Properties of hot-melt extruded tablet formulations for the colonic delivery of 5-aminosalicylic acid

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 59, Issue 1, 2005, Pages 85-97

  Bruce, L Diane ^c   Shah, Navnit H ^b   Waseem Malick, A ^b   Infeld, Martin H ^b   McGinity, James W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

^c IQVIA   (United States)

Author keywords

5 ASA; Colonic drug delivery; Eudragit S 100; Hot melt extrusion; Mesalamine; Micro environmental pH; Thermal processing

Indexed keywords

CITRIC ACID; CITRIC ACID TRIETHYL ESTER; DRUG CARRIER; EUDRAGIT; MESALAZINE; PLASTICIZER; POLYMER;

ARTICLE; COLON; CRYSTAL; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DISSOLUTION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; DRUG RELEASE; DRUG TARGETING; EROSION; GLASS TRANSITION TEMPERATURE; IONIZATION; MELTING POINT; MICROENVIRONMENT; PROCESS MODEL; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; X RAY DIFFRACTION;

CHEMISTRY, PHARMACEUTICAL; COLON; DRUG DELIVERY SYSTEMS; MESALAMINE; TABLETS;

EID: 9644279429     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2004.06.007     Document Type: Article

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