Sequence and structure continuity of evolutionary importance improves protein functional site discovery and annotation

Protein Science

Volumn 19, Issue 7, 2010, Pages 1296-1311

  Wilkins, A D ^a,b   Lua, R ^a   Erdin, S ^a,b   Ward, R M ^a,b   Lichtarge, O ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b W M Keck Center for Interdisciplinary Bioscience Training   (United States)

Author keywords

Binding site prediction; Evolutionary trace; Functional annotation; Sequence selection

Indexed keywords

ALGORITHM; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CORRELATION ANALYSIS; HUMAN; MOLECULAR EVOLUTION; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SENSITIVITY AND SPECIFICITY; STRUCTURAL PROTEOMICS; STRUCTURE ACTIVITY RELATION; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

PROTEIN;

ALGORITHMS; AMINO ACID SEQUENCE; COMPUTATIONAL BIOLOGY; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEINS;

EID: 77953963521     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.406     Document Type: Article

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