메뉴 건너뛰기




Volumn 262, Issue 5, 2007, Pages 509-525

Immunomodulation by mesenchymal stem cells and clinical experience

Author keywords

Acute graft versus host disease; Haematopoietic stem cell transplantation; Immunomodulation; Mesenchymal stem cells; Tissue toxicity

Indexed keywords

ALLOANTIGEN; MITOGENIC AGENT;

EID: 35448996504     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2007.01844.x     Document Type: Review
Times cited : (637)

References (117)
  • 1
    • 0014261390 scopus 로고
    • Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissues
    • Friedenstein AJ, Petrakova KV, Kurolesova AI, Frolova GP. Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissues. Transplantation 1968 6 : 230 47.
    • (1968) Transplantation , vol.6 , pp. 230-47
    • Friedenstein, A.J.1    Petrakova, K.V.2    Kurolesova, A.I.3    Frolova, G.P.4
  • 2
    • 0017103248 scopus 로고
    • Precursor cells of mechanocytes
    • Friedenstein AJ. Precursor cells of mechanocytes. Int Rev Cytol 1976 47 : 327 59.
    • (1976) Int Rev Cytol , vol.47 , pp. 327-59
    • Friedenstein, A.J.1
  • 3
    • 84990622726 scopus 로고
    • Bone marrow osteogenic stem cells: In vitro cultivation and transplantation in diffusion chambers
    • Friedenstein AJ, Chailakhyan RK, Gerasimov UV. Bone marrow osteogenic stem cells: in vitro cultivation and transplantation in diffusion chambers. Cell Tissue Kinet 1987 20 : 263 72.
    • (1987) Cell Tissue Kinet , vol.20 , pp. 263-72
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Gerasimov, U.V.3
  • 4
    • 0024252149 scopus 로고
    • Stromal stem cells: Marrow-derived osteogenic precursors
    • Owen M, Friedenstein AJ. Stromal stem cells: marrow-derived osteogenic precursors. Ciba Found Symp 1988 136 : 42 60.
    • (1988) Ciba Found Symp , vol.136 , pp. 42-60
    • Owen, M.1    Friedenstein, A.J.2
  • 5
    • 0034079140 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells in human umbilical cord blood
    • Erices A, Conget P, Minguell JJ. Mesenchymal progenitor cells in human umbilical cord blood. Br J Haematol 2000 109 : 235 42.
    • (2000) Br J Haematol , vol.109 , pp. 235-42
    • Erices, A.1    Conget, P.2    Minguell, J.J.3
  • 6
    • 0035889146 scopus 로고    scopus 로고
    • Identification of mesenchymal stem/progenitor cells in human first- trimester fetal blood, liver, and bone marrow
    • Campagnoli C, Roberts IA, Kumar S, Bennett PR, Bellantuono I, Fisk NM. Identification of mesenchymal stem/progenitor cells in human first- trimester fetal blood, liver, and bone marrow. Blood 2001 98 : 2396 402.
    • (2001) Blood , vol.98 , pp. 2396-402
    • Campagnoli, C.1    Roberts, I.A.2    Kumar, S.3    Bennett, P.R.4    Bellantuono, I.5    Fisk, N.M.6
  • 7
    • 18444374992 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice
    • Noort WA, Kruisselbrink AB, in't Anker PS et al. Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol 2002 30 : 870 8.
    • (2002) Exp Hematol , vol.30 , pp. 870-8
    • Noort, W.A.1    Kruisselbrink, A.B.2    In'T Anker, P.S.3
  • 8
    • 10744228149 scopus 로고    scopus 로고
    • Comparison of multi-lineage cells from human adipose tissue and bone marrow
    • De Ugarte DA, Morizono K, Elbarbary A et al. Comparison of multi-lineage cells from human adipose tissue and bone marrow. Cells Tissues Organs 2003 174 : 101 9.
    • (2003) Cells Tissues Organs , vol.174 , pp. 101-9
    • De Ugarte, D.A.1    Morizono, K.2    Elbarbary, A.3
  • 9
    • 84989485234 scopus 로고
    • The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells
    • Friedenstein AJ, Chailakhjan RK, Lalykina KS. The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet 1970 3 : 393 403.
    • (1970) Cell Tissue Kinet , vol.3 , pp. 393-403
    • Friedenstein, A.J.1    Chailakhjan, R.K.2    Lalykina, K.S.3
  • 10
    • 17344387788 scopus 로고
    • Dynamics of formation of fibroblast colonies in monolayer cultures of bone marrow according to H3-thymidine incorporation data
