-
1
-
-
0035689651
-
Behavioral assessment of Alzheimer's transgenic mice following long-term Aβ vaccination: Task specificity and correlations between Aβ and spatial memory
-
G.W. Arendash, M.N. Gordon, D.M. Diamond, L.A. Austin, J.M. Hatcher, G. DiCarlo, D. Wilcock, and D. Morgan Behavioral assessment of Alzheimer's transgenic mice following long-term Aβ vaccination: task specificity and correlations between Aβ and spatial memory DNA Cell Biol. 20 2001 737 744
-
(2001)
DNA Cell Biol.
, vol.20
, pp. 737-744
-
-
Arendash, G.W.1
Gordon, M.N.2
Diamond, D.M.3
Austin, L.A.4
Hatcher, J.M.5
Dicarlo, G.6
Wilcock, D.7
Morgan, D.8
-
2
-
-
0035830686
-
Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
-
G.W. Arendash, D.L. King, M.N. Gordon, D. Morgan, J.M. Hatcher, C.E. Hope, and D.M. Diamond Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes Brain Res. 891 2001 42 53
-
(2001)
Brain Res.
, vol.891
, pp. 42-53
-
-
Arendash, G.W.1
King, D.L.2
Gordon, M.N.3
Morgan, D.4
Hatcher, J.M.5
Hope, C.E.6
Diamond, D.M.7
-
3
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
D.R. Borchelt, T. Ratovitski, J. van Lare, M.K. Lee, V. Gonzales, N.A. Jenkins, D.L. Price, and S.S. Sisodia Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins Neuron 19 1997 939 945
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Price, D.L.7
Sisodia, S.S.8
-
4
-
-
0033358671
-
Early-onset autosomal dominant Alzheimer disease: Prevalence, genetic heterogeneity, and mutation spectrum
-
D. Campion, C. Dumanchin, D. Hannequin, B. Dubois, S. Bellliard, M. Puel, C. Thomas-Anerion, A. Michon, C. Martin, F. Charbonnier, G. Raux, A. Camuzat, C. Penet, V. Mesnage, M. Martinez, F. Clerget-Darpoux, A. Brice, and T. Frebourg Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum Am. J. Hum. Genet. 65 1999 664 670
-
(1999)
Am. J. Hum. Genet.
, vol.65
, pp. 664-670
-
-
Campion, D.1
Dumanchin, C.2
Hannequin, D.3
Dubois, B.4
Bellliard, S.5
Puel, M.6
Thomas-Anerion, C.7
Michon, A.8
Martin, C.9
Charbonnier, F.10
Raux, G.11
Camuzat, A.12
Penet, C.13
Mesnage, V.14
Martinez, M.15
Clerget-Darpoux, F.16
Brice, A.17
Frebourg, T.18
-
5
-
-
0034700480
-
A learning deficit related to age and β-amyloid plaques in a mouse model of Alzheimer's disease
-
G. Chen, K.S. Chen, J. Knox, J. Inglis, A. Bernard, S.J. Martin, A. Justice, L. McConlogue, D. Games, S.B. Freedman, and R.G.M. Morris A learning deficit related to age and β-amyloid plaques in a mouse model of Alzheimer's disease Nature 408 2000 975 979
-
(2000)
Nature
, vol.408
, pp. 975-979
-
-
Chen, G.1
Chen, K.S.2
Knox, J.3
Inglis, J.4
Bernard, A.5
Martin, S.J.6
Justice, A.7
McConlogue, L.8
Games, D.9
Freedman, S.B.10
Morris, R.G.M.11
-
6
-
-
0035877756
-
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid protein 695
-
M.A. Chishti, D.-S. Yang, C. Janus, A.L. Phinney, P. Horne, J. Pearson, R. Strome, N. Zuker, J. Loukides, J. French, S. Turner, G. Lozza, M. Grilli, S. Kunicki, C. Morissette, J. Paquette, F. Gervais, C. Bergeron, P.E. Fraser, G.A. Carlson, P.St. George-Hyslop, and D. Westaway Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid protein 695 J. Biol. Chem. 276 2001 21562 21570
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.-S.2
Janus, C.3
Phinney, A.L.4
Horne, P.5
Pearson, J.6
Strome, R.7
Zuker, N.8
Loukides, J.9
French, J.10
Turner, S.11
Lozza, G.12
Grilli, M.13
Kunicki, S.14
Morissette, C.15
Paquette, J.16
Gervais, F.17
Bergeron, C.18
Fraser, P.E.19
Carlson, G.A.20
George-Hyslop, P.St.21
Westaway, D.22
more..
