메뉴 건너뛰기




Volumn 132, Issue 5, 2009, Pages 1310-1323

Episodic memory loss is related to hippocampal-mediated β-amyloid deposition in elderly subjects

Author keywords

amyloid; Hippocampus; Magnetic resonance imaging; Pittsburgh Compound B; Preclinical Alzheimers disease

Indexed keywords

AMYLOID BETA PROTEIN;

EID: 66549127860     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awn320     Document Type: Article
Times cited : (601)

References (70)
  • 1
    • 55949117032 scopus 로고    scopus 로고
    • Amyloid deposition is frequent and often is not associated with signi?cant cognitive impairment in the elderly
    • Aizenstein HJ, Nebes RD, Saxton JA, Price JC, Mathis CA, Tsopelas ND, et al. Amyloid deposition is frequent and often is not associated with signi?cant cognitive impairment in the elderly. Arch Neurol 2008; 65: 1509-17
    • (2008) Arch Neurol , vol.65 , pp. 1509-1517
    • Aizenstein, H.J.1    Nebes, R.D.2    Saxton, J.A.3    Price, J.C.4    Mathis, C.A.5    Tsopelas, N.D.6
  • 2
    • 33646418394 scopus 로고    scopus 로고
    • Conversion of mild cognitive impairment to Alzheimer disease predicted by hippocampal atrophy maps
    • Apostolova LG, Dutton RA, Dinov ID, Hayashi KM, Toga AW, Cummings JL, et al. Conversion of mild cognitive impairment to Alzheimer disease predicted by hippocampal atrophy maps. Arch Neurol 2006; 63: 693-9
    • (2006) Arch Neurol , vol.63 , pp. 693-699
    • Apostolova, L.G.1    Dutton, R.A.2    Dinov, I.D.3    Hayashi, K.M.4    Toga, A.W.5    Cummings, J.L.6
  • 3
    • 0025717816 scopus 로고
    • The topographical and neuroanatomical distribution of neuro?brillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease
    • Arnold SE, Hyman BT, Flory J, Damasio AR, Van Hoesen GW. The topographical and neuroanatomical distribution of neuro?brillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cereb Cortex 1991; 1: 103-16
    • (1991) Cereb Cortex , vol.1 , pp. 103-116
    • Arnold, S.E.1    Hyman, B.T.2    Flory, J.3    Damasio, A.R.4    Van Hoesen, G.W.5
  • 4
    • 0023020183 scopus 로고
    • The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations
    • Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol 1986; 51: 1173-82
    • (1986) J Pers Soc Psychol , vol.51 , pp. 1173-1182
    • Baron, R.M.1    Kenny, D.A.2
  • 5
    • 33745876233 scopus 로고    scopus 로고
    • Neuropathology of older persons without cognitive impairment from two community-based studies
    • DOI 10.1212/01.wnl.0000219668.47116.e6, PII 0000611420060627000014
    • Bennett DA, Schneider JA, Arvanitakis Z, Kelly JF, Aggarwal NT, Shah RC, et al. Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology 2006; 66: 1837-44. (Pubitemid 44049813)
    • (2006) Neurology , vol.66 , Issue.12 , pp. 1837-1844
    • Bennett, D.A.1    Schneider, J.A.2    Arvanitakis, Z.3    Kelly, J.F.4    Aggarwal, N.T.5    Shah, R.C.6    Wilson, R.S.7
  • 6
    • 1542268242 scopus 로고    scopus 로고
    • Neuro?brillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function
    • Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE. Neuro?brillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. Arch Neurol 2004; 61: 378-84. (Pubitemid 38327357)
    • (2004) Arch Neurol , vol.61 , pp. 378-84
    • Bennett, D.A.1    Schneider, J.A.2    Wilson, R.S.3    Bienias, J.L.4    Arnold, S.E.5
  • 7
    • 0025863618 scopus 로고
    • Neuropathological stageing of alzheimer-related changes
    • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991; 82: 239-59
    • (1991) Acta Neuropathol , vol.82 , pp. 239-59
    • Braak, H.1    Braak, E.2
  • 8
    • 0030805991 scopus 로고    scopus 로고
    • Frequency of stages of Alzheimer-related lesions in different age categories
