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Volumn 16, Issue 7, 2010, Pages 891-906

Regenerative Stromal Cell Therapy in Allogeneic Hematopoietic Stem Cell Transplantation: Current Impact and Future Directions

Author keywords

Graft versus host disease; Hematopoietic stem cell transplantation; Immunomodulation; Mesenchymal stem cell; Microenvironment; Multipotent adult progenitor cell; Rgenerative stromal cell therapy

Indexed keywords

CHEMOKINE; CYTOKINE; IMMUNOMODULATING AGENT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; STEROID; TOLL LIKE RECEPTOR;

EID: 77953618997     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2009.12.005     Document Type: Review
Times cited : (34)

References (162)
  • 1
    • 32544453971 scopus 로고    scopus 로고
    • Shared biology of GVHD and GVT effects: potential methods of separation
    • Fowler D.H. Shared biology of GVHD and GVT effects: potential methods of separation. Crit Rev Oncol Hematol 2006, 57:225-244.
    • (2006) Crit Rev Oncol Hematol , vol.57 , pp. 225-244
    • Fowler, D.H.1
  • 2
    • 44149120553 scopus 로고    scopus 로고
    • Impact of graft-versus-host disease on survival
    • Pasquini M.C. Impact of graft-versus-host disease on survival. Best Pract Res Clin Haematol 2008, 21:193-204.
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 193-204
    • Pasquini, M.C.1
  • 3
    • 0036048349 scopus 로고    scopus 로고
    • Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems
    • MacMillan M.L., Weisdorf D.J., Wagner J.E., et al. Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems. Biol Blood Marrow Transplant 2002, 8:387-394.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 387-394
    • MacMillan, M.L.1    Weisdorf, D.J.2    Wagner, J.E.3
  • 4
    • 62849091765 scopus 로고    scopus 로고
    • Bone marrow transplantation: new approaches to immunosuppression and management of acute graft-versus-host disease
    • Auletta J.J., Cooke K.R. Bone marrow transplantation: new approaches to immunosuppression and management of acute graft-versus-host disease. Curr Opin Pediatr 2009, 21:30-38.
    • (2009) Curr Opin Pediatr , vol.21 , pp. 30-38
    • Auletta, J.J.1    Cooke, K.R.2
  • 5
    • 34247573902 scopus 로고    scopus 로고
    • Graft-versus-host disease
    • Shlomchik W.D. Graft-versus-host disease. Nat Rev Immunol 2007, 7:340-352.
    • (2007) Nat Rev Immunol , vol.7 , pp. 340-352
    • Shlomchik, W.D.1
  • 6
    • 40049109392 scopus 로고    scopus 로고
    • Biological advances in acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    • Duran-Struuck R., Reddy P. Biological advances in acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Transplantation 2008, 85:303-308.
    • (2008) Transplantation , vol.85 , pp. 303-308
    • Duran-Struuck, R.1    Reddy, P.2
  • 7
    • 44049086872 scopus 로고    scopus 로고
    • GVHD pathophysiology: is acute different from chronic?
    • Toubai T., Sun Y., Reddy P. GVHD pathophysiology: is acute different from chronic?. Best Pract Res Clin Haematol 2008, 21:101-117.
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 101-117
    • Toubai, T.1    Sun, Y.2    Reddy, P.3
  • 8
    • 44249112383 scopus 로고    scopus 로고
    • Vascular endothelium and graft-versus-host disease
    • Biedermann B.C. Vascular endothelium and graft-versus-host disease. Best Pract Res Clin Haematol 2008, 21:129-138.
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 129-138
    • Biedermann, B.C.1
  • 10
    • 7944230365 scopus 로고    scopus 로고
    • Acute lung injury after allogeneic stem cell transplantation: is the lung a target of acute graft-versus-host disease?
    • Cooke K.R., Yanik G. Acute lung injury after allogeneic stem cell transplantation: is the lung a target of acute graft-versus-host disease?. Bone Marrow Transplant 2004, 34:753-765.
    • (2004) Bone Marrow Transplant , vol.34 , pp. 753-765
    • Cooke, K.R.1    Yanik, G.2
  • 11
    • 11144311241 scopus 로고    scopus 로고
    • Counting the cost: markers of endothelial damage in hematopoietic stem cell transplantation
    • Woywodt A., Haubitz M., Buchholz S., Hertenstein B. Counting the cost: markers of endothelial damage in hematopoietic stem cell transplantation. Bone Marrow Transplant 2004, 34:1015-1023.
    • (2004) Bone Marrow Transplant , vol.34 , pp. 1015-1023
    • Woywodt, A.1    Haubitz, M.2    Buchholz, S.3    Hertenstein, B.4
  • 12
    • 47149107045 scopus 로고    scopus 로고
    • Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen
    • Bolinger B., Krebs P., Tian Y., et al. Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen. Blood 2008, 111:4588-4595.
    • (2008) Blood , vol.111 , pp. 4588-4595
    • Bolinger, B.1    Krebs, P.2    Tian, Y.3
  • 14
    • 44249108602 scopus 로고    scopus 로고
    • Prophylaxis of acute GVHD: manipulate the graft or the environment?
    • Barrett A.J., Le Blanc K. Prophylaxis of acute GVHD: manipulate the graft or the environment?. Best Pract Res Clin Haematol 2008, 21:165-176.
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 165-176
    • Barrett, A.J.1    Le Blanc, K.2
  • 15
    • 38849116977 scopus 로고    scopus 로고
    • Acute graft-versus-host disease in children
    • Jacobsohn D.A. Acute graft-versus-host disease in children. Bone Marrow Transplant 2008, 41:215-221.
    • (2008) Bone Marrow Transplant , vol.41 , pp. 215-221
    • Jacobsohn, D.A.1
  • 16
    • 44249120602 scopus 로고    scopus 로고
    • Current and novel therapies in acute GVHD
    • Ho V.T., Cutler C. Current and novel therapies in acute GVHD. Best Pract Res Clin Haematol 2008, 21:223-237.
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 223-237
    • Ho, V.T.1    Cutler, C.2
  • 17
    • 34548062133 scopus 로고    scopus 로고
    • Long-term follow-up of patients treated with daclizumab for steroid-refractory acute graft-vs-host disease
    • Perales M.A., Ishill N., Lomazow W.A., et al. Long-term follow-up of patients treated with daclizumab for steroid-refractory acute graft-vs-host disease. Bone Marrow Transplant 2007, 40:481-486.
    • (2007) Bone Marrow Transplant , vol.40 , pp. 481-486
    • Perales, M.A.1    Ishill, N.2    Lomazow, W.A.3
  • 18
    • 4444304402 scopus 로고    scopus 로고
    • Effect of up-front daclizumab when combined with steroids for the treatment of acute graft-versus-host disease: results of a randomized trial
    • Lee S.J., Zahrieh D., Agura E., et al. Effect of up-front daclizumab when combined with steroids for the treatment of acute graft-versus-host disease: results of a randomized trial. Blood 2004, 104:1559-1564.
    • (2004) Blood , vol.104 , pp. 1559-1564
    • Lee, S.J.1    Zahrieh, D.2    Agura, E.3
  • 19
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Jiang Y., Jahagirdar B.N., Reinhardt R.L., et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002, 418:41-49.
    • (2002) Nature , vol.418 , pp. 41-49
    • Jiang, Y.1    Jahagirdar, B.N.2    Reinhardt, R.L.3
  • 20
    • 0031861531 scopus 로고    scopus 로고
    • Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells
    • Majumdar M.K., Thiede M.A., Mosca J.D., Moorman M., Gerson S.L. Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells. J Cell Physiol 1998, 176:57-66.
    • (1998) J Cell Physiol , vol.176 , pp. 57-66
    • Majumdar, M.K.1    Thiede, M.A.2    Mosca, J.D.3    Moorman, M.4    Gerson, S.L.5
  • 21
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
    • Dominici M., Le Blanc K., Mueller I., et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006, 8:315-317.
    • (2006) Cytotherapy , vol.8 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3
  • 22
    • 33750559121 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease
    • Yanez R., Lamana M.L., Garcia-Castro J., Colmenero I., Ramirez M., Bueren J.A. Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease. Stem Cells 2006, 24:2582-2591.