-
7
-
-
0034980307
-
A detailed ethological analysis of the mouse open field test: Effects of diazepam, chlordiazepoxide and an extremely low frequency pulsed magnetic field
-
E. Choleris, A.W. Thomas, M. Kavaliers, and F.S. Prato A detailed ethological analysis of the mouse open field test: effects of diazepam, chlordiazepoxide and an extremely low frequency pulsed magnetic field Neurosci. Biobehav. Rev. 25 2001 235 260
-
(2001)
Neurosci. Biobehav. Rev.
, vol.25
, pp. 235-260
-
-
Choleris, E.1
Thomas, A.W.2
Kavaliers, M.3
Prato, F.S.4
-
8
-
-
0034523749
-
Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease
-
J.A. Chung, and J.L. Cummings Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease Neurol. Clin. 18 2000 829 846
-
(2000)
Neurol. Clin.
, vol.18
, pp. 829-846
-
-
Chung, J.A.1
Cummings, J.L.2
-
9
-
-
0033056242
-
Behavioral syndromes in Alzheimer's disease: Description and correlates
-
G.B. Frisoni, L. Rozzini, A. Gozetti, G. Binetti, O. Zanetti, A. Bianchetti, M. Trabucchi, and J.L. Cummings Behavioral syndromes in Alzheimer's disease: description and correlates Dement. Geriatr. Cogn. Disord. 10 1999 130 138
-
(1999)
Dement. Geriatr. Cogn. Disord.
, vol.10
, pp. 130-138
-
-
Frisoni, G.B.1
Rozzini, L.2
Gozetti, A.3
Binetti, G.4
Zanetti, O.5
Bianchetti, A.6
Trabucchi, M.7
Cummings, J.L.8
-
10
-
-
0347125212
-
Distinctive cognitive profiles in Alzheimer's disease and subcortical vascular dementia
-
N.L. Graham, T. Emery, and J.R. Hodges Distinctive cognitive profiles in Alzheimer's disease and subcortical vascular dementia J. Neurol. Neurosurg. Psychiatry 75 2004 61 71
-
(2004)
J. Neurol. Neurosurg. Psychiatry
, vol.75
, pp. 61-71
-
-
Graham, N.L.1
Emery, T.2
Hodges, J.R.3
-
11
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin transgenes
-
L.A. Holcomb, M.N. Gordon, E. McGowan, X. Yu, S. Benkovic, P. Jantzen, K. Wright, I. Saad, R. Mueller, D. Morgan, S. Sanders, C. Zehr, K. O'Campo, J. Hardy, C.-M. Prada, C. Eckman, S. Younkin, K. Hsiao, and K. Duff Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin transgenes Nat. Med. 4 1998 97 100
-
(1998)
Nat. Med.
, vol.4
, pp. 97-100
-
-
Holcomb, L.A.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.-M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
12
-
-
0032756213
-
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: Lack of association with amyloid deposits
-
L.A. Holcomb, M.N. Gordon, P. Jantzen, K. Hsaio, K. Duff, and D. Morgan Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits Behav. Genet. 29 1999 177 185
-
(1999)
Behav. Genet.
