Diffusely bound MG2+ ions slightly reorient stems I and II of the hammerhead ribozyme to increase the probability of formation of the catalytic core

Biochemistry

Volumn 42, Issue 33, 2003, Pages 9924-9936

  Rueda, David ^a   Wick, Katrin ^a   Elizabeth McDowell, S ^a   Walter, Nils G ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COMPLEXATION; DATA ACQUISITION; DISSOCIATION; ENERGY TRANSFER; ENZYMES; FLUORESCENCE; IONS; PH EFFECTS;

RIBOZYMES;

RNA;

MAGNESIUM ION; RIBOZYME; MAGNESIUM; RNA;

ARTICLE; DISSOCIATION CONSTANT; ENERGY TRANSFER; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME STRUCTURE; EQUILIBRIUM CONSTANT; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS; TEMPERATURE DEPENDENCE; BASE PAIRING; BINDING SITE; CATALYSIS; CHEMISTRY; CONFORMATION; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION;

BASE PAIRING; BASE SEQUENCE; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; KINETICS; MAGNESIUM; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; RNA; RNA, CATALYTIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0041972623     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0347757     Document Type: Article

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