An efficient proteomics method to identify the cellular targets of protein kinase inhibitors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 26, 2003, Pages 15434-15439

  Godl, Klaus ^a   Wissing, Josef ^a   Kurtenbach, Alexander ^a   Habenberger, Peter ^a   Blencke, Stephanie ^a   Gutbrod, Heidrun ^a   Salassidis, Kostadinos ^a   Stein Gerlach, Matthias ^a   Missio, Andrea ^a   Cotten, Matt ^a   Daub, Henrik ^a  

^a Axxima Pharmaceuticals AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYCLIN DEPENDENT KINASE; ENZYME; PROTEIN KINASE INHIBITOR; RIP LIKE INTERACTING CASPASE LIKE APOPTOSIS REGULATORY PROTEIN; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; CELL CULTURE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TARGETING; DRUG TRANSPORT; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEOMICS; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME INHIBITORS; HELA CELLS; HUMANS; MASS SPECTROMETRY; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PROTEOMICS; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA;

EID: 9144219693     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2535024100     Document Type: Article

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