    • (2006) Stem Cells , vol.24 , pp. 2582-2591
    • Yanez, R.1    Lamana, M.L.2    Garcia-Castro, J.3    Colmenero, I.4    Ramirez, M.5    Bueren, J.A.6
  • 23
    • 3543003475 scopus 로고    scopus 로고
    • Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood
    • Bieback K., Kern S., Kluter H., Eichler H. Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood. Stem Cells 2004, 22:625-634.
    • (2004) Stem Cells , vol.22 , pp. 625-634
    • Bieback, K.1    Kern, S.2    Kluter, H.3    Eichler, H.4
  • 24
    • 36049011643 scopus 로고    scopus 로고
    • Human-placenta-derived mesenchymal stem cells inhibit proliferation and function of allogeneic immune cells
    • Li C., Zhang W., Jiang X., Mao N. Human-placenta-derived mesenchymal stem cells inhibit proliferation and function of allogeneic immune cells. Cell Tissue Res 2007, 330:437-446.
    • (2007) Cell Tissue Res , vol.330 , pp. 437-446
    • Li, C.1    Zhang, W.2    Jiang, X.3    Mao, N.4
  • 25
    • 34848863384 scopus 로고    scopus 로고
    • Adult mesenchymal stem cells for tissue engineering versus regenerative medicine
    • Caplan A.I. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. J Cell Physiol 2007, 213:341-347.
    • (2007) J Cell Physiol , vol.213 , pp. 341-347
    • Caplan, A.I.1
  • 26
    • 0031012465 scopus 로고    scopus 로고
    • Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation
    • Bruder S.P., Jaiswal N., Haynesworth S.E. Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation. J Cell Biochem 1997, 64:278-294.
    • (1997) J Cell Biochem , vol.64 , pp. 278-294
    • Bruder, S.P.1    Jaiswal, N.2    Haynesworth, S.E.3
  • 27
    • 0033824164 scopus 로고    scopus 로고
    • Mesenchymal stem cells: biology and potential clinical uses
    • Deans R.J., Moseley A.B. Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol 2000, 28:875-884.
    • (2000) Exp Hematol , vol.28 , pp. 875-884
    • Deans, R.J.1    Moseley, A.B.2
  • 28
    • 0032748173 scopus 로고    scopus 로고
    • Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate
    • Digirolamo C.M., Stokes D., Colter D., Phinney D.G., Class R., Prockop D.J. Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. Br J Haematol 1999, 107:275-281.
    • (1999) Br J Haematol , vol.107 , pp. 275-281
    • Digirolamo, C.M.1    Stokes, D.2    Colter, D.3    Phinney, D.G.4    Class, R.5    Prockop, D.J.6
  • 29
    • 0032768790 scopus 로고    scopus 로고
    • Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells
    • Conget P.A., Minguell J.J. Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. J Cell Physiol 1999, 181:67-73.
    • (1999) J Cell Physiol , vol.181 , pp. 67-73
    • Conget, P.A.1    Minguell, J.J.2
  • 30
    • 0028881201 scopus 로고
    • Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use
    • Lazarus H.M., Haynesworth S.E., Gerson S.L., Rosenthal N.S., Caplan A.I. Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. Bone Marrow Transplant 1995, 16:557-564.
    • (1995) Bone Marrow Transplant , vol.16 , pp. 557-564
    • Lazarus, H.M.1    Haynesworth, S.E.2    Gerson, S.L.3    Rosenthal, N.S.4    Caplan, A.I.5
  • 31
    • 33744913533 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease
    • Ringden O., Uzunel M., Rasmusson I., et al. Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation 2006, 81:1390-1397.
    • (2006) Transplantation , vol.81 , pp. 1390-1397
    • Ringden, O.1    Uzunel, M.2    Rasmusson, I.3
  • 32
    • 67349204472 scopus 로고    scopus 로고
    • Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigms
    • Prockop D.J. Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigms. Mol Ther 2009, 17:939-946.
    • (2009) Mol Ther , vol.17 , pp. 939-946
    • Prockop, D.J.1
  • 33
    • 0036322544 scopus 로고    scopus 로고
    • Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain
    • Jiang Y., Vaessen B., Lenvik T., Blackstad M., Reyes M., Verfaillie C.M. Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain. Exp Hematol 2002, 30:896-904.
    • (2002) Exp Hematol , vol.30 , pp. 896-904
    • Jiang, Y.1    Vaessen, B.2    Lenvik, T.3    Blackstad, M.4    Reyes, M.5    Verfaillie, C.M.6
  • 35
    • 36749000970 scopus 로고    scopus 로고
    • Clinical scale expansion of human pluripotent stem cells
    • Abstract 1060
    • Perry R., Miller D., Deans R. Clinical scale expansion of human pluripotent stem cells. Blood ASH Annu Meet Abstr 2005, 106. Abstract 1060.
    • (2005) Blood ASH Annu Meet Abstr , vol.106
    • Perry, R.1    Miller, D.2    Deans, R.3
  • 36
    • 33846653546 scopus 로고    scopus 로고
    • Development of adult pluripotent stem cell therapies for ischemic injury and disease
    • Mays R.W., van't Hof W., Ting A.E., Perry R., Deans R. Development of adult pluripotent stem cell therapies for ischemic injury and disease. Expert Opin Biol Ther 2007, 7:173-184.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 173-184
    • Mays, R.W.1    van't Hof, W.2    Ting, A.E.3    Perry, R.4    Deans, R.5
  • 38
    • 22344451682 scopus 로고    scopus 로고
    • Multipotent adult progenitor cell and stem cell plasticity
    • Jahagirdar B.N., Verfaillie C.M. Multipotent adult progenitor cell and stem cell plasticity. Stem Cell Rev 2005, 1:53-59.
    • (2005) Stem Cell Rev , vol.1 , pp. 53-59
    • Jahagirdar, B.N.1    Verfaillie, C.M.2
  • 39
    • 0035525779 scopus 로고    scopus 로고
    • Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells
    • Reyes M., Lund T., Lenvik T., Aguiar D., Koodie L., Verfaillie C.M. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 2001, 98:2615-2625.
    • (2001) Blood , vol.98 , pp. 2615-2625
    • Reyes, M.1    Lund, T.2    Lenvik, T.3    Aguiar, D.4    Koodie, L.5    Verfaillie, C.M.6
  • 40
    • 33746424373 scopus 로고    scopus 로고
    • Mesenchymal stem cells as trophic mediators
    • Caplan A.I., Dennis J.E. Mesenchymal stem cells as trophic mediators. J Cell Biochem 2006, 98:1076-1084.
    • (2006) J Cell Biochem , vol.98 , pp. 1076-1084
    • Caplan, A.I.1    Dennis, J.E.2
  • 41
    • 0034489772 scopus 로고    scopus 로고
    • Human marrow-derived mesenchymal stem cells (MSCs) express hematopoietic cytokines and support long-term hematopoiesis when differentiated toward stromal and osteogenic lineages
    • Majumdar M.K., Thiede M.A., Haynesworth S.E., Bruder S.P., Gerson S.L. Human marrow-derived mesenchymal stem cells (MSCs) express hematopoietic cytokines and support long-term hematopoiesis when differentiated toward stromal and osteogenic lineages. J Hematother Stem Cell Res 2000, 9:841-848.
    • (2000) J Hematother Stem Cell Res , vol.9 , pp. 841-848
    • Majumdar, M.K.1    Thiede, M.A.2    Haynesworth, S.E.3    Bruder, S.P.4    Gerson, S.L.5
  • 42
    • 0029867151 scopus 로고    scopus 로고
    • Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alpha
    • Haynesworth S.E., Baber M.A., Caplan A.I. Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alpha. J Cell Physiol 1996, 166:585-592.
    • (1996) J Cell Physiol , vol.166 , pp. 585-592
    • Haynesworth, S.E.1    Baber, M.A.2    Caplan, A.I.3
  • 43
    • 0041327804 scopus 로고    scopus 로고
    • Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy
    • Askari A.T., Unzek S., Popovic Z.B., et al. Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet 2003, 362:697-703.
    • (2003) Lancet , vol.362 , pp. 697-703
    • Askari, A.T.1    Unzek, S.2    Popovic, Z.B.3
  • 44
    • 45149091594 scopus 로고    scopus 로고
    • Culturing of human mesenchymal stem cells as three-dimensional aggregates induces functional expression of CXCR4 that regulates adhesion to endothelial cells
    • Potapova I.A., Brink P.R., Cohen I.S., Doronin S.V. Culturing of human mesenchymal stem cells as three-dimensional aggregates induces functional expression of CXCR4 that regulates adhesion to endothelial cells. J Biol Chem 2008, 283:13100-13107.