, vol.29
, pp. 177-185
-
-
Holcomb, L.A.1
Gordon, M.N.2
Jantzen, P.3
Hsaio, K.4
Duff, K.5
Morgan, D.6
-
13
-
-
0032744697
-
Influence of spatial and temporal manipulations on the anxiolytic efficacy of chlordiazepoxide in mice previously exposed to the elevated plus-maze
-
A. Holmes, and R.J. Rodgers Influence of spatial and temporal manipulations on the anxiolytic efficacy of chlordiazepoxide in mice previously exposed to the elevated plus-maze Neurosci. Biobehav. Rev. 23 1999 971 980
-
(1999)
Neurosci. Biobehav. Rev.
, vol.23
, pp. 971-980
-
-
Holmes, A.1
Rodgers, R.J.2
-
14
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
K. Hsiao, P. Chapman, S. Nilsen, C. Eckman, Y. Harigaya, S. Younkin, F. Yang, and G. Cole Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice Science 274 1996 99 102
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
15
-
-
0029058934
-
Neuropsychological detection and characterization of preclinical Alzheimer's disease
-
D.M. Jacobs, M. Sano, G. Dooneief, K. Marder, K.L. Bell, and Y. Stern Neuropsychological detection and characterization of preclinical Alzheimer's disease Neurology 45 1995 957 962
-
(1995)
Neurology
, vol.45
, pp. 957-962
-
-
Jacobs, D.M.1
Sano, M.2
Dooneief, G.3
Marder, K.4
Bell, K.L.5
Stern, Y.6
-
16
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: Evidence for augmentation of a 42-specific γ secretase
-
J.L. Jankowsky, D.J. Fadale, J. Anderson, G.M. Xu, V. Gonzales, N.A. Jenkins, N.G. Copeland, M.K. Lee, L.H. Younkin, S.L. Wagner, S.G. Younkin, and D.R. Borchelt Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase Hum. Mol. Genet. 13 2004 159 170
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Lee, M.K.8
Younkin, L.H.9
Wagner, S.L.10
Younkin, S.G.11
Borchelt, D.R.12
-
17
-
-
0034700471
-
Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
C. Janus, J. Pearson, J. McLaurin, P.M. Matthews, Y. Jiang, S.D. Schmidt, M.A. Chishti, P. Horne, D. Heslin, J. French, H.T.J. Mount, R.A. Nixon, M. Mercken, C. Bergeron, P.E. Fraser, P.St. George-Hyslop, and D. Westaway Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease Nature 408 2000 979 982
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Matthews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Horne, P.8
Heslin, D.9
French, J.10
Mount, H.T.J.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
George-Hyslop, P.St.16
Westaway, D.17
-
18
-
-
0037088956
-
Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months
-
D.L. King, and G.W. Arendash Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months Physiol. Behav. 75 2002 627 642
-
(2002)
Physiol. Behav.
, vol.75
, pp. 627-642
-
-
King, D.L.1
Arendash, G.W.2
-
19
-
-
0036161518
-
The neurobiological basis of spontaneous alternation
-
R. Lalonde The neurobiological basis of spontaneous alternation Neurosci. Biobehav. Rev. 26 2002 91 104
-
(2002)
Neurosci. Biobehav. Rev.
, vol.26
, pp. 91-104
-
-
Lalonde, R.1
-
20
-
-
4644335036
-
Exploratory activity, anxiety, and motor coordination in bigenic APPswe + PS1/ΔE9 mice
-
R. Lalonde, H.-D. Kim, and K. Fukuchi Exploratory activity, anxiety, and motor coordination in bigenic APPswe + PS1/ΔE9 mice Neurosci. Lett. 369 2004 156 161
-
(2004)
Neurosci. Lett.