    • Keilis-Borok IV, Latsinik NV, Epikhina S, Fridenshtein A. Dynamics of formation of fibroblast colonies in monolayer cultures of bone marrow according to H3-thymidine incorporation data. Tsitologiia 1971 13 : 1402 9.
    • (1971) Tsitologiia , vol.13 , pp. 1402-9
    • Keilis-Borok, I.V.1    Latsinik, N.V.2    Epikhina, S.3    Fridenshtein, A.4
  • 11
    • 0016882174 scopus 로고
    • Proliferative activity of stromal cells - Bone marrow precursors possessing clonogenic properties
    • Epikhina S, Latsinik NV. Proliferative activity of stromal cells - bone marrow precursors possessing clonogenic properties. Bull Exp Biol Med 1976 81 : 55 7.
    • (1976) Bull Exp Biol Med , vol.81 , pp. 55-7
    • Epikhina, S.1    Latsinik, N.V.2
  • 12
    • 0018947660 scopus 로고
    • Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny
    • Castro-Malaspina H, Gay RE, Resnick G et al. Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny. Blood 1980 56 : 289 301.
    • (1980) Blood , vol.56 , pp. 289-301
    • Castro-Malaspina, H.1    Gay, R.E.2    Resnick, G.3
  • 13
    • 0025741349 scopus 로고
    • Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1
    • Simmons PJ, Torok-Storb B. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood 1991 78 : 55 62.
    • (1991) Blood , vol.78 , pp. 55-62
    • Simmons, P.J.1    Torok-Storb, B.2
  • 14
    • 0028102611 scopus 로고
    • The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors
    • Gronthos S, Graves SE, Ohta S, Simmons PJ. The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors. Blood 1994 84 : 4164 73.
    • (1994) Blood , vol.84 , pp. 4164-73
    • Gronthos, S.1    Graves, S.E.2    Ohta, S.3    Simmons, P.J.4
  • 15
    • 0028720896 scopus 로고
    • Isolation, characterization and functional activity of human marrow stromal progenitors in hemopoiesis
    • Simmons PJ, Gronthos S, Zannettino A, Ohta S, Graves S. Isolation, characterization and functional activity of human marrow stromal progenitors in hemopoiesis. Prog Clin Biol Res 1994 389 : 271 80.
    • (1994) Prog Clin Biol Res , vol.389 , pp. 271-80
    • Simmons, P.J.1    Gronthos, S.2    Zannettino, A.3    Ohta, S.4    Graves, S.5
  • 16
    • 0028966028 scopus 로고
    • The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro
    • Gronthos S, Simmons PJ. The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro. Blood 1995 85 : 929 40.
    • (1995) Blood , vol.85 , pp. 929-40
    • Gronthos, S.1    Simmons, P.J.2
  • 17
    • 0036901021 scopus 로고    scopus 로고
    • Isolation and characterization of bone marrow multipotential mesenchymal progenitor cells
    • Jones EA, Kinsey SE, English A et al. Isolation and characterization of bone marrow multipotential mesenchymal progenitor cells. Arthritis Rheum 2002 46 : 3349 60.
    • (2002) Arthritis Rheum , vol.46 , pp. 3349-60
    • Jones, E.A.1    Kinsey, S.E.2    English, A.3
  • 18
    • 0038664242 scopus 로고    scopus 로고
    • Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow
    • Gronthos S, Zannettino AC, Hay SJ et al. Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. J Cell Sci 2003 116 : 1827 35.
    • (2003) J Cell Sci , vol.116 , pp. 1827-35
    • Gronthos, S.1    Zannettino, A.C.2    Hay, S.J.3
  • 19
    • 0034047440 scopus 로고    scopus 로고
    • Proliferation kinetics and differentiation potential of ex vivo expanded human bone marrow stromal cells: Implications for their use in cell therapy
    • Banfi A, Muraglia A, Dozin B, Mastrogiacomo M, Cancedda R, Quarto R. Proliferation kinetics and differentiation potential of ex vivo expanded human bone marrow stromal cells: implications for their use in cell therapy. Exp Hematol 2000 28 : 707 15.
    • (2000) Exp Hematol , vol.28 , pp. 707-15
    • Banfi, A.1    Muraglia, A.2    Dozin, B.3    Mastrogiacomo, M.4    Cancedda, R.5    Quarto, R.6
  • 20
    • 0036892057 scopus 로고    scopus 로고
    • Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells
    • Banfi A, Bianchi G, Notaro R, Luzzatto L, Cancedda R, Quarto R. Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells. Tissue Eng 2002 8 : 901 10.
    • (2002) Tissue Eng , vol.8 , pp. 901-10
    • Banfi, A.1    Bianchi, G.2    Notaro, R.3    Luzzatto, L.4    Cancedda, R.5    Quarto, R.6
  • 21
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999 284 : 143 7.
    • (1999) Science , vol.284 , pp. 143-7
    • Pittenger, M.F.1    MacKay, A.M.2    Beck, S.C.3
  • 22
    • 0034056758 scopus 로고    scopus 로고
    • Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model
    • Muraglia A, Cancedda R, Quarto R. Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model. J Cell Sci 2000 113 (Pt 7) : 1161 6.
    • (2000) J Cell Sci , vol.1137 , pp. 1161-6
    • Muraglia, A.1    Cancedda, R.2    Quarto, R.3
  • 23
    • 0034805960 scopus 로고    scopus 로고
    • MicroSAGE analysis of 2,353 expressed genes in a single cell-derived colony of undifferentiated human mesenchymal stem cells reveals mRNAs of multiple cell lineages
    • Tremain N, Korkko J, Ibberson D, Kopen GC, DiGirolamo C, Phinney DG. MicroSAGE analysis of 2,353 expressed genes in a single cell-derived colony of undifferentiated human mesenchymal stem cells reveals mRNAs of multiple cell lineages. Stem Cells 2001 19 : 408 18.
    • (2001) Stem Cells , vol.19 , pp. 408-18
    • Tremain, N.1    Korkko, J.2    Ibberson, D.3    Kopen, G.C.4    Digirolamo, C.5    Phinney, D.G.6
  • 24
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 1997 276 : 71 4.
    • (1997) Science , vol.276 , pp. 71-4
    • Prockop, D.J.1
  • 25
    • 0033678140 scopus 로고    scopus 로고
    • Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
    • Liechty KW, MacKenzie TC, Shaaban AF et al. Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med 2000 6 : 1282 6.
    • (2000) Nat Med , vol.6 , pp. 1282-6
    • Liechty, K.W.1    MacKenzie, T.C.2    Shaaban, A.F.3
  • 26
    • 3042643326 scopus 로고    scopus 로고
    • Rat adult stem cells (marrow stromal cells) engraft and differentiate in chick embryos without evidence of cell fusion
    • Pochampally RR, Neville BT, Schwarz EJ, Li MM, Prockop DJ. Rat adult stem cells (marrow stromal cells) engraft and differentiate in chick embryos without evidence of cell fusion. Proc Natl Acad Sci U S A 2004 101 : 9282 5.
    • (2004) Proc Natl Acad Sci U S a , vol.101 , pp. 9282-5
    • Pochampally, R.R.1    Neville, B.T.2    Schwarz, E.J.3    Li, M.M.4    Prockop, D.J.5
  • 27
    • 0026228558 scopus 로고
    • Mesenchymal stem cells
    • Caplan AI. Mesenchymal stem cells. J Orthop Res 1991 9 : 641 50.
    • (1991) J Orthop Res , vol.9 , pp. 641-50
    • Caplan, A.I.1
  • 28
    • 0035010796 scopus 로고    scopus 로고
    • The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion
    • Gao J, Dennis JE, Muzic RF, Lundberg M, Caplan AI. The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues Organs 2001 169 : 12 20.
    • (2001) Cells Tissues Organs , vol.169 , pp. 12-20
    • Gao, J.1    Dennis, J.E.2    Muzic, R.F.3    Lundberg, M.4    Caplan, A.I.5
  • 29
    • 1942528355 scopus 로고    scopus 로고
    • Mesenchymal stem cells home to injured tissues when co-infused with hematopoietic cells to treat a radiation-induced multi-organ failure syndrome
    • Chapel A, Bertho JM, Bensidhoum M et al. Mesenchymal stem cells home to injured tissues when co-infused with hematopoietic cells to treat a radiation-induced multi-organ failure syndrome. J Gene Med 2003 5 : 1028 38.
    • (2003) J Gene Med , vol.5 , pp. 1028-38
    • Chapel, A.1    Bertho, J.M.2    Bensidhoum, M.3
  • 30
    • 0038281370 scopus 로고    scopus 로고
    • Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates
    • Devine SM, Cobbs C, Jennings M, Bartholomew A, Hoffman R. Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates. Blood 2003 101 : 2999 3001.
    • (2003) Blood , vol.101 , pp. 2999-3001
    • Devine, S.M.1    Cobbs, C.2    Jennings, M.3    Bartholomew, A.4    Hoffman, R.5
  • 31
    • 2942536282 scopus 로고    scopus 로고