    • (2008) J Biol Chem , vol.283 , pp. 13100-13107
    • Potapova, I.A.1    Brink, P.R.2    Cohen, I.S.3    Doronin, S.V.4
  • 45
    • 0036458679 scopus 로고    scopus 로고
    • Expansion of LTC-ICs and maintenance of p21 and BCL-2 expression in cord blood CD34(+)/CD38(-) early progenitors cultured over human MSCs as a feeder layer
    • Kadereit S., Deeds L.S., Haynesworth S.E., et al. Expansion of LTC-ICs and maintenance of p21 and BCL-2 expression in cord blood CD34(+)/CD38(-) early progenitors cultured over human MSCs as a feeder layer. Stem Cells 2002, 20:573-582.
    • (2002) Stem Cells , vol.20 , pp. 573-582
    • Kadereit, S.1    Deeds, L.S.2    Haynesworth, S.E.3
  • 46
    • 18444374992 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice
    • Noort W.A., Kruisselbrink A.B., in't Anker P.S., et al. Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol 2002, 30:870-878.
    • (2002) Exp Hematol , vol.30 , pp. 870-878
    • Noort, W.A.1    Kruisselbrink, A.B.2    in't Anker, P.S.3
  • 47
    • 0037562968 scopus 로고    scopus 로고
    • Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice
    • Angelopoulou M., Novelli E., Grove J.E., et al. Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice. Exp Hematol 2003, 31:413-420.
    • (2003) Exp Hematol , vol.31 , pp. 413-420
    • Angelopoulou, M.1    Novelli, E.2    Grove, J.E.3
  • 48
    • 1842483153 scopus 로고    scopus 로고
    • Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation
    • Maitra B., Szekely E., Gjini K., et al. Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation. Bone Marrow Transplant 2004, 33:597-604.
    • (2004) Bone Marrow Transplant , vol.33 , pp. 597-604
    • Maitra, B.1    Szekely, E.2    Gjini, K.3
  • 49
    • 34548555990 scopus 로고    scopus 로고
    • Direct delivery of syngeneic and allogeneic large-scale expanded multipotent adult progenitor cells improves cardiac function after myocardial infarct
    • Van't Hof W., Mal N., Huang Y., et al. Direct delivery of syngeneic and allogeneic large-scale expanded multipotent adult progenitor cells improves cardiac function after myocardial infarct. Cytotherapy 2007, 9:477-487.
    • (2007) Cytotherapy , vol.9 , pp. 477-487
    • Van't Hof, W.1    Mal, N.2    Huang, Y.3
  • 50
    • 33846437812 scopus 로고    scopus 로고
    • Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells
    • Serafini M., Dylla S.J., Oki M., et al. Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells. J Exp Med 2007, 204:129-139.
    • (2007) J Exp Med , vol.204 , pp. 129-139
    • Serafini, M.1    Dylla, S.J.2    Oki, M.3
  • 51
    • 56049104232 scopus 로고    scopus 로고
    • Pre-clinical safety testing supporting clinical use of allogeneic multipotent adult progenitor cells
    • Kovacsovics-Bankowski M., Mauch K., Raber A., et al. Pre-clinical safety testing supporting clinical use of allogeneic multipotent adult progenitor cells. Cytotherapy 2008, 10:730-742.
    • (2008) Cytotherapy , vol.10 , pp. 730-742
    • Kovacsovics-Bankowski, M.1    Mauch, K.2    Raber, A.3
  • 52
    • 33646548959 scopus 로고    scopus 로고
    • Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells
    • Tolar J., O'Shaughnessy M.J., Panoskaltsis-Mortari A., et al. Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells. Blood 2006, 107:4182-4188.
    • (2006) Blood , vol.107 , pp. 4182-4188
    • Tolar, J.1    O'Shaughnessy, M.J.2    Panoskaltsis-Mortari, A.3
  • 53
    • 20244389227 scopus 로고    scopus 로고
    • Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients
    • Lazarus H.M., Koc O.N., Devine S.M., et al. Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients. Biol Blood Marrow Transplant 2005, 11:389-398.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 389-398
    • Lazarus, H.M.1    Koc, O.N.2    Devine, S.M.3
  • 54
    • 34447639255 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells
    • Le Blanc K., Samuelsson H., Gustafsson B., et al. Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells. Leukemia 2007, 21:1733-1738.
    • (2007) Leukemia , vol.21 , pp. 1733-1738
    • Le Blanc, K.1    Samuelsson, H.2    Gustafsson, B.3
  • 55
    • 0033977382 scopus 로고    scopus 로고
    • Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy
    • Koc O.N., Gerson S.L., Cooper B.W., et al. Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J Clin Oncol 2000, 18:307-316.
    • (2000) J Clin Oncol , vol.18 , pp. 307-316
    • Koc, O.N.1    Gerson, S.L.2    Cooper, B.W.3
  • 56
    • 34948892668 scopus 로고    scopus 로고
    • Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation
    • Ball L.M., Bernardo M.E., Roelofs H., et al. Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation. Blood 2007, 110:2764-2767.
    • (2007) Blood , vol.110 , pp. 2764-2767
    • Ball, L.M.1    Bernardo, M.E.2    Roelofs, H.3
  • 57
    • 33745215431 scopus 로고    scopus 로고
    • Donor multipotent mesenchymal stromal cells may engraft in pediatric patients given either cord blood or bone marrow transplantation
    • Pozzi S., Lisini D., Podesta M., et al. Donor multipotent mesenchymal stromal cells may engraft in pediatric patients given either cord blood or bone marrow transplantation. Exp Hematol 2006, 34:934-942.
    • (2006) Exp Hematol , vol.34 , pp. 934-942
    • Pozzi, S.1    Lisini, D.2    Podesta, M.3
  • 58
    • 63949085855 scopus 로고    scopus 로고
    • Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial
    • Macmillan M.L., Blazar B.R., DeFor T.E., Wagner J.E. Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial. Bone Marrow Transplant 2009, 43:447-454.
    • (2009) Bone Marrow Transplant , vol.43 , pp. 447-454
    • Macmillan, M.L.1    Blazar, B.R.2    DeFor, T.E.3    Wagner, J.E.4
  • 59
    • 40749112327 scopus 로고    scopus 로고
    • The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study
    • Ning H., Yang F., Jiang M., et al. The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study. Leukemia 2008, 22:593-599.
    • (2008) Leukemia , vol.22 , pp. 593-599
    • Ning, H.1    Yang, F.2    Jiang, M.3
  • 60
    • 0032925228 scopus 로고    scopus 로고
    • Adhesion molecules involved in the interactions between early T cells and mesenchymal bone marrow stromal cells
    • Barda-Saad M., Rozenszajn L.A., Ashush H., Shav-Tal Y., Ben Nun A., Zipori D. Adhesion molecules involved in the interactions between early T cells and mesenchymal bone marrow stromal cells. Exp Hematol 1999, 27:834-844.
    • (1999) Exp Hematol , vol.27 , pp. 834-844
    • Barda-Saad, M.1    Rozenszajn, L.A.2    Ashush, H.3    Shav-Tal, Y.4    Ben Nun, A.5    Zipori, D.6
  • 61
    • 67650607997 scopus 로고    scopus 로고
    • Acute graft-versus-host disease transiently impairs thymic output in young patients after allogeneic hematopoietic stem cell transplantation
    • Clave E., Busson M., Douay C., et al. Acute graft-versus-host disease transiently impairs thymic output in young patients after allogeneic hematopoietic stem cell transplantation. Blood 2009, 113:6477-6484.
    • (2009) Blood , vol.113 , pp. 6477-6484
    • Clave, E.1    Busson, M.2    Douay, C.3
  • 62
    • 0036106054 scopus 로고    scopus 로고
    • Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells
    • Schwartz R.E., Reyes M., Koodie L., et al. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin Invest 2002, 109:1291-1302.
    • (2002) J Clin Invest , vol.109 , pp. 1291-1302
    • Schwartz, R.E.1    Reyes, M.2    Koodie, L.3
  • 63
    • 45249100402 scopus 로고    scopus 로고
    • Co-infusion of donor bone marrow with host mesenchymal stem cells treats GVHD and promotes vascularized skin allograft survival in rats
    • Aksu A.E., Horibe E., Sacks J., et al. Co-infusion of donor bone marrow with host mesenchymal stem cells treats GVHD and promotes vascularized skin allograft survival in rats. Clin Immunol 2008, 127:348-358.
