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Volumn 10, Issue 4, 2006, Pages 371-378

No evidence for allelic association of serotonin 2A receptor and transporter gene polymorphisms with depression in Alzheimer disease

Author keywords

5 HTTLPR; Depression; Polymorphisms; Serotoninergic system; T102C

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E4; SEROTONIN; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER;

EID: 33846954369     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2006-10405     Document Type: Article
Times cited : (36)

References (51)
  • 1
    • 0002545737 scopus 로고
    • The psychopathology of dementia
    • J. Morris, ed, Marcel Dekker, New York
    • P.N. Tariot and L. Blazina, The psychopathology of dementia, in: Handbook of dementing illnesses, J. Morris, ed., Marcel Dekker, New York, 1994, pp. 461-475.
    • (1994) Handbook of dementing illnesses , pp. 461-475
    • Tariot, P.N.1    Blazina, L.2
  • 2
    • 0036519176 scopus 로고    scopus 로고
    • Provisional diagnostic criteria for depression of Alzheimer disease: Rationale and background
    • J.T. Olin, I.R. Katz, B.S. Meyers, L.S. Schneider and B.D. Lebowitz, Provisional diagnostic criteria for depression of Alzheimer disease: rationale and background, Am J Geriatr Psychiatry 10 (2002), 129-141.
    • (2002) Am J Geriatr Psychiatry , vol.10 , pp. 129-141
    • Olin, J.T.1    Katz, I.R.2    Meyers, B.S.3    Schneider, L.S.4    Lebowitz, B.D.5
  • 6
    • 0029015240 scopus 로고
    • Altered serotonin transporter sites in Alzheimer's disease raphe and hippocampus
    • S.M. Tejani-Butt, J. Yang and A.C. Pawlyk, Altered serotonin transporter sites in Alzheimer's disease raphe and hippocampus, Neuroreport 6 (1995), 1207-1210.
    • (1995) Neuroreport , vol.6 , pp. 1207-1210
    • Tejani-Butt, S.M.1    Yang, J.2    Pawlyk, A.C.3
  • 7
    • 0035121739 scopus 로고    scopus 로고
    • Role of serotonin in the behavioral and psychological symptoms of dementia
    • K.L. Lanctot, N. Herrmann and P. Mazzotta, Role of serotonin in the behavioral and psychological symptoms of dementia, J Neuropsychiatry Clin Neurosci 13 (2001), 5-21.
    • (2001) J Neuropsychiatry Clin Neurosci , vol.13 , pp. 5-21
    • Lanctot, K.L.1    Herrmann, N.2    Mazzotta, P.3
  • 10
    • 14444278967 scopus 로고    scopus 로고
    • T. Li, C. Holmes, P.C. Sham, H. Vallada, J. Birkett, G. Kirov, K.P. Lesch, J. Powell, S. Lovestone and D. Collier, Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimer's disease, Neuroreport 8 (1997), 683-686.
    • T. Li, C. Holmes, P.C. Sham, H. Vallada, J. Birkett, G. Kirov, K.P. Lesch, J. Powell, S. Lovestone and D. Collier, Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimer's disease, Neuroreport 8 (1997), 683-686.
  • 11
    • 0031663853 scopus 로고    scopus 로고
    • J.R. Oliveira, R.M. Gallindo, L.G. Maia, P.R. Brito-Marques, P.A. Otto, M.R. Passos-Bueno, M.A. Morais, Jr. and M. Zatz, The short variant of the polymorphism within the promoter region of the serotonin transporter gene is a risk factor for late onset Alzheimer's disease, Mol Psychiatry 3 (1998), 438-441.
    • J.R. Oliveira, R.M. Gallindo, L.G. Maia, P.R. Brito-Marques, P.A. Otto, M.R. Passos-Bueno, M.A. Morais, Jr. and M. Zatz, The short variant of the polymorphism within the promoter region of the serotonin transporter gene is a risk factor for late onset Alzheimer's disease, Mol Psychiatry 3 (1998), 438-441.