, vol.369
, pp. 156-161
-
-
Lalonde, R.1
Kim, H.-D.2
Fukuchi, K.3
-
21
-
-
0037159635
-
Spatial learning, exploration, anxiety, and motor coordination in female APP23 transgenic mice with the Swedish mutation
-
R. Lalonde, M. Dumont, M. Staufenbiel, C. Sturchler-Pierrat, and C. Strazielle Spatial learning, exploration, anxiety, and motor coordination in female APP23 transgenic mice with the Swedish mutation Brain Res. 956 2002 36 44
-
(2002)
Brain Res.
, vol.956
, pp. 36-44
-
-
Lalonde, R.1
Dumont, M.2
Staufenbiel, M.3
Sturchler-Pierrat, C.4
Strazielle, C.5
-
22
-
-
0038022595
-
695SWE mutation: Effects on exploratory activity, anxiety, and motor coordination
-
695SWE mutation: effects on exploratory activity, anxiety, and motor coordination Brain Res. 977 2003 38 45
-
(2003)
Brain Res.
, vol.977
, pp. 38-45
-
-
Lalonde, R.1
Lewis, T.L.2
Strazielle, C.3
Kim, H.4
Fukuchi, K.5
-
23
-
-
0036174969
-
The effects of long-term treatment with metrifonate, a cholinesterase inhibitor, on cholinergic activity, amyloid pathology, and cognitive function in APP and PS1 doubly transgenic mice
-
L. Liu, S. Ikonen, T. Heikkinen, T. Tapiola, T. van Groen, and H. Tanila The effects of long-term treatment with metrifonate, a cholinesterase inhibitor, on cholinergic activity, amyloid pathology, and cognitive function in APP and PS1 doubly transgenic mice Exp. Neurol. 173 2002 196 204
-
(2002)
Exp. Neurol.
, vol.173
, pp. 196-204
-
-
Liu, L.1
Ikonen, S.2
Heikkinen, T.3
Tapiola, T.4
Van Groen, T.5
Tanila, H.6
-
24
-
-
0037118879
-
Elevated levels of Aβ1-40 and Aβ1-42 do not alter the binding sites of nicotinic receptor subtypes in the brain of APPswe and PS1 double transgenic mice
-
A. Marutle, C. Unger, E. Hellström-Lindahl, J. Wang, J. Puoliväli, H. Tanila, A. Nordberg, and X. Zhang Elevated levels of Aβ1-40 and Aβ1-42 do not alter the binding sites of nicotinic receptor subtypes in the brain of APPswe and PS1 double transgenic mice Neurosci. Lett. 328 2002 269 272
-
(2002)
Neurosci. Lett.
, vol.328
, pp. 269-272
-
-
Marutle, A.1
Unger, C.2
Hellström-Lindahl, E.3
Wang, J.4
Puoliväli, J.5
Tanila, H.6
Nordberg, A.7
Zhang, X.8
-
25
-
-
0033525520
-
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain
-
D. Moechars, I. Dewachter, K. Lorent, D. Reversé, V. Baekelandt, A. Naidu, I. Tesseur, K. Spittaels, C. Van Den Haute, F. Checler, E. Godaux, B. Cordell, and F. Van Leuven Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain J. Biol. Chem. 274 1999 6483 6492
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6483-6492
-
-
Moechars, D.1
Dewachter, I.2
Lorent, K.3
Reversé, D.4
Baekelandt, V.5
Naidu, A.6
Tesseur, I.7
Spittaels, K.8
Van Den Haute, C.9
Checler, F.10
Godaux, E.11
Cordell, B.12
Van Leuven, F.13
-
26
-
-
0029055738
-
Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human β-amyloid protein precursor protein
-
P.M. Moran, L.S. Higgins, B. Cordell, and P.C. Moser Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human β-amyloid protein precursor protein Proc. Natl. Acad. Sci. U.S.A. 92 1995 5341 5345
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 5341-5345
-
-
Moran, P.M.1
Higgins, L.S.2
Cordell, B.3
