Methods for investigation of targeted kinase inhibitor therapy using chemical proteomics and phosphorylation profiling

Biochemical Pharmacology

Volumn 80, Issue 5, 2010, Pages 739-747

  Fang, Bin ^a   Haura, Eric B ^a   Smalley, Keiran S ^a   Eschrich, Steven A ^a   Koomen, John M ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

Drug resistance; Drug response; Mass spectrometry; Phosphoproteomics; Phosphorylation; Targeted therapy

Indexed keywords

PHOSPHOSERINE; PHOSPHOTHREONINE; PHOSPHOTRANSFERASE INHIBITOR; PHOSPHOTYROSINE;

AFFINITY CHROMATOGRAPHY; APOPTOSIS; CELL DIVISION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEOMICS; REVIEW;

ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, AFFINITY; HUMANS; MASS SPECTROMETRY; NEOPLASMS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEOMICS;

EID: 77954216493     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.03.027     Document Type: Review

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