Strategies for the design of hydrophilic matrix tablets with controlled microenvironmental pH

International Journal of Pharmaceutics

Volumn 316, Issue 1-2, 2006, Pages 14-20

  Siepe, Stefanie ^a,b   Lueckel, Barbara ^a   Kramer, Andrea ^a   Ries, Angelika ^a   Gurny, Robert ^b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Dipyridamole; HPMC; Microenvironmental pH; pH modifier; Weakly basic drug

Indexed keywords

DIPYRIDAMOLE; FUMARIC ACID; HYDROXYPROPYLMETHYLCELLULOSE; PHOSPHATE BUFFERED SALINE;

AQUEOUS SOLUTION; ARTICLE; DISSOLUTION; DRUG RELEASE; MATRIX TABLET; MICROENVIRONMENT; PH; POTENTIOMETRY; PRIORITY JOURNAL;

DRUG DESIGN; HYDROGEN-ION CONCENTRATION; KINETICS; SOLUBILITY; TABLETS, ENTERIC-COATED;

EID: 33747179333     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.02.021     Document Type: Article

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