Moser, P.C.4
-
27
-
-
0019957779
-
Place navigation impaired in rats with hippocampal lesions
-
R.G.M. Morris, P. Garrud, J.N.P. Rawlins, and J. O'Keefe Place navigation impaired in rats with hippocampal lesions Nature 292 1982 681 683
-
(1982)
Nature
, vol.292
, pp. 681-683
-
-
Morris, R.G.M.1
Garrud, P.2
Rawlins, J.N.P.3
O'Keefe, J.4
-
28
-
-
0042924399
-
Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits
-
J.J. Palop, B. Jones, L. Kekonius, J. Chin, G.Q. Yu, J. Raber, E. Masliah, and L. Mucke Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits Proc. Natl. Acad. Sci. U.S.A. 100 2003 9572 9577
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 9572-9577
-
-
Palop, J.J.1
Jones, B.2
Kekonius, L.3
Chin, J.4
Yu, G.Q.5
Raber, J.6
Masliah, E.7
Mucke, L.8
-
29
-
-
0036235633
-
Hippocampal Aβ42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice
-
J. Puoliväli, J. Wang, T. Heikkinen, M. Heikkilä, T. Tapiola, T. van Groen, and H. Tanila Hippocampal Aβ42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice Neurobiol. Dis. 9 2002 339 347
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 339-347
-
-
Puoliväli, J.1
Wang, J.2
Heikkinen, T.3
Heikkilä, M.4
Tapiola, T.5
Van Groen, T.6
Tanila, H.7
-
30
-
-
0036132592
-
Performances of patients with a dementia of the Alzheimer type in the Standardized Road-Map test of Direction Sense
-
C. Rainville, N. Marchand, and R. Passini Performances of patients with a dementia of the Alzheimer type in the Standardized Road-Map test of Direction Sense Neuropsychologia 40 2002 567 573
-
(2002)
Neuropsychologia
, vol.40
, pp. 567-573
-
-
Rainville, C.1
Marchand, N.2
Passini, R.3
-
31
-
-
10744230072
-
Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease
-
J.C. Richardson, C.E. Kendal, R. Anderson, F. Priest, E. Gower, P. Soden, R. Gray, S. Topps, D.R. Howlett, D. Lavender, N.J. Clarke, J.C. Barnes, R. Haworth, M.G. Stewart, and H.T.R. Rupniak Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease Neuroscience 122 2003 213 228
-
(2003)
Neuroscience
, vol.122
, pp. 213-228
-
-
Richardson, J.C.1
Kendal, C.E.2
Anderson, R.3
Priest, F.4
Gower, E.5
Soden, P.6
Gray, R.7
Topps, S.8
Howlett, D.R.9
Lavender, D.10
Clarke, N.J.11
Barnes, J.C.12
Haworth, R.13
Stewart, M.G.14
Rupniak, H.T.R.15
-
32
-
-
0032886820
-
Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains
-
D.C. Rogers, D.N. Jones, P.R. Nelson, C.M. Jones, C.A. Quilter, T.L. Robinson, and J.J. Hagan Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains Behav. Brain Res. 105 1999 207 217
-
(1999)
Behav. Brain Res.
, vol.105
, pp. 207-217
-
-
Rogers, D.C.1
Jones, D.N.2
Nelson, P.R.3
Jones, C.M.4
Quilter, C.A.5
Robinson, T.L.6
Hagan, J.J.7
-
34
-
-
0037266894
-
Age-dependent cognitive decline in the APP23 model precedes amyloid deposition
-
D. Van Dam, R. D'Hooge, M. Staufenbiel, C. Van Ginneken, F. Van Meir, and P.P. De Dyn Age-dependent cognitive decline in the APP23 model precedes amyloid deposition Eur. J. Neurosci. 17 2003 388 396
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 388-396
-
-
Van Dam, D.1
D'Hooge, R.2
Staufenbiel, M.3
Van Ginneken, C.4
Van Meir, F.5
De Dyn, P.P.6
|