Antibody affinity maturation in vitro using unconjugated peptide antigen

Protein Engineering, Design and Selection

Volumn 23, Issue 4, 2010, Pages 185-193

  Iwai, Hiroto ^a   Öztürk, Bengü ^a,b   Ihara, Masaki ^a,c   Ueda, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

^c SHINSHU UNIVERSITY   (Japan)

Author keywords

affinity maturation; antibody library; hapten; open sandwich selection; phage display

Indexed keywords

AFFINITY MATURATION; ANTIBODY LIBRARY; HAPTEN; OPEN SANDWICH SELECTION; PHAGE DISPLAY;

ANTIGENS; BINDERS; BINDING ENERGY; ENGINEERING EXHIBITIONS; MOLECULES; PEPTIDES;

ANTIBODIES;

ANTIGEN; C PEPTIDE; OSTEOCALCIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; PEPTIDE; PEPTIDE LIBRARY;

ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VITRO STUDY; MATURATION; MUTAGENESIS; MUTANT; NONHUMAN; PHAGE DISPLAY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PROTEIN ENGINEERING;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIGENS; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES; POLYMERASE CHAIN REACTION; PROTEIN ENGINEERING;

EID: 77954648005     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzp093     Document Type: Article

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