Intracellular location and cell context-dependent function of protein kinase D

Immunity

Volumn 19, Issue 4, 2003, Pages 491-501

  Marklund, Ulrica ^a   Lightfoot, Kurt ^a   Cantrell, Doreen ^b  

^a THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD5 ANTIGEN; CD8 ANTIGEN; PROTEIN KINASE D; PROTEIN SERINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE; CELL POPULATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; T LYMPHOCYTE; THYMOCYTE; TRANSGENICS; UPREGULATION; WILD TYPE;

EID: 0142250491     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(03)00260-7     Document Type: Article

References (55)

1. Aifantis I., Pivniouk V.I., Gartner F., Feinberg J., Swat W., Alt F.W., von Boehmer H., Geha R.S. Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein. J. Exp. Med. 190:1999;1093-1102.
2. Azzam H.S., Grinberg A., Lui K., Shen H., Shores E.W., Love P.E. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity. J. Exp. Med. 188:1998;2301-2311.
3. Baron C.L., Malhotra V. Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. Science. 295:2002;325-328.
4. Cantrell D.A. T-cell antigen receptor signal transduction. Immunology. 105:2002;369-374.
5. Corre I., Gomez M., Vielkind S., Cantrell D.A. Analysis of thymocyte development reveals that the GTPase RhoA is a positive regulator of T cell receptor responses in vivo. J. Exp. Med. 194:2001;903-914.
6. Gartner F., Alt F.W., Monroe R., Chu M., Sleckman B.P., Davidson L., Swat W. Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion. Immunity. 10:1999;537-546.
7. Godfrey D.I., Kennedy J., Suda T., Zlotnik A. A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 150:1993;4244-4252.
8. Godfrey D.I., Kennedy J., Mombaerts P., Tonegawa S., Zlotnik A. Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. J. Immunol. 152:1994;4783-4792.
9. Gomez M., Tybulewicz V., Cantrell D.A. Control of pre-T cell proliferation and differentiation by the GTPase Rac-I. Nat. Immunol. 1:2000;348-352.
10. Hausser A., Link G., Bamberg L., Burzlaff A., Lutz S., Pfizenmaier K., Johannes F.J. Structural requirements for localization and activation of protein kinase C mu (PKC mu) at the Golgi compartment. J. Cell Biol. 156:2002;65-74.
11. Hoffman E.S., Passoni L., Crompton T., Leu T.M., Schatz D.G., Koff A., Owen M.J., Hayday A.C. Productive T-cell receptor beta-chain gene rearrangement. coincident regulation of cell cycle and clonality during development in vivo Genes Dev. 10:1996;948-962.
12. Hurd C., Rozengurt E. Uncoupling of protein kinase D from suppression of EGF-dependent c-Jun phosphorylation in cancer cells. Biochem. Biophys. Res. Commun. 302:2003;800-804.
13. Iglesias T., Waldron R.T., Rozengurt E. Identification of in vivo phosphorylation sites required for protein kinase D activation. J. Biol. Chem. 273:1998;27662-27667.
14. Iritani B.M., Alberola-Ila J., Forbush K.A., Perimutter R.M. Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors. Immunity. 10:1999;713-722.
15. Jacobs H., Vandeputte D., Tolkamp L., de Vries E., Borst J., Berns A. CD3 components at the surface of pro-T cells can mediate pre-T cell development in vivo. Eur. J. Immunol. 24:1994;934-939.
16. Jamora C., Yamanouye N., Van Lint J., Laudenslager J., Vandenheede J.R., Faulkner D.J., Malhotra V. Gβγ-mediated regulation of Golgi organization is through the direct activation of protein kinase D. Cell. 98:1999;59-68.
17. Khor B., Sleckman B.P. Allelic exclusion at the TCRbeta locus. Curr. Opin. Immunol. 14:2002;230-234.
18. Kisielow P., Bluthmann H., Staerz U.D., Steinmetz M., von Boehmer H. Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes. Nature. 333:1988;742-746.
19. Koretzky G.A., Myung P.S. Positive and negative regulation of T-cell activation by adaptor proteins. Nat. Rev. Immunol. 1:2001;95-107.
20. Kruisbeek A.M., Haks M.C., Carleton M., Michie A.M., Zuniga-Pflucker J.C., Wiest D.L. Branching out to gain control. how the pre-TCR is linked to multiple functions Immunol. Today. 21:2000;637-644.
21. Liljedahl M., Maeda Y., Colanzi A., Ayala I., Van Lint J., Malhotra V. Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network. Cell. 104:2001;409-420.
22. Matthews S., Iglesias T., Cantrell D., Rozengurt E. Dynamic re-distribution of protein kinase D (PKD) as revealed by a GFP-PKD fusion protein. dissociation from PKD activation FEBS Lett. 457:1999;515-521. a.
23. Matthews S.A., Rozengurt E., Cantrell D. Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/protein kinase Cmu. J. Biol. Chem. 274:1999;26543-26549. b.
24. Matthews S.A., Iglesias T., Rozengurt E., Cantrell D. Spatial and temporal regulation of protein kinase D (PKD). EMBO J. 19:2000;2935-2945. a.
25. Matthews S.A., Rozengurt E., Cantrell D. Protein kinase D. A selective target for antigen receptors and a downstream target for protein kinase C in lymphocytes. J. Exp. Med. 191:2000;2075-2082. b.
26. Matthews S.A., Dayalu R., Thompson L.J., Scharenberg A.M. Regulation of protein kinase Cnu by the B-cell antigen receptor. J. Biol. Chem. 278:2003;9086-9091.
27. Michie A.M., Zuniga-Pflucker J.C. Regulation of thymocyte differentiation. pre-TCR signals and beta-selection Semin. Immunol. 14:2002;311-323.
