.467 , pp. 47-51
    • Kovarik, A.1    Van Houdt, H.2    Holy, A.3    Depicker, A.4
  • 94
    • 0035059524 scopus 로고    scopus 로고
    • HC-pro suppression of transgene silencing eliminates the small RNAs but not transgene methylation or the mobile signal
    • Mallory A., Ely L., Smith T. H., Marathe R., Anandalakshmi R., Fagard M. et al. (2001) HC-pro suppression of transgene silencing eliminates the small RNAs but not transgene methylation or the mobile signal. Plant Cell 13: 571-583
    • (2001) Plant Cell , vol.13 , pp. 571-583
    • Mallory, A.1    Ely, L.2    Smith, T.H.3    Marathe, R.4    Anandalakshmi, R.5    Fagard, M.6
  • 95
    • 0034613277 scopus 로고    scopus 로고
    • A calmodulin related protein that suppresses post-transcriptional gene silencing in plants
    • Anandalakshmi R., Marathe R., Ge X., Herr J. M. Jr, Mau C., Mallory A. et al. (2000) A calmodulin related protein that suppresses post-transcriptional gene silencing in plants. Science 290: 142-144
    • (2000) Science , vol.290 , pp. 142-144
    • Anandalakshmi, R.1    Marathe, R.2    Ge, X.3    Herr J.M., Jr.4    Mau, C.5    Mallory, A.6
  • 96
    • 0032538794 scopus 로고    scopus 로고
    • Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana
    • Brigneti G, Voinnet O., Li W. X., Ji L. H., Ding S. W. and Baulcombe D. C. (1998) Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana. EMBO J. 17: 6739-6746
    • (1998) EMBO J , vol.17 , pp. 6739-6746
    • Brigneti, G.1    Voinnet, O.2    Li, W.X.3    Ji, L.H.4    Ding, S.W.5    Baulcombe, D.C.6
  • 97
    • 0034599462 scopus 로고    scopus 로고
    • Suppression of post-transcriptional gene silencing by a plant viral protein localized in the nucleus
    • Lucy A. P., Guo H. S., Li W. X. and Ding S. W. (2000) Suppression of post-transcriptional gene silencing by a plant viral protein localized in the nucleus. EMBO J. 19: 1672-1680
    • (2000) EMBO J. , vol.19 , pp. 1672-1680
    • Lucy, A.P.1    Guo, H.S.2    Li, W.X.3    Ding, S.W.4
  • 98
    • 0037123630 scopus 로고    scopus 로고
    • Induction and suppression of RNA silencing by an animal virus
    • Li H., Li W. X. and Ding S. W. (2002) Induction and suppression of RNA silencing by an animal virus. Science 296: 1319-1321
    • (2002) Science , vol.296 , pp. 1319-1321
    • Li, H.1    Li, W.X.2    Ding, S.W.3
  • 99
    • 0034730318 scopus 로고    scopus 로고
    • A viral movement protein prevents spread of the gene silencing signal in Nicotiana benthamiana
    • Voinnet O., Lederer C. and Baulcombe D. C. (2000) A viral movement protein prevents spread of the gene silencing signal in Nicotiana benthamiana. Cell 103: 157-167
    • (2000) Cell , vol.103 , pp. 157-167
    • Voinnet, O.1    Lederer, C.2    Baulcombe, D.C.3
  • 100
    • 0037124354 scopus 로고    scopus 로고
    • A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs
    • Silhavy D., Molnar A., Lucioli A., Szittya G., Hornyik C., Tavazza M. et al. (2002) A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs. EMBO J. 21: 3070-3080
    • (2002) EMBO J. , vol.21 , pp. 3070-3080
    • Silhavy, D.1    Molnar, A.2    Lucioli, A.3    Szittya, G.4    Hornyik, C.5    Tavazza, M.6
  • 101
    • 0030875953 scopus 로고    scopus 로고
    • Systemic acquired silencing: Transgene-specific posttranscriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions
    • erratum 17: 2137
    • Palauqui J. C., Elmayan T., Pollien J. M. and Vaucheret, H. (1998) Systemic acquired silencing: transgene-specific posttranscriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. EMBO J. 16: 4738-4745 (erratum 17: 2137)