    • DOI 10.1016/S0197-4580(97)00056-0, PII S0197458097000560
    • Braak H, Braak E. Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol Aging 1997; 18: 351-7 (Pubitemid 27435070)
    • (1997) Neurobiology of Aging , vol.18 , Issue.4 , pp. 351-357
    • Braak, H.1    Braak, E.2
  • 9
    • 5644271407 scopus 로고    scopus 로고
    • A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization:reliability and validation against manual measurement of total intracranial volume
    • Buckner RL, Head D, Parker J, Fotenos AF, Marcus D, Morris JC, et al. A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume. Neuroimage 2004; 23: 724-38 (Pubitemid 39370623)
    • (2004) Neuroimage , vol.23 , pp. 724-38
    • Buckner, R.L.1    Head, D.2    Parker, J.3    Fotenos, A.F.4    Marcus, D.5    Morris, J.C.6
  • 10
    • 0032769093 scopus 로고    scopus 로고
    • Cortical surface-based analysis I. Segmentation and surface reconstruction
    • Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 1999; 9: 179-94
    • (1999) Neuroimage , vol.9 , pp. 179-94
    • Dale, A.M.1    Fischl, B.2    Sereno, M.I.3
  • 15
    • 33644832047 scopus 로고    scopus 로고
    • Inverse relation between in vivo amyloid imaging load and cerebrosp-inal fluid Abeta42 in humans
    • Fagan AM, Mintun MA, Mach RH, Lee SY, Dence CS, Shah AR, et al. Inverse relation between in vivo amyloid imaging load and cerebrosp-inal ?uid Abeta42 in humans. Ann Neurol 2006; 59: 512-9 (Pubitemid 43358072)
    • (2006) Ann Neurol , vol.59 , pp. 512-9
    • Fagan, A.M.1    Mintun, M.A.2    MacH, R.H.3    Lee, S.Y.4    Dence, C.S.5    Shah, A.R.6
  • 16
    • 0034744999 scopus 로고    scopus 로고
    • Automated manifold surgery: Constructing geometrically accurate and topologically correct models of the human cerebral cortex
    • DOI 10.1109/42.906426, PII S0278006201007960
    • Fischl B, Liu A, Dale AM. Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex. IEEE Trans Med Imaging 2001; 20: 70-80. (Pubitemid 32293421)
    • (2001) IEEE Transactions on Medical Imaging , vol.20 , Issue.1 , pp. 70-80
    • Fischl, B.1    Liu, A.2    Dale, A.M.3
  • 17
    • 18244406829 scopus 로고    scopus 로고
    • Whole brain segmentation:automated labeling of neuroanatomical structures in the human brain
    • Fischl B, Salat DH, Busa E, Albert M, Dieterich M, Haselgrove C, et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 2002; 33: 341-55 (Pubitemid 34162530)
    • (2002) Neuron , vol.33 , pp. 341-55
    • Fischl, B.1    Salat, D.H.2    Busa, E.3    Albert, M.4    Dieterich, M.5    Haselgrove, C.6
  • 19
    • 38349081521 scopus 로고    scopus 로고
    • Brain volume decline in aging:evidence for a relation between socioeco-nomic status, preclinical Alzheimer disease, and reserve
    • Fotenos AF, Mintun MA, Snyder AZ, Morris JC, Buckner RL. Brain volume decline in aging: evidence for a relation between socioeco-nomic status, preclinical Alzheimer disease, and reserve. Arch Neurol 2008; 65: 113-120
    • (2008) Arch Neurol , vol.65 , pp. 113-20
    • Fotenos, A.F.1    Mintun, M.A.2    Snyder, A.Z.3    Morris, J.C.4    Buckner, R.L.5
  • 21
    • 1842427969 scopus 로고    scopus 로고
    • Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI
    • Greicius MD, Srivastava G, Reiss AL, Menon V. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci USA 2004; 101: 4637-42 (Pubitemid 38437463)
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4637-42
    • Greicius, M.D.1    Srivastava, G.2    Reiss, A.L.3    Menon, V.4
  • 23
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Pro-gress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: pro-gress and problems on the road to therapeutics. Science 2002; 297: 353-6 (Pubitemid 34790756)
