메뉴 건너뛰기




Volumn 169, Issue 1, 2010, Pages 532-543

Evidence for the involvement of calbindin D28k in the presenilin 1 model of Alzheimer's disease

Author keywords

Alzheimer's disease; Calbindin D28k; Calcium; Hippocampus; Memory; Synaptic plasticity

Indexed keywords

CALBINDIN; PRESENILIN 1;

EID: 77953808196     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.04.004     Document Type: Article
Times cited : (23)

References (72)
  • 2
    • 0033989375 scopus 로고    scopus 로고
    • Evidence for the involvement of TNF and NF-kappaB in hippocampal synaptic plasticity
    • Albensi B.C., Mattson M.P. Evidence for the involvement of TNF and NF-kappaB in hippocampal synaptic plasticity. Synapse 2000, 35:151-159.
    • (2000) Synapse , vol.35 , pp. 151-159
    • Albensi, B.C.1    Mattson, M.P.2
  • 3
    • 0034667728 scopus 로고    scopus 로고
    • Long-term potentiation in the presence of NMDA receptor antagonist arylalkylamine spider toxins
    • Albensi B.C., Alasti N., Mueller A.L. Long-term potentiation in the presence of NMDA receptor antagonist arylalkylamine spider toxins. J Neurosci Res 2000, 62:177-185.
    • (2000) J Neurosci Res , vol.62 , pp. 177-185
    • Albensi, B.C.1    Alasti, N.2    Mueller, A.L.3
  • 6
    • 0027476024 scopus 로고
    • A synaptic model of memory: long-term potentiation in the hippocampus
    • Bliss T.V., Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 1993, 361:31-39.
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 7
    • 30444454374 scopus 로고    scopus 로고
    • Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury
    • Brody D.L., Holtzman D.M. Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury. Exp Neurol 2006, 197:330-340.
    • (2006) Exp Neurol , vol.197 , pp. 330-340
    • Brody, D.L.1    Holtzman, D.M.2
  • 8
    • 18844378852 scopus 로고    scopus 로고
    • Presenilin function and gamma-secretase activity
    • Brunkan A.L., Goate A.M. Presenilin function and gamma-secretase activity. J Neurochem 2005, 93:769-792.
    • (2005) J Neurochem , vol.93 , pp. 769-792
    • Brunkan, A.L.1    Goate, A.M.2
  • 9
    • 0034674730 scopus 로고    scopus 로고
    • Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons
    • Chan S.L., Mayne M., Holden C.P., Geiger J.D., Mattson M.P. Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons. J Biol Chem 2000, 275:18195-18200.
    • (2000) J Biol Chem , vol.275 , pp. 18195-18200
    • Chan, S.L.1    Mayne, M.2    Holden, C.P.3    Geiger, J.D.4    Mattson, M.P.5
  • 10
    • 0036049185 scopus 로고    scopus 로고
    • Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease
    • Chan S.L., Furukawa K., Mattson M.P. Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease. Neuromolecular Med 2002, 2:167-196.
    • (2002) Neuromolecular Med , vol.2 , pp. 167-196
    • Chan, S.L.1    Furukawa, K.2    Mattson, M.P.3
  • 14
    • 0034888287 scopus 로고    scopus 로고
    • Applications of the morris water maze in the study of learning and memory
    • D'Hooge R., De Deyn P.P. Applications of the morris water maze in the study of learning and memory. Brain Res Brain Res Rev 2001, 36:60-90.
    • (2001) Brain Res Brain Res Rev , vol.36 , pp. 60-90
    • D'Hooge, R.1    De Deyn, P.P.2
  • 17
    • 0030851335 scopus 로고    scopus 로고
    • Alzheimer transgenic mouse models come of age
    • Duff K. Alzheimer transgenic mouse models come of age. Trends Neurosci 1997, 20:279-280.
    • (1997) Trends Neurosci , vol.20 , pp. 279-280
    • Duff, K.1
  • 18
    • 4544343893 scopus 로고    scopus 로고
    • Overexpression of calbindin d(28k) in dentate gyrus granule cells alters mossy fiber presynaptic function and impairs hippocampal-dependent memory
    • Dumas T.C., Powers E.C., Tarapore P.E., Sapolsky R.M. Overexpression of calbindin d(28k) in dentate gyrus granule cells alters mossy fiber presynaptic function and impairs hippocampal-dependent memory. Hippocampus 2004, 14:701-709.