  • 14
    • 17844377615 scopus 로고    scopus 로고
    • HTR2A: Association and expression studies in neuropsychiatric genetics
    • N. Norton and M.J. Owen, HTR2A: association and expression studies in neuropsychiatric genetics, Ann Med 37 (2005), 121-129.
    • (2005) Ann Med , vol.37 , pp. 121-129
    • Norton, N.1    Owen, M.J.2
  • 15
    • 0020656803 scopus 로고
    • Decreased imipramine binding in the brains of patients with depressive illness
    • E.K. Perry, E.F. Marshall, G. Blessed, B.E. Tomlinson and R.H. Perry, Decreased imipramine binding in the brains of patients with depressive illness, Br J Psychiatry 142 (1983), 188-192.
    • (1983) Br J Psychiatry , vol.142 , pp. 188-192
    • Perry, E.K.1    Marshall, E.F.2    Blessed, G.3    Tomlinson, B.E.4    Perry, R.H.5
  • 16
    • 0038045485 scopus 로고    scopus 로고
    • Involvement of serotonin in depression: Evidence from postmortem and imaging studies of serotonin receptors and the serotonin transporter
    • C.A. Stockmeier, Involvement of serotonin in depression: evidence from postmortem and imaging studies of serotonin receptors and the serotonin transporter, J Psychiatr Res 37 (2003), 357-373.
    • (2003) J Psychiatr Res , vol.37 , pp. 357-373
    • Stockmeier, C.A.1
  • 17
    • 0029874311 scopus 로고    scopus 로고
    • Presynaptic serotonergic markers in community-acquired cases of Alzheimer's disease: Correlations with depression and neuroleptic medication
    • C.P. Chen, J.T. Alder, D.M. Bowen, M.M. Esiri, B. McDonald, T. Hope, K.A. Jobst and P.T. Francis, Presynaptic serotonergic markers in community-acquired cases of Alzheimer's disease: correlations with depression and neuroleptic medication, J Neurochem 66 (1996), 1592-1598.
    • (1996) J Neurochem , vol.66 , pp. 1592-1598
    • Chen, C.P.1    Alder, J.T.2    Bowen, D.M.3    Esiri, M.M.4    McDonald, B.5    Hope, T.6    Jobst, K.A.7    Francis, P.T.8
  • 18
    • 33646084617 scopus 로고    scopus 로고
    • A study of the serotonin transporter in the prefrontal cortex in late-life depression and Alzheimer's disease with and without depression
    • A.J. Thomas, M. Hendriksen, M. Piggott, I.N. Ferrier, E. Perry, P. Ince and J.T. O'brien, A study of the serotonin transporter in the prefrontal cortex in late-life depression and Alzheimer's disease with and without depression, Neuropathol Appl Neurobiol 32 (2006), 296-303.
    • (2006) Neuropathol Appl Neurobiol , vol.32 , pp. 296-303
    • Thomas, A.J.1    Hendriksen, M.2    Piggott, M.3    Ferrier, I.N.4    Perry, E.5    Ince, P.6    O'brien, J.T.7
  • 19
    • 0033862484 scopus 로고    scopus 로고
    • Immunocytochemical study of the dorsal and median raphe nuclei in patients with Alzheimer's disease prospectively assessed for behavioural changes
    • C.P. Chen, S.L. Eastwood, T. Hope, B. McDonald, P.T. Francis and M.M. Esiri, Immunocytochemical study of the dorsal and median raphe nuclei in patients with Alzheimer's disease prospectively assessed for behavioural changes, Neuropathol Appl Neurobiol 26 (2000), 347-355.
    • (2000) Neuropathol Appl Neurobiol , vol.26 , pp. 347-355
    • Chen, C.P.1    Eastwood, S.L.2    Hope, T.3    McDonald, B.4    Francis, P.T.5    Esiri, M.M.6
  • 20
    • 2942565912 scopus 로고    scopus 로고
    • Neuropathological study of the dorsal raphe nuclei in late-life depression and Alzheimer's disease with and without depression
    • M. Hendricksen, A.J. Thomas, I.N. Ferrier, P. Ince and J.T. O'Brien, Neuropathological study of the dorsal raphe nuclei in late-life depression and Alzheimer's disease with and without depression, Am J Psychiatry 161 (2004), 1096-1102.