    • (2008) Clin Immunol , vol.127 , pp. 348-358
    • Aksu, A.E.1    Horibe, E.2    Sacks, J.3
  • 64
    • 35449007194 scopus 로고    scopus 로고
    • Tissue repair using allogeneic mesenchymal stem cells for hemorrhagic cystitis, pneumomediastinum and perforated colon
    • Ringden O., Uzunel M., Sundberg B., et al. Tissue repair using allogeneic mesenchymal stem cells for hemorrhagic cystitis, pneumomediastinum and perforated colon. Leukemia 2007, 21:2271-2276.
    • (2007) Leukemia , vol.21 , pp. 2271-2276
    • Ringden, O.1    Uzunel, M.2    Sundberg, B.3
  • 65
    • 45149085724 scopus 로고    scopus 로고
    • Third party mesenchymal stromal cell infusions fail to induce tissue repair despite successful control of severe grade IV acute graft-versus-host disease in a child with juvenile myelo-monocytic leukemia
    • Ball L., Bredius R., Lankester A., et al. Third party mesenchymal stromal cell infusions fail to induce tissue repair despite successful control of severe grade IV acute graft-versus-host disease in a child with juvenile myelo-monocytic leukemia. Leukemia 2008, 22:1256-1257.
    • (2008) Leukemia , vol.22 , pp. 1256-1257
    • Ball, L.1    Bredius, R.2    Lankester, A.3
  • 66
    • 34147139536 scopus 로고    scopus 로고
    • Clinical trials with adult stem/progenitor cells for tissue repair: let's not overlook some essential precautions
    • Prockop D.J., Olson S.D. Clinical trials with adult stem/progenitor cells for tissue repair: let's not overlook some essential precautions. Blood 2007, 109:3147-3151.
    • (2007) Blood , vol.109 , pp. 3147-3151
    • Prockop, D.J.1    Olson, S.D.2
  • 67
    • 33745231146 scopus 로고    scopus 로고
    • Immune modulation by mesenchymal stem cells
    • Rasmusson I. Immune modulation by mesenchymal stem cells. Exp Cell Res 2006, 312:2169-2179.
    • (2006) Exp Cell Res , vol.312 , pp. 2169-2179
    • Rasmusson, I.1
  • 68
    • 35448996504 scopus 로고    scopus 로고
    • Immunomodulation by mesenchymal stem cells and clinical experience
    • Le Blanc K., Ringden O. Immunomodulation by mesenchymal stem cells and clinical experience. J Intern Med 2007, 262:509-525.
    • (2007) J Intern Med , vol.262 , pp. 509-525
    • Le Blanc, K.1    Ringden, O.2
  • 69
    • 38649103172 scopus 로고    scopus 로고
    • How do mesenchymal stromal cells suppress T cells?
    • Keating A. How do mesenchymal stromal cells suppress T cells?. Cell Stem Cell 2008, 2:106-108.
    • (2008) Cell Stem Cell , vol.2 , pp. 106-108
    • Keating, A.1
  • 70
    • 0141707822 scopus 로고    scopus 로고
    • Role of CXCR3-induced donor T-cell migration in acute GVHD
    • Duffner U., Lu B., Hildebrandt G.C., et al. Role of CXCR3-induced donor T-cell migration in acute GVHD. Exp Hematol 2003, 31:897-902.
    • (2003) Exp Hematol , vol.31 , pp. 897-902
    • Duffner, U.1    Lu, B.2    Hildebrandt, G.C.3
  • 71
    • 0036281797 scopus 로고    scopus 로고
    • Acute graft-versus-host disease does not require alloantigen expression on host epithelium
    • Teshima T., Ordemann R., Reddy P., et al. Acute graft-versus-host disease does not require alloantigen expression on host epithelium. Nat Med 2002, 8:575-581.
    • (2002) Nat Med , vol.8 , pp. 575-581
    • Teshima, T.1    Ordemann, R.2    Reddy, P.3
  • 72
    • 0032903573 scopus 로고    scopus 로고
    • Distinct patterns and kinetics of chemokine production regulate dendritic cell function
    • Sallusto F., Palermo B., Lenig D., et al. Distinct patterns and kinetics of chemokine production regulate dendritic cell function. Eur J Immunol 1999, 29:1617-1625.
    • (1999) Eur J Immunol , vol.29 , pp. 1617-1625
    • Sallusto, F.1    Palermo, B.2    Lenig, D.3
  • 73
    • 33746898242 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cells
    • Nauta A.J., Kruisselbrink A.B., Lurvink E., Willemze R., Fibbe W.E. Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cells. J Immunol 2006, 177:2080-2087.
    • (2006) J Immunol , vol.177 , pp. 2080-2087
    • Nauta, A.J.1    Kruisselbrink, A.B.2    Lurvink, E.3    Willemze, R.4    Fibbe, W.E.5
  • 74
    • 18544371666 scopus 로고    scopus 로고
    • Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells
    • Jiang X.X., Zhang Y., Liu B., et al. Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Blood 2005, 105:4120-4126.
    • (2005) Blood , vol.105 , pp. 4120-4126
    • Jiang, X.X.1    Zhang, Y.2    Liu, B.3
  • 75
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S., Pittenger M.F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005, 105:1815-1822.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 76
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness
    • Beyth S., Borovsky Z., Mevorach D., et al. Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood 2005, 105:2214-2219.
    • (2005) Blood , vol.105 , pp. 2214-2219
    • Beyth, S.1    Borovsky, Z.2    Mevorach, D.3
  • 77
    • 55049140192 scopus 로고    scopus 로고
    • Mesenchymal stem cells alter migratory property of T and dendritic cells to delay the development of murine lethal acute graft-versus-host disease
    • Li H., Guo Z., Jiang X., Zhu H., Li X., Mao N. Mesenchymal stem cells alter migratory property of T and dendritic cells to delay the development of murine lethal acute graft-versus-host disease. Stem Cells 2008, 26:2531-2541.
    • (2008) Stem Cells , vol.26 , pp. 2531-2541
    • Li, H.1    Guo, Z.2    Jiang, X.3    Zhu, H.4    Li, X.5    Mao, N.6
  • 78
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
    • Spaggiari G.M., Capobianco A., Becchetti S., Mingari M.C., Moretta L. Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. Blood 2006, 107:1484-1490.
    • (2006) Blood , vol.107 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3    Mingari, M.C.4    Moretta, L.5
  • 80
    • 11844268647 scopus 로고    scopus 로고
    • The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions
    • Gerosa F., Gobbi A., Zorzi P., et al. The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions. J Immunol 2005, 174:727-734.
    • (2005) J Immunol , vol.174 , pp. 727-734
    • Gerosa, F.1    Gobbi, A.2    Zorzi, P.3
  • 81
    • 26844581032 scopus 로고    scopus 로고
    • Natural-killer cells and dendritic cells: " l'union fait la force."
    • Walzer T., Dalod M., Robbins S.H., Zitvogel L., Vivier E. Natural-killer cells and dendritic cells: " l'union fait la force." Blood 2005, 106:2252-2258.
    • (2005) Blood , vol.106 , pp. 2252-2258
    • Walzer, T.1    Dalod, M.2    Robbins, S.H.3    Zitvogel, L.4    Vivier, E.5
  • 82
    • 59349085292 scopus 로고    scopus 로고
    • Clinical scale expanded adult pluripotent stem cells prevent graft-versus-host disease
    • Kovacsovics-Bankowski M., Streeter P.R., Mauch K.A., et al. Clinical scale expanded adult pluripotent stem cells prevent graft-versus-host disease. Cell Immunol 2009, 255:55-60.
    • (2009) Cell Immunol , vol.255 , pp. 55-60
    • Kovacsovics-Bankowski, M.1    Streeter, P.R.2    Mauch, K.A.3
  • 83
    • 70149119503 scopus 로고    scopus 로고
    • Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming
    • Highfill S.L., Kelly R.M., O'Shaughnessy M.J., et al. Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming. Blood 2009, 114:693-701.
    • (2009) Blood , vol.114 , pp. 693-701
    • Highfill, S.L.1    Kelly, R.M.2    O'Shaughnessy, M.J.3
  • 84
    • 0141484485 scopus 로고    scopus 로고
    • HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells
    • Le Blanc K., Tammik C., Rosendahl K., Zetterberg E., Ringden O. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 2003, 31:890-896.
