Influence of enteric citric acid on the release profile of 4-aminopyridine from HPMC matrix tablets

International Journal of Pharmaceutics

Volumn 251, Issue 1-2, 2003, Pages 183-193

  Martínez González, Ilona ^a   Villafuerte Robles, Leopoldo ^a  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

4 Aminopyridine; Enteric citric acid; HPMC; pH effect; Release mechanism

Indexed keywords

4 AMINOPYRIDINE; BUFFER; CITRIC ACID; HYDROCHLORIC ACID; HYDROXYPROPYLMETHYLCELLULOSE; PHOSPHATE; WATER;

ARTICLE; CULTURE MEDIUM; DEVICE; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG GRANULATION; DRUG MIXTURE; DRUG RELEASE; DRUG SOLUBILITY; ENTERIC COATED TABLET; HYDRATION; MATRIX TABLET; MODEL; OBSERVATION; PH; POWDER; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TABLET COMPRESSION;

4-AMINOPYRIDINE; CITRIC ACID; LACTOSE; METHYLCELLULOSE; OXAZINES; SOLUBILITY; TABLETS, ENTERIC-COATED;

EID: 0037472340     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(02)00598-7     Document Type: Article

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