    • (2004) Am J Psychiatry , vol.161 , pp. 1096-1102
    • Hendricksen, M.1    Thomas, A.J.2    Ferrier, I.N.3    Ince, P.4    O'Brien, J.T.5
  • 21
    • 0032697987 scopus 로고    scopus 로고
    • C.C. Meltzer, J.C. Price, C.A. Mathis, P.J. Greer, M.N. Cantwell, P.R. Houck, B.H. Mulsant, D. Ben-Eliezer, B. Lopresti, S.T. DeKosky and C.F. Reynolds, 3rd., PET imaging of serotonin type 2A receptors in late-life neuropsychiatric disorders, Am J Psychiatry 15 (1999), 1871-1878.
    • C.C. Meltzer, J.C. Price, C.A. Mathis, P.J. Greer, M.N. Cantwell, P.R. Houck, B.H. Mulsant, D. Ben-Eliezer, B. Lopresti, S.T. DeKosky and C.F. Reynolds, 3rd., PET imaging of serotonin type 2A receptors in late-life neuropsychiatric disorders, Am J Psychiatry 15 (1999), 1871-1878.
  • 22
    • 1042289665 scopus 로고    scopus 로고
    • Serotoninergic polymorphisms (5-HTTLPR and 5-HT2A): Association studies with psychosis in Alzheimer disease
    • A. Rocchi, D. Micheli, R. Ceravolo, M.L. Manca, G. Tognoni, G. Siciliano and L. Murri, Serotoninergic polymorphisms (5-HTTLPR and 5-HT2A): association studies with psychosis in Alzheimer disease, Genet Test 7 (2003), 309-314.
    • (2003) Genet Test , vol.7 , pp. 309-314
    • Rocchi, A.1    Micheli, D.2    Ceravolo, R.3    Manca, M.L.4    Tognoni, G.5    Siciliano, G.6    Murri, L.7
  • 23
    • 84871115139 scopus 로고
    • American Psychiatric Association, 4th ed, American Psychiatric Association, Washington, DC
    • American Psychiatric Association, Diagnostic and Statistic Manual of Mental Disorders, (4th ed.), American Psychiatric Association, Washington, DC. 1994.
    • (1994) Diagnostic and Statistic Manual of Mental Disorders
  • 24
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • G. McKhann, D. Drachman, M. Folstein, R. Katzman, D. Price and E.M. Stadlan, Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease, Neurology 34 (1984), 939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 26
    • 0031438475 scopus 로고    scopus 로고
    • Clinical dementia rating: A reliable and valid diagnostic and staging measure for dementia of the Alzheimer type
    • discussion 177-178
    • J.C. Morris, Clinical dementia rating: a reliable and valid diagnostic and staging measure for dementia of the Alzheimer type, Int Psychogeriatr 9(Suppl 1) (1997), 173-176, discussion 177-178.
    • (1997) Int Psychogeriatr , vol.9 , Issue.SUPPL. 1 , pp. 173-176
    • Morris, J.C.1
  • 27
    • 23844474755 scopus 로고    scopus 로고
    • Alzheimer's Disease Cooperative Study, Detailed assessment of activities of daily living in moderate to severe Alzheimer's disease
    • D. Galasko, F. Schmitt, R. Thomas, S. Jin and D. Bennett, Alzheimer's Disease Cooperative Study, Detailed assessment of activities of daily living in moderate to severe Alzheimer's disease, J Int Neuropsychol Soc 11 (2005), 446-453.
    • (2005) J Int Neuropsychol Soc , vol.11 , pp. 446-453
    • Galasko, D.1    Schmitt, F.2    Thomas, R.3    Jin, S.4    Bennett, D.5
  • 28
    • 0027985334 scopus 로고    scopus 로고
    • J.L. Cummings, M. Mega and K. Gray, S. Rosenberg-Thompson, D.A. Carusi, J. Gornbein, The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia, Neurology 44 (1994), 2308-2314.
