Inhibitory effect on protein kinase CΘ by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes

European Journal of Pharmacology

Volumn 642, Issue 1-3, 2010, Pages 47-55

  Yang, Lina ^a   Qian, Zhiyu ^a   Ji, Hui ^a   Yang, Ruhui ^a   Wang, Yuhuan ^a   Xi, Liang ^a   Sheng, Liang ^a   Zhao, Bohua ^a   Zhang, Xiaoming ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Crocetin; IKK ; Insulin insensitivity; JNK; PKC

Indexed keywords

CROCETIN; GLUCOSE; I KAPPA B KINASE BETA; I KAPPA B KINASE INHIBITOR; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PALMITIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C THETA; SERINE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; CAROTENOID; DEOXYGLUCOSE; I KAPPA B KINASE; INSULIN RECEPTOR SUBSTRATE; ISOENZYME; PALMITIC ACID DERIVATIVE; PRKCQ PROTEIN, MOUSE; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; GLUCOSE METABOLISM; INHIBITION KINETICS; INSULIN RESISTANCE; INSULIN SENSITIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; 3T3 CELL LINE; ADIPOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; INFLAMMATION; METABOLISM; PHOSPHORYLATION; TRANSPORT AT THE CELLULAR LEVEL;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; BIOLOGICAL TRANSPORT; CAROTENOIDS; DEOXYGLUCOSE; ENZYME ACTIVATION; GLUCOSE; I-KAPPA B KINASE; INFLAMMATION; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; ISOENZYMES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; PALMITATES; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; SERINE; SIGNAL TRANSDUCTION;

EID: 77954624162     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.05.061     Document Type: Article

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