    • (2004) Hippocampus , vol.14 , pp. 701-709
    • Dumas, T.C.1    Powers, E.C.2    Tarapore, P.E.3    Sapolsky, R.M.4
  • 19
    • 33947541241 scopus 로고    scopus 로고
    • Pretreatment with PTD-calbindin d 28k alleviates rat brain injury induced by ischemia and reperfusion
    • Fan Y., Shi L., Gu Y., Zhao Y., Xie J., Qiao J., Yang G.Y., Wang Y., Lu C.Z. Pretreatment with PTD-calbindin d 28k alleviates rat brain injury induced by ischemia and reperfusion. J Cereb Blood Flow Metab 2007, 27:719-728.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 719-728
    • Fan, Y.1    Shi, L.2    Gu, Y.3    Zhao, Y.4    Xie, J.5    Qiao, J.6    Yang, G.Y.7    Wang, Y.8    Lu, C.Z.9
  • 20
    • 0033785307 scopus 로고    scopus 로고
    • Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors
    • Fujii S., Matsumoto M., Igarashi K., Kato H., Mikoshiba K. Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors. Learn Mem 2000, 7:312-320.
    • (2000) Learn Mem , vol.7 , pp. 312-320
    • Fujii, S.1    Matsumoto, M.2    Igarashi, K.3    Kato, H.4    Mikoshiba, K.5
  • 22
    • 0027499734 scopus 로고
    • Calbindin-d28k immunoreactivity and selective vulnerability to ischemia in the dentate gyrus of the developing rat
    • Goodman J.H., Wasterlain C.G., Massarweh W.F., Dean E., Sollas A.L., Sloviter R.S. Calbindin-d28k immunoreactivity and selective vulnerability to ischemia in the dentate gyrus of the developing rat. Brain Res 1993, 606:309-314.
    • (1993) Brain Res , vol.606 , pp. 309-314
    • Goodman, J.H.1    Wasterlain, C.G.2    Massarweh, W.F.3    Dean, E.4    Sollas, A.L.5    Sloviter, R.S.6
  • 23
    • 58149267462 scopus 로고    scopus 로고
    • Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau
    • Green K.N., Steffan J.S., Martinez-Coria H., Sun X., Schreiber S.S., Thompson L.M., LaFerla F.M. Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. J Neurosci 2008, 28:11500-11510.
    • (2008) J Neurosci , vol.28 , pp. 11500-11510
    • Green, K.N.1    Steffan, J.S.2    Martinez-Coria, H.3    Sun, X.4    Schreiber, S.S.5    Thompson, L.M.6    LaFerla, F.M.7
  • 24
    • 46249123354 scopus 로고    scopus 로고
    • Serca pump activity is physiologically regulated by presenilin and regulates amyloid beta production
    • Green K.N., Demuro A., Akbari Y., Hitt B.D., Smith I.F., Parker I., LaFerla F.M. Serca pump activity is physiologically regulated by presenilin and regulates amyloid beta production. J Cell Biol 2008, 181:1107-1116.
    • (2008) J Cell Biol , vol.181 , pp. 1107-1116
    • Green, K.N.1    Demuro, A.2    Akbari, Y.3    Hitt, B.D.4    Smith, I.F.5    Parker, I.6    LaFerla, F.M.7
  • 25
    • 0033016172 scopus 로고    scopus 로고
    • Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
    • Guo Q., Fu W., Sopher B.L., Miller M.W., Ware C.B., Martin G.M., Mattson M.P. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat Med 1999, 5:101-106.