    • J.L. Cummings, M. Mega and K. Gray, S. Rosenberg-Thompson, D.A. Carusi, J. Gornbein, The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia, Neurology 44 (1994), 2308-2314.
  • 29
    • 0027300190 scopus 로고
    • An MspI polymorphism in the human serotonin receptor gene (HTR2): Detection by DGGE and RFLP analysis
    • J.T. Warren, Jr., M.L. Peacock, L.C. Rodriguez and J.K. Fink, An MspI polymorphism in the human serotonin receptor gene (HTR2): detection by DGGE and RFLP analysis, Hum Mol Genet 2 (1993), 338.
    • (1993) Hum Mol Genet , vol.2 , pp. 338
    • Warren Jr., J.T.1    Peacock, M.L.2    Rodriguez, L.C.3    Fink, J.K.4
  • 30
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI
    • J.E. Hixson and D.T. Vernier, Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI, J Lipid Res 31 (1990), 545-548.
    • (1990) J Lipid Res , vol.31 , pp. 545-548
    • Hixson, J.E.1    Vernier, D.T.2
  • 31
    • 85039204214 scopus 로고    scopus 로고
    • S. Schneider, D. Roessli and L. Excofier, Arlequin: A Software for Population Genetics Data analysis, Ver 2.000. Genetics and Biometry Lab, Dept. of Anthropology, University of Geneva, Switzerland 2000
    • S. Schneider, D. Roessli and L. Excofier, Arlequin: A Software for Population Genetics Data analysis, Ver 2.000. Genetics and Biometry Lab, Dept. of Anthropology, University of Geneva, Switzerland (2000).
  • 32
    • 0034016372 scopus 로고    scopus 로고
    • Mental and behavioral disturbances in dementia: Findings from the Cache County Study on Memory in Aging
    • C.G. Lyketsos, M. Steinberg, J.T. Tschanz, M.C. Norton, D.C. Steffens and J. Breitner, Mental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in Aging, Am J Psychiatry 157 (2000), 708-714.
    • (2000) Am J Psychiatry , vol.157 , pp. 708-714
    • Lyketsos, C.G.1    Steinberg, M.2    Tschanz, J.T.3    Norton, M.C.4    Steffens, D.C.5    Breitner, J.6
  • 33
    • 0034640695 scopus 로고    scopus 로고
    • Alzheimer's disease and 5-HTTLPR polymorphism of the serotonin transporter gene: No evidence for an association
    • H. Kunugi, A. Ueki, M. Otsuka, K. Isse, H. Hirasawa, N. Kato, T. Nabika, S. Kobayashi and S. Nanko, Alzheimer's disease and 5-HTTLPR polymorphism of the serotonin transporter gene: no evidence for an association, Am J Med Genet 96 (2000), 307-309.
    • (2000) Am J Med Genet , vol.96 , pp. 307-309
    • Kunugi, H.1    Ueki, A.2    Otsuka, M.3    Isse, K.4    Hirasawa, H.5    Kato, N.6    Nabika, T.7    Kobayashi, S.8    Nanko, S.9
  • 35
    • 0034940183 scopus 로고    scopus 로고
    • S.J. Tsai, C.J. Hong, T.Y. Liu, C.Y. Cheng and H.C. Liu, Association study for a functional serotonin transporter gene polymorphism and late-onset Alzheimer's disease for Chinese patients, Neuropsychobiology 44 (2001), 27-30.
    • S.J. Tsai, C.J. Hong, T.Y. Liu, C.Y. Cheng and H.C. Liu, Association study for a functional serotonin transporter gene polymorphism and late-onset Alzheimer's disease for Chinese patients, Neuropsychobiology 44 (2001), 27-30.