    • (2002) Science , vol.297 , pp. 353-6
    • Hardy, J.1    Selkoe, D.J.2
  • 24
    • 0031593785 scopus 로고    scopus 로고
    • Newropathological and neuropsychological changes in 'normal' aging:evidence for preclinical Alzheimer disease in cognitively normal individuals
    • Hulette CM, Welsh-Bohmer KA, Murray MG, Saunders AM, Mash DC, McIntyre LM. Neuropathological and neuropsychological changes in 'normal' aging: evidence for preclinical Alzheimer disease in cognitively normal individuals. J Neuropathol Exp Neurol 1998; 57: 1168-74 (Pubitemid 28562746)
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 1168-74
    • Hulette, C.M.1    Welsh-Bohmer, K.A.2    Murray, M.G.3    Saunders, A.M.4    Mash, D.C.5    McIntyre, L.M.6
  • 27
    • 39749108812 scopus 로고    scopus 로고
    • 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment
    • Jack CR Jr, Lowe VJ, Senjem ML, Weigand SD, Kemp BJ, Shiung MM, et al. 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain 2008b; 131: 665-80
    • (2008) Brain , vol.131 , pp. 665-80
    • Jack Jr., C.R.1    Lowe, V.J.2    Senjem, M.L.3    Weigand, S.D.4    Kemp, B.J.5    Shiung, M.M.6
  • 28
    • 0344889207 scopus 로고    scopus 로고
    • Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment
    • Jack CR Jr, Petersen RC, Xu YC, O'Brien PC, Smith GE, Ivnik RJ, et al. Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment. Neurology 1999; 52: 1397-1403 (Pubitemid 29190530)
    • (1999) Neurology , vol.52 , pp. 1397-403
    • Jack Jr., C.R.1    Petersen, R.C.2    Xu, Y.C.3    O'Brien, P.C.4    Smith, G.E.5    Ivnik, R.J.6
  • 29
    • 33646437238 scopus 로고    scopus 로고
    • Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia
    • Jicha GA, Parisi JE, Dickson DW, Johnson K, Cha R, Ivnik RJ, et al. Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia. Arch Neurol 2006; 63: 674-81
    • (2006) Arch Neurol , vol.63 , pp. 674-81
    • Jicha, G.A.1    Parisi, J.E.2    Dickson, D.W.3    Johnson, K.4    Cha, R.5    Ivnik, R.J.6
  • 30
    • 0023905906 scopus 로고
    • Clinical, pathological, and neurochemical changes in dementia: A sub-group with preserved mental status and numerous neocortical plaques
    • Katzman R, Terry R, DeTeresa R, Brown T, Davies P, Fuld P, et al. Clinical, pathological, and neurochemical changes in dementia: a sub-group with preserved mental status and numerous neocortical plaques. Ann Neurol 1988; 23: 138-44 (Pubitemid 18081451)
    • (1988) Ann Neurol , vol.23 , pp. 138-44
    • Katzman, R.1    Terry, R.2    Deteresa, R.3    Brown, T.4    Davies, P.5    Fuld, P.6
  • 31
    • 39049170344 scopus 로고    scopus 로고
    • Cognitive reserve hypothesis: Pittsburgh Compound B and ?uor-odeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease
    • Kemppainen NM, Aalto S, Karrasch M, Nagren K, Savisto N, Oikonen V, et al. Cognitive reserve hypothesis: Pittsburgh Compound B and ?uor-odeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease. Ann Neurol 2008; 63: 112-8
    • (2008) Ann Neurol , vol.63 , pp. 112-8
    • Kemppainen, N.M.1    Aalto, S.2    Karrasch, M.3    Nagren, K.4    Savisto, N.5    Oikonen, V.6
  • 32
    • 33750975078 scopus 로고    scopus 로고
    • Voxel-based analysis of PET amyloid ligand [11C]PIB uptake in Alzheimer disease
    • Kemppainen NM, Aalto S, Wilson IA, Nagren K, Helin S, Bruck A, et al. Voxel-based analysis of PET amyloid ligand [11C]PIB uptake in Alzheimer disease. Neurology 2006; 67: 1575-80 (Pubitemid 44747926)
    • (2006) Neurology , vol.67 , pp. 1575-80
    • Kemppainen, N.M.1    Aalto, S.2    Wilson, I.A.3    Nagren, K.4    Helin, S.5    Bruck, A.6
  • 33
    • 10744232413 scopus 로고    scopus 로고
    • Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B.
    • Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol 2004; 55: 306-319 (Pubitemid 38269583)
    • (2004) Ann Neurol , vol.55 , pp. 306-19
    • Klunk, W.E.1    Engler, H.2    Nordberg, A.3    Wang, Y.4    Blomqvist, G.5    Holt, D.P.6
  • 35
    • 0345599147 scopus 로고    scopus 로고
    • Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease
    • Kramer JH, Jurik J, Sha SJ, Rankin KP, Rosen HJ, Johnson JK, et al. Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease. Cogn Behav Neurol 2003; 16: 211-218 (Pubitemid 37517826)
    • (2003) Cogn Behav Neurol , vol.16 , pp. 211-18
    • Kramer, J.H.1    Jurik, J.2    Sha, S.J.3    Rankin, K.P.4    Rosen, H.J.5    Johnson, J.K.6
  • 37
    • 0030609886 scopus 로고    scopus 로고
    • Production of [11C]CH3I by single pass reaction of [11C]CH4 with I2
    • Link JM, Krohn KA, Clark JC. Production of [11C]CH3I by single pass reaction of [11C]CH4 with I2. Nucl Med Biol 1997; 24: 93-7
    • (1997) Nucl Med Biol , vol.24 , pp. 93-7
    • Link, J.M.1    Krohn, K.A.2    Clark, J.C.3
  • 38
    • 34848885454 scopus 로고    scopus 로고
    • PIB is a non-speci?c imaging marker of amyloid-beta (Abeta) peptide-related cerebral amyloidosis
    • Lockhart A, Lamb JR, Osredkar T, Sue LI, Joyce JN, Ye L, et al. PIB is a non-speci?c imaging marker of amyloid-beta (Abeta) peptide-related cerebral amyloidosis. Brain 2007; 130: 2607-15 (Pubitemid 47511709)
    • (2007) Brain , vol.130 , pp. 2607-15
    • Lockhart, A.1    Lamb, J.R.2    Osredkar, T.3    Sue, L.I.4    Joyce, J.N.5    Ye, L.6
  • 41
    • 0038792263 scopus 로고    scopus 로고
    • Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothia- zoles as amyloid imaging agents
    • Mathis CA, Wang Y, Holt DP, Huang GF, Debnath ML, Klunk WE. Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothia- zoles as amyloid imaging agents. J Med Chem 2003; 46: 2740-54 (Pubitemid 36702542)
    • (2003) J Med Chem , vol.46 , pp. 2740-54
    • Mathis, C.A.1    Wang, Y.2    Holt, D.P.3    Huang, G.F.4    Debnath, M.L.5    Klunk, W.E.6
  • 42
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34: 939-44 (Pubitemid 14076461)
    • (1984) Neurology , vol.34 , pp. 939-44
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 45
    • 33747048954 scopus 로고    scopus 로고
    • [11C]PIB in a nondemented population:potential antecedent marker of Alzheimer disease
    • Mintun MA, Larossa GN, Sheline YI, Dence CS, Lee SY, Mach RH, et al. [ 11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease. Neurology 2006; 67: 446-52 (Pubitemid 44214969)
    • (2006) Neurology , vol.67 , pp. 446-52
    • Mintun, M.A.1    Larossa, G.N.2    Sheline, Y.I.3    Dence, C.S.4    Lee, S.Y.5    MacH, R.H.6
  • 46
    • 0027425211 scopus 로고
    • The clinical dementia rating (CDR): Current version and scoring rules
    • Morris JC. The clinical dementia rating (CDR): current version and scoring rules. Neurology 1993; 43: 2412-4 (Pubitemid 23346995)
