A divalent cation stabilizes the active conformation of the B. Subtilis RNase P·Pre-tRNA complex: A role for an inner-sphere metal ion in RNase P

Journal of Molecular Biology

Volumn 400, Issue 1, 2010, Pages 38-51

  Hsieh, John ^a,c   Koutmou, Kristin S ^a   Rueda, David ^a,d   Koutmos, Markos ^a   Walter, Nils G ^a   Fierke, Carol A ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c Caldera Pharmaceuticals   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

Author keywords

Conformational change; Metals; RNase P; TrFRET; TRNA processing

Indexed keywords

CALCIUM; DIVALENT CATION; GLYCINE DEHYDROGENASE (DECARBOXYLATING); MAGNESIUM; METAL ION; RIBONUCLEASE P; TRANSFER RNA;

5' UNTRANSLATED REGION; ARTICLE; BACILLUS SUBTILIS; BINDING AFFINITY; CALCIUM BINDING; CATALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME STABILITY; ENZYME SUBSTRATE; FLUORESCENCE RESONANCE ENERGY TRANSFER; NONHUMAN; PRIORITY JOURNAL; RNA PROCESSING;

BACILLUS SUBTILIS;

EID: 77953699478     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.04.050     Document Type: Article

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