    • (2003) Exp Hematol , vol.31 , pp. 890-896
    • Le Blanc, K.1    Tammik, C.2    Rosendahl, K.3    Zetterberg, E.4    Ringden, O.5
  • 85
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • Krampera M., Glennie S., Dyson J., et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 2003, 101:3722-3729.
    • (2003) Blood , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3
  • 86
    • 56249139741 scopus 로고    scopus 로고
    • Immune properties of human umbilical cord Wharton's jelly-derived cells
    • Weiss M.L., Anderson C., Medicetty S., et al. Immune properties of human umbilical cord Wharton's jelly-derived cells. Stem Cells 2008, 26:2865-2874.
    • (2008) Stem Cells , vol.26 , pp. 2865-2874
    • Weiss, M.L.1    Anderson, C.2    Medicetty, S.3
  • 87
    • 20244381685 scopus 로고    scopus 로고
    • Immunomodulatory effect of human adipose tissue-derived adult stem cells: comparison with bone marrow mesenchymal stem cells
    • Puissant B., Barreau C., Bourin P., et al. Immunomodulatory effect of human adipose tissue-derived adult stem cells: comparison with bone marrow mesenchymal stem cells. Br J Haematol 2005, 129:118-129.
    • (2005) Br J Haematol , vol.129 , pp. 118-129
    • Puissant, B.1    Barreau, C.2    Bourin, P.3
  • 88
    • 36349017810 scopus 로고    scopus 로고
    • A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells
    • Chabannes D., Hill M., Merieau E., et al. A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells. Blood 2007, 110:3691-3694.
    • (2007) Blood , vol.110 , pp. 3691-3694
    • Chabannes, D.1    Hill, M.2    Merieau, E.3
  • 89
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M., Carlo-Stella C., Magni M., et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002, 99:3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3
  • 90
    • 38349053355 scopus 로고    scopus 로고
    • Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells
    • Selmani Z., Naji A., Zidi I., et al. Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells. Stem Cells 2008, 26:212-222.
    • (2008) Stem Cells , vol.26 , pp. 212-222
    • Selmani, Z.1    Naji, A.2    Zidi, I.3
  • 91
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel R., Zibert A., Laryea M., Gobel U., Daubener W., Dilloo D. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 2004, 103:4619-4621.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 92
    • 34347371299 scopus 로고    scopus 로고
    • Identification of IL-10 and TGF-beta transcripts involved in the inhibition of T-lymphocyte proliferation during cell contact with human mesenchymal stem cells
    • Nasef A., Chapel A., Mazurier C., et al. Identification of IL-10 and TGF-beta transcripts involved in the inhibition of T-lymphocyte proliferation during cell contact with human mesenchymal stem cells. Gene Expr 2007, 13:217-226.
    • (2007) Gene Expr , vol.13 , pp. 217-226
    • Nasef, A.1    Chapel, A.2    Mazurier, C.3
  • 93
    • 22144473736 scopus 로고    scopus 로고
    • Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells
    • Groh M.E., Maitra B., Szekely E., Koc O.N. Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells. Exp Hematol 2005, 33:928-934.
    • (2005) Exp Hematol , vol.33 , pp. 928-934
    • Groh, M.E.1    Maitra, B.2    Szekely, E.3    Koc, O.N.4
  • 94
    • 34548739534 scopus 로고    scopus 로고
    • Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction
    • Prevosto C., Zancolli M., Canevali P., Zocchi M.R., Poggi A. Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction. Haematologica 2007, 92:881-888.
    • (2007) Haematologica , vol.92 , pp. 881-888
    • Prevosto, C.1    Zancolli, M.2    Canevali, P.3    Zocchi, M.R.4    Poggi, A.5
  • 95
    • 33744917000 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice
    • Sudres M., Norol F., Trenado A., et al. Bone marrow mesenchymal stem cells suppress lymphocyte proliferation in vitro but fail to prevent graft-versus-host disease in mice. J Immunol 2006, 176:7761-7767.
    • (2006) J Immunol , vol.176 , pp. 7761-7767
    • Sudres, M.1    Norol, F.2    Trenado, A.3
  • 96
    • 40949106952 scopus 로고    scopus 로고
    • Murine bone marrow derived stromal progenitor cells fail to prevent or treat acute graft-versus-host disease
    • Badillo A.T., Peranteau W.H., Heaton T.E., Quinn C., Flake A.W. Murine bone marrow derived stromal progenitor cells fail to prevent or treat acute graft-versus-host disease. Br J Haematol 2008, 141:224-234.
    • (2008) Br J Haematol , vol.141 , pp. 224-234
    • Badillo, A.T.1    Peranteau, W.H.2    Heaton, T.E.3    Quinn, C.4    Flake, A.W.5
  • 97
    • 33746514768 scopus 로고    scopus 로고
    • Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting
    • Nauta A.J., Westerhuis G., Kruisselbrink A.B., Lurvink E.G., Willemze R., Fibbe W.E. Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting. Blood 2006, 108:2114-2120.
    • (2006) Blood , vol.108 , pp. 2114-2120
    • Nauta, A.J.1    Westerhuis, G.2    Kruisselbrink, A.B.3    Lurvink, E.G.4    Willemze, R.5    Fibbe, W.E.6
  • 98
    • 52049101144 scopus 로고    scopus 로고
    • Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation
    • Prigozhina T.B., Khitrin S., Elkin G., Eizik O., Morecki S., Slavin S. Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation. Exp Hematol 2008, 36:1370-1376.
    • (2008) Exp Hematol , vol.36 , pp. 1370-1376
    • Prigozhina, T.B.1    Khitrin, S.2    Elkin, G.3    Eizik, O.4    Morecki, S.5    Slavin, S.6
  • 99
    • 28844483809 scopus 로고    scopus 로고
    • Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice
    • Eliopoulos N., Stagg J., Lejeune L., Pommey S., Galipeau J. Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice. Blood 2005, 106:4057-4065.
    • (2005) Blood , vol.106 , pp. 4057-4065
    • Eliopoulos, N.1    Stagg, J.2    Lejeune, L.3    Pommey, S.4    Galipeau, J.5
  • 100
    • 38549147527 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells decrease acute graft-versus-host disease after allogeneic hematopoietic stem cells transplantation
    • Tian Y., Deng Y.B., Huang Y.J., Wang Y. Bone marrow-derived mesenchymal stem cells decrease acute graft-versus-host disease after allogeneic hematopoietic stem cells transplantation. Immunol Invest 2008, 37:29-42.
    • (2008) Immunol Invest , vol.37 , pp. 29-42
    • Tian, Y.1    Deng, Y.B.2    Huang, Y.J.3    Wang, Y.4
  • 101
    • 38649105374 scopus 로고    scopus 로고
    • Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
    • Ren G., Zhang L., Zhao X., et al. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008, 2:141-150.
    • (2008) Cell Stem Cell , vol.2 , pp. 141-150
    • Ren, G.1    Zhang, L.2    Zhao, X.3
  • 102
    • 49649106257 scopus 로고    scopus 로고
    • IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
    • Polchert D., Sobinsky J., Douglas G., et al. IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease. Eur J Immunol 2008, 38:1745-1755.
    • (2008) Eur J Immunol , vol.38 , pp. 1745-1755
    • Polchert, D.1    Sobinsky, J.2    Douglas, G.3
  • 103
    • 34248213189 scopus 로고    scopus 로고
    • IL-10-transduced bone marrow mesenchymal stem cells can attenuate the severity of acute graft-versus-host disease after experimental allogeneic stem cell transplantation
    • Min C.K., Kim B.G., Park G., Cho B., Oh I.H. IL-10-transduced bone marrow mesenchymal stem cells can attenuate the severity of acute graft-versus-host disease after experimental allogeneic stem cell transplantation. Bone Marrow Transplant 2007, 39:637-645.
    • (2007) Bone Marrow Transplant , vol.39 , pp. 637-645
    • Min, C.K.1    Kim, B.G.2    Park, G.3    Cho, B.4    Oh, I.H.5
  • 104
    • 34548118697 scopus 로고    scopus 로고
    • Mesenchymal stem cells of cord blood origin are effective at preventing but not treating graft-versus-host disease
    • Tisato V., Naresh K., Girdlestone J., Navarrete C., Dazzi F. Mesenchymal stem cells of cord blood origin are effective at preventing but not treating graft-versus-host disease. Leukemia 2007, 21:1992-1999.