    • (1993) Neurology , vol.43 , pp. 2412-4
    • Morris, J.C.1
  • 47
    • 35648932901 scopus 로고    scopus 로고
    • Beta-amyloid imaging and memory in non-demented individuals: Evidence for preclinical Alzheimer's disease
    • Pike KE, Savage G, Villemagne VL, Ng S, Moss SA, Maruff P, et al. Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease. Brain 2007; 130: 2837-44 (Pubitemid 350033975)
    • (2007) Brain , vol.130 , pp. 2837-44
    • Pike, K.E.1    Savage, G.2    Villemagne, V.L.3    Ng, S.4    Moss, S.A.5    Maruff, P.6
  • 48
    • 27544513056 scopus 로고    scopus 로고
    • Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B
    • Price JC, Klunk WE, Lopresti BJ, Lu X, Hoge JA, Ziolko SK, et al. Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B. J Cereb Blood Flow Metab 2005; 25: 1528-47 (Pubitemid 41541962)
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1528-47
    • Price, J.C.1    Klunk, W.E.2    Lopresti, B.J.3    Lu, X.4    Hoge, J.A.5    Ziolko, S.K.6
  • 49
    • 0032989712 scopus 로고    scopus 로고
    • Tangles and plaques in nondemented aging and 'preclinical' alzheimer's disease
    • DOI 10.1002/1531-8249(199903)45:3<358::AID-ANA12>3.0.CO;2-X
    • Price JL, Morris JC. Tangles and plaques in nondemented aging and 'preclinical' Alzheimer's disease. Ann Neurol 1999; 45: 358-68 (Pubitemid 29120041)
    • (1999) Annals of Neurology , vol.45 , Issue.3 , pp. 358-368
    • Price, J.L.1    Morris, J.C.2
  • 50
    • 30344466664 scopus 로고    scopus 로고
    • Functional connectivity with the hippocampus during successful memory formation
    • DOI 10.1002/hipo.20141
    • Ranganath C, Heller A, Cohen MX, Brozinsky CJ, Rissman J. Functional connectivity with the hippocampus during successful memory formation. Hippocampus 2005; 15: 997-1005. (Pubitemid 43056989)
    • (2005) Hippocampus , vol.15 , Issue.8 , pp. 997-1005
    • Ranganath, C.1    Heller, A.2    Cohen, M.X.3    Brozinsky, C.J.4    Rissman, J.5
  • 51
    • 33747888336 scopus 로고    scopus 로고
    • Differential aging of the brain: Patterns, cognitive correlates and modifers
    • Raz N, Rodrigue KM. Differential aging of the brain: patterns, cognitive correlates and modi?ers. Neurosci Biobehav Rev 2006; 30: 730-48 (Pubitemid 44292292)
    • (2006) Neurosci Biobehav Rev , vol.30 , pp. 730-48
    • Raz, N.1    Rodrigue, K.M.2
  • 52
    • 0000119553 scopus 로고
    • Validity of the trailmaking test as an indication of organic brain damage
    • Reitan RM. Validity of the trailmaking test as an indication of organic brain damage. Percept Mot Skills 1958; 8: 271-6
    • (1958) Percept Mot Skills , vol.8 , pp. 271-6
    • Reitan, R.M.1
  • 54
    • 0026132055 scopus 로고
    • Effects of adult age on structural and operational capacities in working memory
    • Salthouse TA, Babcock RL, Shaw RJ. Effects of adult age on structural and operational capacities in working memory. Psychol Aging 1991; 6: 118-27.