    • (1999) Nat Med , vol.5 , pp. 101-106
    • Guo, Q.1    Fu, W.2    Sopher, B.L.3    Miller, M.W.4    Ware, C.B.5    Martin, G.M.6    Mattson, M.P.7
  • 26
    • 0033616796 scopus 로고    scopus 로고
    • Neurotrophic factors [activity-dependent neurotrophic factor (adnf) and basic fibroblast growth factor (bfgf)] interrupt excitotoxic neurodegenerative cascades promoted by a ps1 mutation
    • Guo Q., Sebastian L., Sopher B.L., Miller M.W., Glazner G.W., Ware C.B., Martin G.M., Mattson M.P. Neurotrophic factors [activity-dependent neurotrophic factor (adnf) and basic fibroblast growth factor (bfgf)] interrupt excitotoxic neurodegenerative cascades promoted by a ps1 mutation. Proc Natl Acad Sci U S A 1999, 96:4125-4130.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4125-4130
    • Guo, Q.1    Sebastian, L.2    Sopher, B.L.3    Miller, M.W.4    Glazner, G.W.5    Ware, C.B.6    Martin, G.M.7    Mattson, M.P.8
  • 27
    • 25144491224 scopus 로고    scopus 로고
    • Simultaneous glutamate and GABA(A) receptor agonist administration increases calbindin levels and prevents hippocampal damage induced by either agent alone in a model of perinatal brain injury
    • Hilton G.D., Ndubuizu A., Nunez J.L., McCarthy M.M. Simultaneous glutamate and GABA(A) receptor agonist administration increases calbindin levels and prevents hippocampal damage induced by either agent alone in a model of perinatal brain injury. Brain Res Dev Brain Res 2005, 159:99-111.
    • (2005) Brain Res Dev Brain Res , vol.159 , pp. 99-111
    • Hilton, G.D.1    Ndubuizu, A.2    Nunez, J.L.3    McCarthy, M.M.4
  • 28
    • 0025969656 scopus 로고
    • Neocortical neuronal subpopulations labeled by a monoclonal antibody to calbindin exhibit differential vulnerability in Alzheimer's disease
    • Hof P.R., Morrison J.H. Neocortical neuronal subpopulations labeled by a monoclonal antibody to calbindin exhibit differential vulnerability in Alzheimer's disease. Exp Neurol 1991, 111:293-301.
    • (1991) Exp Neurol , vol.111 , pp. 293-301
    • Hof, P.R.1    Morrison, J.H.2
  • 29
    • 0141448940 scopus 로고    scopus 로고
    • Behavioral and neurochemical characterization of transgenic mice carrying the human presenilin-1 gene with or without the leucine-to-proline mutation at codon 235
    • Huang X.G., Yee B.K., Nag S., Chan S.T., Tang F. Behavioral and neurochemical characterization of transgenic mice carrying the human presenilin-1 gene with or without the leucine-to-proline mutation at codon 235. Exp Neurol 2003, 183:673-681.
    • (2003) Exp Neurol , vol.183 , pp. 673-681
    • Huang, X.G.1    Yee, B.K.2    Nag, S.3    Chan, S.T.4    Tang, F.5
  • 31
    • 2542622162 scopus 로고    scopus 로고
    • Search strategies used by app transgenic mice during navigation in the morris water maze
    • Janus C. Search strategies used by app transgenic mice during navigation in the morris water maze. Learn Mem 2004, 11:337-346.
    • (2004) Learn Mem , vol.11 , pp. 337-346
    • Janus, C.1
  • 34
    • 17644370721 scopus 로고    scopus 로고
    • Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease
    • Kobayashi D.T., Chen K.S. Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease. Genes Brain Behav 2005, 4:173-196.
    • (2005) Genes Brain Behav , vol.4 , pp. 173-196
    • Kobayashi, D.T.1    Chen, K.S.2
  • 35
    • 0034629264 scopus 로고    scopus 로고
    • Mutant mice lacking ryanodine receptor type 3 exhibit deficits of contextual fear conditioning and activation of calcium/calmodulin-dependent protein kinase II in the hippocampus
    • Kouzu Y., Moriya T., Takeshima H., Yoshioka T., Shibata S. Mutant mice lacking ryanodine receptor type 3 exhibit deficits of contextual fear conditioning and activation of calcium/calmodulin-dependent protein kinase II in the hippocampus. Brain Res Mol Brain Res 2000, 76:142-150.
    • (2000) Brain Res Mol Brain Res , vol.76 , pp. 142-150
    • Kouzu, Y.1    Moriya, T.2    Takeshima, H.3    Yoshioka, T.4    Shibata, S.5
  • 36
    • 32544455089 scopus 로고    scopus 로고
    • Expression of a familial Alzheimer's disease-linked presenilin-1 variant enhances perforant pathway lesion-induced neuronal loss in the entorhinal cortex
    • Lazarov O., Peterson L.D., Peterson D.A., Sisodia S.S. Expression of a familial Alzheimer's disease-linked presenilin-1 variant enhances perforant pathway lesion-induced neuronal loss in the entorhinal cortex. J Neurosci 2006, 26:429-434.
