Rate4Site: An algorithmic tool for the identification of functional regions in proteins by surface mapping of evolutionary determinants within their homologues

Bioinformatics

Volumn 18, Issue SUPPL. 1, 2002, Pages

  Pupko, Tal ^a   Bell, Rachel E ^b   Mayrose, Itay ^b   Glaser, Fabian ^b   Ben Tal, Nir ^b  

^a INSTITUTE OF STATISTICAL MATHEMATICS   (Japan)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Evolutionary conservation; Maximum likelihood; Protein evolution; Rate variation among sites; SH2 domains

Indexed keywords

AMINO ACID; PROTEIN;

ALGORITHM; CONFERENCE PAPER; GENETIC CONSERVATION; MAXIMUM LIKELIHOOD METHOD; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SRC HOMOLOGY DOMAIN; THREE DIMENSIONAL IMAGING; AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; CLUSTER ANALYSIS; COMPARATIVE STUDY; COMPUTER PROGRAM; EVALUATION; GENE EXPRESSION PROFILING; GENETICS; METHODOLOGY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; VALIDATION STUDY;

ALGORITHMS; AMINO ACID SEQUENCE; AMINO ACIDS; CLUSTER ANALYSIS; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; GENE EXPRESSION PROFILING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SEQUENCE HOMOLOGY, AMINO ACID; SOFTWARE; SRC HOMOLOGY DOMAINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0002218484     PISSN: 13674803     EISSN: 13674811     Source Type: Journal    
DOI: 10.1093/bioinformatics/18.suppl_1.S71     Document Type: Conference Paper

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