  • 37
    • 0344418678 scopus 로고    scopus 로고
    • Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide
    • G. Turecki, R. Briere, K. Dewar, T. Antonetti, A.D. Lesage, M. Seguin, N. Chawky, C. Vanier, M. Alda, R. Joober, C. Benkelfat and G.A. Rouleau, Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide, Am J Psychiatry 156 (1999), 1456-1458.
    • (1999) Am J Psychiatry , vol.156 , pp. 1456-1458
    • Turecki, G.1    Briere, R.2    Dewar, K.3    Antonetti, T.4    Lesage, A.D.5    Seguin, M.6    Chawky, N.7    Vanier, C.8    Alda, M.9    Joober, R.10    Benkelfat, C.11    Rouleau, G.A.12
  • 38
    • 0037086178 scopus 로고    scopus 로고
    • Differential expression of the "C" and "T" alleles of the 5-HT2A receptor gene in the temporal cortex of normal individuals and schizophrenics
    • O.O. Polesskaya and B.P. Sokolov, Differential expression of the "C" and "T" alleles of the 5-HT2A receptor gene in the temporal cortex of normal individuals and schizophrenics, J Neurosci Res 67 (2002), 812-822.
    • (2002) J Neurosci Res , vol.67 , pp. 812-822
    • Polesskaya, O.O.1    Sokolov, B.P.2
  • 39
    • 0031596301 scopus 로고    scopus 로고
    • Alzheimer's disease
    • 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset
    • C. Holmes, M.J. Arranz, J.F. Powell, D.A. Collier and S. Lovestone, 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease, Hum Mol Genet 7 (1998), 1507-1509.
    • (1998) Hum Mol Genet , vol.7 , pp. 1507-1509
    • Holmes, C.1    Arranz, M.J.2    Powell, J.F.3    Collier, D.A.4    Lovestone, S.5
  • 40
    • 0042821615 scopus 로고    scopus 로고
    • Depression in Alzheimer's disease: The effect of serotonin receptor gene variation
    • C. Holmes, M. Arranz, D. Collier, J. Powell and S. Lovestone, Depression in Alzheimer's disease: the effect of serotonin receptor gene variation, Am J Med Genet 119 (2003), 40-43.
    • (2003) Am J Med Genet , vol.119 , pp. 40-43
    • Holmes, C.1    Arranz, M.2    Collier, D.3    Powell, J.4    Lovestone, S.5
  • 43
    • 4043174258 scopus 로고    scopus 로고
    • Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease
    • F. Assal, M. Alarcon, E.C. Solomon, D. Masterman, D.H. Geschwind and J.L. Cummings, Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease, Arch Neurol 61 (2004), 1249-1253.
    • (2004) Arch Neurol , vol.61 , pp. 1249-1253
    • Assal, F.1    Alarcon, M.2    Solomon, E.C.3    Masterman, D.4    Geschwind, D.H.5    Cummings, J.L.6
  • 44
    • 3042855136 scopus 로고    scopus 로고
    • 5-HT2A T102C receptor polymorphism and neuropsychiatric symptoms in Alzheimer's disease
    • L.C. Lam, N.L. Tang, S.L. Ma, W. Zhang and H.F. Chiu, 5-HT2A T102C receptor polymorphism and neuropsychiatric symptoms in Alzheimer's disease, Int J Geriatr Psychiatry 19 (2004), 523-526.
    • (2004) Int J Geriatr Psychiatry , vol.19 , pp. 523-526
    • Lam, L.C.1    Tang, N.L.2    Ma, S.L.3    Zhang, W.4    Chiu, H.F.5
  • 51
    • 0027051464 scopus 로고
    • Clinical and neuropathological correlates of depression in Alzheimer's disease
    • H. Forstl, A. Burns, P. Luthert, N. Cairns, P. Lantos and R. Levy, Clinical and neuropathological correlates of depression in Alzheimer's disease, Psychol Med 22 (1992), 877-884.
    • (1992) Psychol Med , vol.22 , pp. 877-884
    • Forstl, H.1    Burns, A.2    Luthert, P.3    Cairns, N.4    Lantos, P.5    Levy, R.6


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