Plaque deposition dependent decrease in 5-HT2A serotonin receptor in aβPPswe/PS1dE9 amyloid overexpressing mice

Journal of Alzheimer's Disease

Volumn 20, Issue 4, 2010, Pages 1201-1213

  Holm, Peter ^a   Ettrup, Anders ^a   Klein, Anders B ^a   Santini, Martin A ^a   El Sayed, Mona ^a   Elvang, Anders B ^b   Stensbøl, Tine B ^b   Mikkelsen, Jens D ^a   Knudsen, Gitte M ^a   Aznar, Susana ^a  

^a Rigshospitalet   (Denmark)

^b H LUNDBECK A S   (Denmark)

Author keywords

Alzheimer's disease; amyloid ; frontoparietal cortex; hippocampus; prefrontal cortex; receptor functionality; serotonin receptor; somatosensory cortex; transgenic mice

Indexed keywords

4 IODO 2,5 DIMETHOXYAMPHETAMINE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; CARBON 11; ESCITALOPRAM; MESSENGER RNA; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER; VOLINANSERIN; 2-(4'-(METHYLAMINO)PHENYL)-6-HYDROXYBENZOTHIAZOLE; 4-IODO-2,5-DIMETHOXYPHENYLISOPROPYLAMINE; AMPHETAMINE DERIVATIVE; ANILINE DERIVATIVE; CITALOPRAM; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; FLUOROBENZENE; PIPERIDINE DERIVATIVE; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN UPTAKE INHIBITOR; THIAZOLE DERIVATIVE;

AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN FUNCTION; BRAIN PARIETOFRONTAL CORTEX; BRAIN REGION; CONTROLLED STUDY; FRONTAL CORTEX; GENE EXPRESSION; GENE OVEREXPRESSION; GROUPS BY AGE; HEAD TWITCH; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MALE; MOUSE; NONHUMAN; ONCOGENE C FOS; PARIETAL LOBE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RECEPTOR BINDING; SENILE PLAQUE; SEROTONINERGIC SYSTEM; SOMATOSENSORY CORTEX; AGING; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; GENETICS; HEAD MOVEMENT; HUMAN; ONCOGENE; PATHOLOGY; PHYSIOLOGY; STATISTICAL ANALYSIS; TRANSGENIC MOUSE;

AGING; AMPHETAMINES; AMYLOID BETA-PROTEIN PRECURSOR; ANILINE COMPOUNDS; ANIMALS; AUTORADIOGRAPHY; CITALOPRAM; DATA INTERPRETATION, STATISTICAL; FLUOROBENZENES; GENES, FOS; HEAD MOVEMENTS; HUMANS; IN SITU HYBRIDIZATION; INDICATORS AND REAGENTS; MALE; MICE; MICE, TRANSGENIC; PIPERIDINES; PLAQUE, AMYLOID; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN ANTAGONISTS; SEROTONIN RECEPTOR AGONISTS; SEROTONIN UPTAKE INHIBITORS; THIAZOLES;

EID: 77954559762     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-100117     Document Type: Article

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