pH-independent release of a basic drug from pellets coated with the extended release polymer dispersion Kollicoat® SR 30 D and the enteric polymer dispersion Kollicoat® MAE 30 DP

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 58, Issue 1, 2004, Pages 45-49

  Dashevsky, A ^a   Kolter, K ^b   Bodmeier, R ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b BASF SE   (Germany)

Author keywords

Enteric polymers; Extended release; Kollicoat SR 30 D; Multiparticulates; pH independent release; Polyvinyl acetate

Indexed keywords

COPOLYMER; MACROGOL; POLY(ETHYL METHACRYLATE); POLYMER; POLYMETHACRYLIC ACID; POLYVINYL ACETATE; VERAPAMIL;

AQUEOUS SOLUTION; ARTICLE; DISPERSIBLE TABLET; DRUG COATING; DRUG RELEASE; DRUG SOLUBILITY; ENTERIC COATED TABLET; PELLET EXTRUSION; PH; PHARMACEUTICAL ENGINEERING;

DELAYED-ACTION PREPARATIONS; DRUG IMPLANTS; HYDROGEN-ION CONCENTRATION; POLYMERS; POLYMETHACRYLIC ACIDS; POLYVINYLS;

EID: 2942637654     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2004.03.013     Document Type: Article

References (16)

1. Thoma K., Ziegler I. pH-independent release of fenoldopam from pellets with insoluble films coats. Eur. J. Pharm. Biopharm. 46:1998;105-113
2. Thoma K., Ziegler I. Simultaneous quantification of released succinic acid and a weakly basic drug compound in dissolution media. Eur. J. Pharm. Biopharm. 46:1998;183-190
3. Oren P.L., Seidler M.K. Sustained release matrix, US patent, 4, 968, 508 Nov. 1990;6
4. Timmins P., Delargy A.M., Howard J.R. Optimization and characterization of a pH independent extended-release hydrophilic matrix tablet. Pharm. Dev. Tech. 2:1997;25-31
5. Espinoza R., Hong E., Villafuerte L. Influence of admixed citric acid in the release profile of pelanserin hydrochloride from HPMC matrix tablets. Int. J. Pharm. 201:2000;165-173
6. Doherty C., York P. Microenviromental pH control of drug dissolution. Int. J. Pharm. 50:1998;223-232
7. Venkatesh G. Development of controlled-release SK and F 82526J buffer bead formulations with tartaric acid as the buffer. Pharm. Dev. Tech. 3:1998;477-485
8. Akiyama Y., Yoshioka M., Horibe H., Hirai S., Kitamori N., Toguchi H. pH-Independent controlled release microspheres using polyglycerol esters of fatty acids. J. Pharm. Sci. 83:1994;1600-1607
9. Gabr K. Effect of organic acids on the release patterns of weekly basic drugs from inert sustained release matrix tablets. Eur. J. Phar. Biopharm. 38:1992;199-202
10. Streubel A., Siepmann J., Dashevsky A., Bodmeier R. pH-independent release of weakly basic drugs from water insoluble and -soluble matrix tablets. J. Control. Rel. 67:2000;101-110
11. Narisawa S., Nagata M., Danyoshi C., Yoshino H., Murata K., Hirakawa Y., Noda K. An organic acid-induced sigmoidal release system for oral controlled-release preparations. Pharm. Res. 11:1994;111-116
12. Narisawa S., Nagata M., Hirakawa Y., Kobayashi M., Yoshino H. An organic acid-induced sigmoidal release system for oral controlled-release preparations. 2. Permeability enhancement of Eudragit RS coating led by the physico-chemical interactions with organic acid. J. Pharm. Sci. 85:1996;184-188
13. Narisawa S., Nagata M., Hirakawa Y., Kobayashi M., Yoshino H. An organic acid-induced sigmoidal release system for oral controlled-release preparations. 3. Elucidation of the anomalous drug release behavior through osmotic pumping mechanism. Int. J. Pharm. 148:1997;85-91
14. G. Benedikt, D. Rango, Arzneiform für Urapidil. Europäische Patentanmeldung EP 0 275 444 A1, 1987.
15. ®SR. AAPS Annual Meeting. 30:1999;384
16. Dressman J.B., Amidon G.L., Reppas C., Shah V.P. Dissolution testing as a prognostic tool for oral drug absorption: Immediate release dosage forms. Pharm. Res. 15:1998;11-22