    • (2007) Leukemia , vol.21 , pp. 1992-1999
    • Tisato, V.1    Naresh, K.2    Girdlestone, J.3    Navarrete, C.4    Dazzi, F.5
  • 105
    • 73349118783 scopus 로고    scopus 로고
    • Acute graft-versus-host disease; from the bench to the bedside
    • Socie G., Blazar B.R. Acute graft-versus-host disease; from the bench to the bedside. Blood 2009, 114:4327-4336.
    • (2009) Blood , vol.114 , pp. 4327-4336
    • Socie, G.1    Blazar, B.R.2
  • 106
    • 8144229816 scopus 로고    scopus 로고
    • Innate immune response in Th1- and Th2-dominant mouse strains
    • Watanabe H., Numata K., Ito T., Takagi K., Matsukawa A. Innate immune response in Th1- and Th2-dominant mouse strains. Shock 2004, 22:460-466.
    • (2004) Shock , vol.22 , pp. 460-466
    • Watanabe, H.1    Numata, K.2    Ito, T.3    Takagi, K.4    Matsukawa, A.5
  • 107
    • 9444227099 scopus 로고    scopus 로고
    • Cotransplantation of marrow stromal cells may prevent lethal graft-versus-host disease in major histocompatibility complex mismatched murine hematopoietic stem cell transplantation
    • Chung N.G., Jeong D.C., Park S.J., et al. Cotransplantation of marrow stromal cells may prevent lethal graft-versus-host disease in major histocompatibility complex mismatched murine hematopoietic stem cell transplantation. Int J Hematol 2004, 80:370-376.
    • (2004) Int J Hematol , vol.80 , pp. 370-376
    • Chung, N.G.1    Jeong, D.C.2    Park, S.J.3
  • 108
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K., Rasmusson I., Sundberg B., et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004, 363:1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 109
    • 36749056828 scopus 로고    scopus 로고
    • Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantation
    • Muller I., Kordowich S., Holzwarth C., et al. Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantation. Blood Cells Mol Dis 2008, 40:25-32.
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 25-32
    • Muller, I.1    Kordowich, S.2    Holzwarth, C.3
  • 110
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
    • Le Blanc K., Frassoni F., Ball L., et al. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study. Lancet 2008, 371:1579-1586.
    • (2008) Lancet , vol.371 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3
  • 111
    • 67149093649 scopus 로고    scopus 로고
    • Adult human mesenchymal stem cells added to corticosteroid therapy for the treatment of acute graft-versus-host disease
    • Kebriaei P., Isola L., Bahceci E., et al. Adult human mesenchymal stem cells added to corticosteroid therapy for the treatment of acute graft-versus-host disease. Biol Blood Marrow Transplant 2009, 15:804-811.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 804-811
    • Kebriaei, P.1    Isola, L.2    Bahceci, E.3
  • 112
    • 60349129494 scopus 로고    scopus 로고
    • Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium
    • von Bonin M., Stolzel F., Goedecke A., et al. Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium. Bone Marrow Transplant 2009, 43:245-251.
    • (2009) Bone Marrow Transplant , vol.43 , pp. 245-251
    • von Bonin, M.1    Stolzel, F.2    Goedecke, A.3
  • 113
    • 20544474210 scopus 로고    scopus 로고
    • Pathogen recognition with Toll-like receptors
    • Kawai T., Akira S. Pathogen recognition with Toll-like receptors. Curr Opin Immunol 2005, 17:338-344.
    • (2005) Curr Opin Immunol , vol.17 , pp. 338-344
    • Kawai, T.1    Akira, S.2
  • 114
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S., Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004, 4:499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 115
    • 33744978765 scopus 로고    scopus 로고
    • Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment
    • Nagai Y., Garrett K.P., Ohta S., et al. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity 2006, 24:801-812.
    • (2006) Immunity , vol.24 , pp. 801-812
    • Nagai, Y.1    Garrett, K.P.2    Ohta, S.3
  • 116
    • 33744996908 scopus 로고    scopus 로고
    • Outside influence: TLRs direct hematopoietic cell fates
    • Holl T.M., Kelsoe G. Outside influence: TLRs direct hematopoietic cell fates. Immunity 2006, 24:667-669.
    • (2006) Immunity , vol.24 , pp. 667-669
    • Holl, T.M.1    Kelsoe, G.2
  • 117
    • 33846914143 scopus 로고    scopus 로고
    • Toll-like receptors and their ligands control mesenchymal stem cell functions
    • Pevsner-Fischer M., Morad V., Cohen-Sfady M., et al. Toll-like receptors and their ligands control mesenchymal stem cell functions. Blood 2007, 109:1422-1432.
    • (2007) Blood , vol.109 , pp. 1422-1432
    • Pevsner-Fischer, M.1    Morad, V.2    Cohen-Sfady, M.3
  • 118
    • 33845995756 scopus 로고    scopus 로고
    • Role of toll-like receptors on human adipose-derived stromal cells
    • Hwa Cho H., Bae Y.C., Jung J.S. Role of toll-like receptors on human adipose-derived stromal cells. Stem Cells 2006, 24:2744-2752.
    • (2006) Stem Cells , vol.24 , pp. 2744-2752
    • Hwa Cho, H.1    Bae, Y.C.2    Jung, J.S.3
  • 119
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • Takeda K., Akira S. Toll-like receptors in innate immunity. Int Immunol 2005, 17:1-14.
    • (2005) Int Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 120
    • 8144222235 scopus 로고    scopus 로고
    • Increased expression of toll-like receptor-2 and -4 on leukocytes from patients with sepsis
    • Harter L., Mica L., Stocker R., Trentz O., Keel M. Increased expression of toll-like receptor-2 and -4 on leukocytes from patients with sepsis. Shock 2004, 22:403-409.
    • (2004) Shock , vol.22 , pp. 403-409
    • Harter, L.1    Mica, L.2    Stocker, R.3    Trentz, O.4    Keel, M.5
  • 121
    • 2142703865 scopus 로고    scopus 로고
    • Differential expression of Toll-like receptor (TLR)-2 and TLR-4 on monocytes in human sepsis
    • Armstrong L., Medford A.R., Hunter K.J., Uppington K.M., Millar A.B. Differential expression of Toll-like receptor (TLR)-2 and TLR-4 on monocytes in human sepsis. Clin Exp Immunol 2004, 136:312-319.
    • (2004) Clin Exp Immunol , vol.136 , pp. 312-319
    • Armstrong, L.1    Medford, A.R.2    Hunter, K.J.3    Uppington, K.M.4    Millar, A.B.5
  • 122
    • 13544263585 scopus 로고    scopus 로고
    • IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29
    • Siren J., Pirhonen J., Julkunen I., Matikainen S. IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29. J Immunol 2005, 174:1932-1937.
    • (2005) J Immunol , vol.174 , pp. 1932-1937
    • Siren, J.1    Pirhonen, J.2    Julkunen, I.3    Matikainen, S.4
  • 123
    • 22244489703 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha blockade treatment down-modulates the increased systemic and local expression of Toll-like receptor 2 and Toll-like receptor 4 in spondylarthropathy
    • De Rycke L., Vandooren B., Kruithof E., De Keyser F., Veys E.M., Baeten D. Tumor necrosis factor alpha blockade treatment down-modulates the increased systemic and local expression of Toll-like receptor 2 and Toll-like receptor 4 in spondylarthropathy. Arthritis Rheum 2005, 52:2146-2158.
    • (2005) Arthritis Rheum , vol.52 , pp. 2146-2158
    • De Rycke, L.1    Vandooren, B.2    Kruithof, E.3    De Keyser, F.4    Veys, E.M.5    Baeten, D.6
  • 124
    • 0036569028 scopus 로고    scopus 로고
    • Up-regulation of TLR9 gene expression by LPS in mouse macrophages via activation of NF-kappaB, ERK and p38 MAPK signal pathways
    • An H., Xu H., Yu Y., et al. Up-regulation of TLR9 gene expression by LPS in mouse macrophages via activation of NF-kappaB, ERK and p38 MAPK signal pathways. Immunol Lett 2002, 81:165-169.
