PH modulation: A mechanism to obtain pH-independent drug release

Expert Opinion on Drug Delivery

Volumn 7, Issue 7, 2010, Pages 845-857

  Bassi, Pallavi ^a   Kaur, Gurpreet ^b  

^a Intellectual Property Rights   (India)

^b PUNJABI UNIVERSITY   (India)

Author keywords

Microenvironment pH modulation; Organic acids; PH independent drug release; Solubility of weak acids and bases

Indexed keywords

4 AMINOPYRIDINE; ADIPIC ACID; ASCORBIC ACID; CITRIC ACID; DIPYRIDAMOLE; EUDRAGIT; EXCIPIENT; FELBINAC; FUMARIC ACID; GLIPIZIDE; HYDROXYPROPYLMETHYLCELLULOSE; INDOMETACIN; KETOPROFEN; MACROGOL 6000; POLYMER; PROPRANOLOL; SORBIC ACID; SUCCINIC ACID; TELMISARTAN; VALPROATE SEMISODIUM; VERAPAMIL; VINPOCETINE;

CONTROLLED DRUG RELEASE; DRUG COATING; DRUG DESIGN; DRUG SOLUBILITY; ENTERIC COATED TABLET; EXCIPIENT COMPATIBILITY; MEAN RESIDENCE TIME; MICELLE; MICELLIZATION; PH; PHYSICAL CHEMISTRY; PKA; REVIEW; SOLUBILIZATION; SUSTAINED RELEASE PREPARATION; DRUG DELIVERY SYSTEM; MEDICINAL CHEMISTRY; SOLUBILITY;

CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; HYDROGEN-ION CONCENTRATION; SOLUBILITY;

EID: 77953852601     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425247.2010.491508     Document Type: Review

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