    • (2006) J Neurosci , vol.26 , pp. 429-434
    • Lazarov, O.1    Peterson, L.D.2    Peterson, D.A.3    Sisodia, S.S.4
  • 38
    • 0030921483 scopus 로고    scopus 로고
    • Blind rats are not profoundly impaired in the reference memory Morris water maze and cannot be clearly discriminated from rats with cognitive deficits in the cued platform task
    • Lindner M.D., Plone M.A., Schallert T., Emerich D.F. Blind rats are not profoundly impaired in the reference memory Morris water maze and cannot be clearly discriminated from rats with cognitive deficits in the cued platform task. Brain Res Cogn Brain Res 1997, 5:329-333.
    • (1997) Brain Res Cogn Brain Res , vol.5 , pp. 329-333
    • Lindner, M.D.1    Plone, M.A.2    Schallert, T.3    Emerich, D.F.4
  • 39
    • 0031281862 scopus 로고    scopus 로고
    • Reliability, distribution, and validity of age-related cognitive deficits in the morris water maze
    • Lindner M.D. Reliability, distribution, and validity of age-related cognitive deficits in the morris water maze. Neurobiol Learn Mem 1997, 68:203-220.
    • (1997) Neurobiol Learn Mem , vol.68 , pp. 203-220
    • Lindner, M.D.1
  • 40
    • 17644382712 scopus 로고    scopus 로고
    • Invertebrate models of Alzheimer's disease
    • Link C.D. Invertebrate models of Alzheimer's disease. Genes Brain Behav 2005, 4:147-156.
    • (2005) Genes Brain Behav , vol.4 , pp. 147-156
    • Link, C.D.1
  • 41
    • 0032052679 scopus 로고    scopus 로고
    • Genetically modified mice and cognition
    • Lipp H.P., Wolfer D.P. Genetically modified mice and cognition. Curr Opin Neurobiol 1998, 8:272-280.
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 272-280
    • Lipp, H.P.1    Wolfer, D.P.2
  • 42
    • 17644419726 scopus 로고    scopus 로고
    • Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation
    • Marambaud P., Robakis N.K. Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation. Genes Brain Behav 2005, 4:134-146.
    • (2005) Genes Brain Behav , vol.4 , pp. 134-146
    • Marambaud, P.1    Robakis, N.K.2
  • 43
    • 0034042406 scopus 로고    scopus 로고
    • Synaptic plasticity and memory: an evaluation of the hypothesis
    • Martin S.J., Grimwood P.D., Morris R.G. Synaptic plasticity and memory: an evaluation of the hypothesis. Annu Rev Neurosci 2000, 23:649-711.
    • (2000) Annu Rev Neurosci , vol.23 , pp. 649-711
    • Martin, S.J.1    Grimwood, P.D.2    Morris, R.G.3
  • 44
    • 0026069449 scopus 로고
    • Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-d28k in cultured hippocampal neurons
    • Mattson M.P., Rychlik B., Chu C., Christakos S. Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-d28k in cultured hippocampal neurons. Neuron 1991, 6:41-51.
    • (1991) Neuron , vol.6 , pp. 41-51
    • Mattson, M.P.1    Rychlik, B.2    Chu, C.3    Christakos, S.4
  • 46
    • 0034607613 scopus 로고    scopus 로고
    • Developmental changes in expression of the three ryanodine receptor mrnas in the mouse brain
    • Mori F., Fukaya M., Abe H., Wakabayashi K., Watanabe M. Developmental changes in expression of the three ryanodine receptor mrnas in the mouse brain. Neurosci Lett 2000, 285:57-60.
    • (2000) Neurosci Lett , vol.285 , pp. 57-60
    • Mori, F.1    Fukaya, M.2    Abe, H.3    Wakabayashi, K.4    Watanabe, M.5
  • 47
    • 0033635857 scopus 로고    scopus 로고
    • Binding kinetics of calbindin-d(28k) determined by flash photolysis of caged ca(2+)
    • Nagerl U.V., Novo D., Mody I., Vergara J.L. Binding kinetics of calbindin-d(28k) determined by flash photolysis of caged ca(2+). Biophys J 2000, 79:3009-3018.
