메뉴 건너뛰기




Volumn 239, Issue 2, 2006, Pages 298-304

Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 mice

Author keywords

Adhesion; Ajoene; Melanoma; Metastasis; Tumor

Indexed keywords

AJOENE; INTRALIPID; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 33745667762     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2005.08.022     Document Type: Article
Times cited : (57)

References (35)
  • 1
    • 0030029823 scopus 로고    scopus 로고
    • Therapeutic actions of garlic constituents
    • Agarwal K.C. Therapeutic actions of garlic constituents. Med. Res. Rev. 16 (1996) 111-124
    • (1996) Med. Res. Rev. , vol.16 , pp. 111-124
    • Agarwal, K.C.1
  • 3
    • 0035126524 scopus 로고    scopus 로고
    • Antiproliferative effects of allium derivatives from garlic
    • Pinto J.T., and Rivlin R.S. Antiproliferative effects of allium derivatives from garlic. J. Nutr. 131 (2001) 1058S-1060S
    • (2001) J. Nutr. , vol.131
    • Pinto, J.T.1    Rivlin, R.S.2
  • 4
    • 0034913273 scopus 로고    scopus 로고
    • Antiproliferative effects of garlic-derived and other allium related compounds
    • Pinto J.T., Lapsia S., Shah A., Santiago H., and Kim G. Antiproliferative effects of garlic-derived and other allium related compounds. Adv. Exp. Med. Biol. 492 (2001) 83-106
    • (2001) Adv. Exp. Med. Biol. , vol.492 , pp. 83-106
    • Pinto, J.T.1    Lapsia, S.2    Shah, A.3    Santiago, H.4    Kim, G.5
  • 5
    • 0023749116 scopus 로고
    • Reversible prevention of platelet activation by (E,Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxide (ajoene) in dogs under extracorporeal circulation
    • Apitz C., Ledezma E., Escalante J., Jorquera A., Pinate F.M., Moreno R., et al. Reversible prevention of platelet activation by (E,Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxide (ajoene) in dogs under extracorporeal circulation. Fortschr. Arzneimittelforsch. 38 (1988) 901-914
    • (1988) Fortschr. Arzneimittelforsch. , vol.38 , pp. 901-914
    • Apitz, C.1    Ledezma, E.2    Escalante, J.3    Jorquera, A.4    Pinate, F.M.5    Moreno, R.6
  • 6
    • 0028104072 scopus 로고
    • A garlic derivative, ajoene, inhibits platelet deposition on severely damaged vessel wall in an in vivo porcine experimental model
    • Apitz-Castro R., Badimon J.J., and Badimon L. A garlic derivative, ajoene, inhibits platelet deposition on severely damaged vessel wall in an in vivo porcine experimental model. Thromb. Res. 75 (1994) 243-249
    • (1994) Thromb. Res. , vol.75 , pp. 243-249
    • Apitz-Castro, R.1    Badimon, J.J.2    Badimon, L.3
  • 7
    • 0026494991 scopus 로고
    • Effect of ajoene, the major antiplatelet compound from garlic, on platelet thrombus formation
    • Apitz-Castro R., Badimon J.J., and Badimon L. Effect of ajoene, the major antiplatelet compound from garlic, on platelet thrombus formation. Thromb. Res. 68 (1992) 145-155
    • (1992) Thromb. Res. , vol.68 , pp. 145-155
    • Apitz-Castro, R.1    Badimon, J.J.2    Badimon, L.3
  • 8
    • 0031830565 scopus 로고    scopus 로고
    • Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase
    • Dirsch V.M., Kiemer A.K., Wagner H., and Vollmar A.M. Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase. Atherosclerosis 139 (1998) 333-339
    • (1998) Atherosclerosis , vol.139 , pp. 333-339
    • Dirsch, V.M.1    Kiemer, A.K.2    Wagner, H.3    Vollmar, A.M.4
  • 9
    • 0035282656 scopus 로고    scopus 로고
    • Ajoene, a natural product with non-steroidal anti-inflammatory drug (NSAID)-like properties?
    • Dirsch V.M., and Vollmar A.M. Ajoene, a natural product with non-steroidal anti-inflammatory drug (NSAID)-like properties?. Biochem. Pharmacol. 61 (2001) 587-593
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 587-593
    • Dirsch, V.M.1    Vollmar, A.M.2
  • 11
    • 0022902577 scopus 로고
    • The molecular basis of the antiplatelet action of ajoene: direct interaction with the fibrinogen receptor