    • (1998) EMBO J. , vol.16 , pp. 4738-4745
    • Palauqui, J.C.1    Elmayan, T.2    Pollien, J.M.3    Vaucheret, H.4
  • 102
    • 0032538348 scopus 로고    scopus 로고
    • Systemic spread of sequence-specific transgene RNA degradation in plants is initiated by localized introduction of ectopic promoterless DNA
    • Voinnet O., Vain P., Angell S. and Baulcombe D. C. (1998) Systemic spread of sequence-specific transgene RNA degradation in plants is initiated by localized introduction of ectopic promoterless DNA. Cell 95: 177-187
    • (1998) Cell , vol.95 , pp. 177-187
    • Voinnet, O.1    Vain, P.2    Angell, S.3    Baulcombe, D.C.4
  • 104
    • 0035195264 scopus 로고    scopus 로고
    • Characteristics of post-transcriptional gene silencing
    • Chicas A. and Macino G. (2001) Characteristics of post-transcriptional gene silencing. EMBO Rep. 2: 992-996
    • (2001) EMBO Rep. , vol.2 , pp. 992-996
    • Chicas, A.1    Macino, G.2
  • 105
    • 0032578911 scopus 로고    scopus 로고
    • Specific interference by ingested dsRNA
    • Timmons L. and Fire A. (2000) Specific interference by ingested dsRNA. Nature 395: 854
    • (2000) Nature , vol.395 , pp. 854
    • Timmons, L.1    Fire, A.2
  • 106
    • 0037192490 scopus 로고    scopus 로고
    • Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1
    • Winston W. M., Molodowitch and Hunter C. P. (2002) Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science 295: 2456-2459
    • (2002) Science , vol.295 , pp. 2456-2459
    • Winston, W.M.1    Molodowitch2    Hunter, C.P.3
  • 107
    • 0033027913 scopus 로고    scopus 로고
    • The PINHEAD/ZWILLE gene acts pleiotropically in Arabidopsis development and has overlapping functions with the ARGONAUTE1 gene
    • Lynn K., Fernandez A., Aida M., Sedbrook J., Tasaka M., Masson P. et al. (1999) The PINHEAD/ZWILLE gene acts pleiotropically in Arabidopsis development and has overlapping functions with the ARGONAUTE1 gene. Development 126: 469-481
    • (1999) Development , vol.126 , pp. 469-481
    • Lynn, K.1    Fernandez, A.2    Aida, M.3    Sedbrook, J.4    Tasaka, M.5    Masson, P.6
  • 108
    • 0033385170 scopus 로고    scopus 로고
    • Disruption of an RNA helicase/RNase III gene in Arabidopsis causes unregulated cell division in floral meristems
    • Jacobsen S. E., Running M. P. and Meyerowitz E. M. (1999) Disruption of an RNA helicase/RNase III gene in Arabidopsis causes unregulated cell division in floral meristems. Development 126: 5231-5243
    • (1999) Development , vol.126 , pp. 5231-5243
    • Jacobsen, S.E.1    Running, M.P.2    Meyerowitz, E.M.3
  • 109
    • 0033979493 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel human gene (HERNA) which encodes a putative RNA-helicase
    • Matsuda S., Ichigotani Y., Okuda T., Irimura T., Nakatsugawa S. and Hamaguchi M. (2000) Molecular cloning and characterization of a novel human gene (HERNA) which encodes a putative RNA-helicase. Biochim. Biophys. Acta 1490: 163-169
    • (2000) Biochim. Biophys. Acta , vol.1490 , pp. 163-169
    • Matsuda, S.1    Ichigotani, Y.2    Okuda, T.3    Irimura, T.4    Nakatsugawa, S.5    Hamaguchi, M.6
  • 110
    • 0033579344 scopus 로고    scopus 로고
    • Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase
    • Cogoni C. and Macino G. (1999) Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase. Science 286: 2342-2344
    • (1999) Science , vol.286 , pp. 2342-2344
    • Cogoni, C.1    Macino, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.