    • (2000) Biophys J , vol.79 , pp. 3009-3018
    • Nagerl, U.V.1    Novo, D.2    Mody, I.3    Vergara, J.L.4
  • 48
    • 0033005161 scopus 로고    scopus 로고
    • Biology of presenilins as causative molecules for Alzheimer disease
    • Nishimura M., Yu G., St George-Hyslop P.H. Biology of presenilins as causative molecules for Alzheimer disease. Clin Genet 1999, 55:219-225.
    • (1999) Clin Genet , vol.55 , pp. 219-225
    • Nishimura, M.1    Yu, G.2    St George-Hyslop, P.H.3
  • 50
    • 0032945724 scopus 로고    scopus 로고
    • Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1
    • Parent A., Linden D.J., Sisodia S.S., Borchelt D.R. Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1. Neurobiol Dis 1999, 6:56-62.
    • (1999) Neurobiol Dis , vol.6 , pp. 56-62
    • Parent, A.1    Linden, D.J.2    Sisodia, S.S.3    Borchelt, D.R.4
  • 54
    • 0038417858 scopus 로고    scopus 로고
    • Enhanced long-term potentiation in the hippocampus of rats expressing mutant presenillin-1 is age related
    • Pybus R., Barnard E., Estibeiro P., Mullins J., MacLeod N. Enhanced long-term potentiation in the hippocampus of rats expressing mutant presenillin-1 is age related. Neurobiol Dis 2003, 12:212-224.
    • (2003) Neurobiol Dis , vol.12 , pp. 212-224
    • Pybus, R.1    Barnard, E.2    Estibeiro, P.3    Mullins, J.4    MacLeod, N.5
  • 55
    • 0036310603 scopus 로고    scopus 로고
    • Different calcium sources are narrowly tuned to the induction of different forms of LTP
    • Raymond C.R., Redman S.J. Different calcium sources are narrowly tuned to the induction of different forms of LTP. J Neurophysiol 2002, 88:249-255.
    • (2002) J Neurophysiol , vol.88 , pp. 249-255
    • Raymond, C.R.1    Redman, S.J.2
  • 56
    • 35748954015 scopus 로고    scopus 로고
    • The cytosolic n-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity
    • Rybalchenko V., Hwang S.Y., Rybalchenko N., Koulen P. The cytosolic n-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity. Int J Biochem Cell Biol 2008, 40:84-97.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 84-97
    • Rybalchenko, V.1    Hwang, S.Y.2    Rybalchenko, N.3    Koulen, P.4
  • 57
    • 36048980002 scopus 로고    scopus 로고
    • NF-kappaB activated by ER calcium release inhibits Abeta-mediated expression of chop protein: enhancement by AD-linked mutant presenilin 1
    • Schapansky J., Olson K., Van Der Ploeg R., Glazner G. NF-kappaB activated by ER calcium release inhibits Abeta-mediated expression of chop protein: enhancement by AD-linked mutant presenilin 1. Exp Neurol 2007, 208:169-176.
    • (2007) Exp Neurol , vol.208 , pp. 169-176
    • Schapansky, J.1    Olson, K.2    Van Der Ploeg, R.3    Glazner, G.4
  • 59
    • 0034518216 scopus 로고    scopus 로고
    • The genetics and molecular pathology of Alzheimer's disease: roles of amyloid and the presenilins
    • Selkoe D.J. The genetics and molecular pathology of Alzheimer's disease: roles of amyloid and the presenilins. Neurol Clin 2000, 18:903-922.
    • (2000) Neurol Clin , vol.18 , pp. 903-922
    • Selkoe, D.J.1
  • 60
    • 0034981773 scopus 로고    scopus 로고
    • Postsynaptic modulation of AMPA receptor-mediated synaptic responses and LTP by the type 3 ryanodine receptor
    • Shimuta M., Yoshikawa M., Fukaya M., Watanabe M., Takeshima H., Manabe T. Postsynaptic modulation of AMPA receptor-mediated synaptic responses and LTP by the type 3 ryanodine receptor. Mol Cell Neurosci 2001, 17:921-930.
    • (2001) Mol Cell Neurosci , vol.17 , pp. 921-930
    • Shimuta, M.1    Yoshikawa, M.2    Fukaya, M.3    Watanabe, M.4    Takeshima, H.5    Manabe, T.6
  • 61
    • 24644456470 scopus 로고    scopus 로고
    • Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals
    • Smith I.F., Green K.N., LaFerla F.M. Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals. Cell Calcium 2005, 38:427-437.