    • Apitz C., Ledezma E., Escalante J., and Jain M.K. The molecular basis of the antiplatelet action of ajoene: direct interaction with the fibrinogen receptor. Biochem. Biophys. Res. Comm. 141 (1986) 145-150
    • (1986) Biochem. Biophys. Res. Comm. , vol.141 , pp. 145-150
    • Apitz, C.1    Ledezma, E.2    Escalante, J.3    Jain, M.K.4
  • 12
  • 13
    • 0042367714 scopus 로고    scopus 로고
    • Ajoene inhibits the activation of human endothelial cells induced by porcine cells: implications for xenotransplantation
    • Benatuil L., Apitz C., and Romano E. Ajoene inhibits the activation of human endothelial cells induced by porcine cells: implications for xenotransplantation. Xenotransplantation 10 (2003) 368-373
    • (2003) Xenotransplantation , vol.10 , pp. 368-373
    • Benatuil, L.1    Apitz, C.2    Romano, E.3
  • 15
    • 0035127032 scopus 로고    scopus 로고
    • A historical perspective on garlic and cancer
    • Milner J.A. A historical perspective on garlic and cancer. J. Nutr. 131 (2001) 1027S-1031S
    • (2001) J. Nutr. , vol.131
    • Milner, J.A.1
  • 16
    • 0033879654 scopus 로고    scopus 로고
    • Structure-activity relationships for selected sulfur-rich antithrombotic compounds
    • MacDonald J.A., and Langler R.F. Structure-activity relationships for selected sulfur-rich antithrombotic compounds. Biochem. Biophys. Res. Comm. 273 (2000) 421-424
    • (2000) Biochem. Biophys. Res. Comm. , vol.273 , pp. 421-424
    • MacDonald, J.A.1    Langler, R.F.2
  • 17
    • 1442335377 scopus 로고    scopus 로고
    • Apoptotic and anti-adhesion effect of ajoene, a garlic derived compound, on the murine melanoma B16F10 cells: possible role of caspase-3 and the alpha(4)beta(1) integrin
    • Ledezma E., Apitz C., and Cardier J. Apoptotic and anti-adhesion effect of ajoene, a garlic derived compound, on the murine melanoma B16F10 cells: possible role of caspase-3 and the alpha(4)beta(1) integrin. Cancer Lett. 206 (2004) 35-41
    • (2004) Cancer Lett. , vol.206 , pp. 35-41
    • Ledezma, E.1    Apitz, C.2    Cardier, J.3
  • 18
    • 0036257468 scopus 로고    scopus 로고
    • Antitumor activity of Z-ajoene, a natural compound purified from garlic: antimitotic and microtubule-interaction properties
    • Li M., Ciu J.R., Ye Y., Min J.M., Zhang L.H., Wang K., et al. Antitumor activity of Z-ajoene, a natural compound purified from garlic: antimitotic and microtubule-interaction properties. Carcinogenesis 23 (2002) 573-579
    • (2002) Carcinogenesis , vol.23 , pp. 573-579
    • Li, M.1    Ciu, J.R.2    Ye, Y.3    Min, J.M.4    Zhang, L.H.5    Wang, K.6
  • 19
    • 0025006711 scopus 로고
    • The cytotoxic effect of ajoene, a natural product from garlic, investigated with different cell lines
    • Scharfenberg K., Wagner R., and Wagner K.G. The cytotoxic effect of ajoene, a natural product from garlic, investigated with different cell lines. Cancer Lett. 53 (1990) 103-108
    • (1990) Cancer Lett. , vol.53 , pp. 103-108
    • Scharfenberg, K.1    Wagner, R.2    Wagner, K.G.3
  • 21
    • 0023556471 scopus 로고
    • American Association of Pathologists president's address. New roles for the endothelium in inflammation and immunity
    • Cotran R.S. American Association of Pathologists president's address. New roles for the endothelium in inflammation and immunity. Am. J. Pathol. 129 (1987) 407-413
    • (1987) Am. J. Pathol. , vol.129 , pp. 407-413
    • Cotran, R.S.1
  • 22
    • 0025745052 scopus 로고
    • Effect of inflammatory cytokines on the adherence of tumor cells to endothelium in a murine model
    • Bereta M., Bereta J., Cohen S., Zaifert K., and Cohen M.C. Effect of inflammatory cytokines on the adherence of tumor cells to endothelium in a murine model. Cell. Immunol. 136 (1991) 263-269
    • (1991) Cell. Immunol. , vol.136 , pp. 263-269
    • Bereta, M.1    Bereta, J.2    Cohen, S.3    Zaifert, K.4    Cohen, M.C.5
  • 24
    • 0024238518 scopus 로고
    • Tumor cell-endothelial interactions. Increased adhesion of human melanoma cells to activated vascular endothelium