28. Michie A.M., Soh J.W., Hawley R.G., Weinstein I.B., Zuniga-Pflucker J.C. Allelic exclusion and differentiation by protein kinase C-mediated signals in immature thymocytes. Proc. Natl. Acad. Sci. USA. 98:2001;609-614.
29. Mombaerts P., Iacomini J., Johnson R.S., Herrup K., Tonegawa S., Papaioannou V.E. RAG-1-deficient mice have no mature B and T lymphocytes. Cell. 68:1992;869-877.
30. Na S., Li B., Grewal I.S., Enslen H., Davis R.J., Hanke J.H., Flavell R.A. Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways. Oncogene. 18:1999;7966-7974.
31. Norment A.M., Bogatzki L.Y., Klinger M., Ojala E.W., Bevan M.J., Kay R.J. Transgenic expression of RasGRP1 induces the maturation of double-negative thymocytes and enhances the production of CD8 single-positive thymocytes. J. Immunol. 170:2003;1141-1149.
32. Perlmutter R.M. Control of T cell development by non-receptor protein tyrosine kinases. Cancer Surv. 22:1995;85-95.
33. Pircher H., Burki K., Lang R., Hengartner H., Zinkernagel R.M. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature. 342:1989;559-561.
34. Reif K., Nobes C.D., Thomas G., Hall A., Cantrell D.A. Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways. Curr. Biol. 6:1996;1445-1455.
35. Rey O., Rozengurt E. Protein kinase D interacts with Golgi via its cysteine-rich domain. Biochem. Biophys. Res. Commun. 287:2001;21-26.
36. Rey O., Sinnett-Smith J., Zhukova E., Rozengurt E. Regulated nucleocytoplasmic transport of protein kinase D in response to G protein-coupled receptor activation. J. Biol. Chem. 276:2001;49228-49235. a.
37. Rey O., Young S.H., Cantrell D., Rozengurt E. Rapid protein kinase D translocation in response to G protein-coupled receptor activation. Dependence on protein kinase C. J. Biol. Chem. 276:2001;32616-32626. b.
38. Rey O., Yuan J., Rozengurt E. Intracellular redistribution of protein kinase D2 in response to G-protein-coupled receptor agonists. Biochem. Biophys. Res. Commun. 302:2003;817-824. a.
39. Rey O., Yuan J., Young S.H., Rozengurt E. Protein kinase Cnu/PKD3 nuclear localization, catalytic activation and intracellular redistribution in response to G protein-coupled receptor agonists. J. Biol. Chem. 278:2003;23773-23785. b.
40. Rodewald H.R., Awad K., Moingeon P., D'Adamio L., Rabinowitz D., Shinkai Y., Alt F.W., Reinherz E.L. Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes. in vivo developmental kinetics and T cell receptor beta chain rearrangement status J. Exp. Med. 177:1993;1079-1092.
41. Samelson L.E. Signal transduction mediated by the T cell antigen receptor. the role of adapter proteins Annu. Rev. Immunol. 20:2002;371-394.
42. Sebzda E., Bracke M., Tugal T., Hogg N., Cantrell D.A. Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling. Nat. Immunol. 3:2002;251-258.
43. Shinkai Y., Alt F.W. CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression. Int. Immunol. 6:1994;995-1001.
44. Shinkai Y., Rathbun G., Lam K.P., Oltz E.M., Stewart V., Mendelsohn M., Charron J., Datta M., Young F., Stall A.M.et al. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell. 68:1992;855-867.
45. Storz P., Toker A. Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway. EMBO J. 22:2003;109-120.
46. Sturany S., Van Lint J., Muller F., Wilda M., Hameister H., Hocker M., Brey A., Gern U., Vandenheede J., Gress T.et al. Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinases. J. Biol. Chem. 276:2001;3310-3318.
47. Sturany S., Van Lint J., Gilchrist A., Vandenheede J.R., Adler G., Seufferlein T. Mechanism of activation of protein kinase D2(PKD2) by the CCK(B)/gastrin receptor. J. Biol. Chem. 277:2002;29431-29436.
48. Uematsu Y., Ryser S., Dembic Z., Borgulya P., Krimpenfort P., Berns A., von Boehmer H., Steinmetz M. In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes. Cell. 52:1988;831-841.
49. Valverde A.M., Sinnett-Smith J., Van Lint J., Rozengurt E. Molecular cloning and characterization of protein kinase D. a target for diacylglycerol and phorbol esters with a distinctive catalytic domain Proc. Natl. Acad. Sci. USA. 91:1994;8572-8576.
50. Van Lint J., Rykx A., Maeda Y., Vantus T., Sturany S., Malhotra V., Vandenheede J.R., Seufferlein T. Protein kinase D. an intracellular traffic regulator on the move Trends Cell Biol. 12:2002;193-200.
51. von Boehmer H., Aifantis I., Feinberg J., Lechner O., Saint-Ruf C., Walter U., Buer J., Azogui O. Pleiotropic changes controlled by the pre-T-cell receptor. Curr. Opin. Immunol. 11:1999;135-142.
52. Waldron R.T., Iglesias T., Rozengurt E. Phosphorylation-dependent protein kinase D activation. Electrophoresis. 20:1999;382-390.
53. Waldron R.T., Rey O., Iglesias T., Tugal T., Cantrell D., Rozengurt E. Activation loop Ser744 and Ser748 in protein kinase D are transphosphorylated in vivo. J. Biol. Chem. 276:2001;32606-32615.
54. Wilson A., Capone M., MacDonald H.R. Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development. Int. Immunol. 11:1999;1641-1650.
55. Zhumabekov T., Corbella P., Tolaini M., Kioussis D. Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice. J. Immunol. Methods. 185:1995;133-140.