    • (2005) Cell Calcium , vol.38 , pp. 427-437
    • Smith, I.F.1    Green, K.N.2    LaFerla, F.M.3
  • 62
    • 24644460177 scopus 로고    scopus 로고
    • Enhanced caffeine-induced Ca2+ release in the 3xtg-ad mouse model of Alzheimer's disease
    • Smith I.F., Hitt B., Green K.N., Oddo S., LaFerla F.M. Enhanced caffeine-induced Ca2+ release in the 3xtg-ad mouse model of Alzheimer's disease. J Neurochem 2005, 94:1711-1718.
    • (2005) J Neurochem , vol.94 , pp. 1711-1718
    • Smith, I.F.1    Hitt, B.2    Green, K.N.3    Oddo, S.4    LaFerla, F.M.5
  • 63
    • 13844255273 scopus 로고    scopus 로고
    • Molecular biology and genetics of Alzheimer's disease
    • St George-Hyslop P.H., Petit A. Molecular biology and genetics of Alzheimer's disease. C R Biol 2005, 328:119-130.
    • (2005) C R Biol , vol.328 , pp. 119-130
    • St George-Hyslop, P.H.1    Petit, A.2
  • 64
    • 42149182981 scopus 로고    scopus 로고
    • The catalytic core of gamma-secretase: presenilin revisited
    • Steiner H. The catalytic core of gamma-secretase: presenilin revisited. Curr Alzheimer Res 2008, 5:147-157.
    • (2008) Curr Alzheimer Res , vol.5 , pp. 147-157
    • Steiner, H.1
  • 65
    • 1342288871 scopus 로고    scopus 로고
    • Dysregulated ip3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability
    • Stutzmann G.E., Caccamo A., LaFerla F.M., Parker I. Dysregulated ip3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability. J Neurosci 2004, 24:508-513.
    • (2004) J Neurosci , vol.24 , pp. 508-513
    • Stutzmann, G.E.1    Caccamo, A.2    LaFerla, F.M.3    Parker, I.4
  • 66
    • 34247621471 scopus 로고    scopus 로고
    • Enhanced ryanodine-mediated calcium release in mutant ps1-expressing Alzheimer's mouse models
    • Stutzmann G.E., Smith I., Caccamo A., Oddo S., Parker I., Laferla F. Enhanced ryanodine-mediated calcium release in mutant ps1-expressing Alzheimer's mouse models. Ann N Y Acad Sci 2007, 1097:265-277.
    • (2007) Ann N Y Acad Sci , vol.1097 , pp. 265-277
    • Stutzmann, G.E.1    Smith, I.2    Caccamo, A.3    Oddo, S.4    Parker, I.5    Laferla, F.6
  • 67
    • 23844532257 scopus 로고    scopus 로고
    • Hippocampal spatial memory impairments caused by the familial Alzheimer's disease-linked presenilin 1 m146v mutation
    • Sun X., Beglopoulos V., Mattson M.P., Shen J. Hippocampal spatial memory impairments caused by the familial Alzheimer's disease-linked presenilin 1 m146v mutation. Neurodegener Dis 2005, 2:6-15.
    • (2005) Neurodegener Dis , vol.2 , pp. 6-15
    • Sun, X.1    Beglopoulos, V.2    Mattson, M.P.3    Shen, J.4
  • 71
    • 0034095106 scopus 로고    scopus 로고
    • Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine
    • Zaman S.H., Parent A., Laskey A., Lee M.K., Borchelt D.R., Sisodia S.S., Malinow R. Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine. Neurobiol Dis 2000, 7:54-63.
    • (2000) Neurobiol Dis , vol.7 , pp. 54-63
    • Zaman, S.H.1    Parent, A.2    Laskey, A.3    Lee, M.K.4    Borchelt, D.R.5    Sisodia, S.S.6    Malinow, R.7
  • 72
    • 0024600340 scopus 로고
    • Short-term synaptic plasticity
    • Zucker R.S. Short-term synaptic plasticity. Annu Rev Neurosci 1989, 12:13-31.
    • (1989) Annu Rev Neurosci , vol.12 , pp. 13-31
    • Zucker, R.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.