    • (1991) Psychol Aging , vol.6 , pp. 118-27
    • Salthouse, T.A.1    Babcock, R.L.2    Shaw, R.J.3
  • 58
    • 0034086973 scopus 로고    scopus 로고
    • The course of cognitive impairment in preclinical Alzheimer disease: Three- and 6-year follow-up of a population-based sample
    • Small BJ, Fratiglioni L, Viitanen M, Winblad B, Backman L. The course of cognitive impairment in preclinical Alzheimer disease: three- and 6-year follow-up of a population-based sample. Arch Neurol 2000; 57: 839-44 (Pubitemid 30397186)
    • (2000) Arch Neurol , vol.57 , pp. 839-44
    • Small, B.J.1    Fratiglioni, L.2    Viitanen, M.3    Winblad, B.4    Backman, L.5
  • 59
    • 0033594355 scopus 로고    scopus 로고
    • Selective decline in memory function among healthy elderly
    • Small SA, Stern Y, Tang M, Mayeux R. Selective decline in memory function among healthy elderly. Neurology 1999; 52: 1392-6 (Pubitemid 29190529)
    • (1999) Neurology , vol.52 , pp. 1392-6
    • Small, S.A.1    Stern, Y.2    Tang, M.3    Mayeux, R.4
  • 61
    • 33747591635 scopus 로고    scopus 로고
    • Cognitive reserve and Alzheimer disease
    • DOI 10.1097/00002093-200607001-00010, PII 0000209320060700100010
    • Stern Y. Cognitive reserve and Alzheimer disease. Alzheimer Dis Assoc Disord 2006; 20: S69-S74. (Pubitemid 44265854)
    • (2006) Alzheimer Disease and Associated Disorders , vol.20 , Issue.SUPPL. 2
    • Stern, Y.1
  • 62
    • 0014326852 scopus 로고
    • Observations on the brains of non-demented old people
    • Tomlinson BE, Blessed G, Roth M. Observations on the brains of non-demented old people. J Neurol Sci 1968; 7: 331-56
    • (1968) J Neurol Sci , vol.7 , pp. 331-56
    • Tomlinson, B.E.1    Blessed, G.2    Roth, M.3
  • 63
    • 43849084404 scopus 로고    scopus 로고
    • Abeta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease
    • Villemagne VL, Pike KE, Darby D, Maruff P, Savage G, Ng S, et al. Abeta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease. Neuropsycho- logia 2008; 46: 1688-97
    • (2008) Neuropsycho-logia , vol.46 , pp. 1688-1697
    • Villemagne, V.L.1    Pike, K.E.2    Darby, D.3    Maruff, P.4    Savage, G.5    Ng, S.6
  • 64
    • 34248190279 scopus 로고    scopus 로고
    • A beta oligomers-a decade of discovery
    • Walsh DM, Selkoe DJ. A beta oligomers-a decade of discovery. J Neurochem 2007; 101: 1172-84
    • (2007) J Neurochem , vol.101 , pp. 1172-84
    • Walsh, D.M.1    Selkoe, D.J.2
  • 65
    • 33646850082 scopus 로고    scopus 로고
    • Changes in hippocampal connectivity in the early stages of Alzheimer's disease: Evidence from resting state fMRI
    • DOI 10.1016/j.neuroimage.2005.12.033, PII S1053811905025711
    • Wang L, Zang Y, He Y, Liang M, Zhang X, Tian L, et al. Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI. Neuroimage 2006; 31: 496-504. (Pubitemid 43776683)
    • (2006) NeuroImage , vol.31 , Issue.2 , pp. 496-504
    • Wang, L.1    Zang, Y.2    He, Y.3    Liang, M.4    Zhang, X.5    Tian, L.6    Wu, T.7    Jiang, T.8    Li, K.9
  • 69
    • 33748329435 scopus 로고    scopus 로고
    • Comparative assessment of statistical brain MR image segmentation algorithms and their impact on partial volume correction in PET
    • Zaidi H, Ruest T, Schoenahl F, Montandon ML. Comparative assessment of statistical brain MR image segmentation algorithms and their impact on partial volume correction in PET. Neuroimage 2006; 32: 1591-607 (Pubitemid 44332287)
    • (2006) Neuroimage , vol.32 , pp. 1591-607
    • Zaidi, H.1    Ruest, T.2    Schoenahl, F.3    Montandon, M.L.4
  • 70
    • 66549117064 scopus 로고
    • The stroop color-word test: A paradigm for procedural learning
    • Zec RF. The stroop color-word test: A paradigm for procedural learning. Arch Clin Neuropsychol 1986; 1: 274-5
    • (1986) Arch Clin Neuropsychol , vol.1 , pp. 274-5
    • Zec, R.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.