    • (2002) Immunol Lett , vol.81 , pp. 165-169
    • An, H.1    Xu, H.2    Yu, Y.3
  • 125
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • Hornung V., Rothenfusser S., Britsch S., et al. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 2002, 168:4531-4537.
    • (2002) J Immunol , vol.168 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3
  • 126
    • 35348976806 scopus 로고    scopus 로고
    • Upregulated functional expression of Toll like receptor 4 in mesenchymal stem cells induced by lipopolysaccharide
    • Shi L., Wang J.S., Liu X.M., Hu X.Y., Fang Q. Upregulated functional expression of Toll like receptor 4 in mesenchymal stem cells induced by lipopolysaccharide. Chin Med J (Engl) 2007, 120:1685-1688.
    • (2007) Chin Med J (Engl) , vol.120 , pp. 1685-1688
    • Shi, L.1    Wang, J.S.2    Liu, X.M.3    Hu, X.Y.4    Fang, Q.5
  • 127
    • 0842321777 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B
    • Asehnoune K., Strassheim D., Mitra S., Kim J.Y., Abraham E. Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B. J Immunol 2004, 172:2522-2529.
    • (2004) J Immunol , vol.172 , pp. 2522-2529
    • Asehnoune, K.1    Strassheim, D.2    Mitra, S.3    Kim, J.Y.4    Abraham, E.5
  • 128
    • 1242329363 scopus 로고    scopus 로고
    • Mode of action of endotoxin: role of free radicals and antioxidants
    • Bhattacharyya J., Biswas S., Datta A.G. Mode of action of endotoxin: role of free radicals and antioxidants. Curr Med Chem 2004, 11:359-368.
    • (2004) Curr Med Chem , vol.11 , pp. 359-368
    • Bhattacharyya, J.1    Biswas, S.2    Datta, A.G.3
  • 129
    • 23944437926 scopus 로고    scopus 로고
    • Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression
    • Chauveau C., Remy S., Royer P.J., et al. Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression. Blood 2005, 106:1694-1702.
    • (2005) Blood , vol.106 , pp. 1694-1702
    • Chauveau, C.1    Remy, S.2    Royer, P.J.3
  • 130
    • 33750375087 scopus 로고    scopus 로고
    • Heme oxygenase-1-mediated CD4+CD25high regulatory T cells suppress allergic airway inflammation
    • Xia Z.W., Zhong W.W., Xu L.Q., et al. Heme oxygenase-1-mediated CD4+CD25high regulatory T cells suppress allergic airway inflammation. J Immunol 2006, 177:5936-5945.
    • (2006) J Immunol , vol.177 , pp. 5936-5945
    • Xia, Z.W.1    Zhong, W.W.2    Xu, L.Q.3
  • 131
    • 33645945014 scopus 로고    scopus 로고
    • Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications
    • Ryter S.W., Alam J., Choi A.M. Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev 2006, 86:583-650.
    • (2006) Physiol Rev , vol.86 , pp. 583-650
    • Ryter, S.W.1    Alam, J.2    Choi, A.M.3
  • 132
    • 2942665771 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 before conditioning results in improved survival and reduced graft-versus-host disease after experimental allogeneic bone marrow transplantation
    • Gerbitz A., Ewing P., Wilke A., et al. Induction of heme oxygenase-1 before conditioning results in improved survival and reduced graft-versus-host disease after experimental allogeneic bone marrow transplantation. Biol Blood Marrow Transplant 2004, 10:461-472.
    • (2004) Biol Blood Marrow Transplant , vol.10 , pp. 461-472
    • Gerbitz, A.1    Ewing, P.2    Wilke, A.3
  • 133
    • 33645530745 scopus 로고    scopus 로고
    • Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis
    • Thimmulappa R.K., Lee H., Rangasamy T., et al. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. J Clin Invest 2006, 116:984-995.
    • (2006) J Clin Invest , vol.116 , pp. 984-995
    • Thimmulappa, R.K.1    Lee, H.2    Rangasamy, T.3
  • 134
    • 21144431523 scopus 로고    scopus 로고
    • The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling
    • Liby K., Hock T., Yore M.M., et al. The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling. Cancer Res 2005, 65:4789-4798.
    • (2005) Cancer Res , vol.65 , pp. 4789-4798
    • Liby, K.1    Hock, T.2    Yore, M.M.3
  • 135
    • 34247155249 scopus 로고    scopus 로고
    • The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality
    • Sun K., Li M., Konopleva M., et al. The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality. Biol Blood Marrow Transplant 2007, 13:521-529.
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 521-529
    • Sun, K.1    Li, M.2    Konopleva, M.3
  • 136
    • 53149153141 scopus 로고    scopus 로고
    • Role of MyD88 in TLR agonist-induced functional alterations of human adipose tissue-derived mesenchymal stem cells
    • Yu S., Cho H.H., Joo H.J., Bae Y.C., Jung J.S. Role of MyD88 in TLR agonist-induced functional alterations of human adipose tissue-derived mesenchymal stem cells. Mol Cell Biochem 2008, 317:143-150.
    • (2008) Mol Cell Biochem , vol.317 , pp. 143-150
    • Yu, S.1    Cho, H.H.2    Joo, H.J.3    Bae, Y.C.4    Jung, J.S.5
  • 137
    • 38349060182 scopus 로고    scopus 로고
    • Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling
    • Liotta F., Angeli R., Cosmi L., et al. Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. Stem Cells 2008, 26:279-289.
    • (2008) Stem Cells , vol.26 , pp. 279-289
    • Liotta, F.1    Angeli, R.2    Cosmi, L.3
  • 138
    • 38349077498 scopus 로고    scopus 로고
    • Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses
    • Tomchuck S.L., Zwezdaryk K.J., Coffelt S.B., Waterman R.S., Danka E.S., Scandurro A.B. Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses. Stem Cells 2008, 26:99-107.
    • (2008) Stem Cells , vol.26 , pp. 99-107
    • Tomchuck, S.L.1    Zwezdaryk, K.J.2    Coffelt, S.B.3    Waterman, R.S.4    Danka, E.S.5    Scandurro, A.B.6
  • 139
    • 65649089411 scopus 로고    scopus 로고
    • Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R
    • Opitz C.A., Litzenburger U.M., Lutz C., et al. Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R. Stem Cells 2009, 27:909-919.
    • (2009) Stem Cells , vol.27 , pp. 909-919
    • Opitz, C.A.1    Litzenburger, U.M.2    Lutz, C.3
  • 140
    • 33745076513 scopus 로고    scopus 로고
    • Antigen-presenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-gamma
    • Chan J.L., Tang K.C., Patel A.P., et al. Antigen-presenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-gamma. Blood 2006, 107:4817-4824.
    • (2006) Blood , vol.107 , pp. 4817-4824
    • Chan, J.L.1    Tang, K.C.2    Patel, A.P.3
  • 141
    • 33746889097 scopus 로고    scopus 로고
    • Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells
    • Krampera M., Cosmi L., Angeli R., et al. Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells. Stem Cells 2006, 24:386-398.
    • (2006) Stem Cells , vol.24 , pp. 386-398
    • Krampera, M.1    Cosmi, L.2    Angeli, R.3
  • 142
    • 34447298069 scopus 로고    scopus 로고
    • Interferon-gamma does not break, but promotes the immunosuppressive capacity of adult human mesenchymal stem cells
    • Ryan J.M., Barry F., Murphy J.M., Mahon B.P. Interferon-gamma does not break, but promotes the immunosuppressive capacity of adult human mesenchymal stem cells. Clin Exp Immunol 2007, 149:353-363.
    • (2007) Clin Exp Immunol , vol.149 , pp. 353-363
    • Ryan, J.M.1    Barry, F.2    Murphy, J.M.3    Mahon, B.P.4
  • 143
    • 70350512378 scopus 로고    scopus 로고
    • Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen presenting cell properties
    • Francois M., Romieu-Mourez R., Stock-Martineau S., Boivin M.N., Bramson J.L., Galipeau J. Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen presenting cell properties. Blood 2009, 114:2632-2638.
    • (2009) Blood , vol.114 , pp. 2632-2638
    • Francois, M.1    Romieu-Mourez, R.2    Stock-Martineau, S.3    Boivin, M.N.4    Bramson, J.L.5    Galipeau, J.6
  • 144
    • 67649209791 scopus 로고    scopus 로고
    • Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype
    • Romieu-Mourez R., Francois M., Boivin M.N., Bouchentouf M., Spaner D.E., Galipeau J. Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype. J Immunol 2009, 182:7963-7973.
