The cleavage step of ribonuclease P catalysis is determined by ribozyme- substrate interactions both distal and proximal to the cleavage site

Biochemistry

Volumn 38, Issue 27, 1999, Pages 8612-8620

  Loria, Andrew ^a   Pan, Tao ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEASE P; RIBOZYME;

ARTICLE; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; KINETICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING;

BACILLUS SUBTILIS; BASE PAIR MISMATCH; BASE SEQUENCE; BINDING SITES; CATALYSIS; ENDORIBONUCLEASES; HYDROLYSIS; HYDROXIDES; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; PROTONS; RIBONUCLEASE P; RNA PRECURSORS; RNA, CATALYTIC; RNA, TRANSFER, PHE; SUBSTRATE SPECIFICITY;

EID: 0033529287     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990691f     Document Type: Article

References (43)

1. Pley, H. W., Flaherty, K. M., and McKay, D. B. (1994) Nature 372, 68-74.
2. Scott, W. G., Finch, J. T., and Klug, A. (1995) Cell 81, 991-1002.
3. Wedekind, J. E., and McKay, D. B. (1998) Annu. Rev. Biophys. Biomol. Struct. 27, 475-502.
4. Narlikar, G. J., and Herschlag, D. (1998) Annu. Rev. Biochem. 66, 19-59.
5. Herschlag, D. (1992) Biochemistry 31, 1386-1399.
6. Wang, J.-F., Downs, W. D., and Cech, T. R. (1993) Science 260, 504-508.
7. Strobel, S. A., Ortoleva-Donnelly, L., Ryder, S. P., Cate, J. H., and Moncoeur, E. (1998) Nat. Struct. Biol. 5, 60-65.
8. Altman, S., Kirsebom, L., and Talbot, S. (1993) FASEB J. 7, 7-14.
9. Pace, N. R., and Brown, J. W. (1995) J. Bacteriol. 177, 1919-1928.
10. Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N., and Altman, S. (1983) Cell 35, 849-857.
11. Loria, A., and Pan, T. (1998) Biochemistry 37, 10126-10133.
12. Loria, A., Niranjanakumari, S., Fierke, C. A., and Pan, T. (1998) Biochemistry 37, 15466-15473.
13. Smith, D., and Pace, N. R. (1993) Biochemistry 32, 5273-5281.
14. Steitz, T. A., and Steitz, J. A. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 6498-6502.
15. Loria, A., and Pan, T. (1997) Biochemistry 36, 6317-6235.
16. Pan, T. (1995) Biochemistry 34, 8458-8464.
17. Pan, T., and Jakacka, M. (1996) EMBO J. 15, 2249-2255.
18. Loria, A., and Pan, T. (1996) RNA 2, 551-563.
19. Fang, X.-W., Pan, T., and Sosnick, T. R. (1999) J. Mol. Biol. (submitted for publication).
20. Niranjanakumari, S., Kurz, J. C., and Fierke, C. A. (1998) Nucleic Acids Res. 26, 3090-3096.
21. Fersht, A. (1985) in Enzyme structure and mechanism, pp 98-120, W. H. Freeman and Co., New York.
22. Odell, L., Huang, V., Jakacka, M., and Pan, T. (1998) Nucleic Acids Res. 26, 3717-3723.
23. Kirsebom, L. A., and Svard, S. G. (1994) EMBO J. 13, 4870-4876.
24. LaGrandeur, T. E., Huttenhofer, A., Noller, H. F., and Pace, N. R. (1994) EMBO J. 13, 3945-3952.
25. Beebe, J. A., and Fierke, C. A. (1994) Biochemistry 33, 10294-10304.
26. Crary, S. M., Niranjanakumari, S., and Fierke, C. A. (1998) Biochemistry 37, 9409-9416.
27. Harris, M. E., Nolan, J. M., Malhotra, A., Brown, J. W., and Pace, N. R. (1994) EMBO J. 13, 3953-3963.
28. Pan, T., Loria, A., and Zhong, K. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 12510-12514.
29. Massire, C., Jaeger, L., and Westhof, E. (1998) J. Mol. Biol. 279, 773-793.
30. Sprinzl, M., Horn, C., Brown, M., Ioudovitch, A., and Steinberg, S. (1998) Nucleic Acids Res. 26, 148-153.
31. Quigley, G., and Rich, A. (1976) Science 194, 796-806.
32. phe and General Structural Features of Other tRNAs (Schimmel, P. R., et al., Eds.) pp 83-100 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
33. Svard, S. F., and Kirsebom, L. A. (1992) J. Mol. Biol. 227, 1019-1031.
34. Holm, P. S., and Krupp, G. (1992) Nucleic Acids Res. 20, 421-423.
35. Kirsebom, L. A., and Svard, S. G. (1992) Nucleic Acids Res. 20, 425-432.
36. Pan, T., and Zhong, K. (1994) Biochemistry 33, 14207-14212.
37. Pan, T., Fang, X.-W., and Sosnick, T. R. (1999) J. Mol. Biol. 286, 721-731.
38. Kurz, J. C., Niranjanakumari, S., and Fierke, C. A. (1998) Biochemistry 37, 2393-2400.
39. Warnecke, J. M., Furste, J. R., Hardt, W.-D., Erdmann, V. A., and Hartmann, R. K. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 8924-8928.
40. Niranjanakumari, S., Stams, T., Crary, S. M., Christianson, D. W., and Fierke, C. A. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 15212-15217.
41. Kahle, D., Wehmeyer, U., and Krupp, G. (1990) EMBO J. 9, 1929-1937.
42. Gaur, R. K., Hanne, A., Conrad, F., Kahle, D., and Krupp, G. (1996) RNA 2, 674-681.
43. Golden, B. L., Gooding, A. R., Podell, E. R., and Cech, T. R. (1998) Science 282, 259-264.