    • Rice G.E., Gimbrone Jr. M.A., and Bevilacqua M.P. Tumor cell-endothelial interactions. Increased adhesion of human melanoma cells to activated vascular endothelium. Am. J. Pathol. 133 (1988) 204-210
    • (1988) Am. J. Pathol. , vol.133 , pp. 204-210
    • Rice, G.E.1    Gimbrone Jr., M.A.2    Bevilacqua, M.P.3
  • 25
    • 0027026622 scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill F.R. Tumour necrosis factor and cancer. Prog. Growth Factor Res. 4 (1992) 121-123
    • (1992) Prog. Growth Factor Res. , vol.4 , pp. 121-123
    • Balkwill, F.R.1
  • 27
    • 0030812192 scopus 로고    scopus 로고
    • Effect of blocking TNF on IL-6 levels and metastasis in a B16-BL6 melanoma/mouse model
    • Cubillos S., Scallon B., Feldmann M., and Taylor P. Effect of blocking TNF on IL-6 levels and metastasis in a B16-BL6 melanoma/mouse model. Anticancer Res. 17 (1997) 2207-2211
    • (1997) Anticancer Res. , vol.17 , pp. 2207-2211
    • Cubillos, S.1    Scallon, B.2    Feldmann, M.3    Taylor, P.4
  • 28
    • 0037301861 scopus 로고    scopus 로고
    • Garlic [Allium sativum]: a review of its potential use as an anti-cancer agent
    • Thomson M., and Ali M. Garlic [Allium sativum]: a review of its potential use as an anti-cancer agent. Curr. Cancer Drug Targets 3 (2003) 67-81
    • (2003) Curr. Cancer Drug Targets , vol.3 , pp. 67-81
    • Thomson, M.1    Ali, M.2
  • 29
    • 0042659566 scopus 로고    scopus 로고
    • The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis
    • Tilli C.M., Stavast K., Vuerstaek J.D., Thissen M.R., Krekels G.A., Ramaekers F.C., et al. The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis. Arch. Dermatol. Res. 295 (2003) 117
    • (2003) Arch. Dermatol. Res. , vol.295 , pp. 117
    • Tilli, C.M.1    Stavast, K.2    Vuerstaek, J.D.3    Thissen, M.R.4    Krekels, G.A.5    Ramaekers, F.C.6
  • 30
    • 0024041642 scopus 로고
    • Amplified expression of the HER2/ERBB2 oncogene induces resistance to tumor necrosis factor alpha in NIH 3T3 cells
    • Hudziak R.M., Lewis G.D., Shalaby M.R., Eessalu T.E., Aggarwal B.B., Ullrich A., et al. Amplified expression of the HER2/ERBB2 oncogene induces resistance to tumor necrosis factor alpha in NIH 3T3 cells. Proc. Natl. Acad. Sci. USA 85 (1988) 5102-5106
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5102-5106
    • Hudziak, R.M.1    Lewis, G.D.2    Shalaby, M.R.3    Eessalu, T.E.4    Aggarwal, B.B.5    Ullrich, A.6
  • 31
    • 0023430930 scopus 로고
    • Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells
    • Hudziak R.M., Schlessinger J., and Ullrich A. Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells. Proc. Natl. Acad. Sci. USA 84 (1987) 7159-7163
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7159-7163
    • Hudziak, R.M.1    Schlessinger, J.2    Ullrich, A.3
  • 32
    • 0031976715 scopus 로고    scopus 로고
    • Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB
    • Dirsch V.M., Gerbes A.L., and Vollmar A.M. Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB. Mol. Pharmacol. 53 (1998) 402-407
    • (1998) Mol. Pharmacol. , vol.53 , pp. 402-407
    • Dirsch, V.M.1    Gerbes, A.L.2    Vollmar, A.M.3
  • 34
    • 0017644933 scopus 로고
    • Platelet-cancer cell interaction in metastasis formation: a possible therapeutic approcach to metastasis prophylaxis
    • Gastpar H. Platelet-cancer cell interaction in metastasis formation: a possible therapeutic approcach to metastasis prophylaxis. J. Med. 8 (1977) 103-114
    • (1977) J. Med. , vol.8 , pp. 103-114
    • Gastpar, H.1
  • 35
    • 0026445242 scopus 로고
    • Cancer cell interactions with injured or activated endothelium
    • Lafrenie R., Shaughnessy S.G., and Orr F.W. Cancer cell interactions with injured or activated endothelium. Cancer Metastasis Rev. 11 (1992) 377-388
    • (1992) Cancer Metastasis Rev. , vol.11 , pp. 377-388
    • Lafrenie, R.1    Shaughnessy, S.G.2    Orr, F.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.