    • (2009) J Immunol , vol.182 , pp. 7963-7973
    • Romieu-Mourez, R.1    Francois, M.2    Boivin, M.N.3    Bouchentouf, M.4    Spaner, D.E.5    Galipeau, J.6
  • 145
    • 58149326737 scopus 로고    scopus 로고
    • Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production
    • Nemeth K., Leelahavanichkul A., Yuen P.S., et al. Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 2009, 15:42-49.
    • (2009) Nat Med , vol.15 , pp. 42-49
    • Nemeth, K.1    Leelahavanichkul, A.2    Yuen, P.S.3
  • 146
    • 43049139914 scopus 로고    scopus 로고
    • Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells
    • Spaeth E., Klopp A., Dembinski J., Andreeff M., Marini F. Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells. Gene Ther 2008, 15:730-738.
    • (2008) Gene Ther , vol.15 , pp. 730-738
    • Spaeth, E.1    Klopp, A.2    Dembinski, J.3    Andreeff, M.4    Marini, F.5
  • 147
    • 22144491551 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets
    • Sordi V., Malosio M.L., Marchesi F., et al. Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood 2005, 106:419-427.
    • (2005) Blood , vol.106 , pp. 419-427
    • Sordi, V.1    Malosio, M.L.2    Marchesi, F.3
  • 148
    • 0038281370 scopus 로고    scopus 로고
    • Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates
    • Devine S.M., Cobbs C., Jennings M., Bartholomew A., Hoffman R. Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates. Blood 2003, 101:2999-3001.
    • (2003) Blood , vol.101 , pp. 2999-3001
    • Devine, S.M.1    Cobbs, C.2    Jennings, M.3    Bartholomew, A.4    Hoffman, R.5
  • 149
    • 37549036588 scopus 로고    scopus 로고
    • Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment
    • Klopp A.H., Spaeth E.L., Dembinski J.L., et al. Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment. Cancer Res 2007, 67:11687-11695.
    • (2007) Cancer Res , vol.67 , pp. 11687-11695
    • Klopp, A.H.1    Spaeth, E.L.2    Dembinski, J.L.3
  • 150
    • 33845277598 scopus 로고    scopus 로고
    • Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells
    • Ruster B., Gottig S., Ludwig R.J., et al. Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells. Blood 2006, 108:3938-3944.
    • (2006) Blood , vol.108 , pp. 3938-3944
    • Ruster, B.1    Gottig, S.2    Ludwig, R.J.3
  • 151
    • 33749078198 scopus 로고    scopus 로고
    • Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases
    • Son B.R., Marquez-Curtis L.A., Kucia M., et al. Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases. Stem Cells 2006, 24:1254-1264.
    • (2006) Stem Cells , vol.24 , pp. 1254-1264
    • Son, B.R.1    Marquez-Curtis, L.A.2    Kucia, M.3
  • 152
    • 0036172594 scopus 로고    scopus 로고
    • Inflammation is preceded by tumor necrosis factor-dependent infiltration of mesenchymal cells in experimental arthritis
    • Marinova-Mutafchieva L., Williams R.O., Funa K., Maini R.N., Zvaifler N.J. Inflammation is preceded by tumor necrosis factor-dependent infiltration of mesenchymal cells in experimental arthritis. Arthritis Rheum 2002, 46:507-513.
    • (2002) Arthritis Rheum , vol.46 , pp. 507-513
    • Marinova-Mutafchieva, L.1    Williams, R.O.2    Funa, K.3    Maini, R.N.4    Zvaifler, N.J.5
  • 153
    • 33846648734 scopus 로고    scopus 로고
    • Human mesenchymal stem cells constitutively express chemokines and chemokine receptors that can be upregulated by cytokines, IFN-beta, and Copaxone
    • Croitoru-Lamoury J., Lamoury F.M., Zaunders J.J., Veas L.A., Brew B.J. Human mesenchymal stem cells constitutively express chemokines and chemokine receptors that can be upregulated by cytokines, IFN-beta, and Copaxone. J Interferon Cytokine Res 2007, 27:53-64.
    • (2007) J Interferon Cytokine Res , vol.27 , pp. 53-64
    • Croitoru-Lamoury, J.1    Lamoury, F.M.2    Zaunders, J.J.3    Veas, L.A.4    Brew, B.J.5
  • 154
    • 33751542965 scopus 로고    scopus 로고
    • Sensitive balance of suppressing and activating effects of mesenchymal stem cells on T-cell proliferation
    • Fang L., Lange C., Engel M., Zander A.R., Fehse B. Sensitive balance of suppressing and activating effects of mesenchymal stem cells on T-cell proliferation. Transplantation 2006, 82:1370-1373.
    • (2006) Transplantation , vol.82 , pp. 1370-1373
    • Fang, L.1    Lange, C.2    Engel, M.3    Zander, A.R.4    Fehse, B.5
  • 155
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad F., Plence P., Bony C., et al. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 2003, 102:3837-3844.
    • (2003) Blood , vol.102 , pp. 3837-3844
    • Djouad, F.1    Plence, P.2    Bony, C.3
  • 156
    • 67649786655 scopus 로고    scopus 로고
    • Glycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migration
    • Sackstein R. Glycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migration. Immunol Rev 2009, 230:51-74.
    • (2009) Immunol Rev , vol.230 , pp. 51-74
    • Sackstein, R.1
  • 157
    • 37449023779 scopus 로고    scopus 로고
    • The contribution of endothelial activation and injury to end-organ toxicity following allogeneic hematopoietic stem cell transplantation
    • Cooke K.R., Jannin A., Ho V. The contribution of endothelial activation and injury to end-organ toxicity following allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2008, 14:23-32.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 23-32
    • Cooke, K.R.1    Jannin, A.2    Ho, V.3
  • 158
    • 77953613386 scopus 로고    scopus 로고
    • MAPCs modulate endotherial cell adhesion molecule cell surface expression following activation and reduce inflammation following AMI in rats
    • Abstract
    • Woda J., Lehman N., Cutrone R., et al. MAPCs modulate endotherial cell adhesion molecule cell surface expression following activation and reduce inflammation following AMI in rats. Basic Cardiovasc Sci Annu Conf 2009, Abstract.
    • (2009) Basic Cardiovasc Sci Annu Conf
    • Woda, J.1    Lehman, N.2    Cutrone, R.3
  • 159
    • 0031012138 scopus 로고    scopus 로고
    • P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflammed tissues
    • Austrup F., Vestweber D., Borges E., et al. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflammed tissues. Nature 1997, 385:81-83.
    • (1997) Nature , vol.385 , pp. 81-83
    • Austrup, F.1    Vestweber, D.2    Borges, E.3
  • 160
    • 33645741356 scopus 로고    scopus 로고
    • Identification of cutaneous lymphocyte-associated antigen as sialyl 6-sulfo Lewis X, a selectin ligand expressed on a subset of skin-homing helper memory T cells
    • Ohmori K., Fukui F., Kiso M., et al. Identification of cutaneous lymphocyte-associated antigen as sialyl 6-sulfo Lewis X, a selectin ligand expressed on a subset of skin-homing helper memory T cells. Blood 2006, 107:3197-3204.
    • (2006) Blood , vol.107 , pp. 3197-3204
    • Ohmori, K.1    Fukui, F.2    Kiso, M.3
  • 161
    • 37049028974 scopus 로고    scopus 로고
    • Favorable response to human adipose tissue-derived mesenchymal stem cells in steroid-refractory acute graft-versus-host disease
    • Fang B., Song Y., Liao L., Zhang Y., Zhao R.C. Favorable response to human adipose tissue-derived mesenchymal stem cells in steroid-refractory acute graft-versus-host disease. Transplant Proc 2007, 39:3358-3362.
    • (2007) Transplant Proc , vol.39 , pp. 3358-3362
    • Fang, B.1    Song, Y.2    Liao, L.3    Zhang, Y.4    Zhao, R.C.5
  • 162
    • 0042740515 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
    • Le Blanc K., Tammik L., Sundberg B., Haynesworth S.E., Ringden O. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand J Immunol 2003, 57:11-20.
    • (2003) Scand J Immunol , vol.57 , pp. 11-20
    • Le Blanc, K.1    Tammik, L.2    Sundberg, B.3    Haynesworth, S.E.4    Ringden, O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.