    • Intervertebral disc cell therapy for regeneration: Mesenchymal stem cell implantation in rat intervertebral discs
    • Crevensten G, Walsh AJ, Ananthakrishnan D et al. Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs. Ann Biomed Eng 2004 32 : 430 4.
    • (2004) Ann Biomed Eng , vol.32 , pp. 430-4
    • Crevensten, G.1    Walsh, A.J.2    Ananthakrishnan, D.3
  • 32
    • 0141889330 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cells regenerate bone in a critical-sized canine segmental defect
    • Arinzeh TL, Peter SJ, Archambault MP et al. Allogeneic mesenchymal stem cells regenerate bone in a critical-sized canine segmental defect. J Bone Joint Surg Am 2003 85-A : 1927 35.
    • (2003) J Bone Joint Surg Am , vol.85 , pp. 1927-35
    • Arinzeh, T.L.1    Peter, S.J.2    Archambault, M.P.3
  • 33
    • 10744222737 scopus 로고    scopus 로고
    • Gene targeting in stem cells from individuals with osteogenesis imperfecta
    • Chamberlain JR, Schwarze U, Wang PR et al. Gene targeting in stem cells from individuals with osteogenesis imperfecta. Science 2004 303 : 1198 201.
    • (2004) Science , vol.303 , pp. 1198-201
    • Chamberlain, J.R.1    Schwarze, U.2    Wang, P.R.3
  • 34
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • Toma C, Pittenger MF, Cahill KS, Byrne BJ, Kessler PD. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002 105 : 93 8.
    • (2002) Circulation , vol.105 , pp. 93-8
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3    Byrne, B.J.4    Kessler, P.D.5
  • 36
    • 0345306695 scopus 로고    scopus 로고
    • Potential use of stem cells in neuroreplacement therapies for neurodegenerative diseases
    • Sugaya K. Potential use of stem cells in neuroreplacement therapies for neurodegenerative diseases. Int Rev Cytol 2003 228 : 1 30.
    • (2003) Int Rev Cytol , vol.228 , pp. 1-30
    • Sugaya, K.1
  • 37
    • 0348156896 scopus 로고    scopus 로고
    • Efficiency of adenoviral vector mediated CTLA4Ig gene delivery into mesenchymal stem cells
    • Deng Y, Guo X, Yuan Q, Li S. Efficiency of adenoviral vector mediated CTLA4Ig gene delivery into mesenchymal stem cells. Chin Med J (Engl) 2003 116 : 1649 54.
    • (2003) Chin Med J (Engl) , vol.116 , pp. 1649-54
    • Deng, Y.1    Guo, X.2    Yuan, Q.3    Li, S.4
  • 38
    • 0037478581 scopus 로고    scopus 로고
    • Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects
    • Ortiz LA, Gambelli F, McBride C et al. Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects. Proc Natl Acad Sci U S A 2003 100 : 8407 11.
    • (2003) Proc Natl Acad Sci U S a , vol.100 , pp. 8407-11
    • Ortiz, L.A.1    Gambelli, F.2    McBride, C.3
  • 39
    • 0029867151 scopus 로고    scopus 로고
    • Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL-1 alpha
    • Haynesworth SE, Baber MA, Caplan AI. Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alpha. J Cell Physiol 1996 166 : 585 92.
    • (1996) J Cell Physiol , vol.166 , pp. 585-92
    • Haynesworth, S.E.1    Baber, M.A.2    Caplan, A.I.3
  • 40
    • 0031861531 scopus 로고    scopus 로고
    • Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells
    • Majumdar MK, Thiede MA, Mosca JD, Moorman M, Gerson SL. Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells. J Cell Physiol 1998 176 : 57 66.
    • (1998) J Cell Physiol , vol.176 , pp. 57-66
    • Majumdar, M.K.1    Thiede, M.A.2    Mosca, J.D.3    Moorman, M.4    Gerson, S.L.5
  • 41
    • 0032836513 scopus 로고    scopus 로고
    • Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero
    • Almeida-Porada G, Flake AW, Glimp HA, Zanjani ED. Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero. Exp Hematol 1999 27 : 1569 75.
    • (1999) Exp Hematol , vol.27 , pp. 1569-75
    • Almeida-Porada, G.1    Flake, A.W.2    Glimp, H.A.3    Zanjani, E.D.4
  • 42
    • 0033304715 scopus 로고    scopus 로고
    • Human mesenchymal stem cells promote human osteoclast differentiation from CD34+ bone marrow hematopoietic progenitors
    • Mbalaviele G, Jaiswal N, Meng A, Cheng L, Van Den Bos C, Thiede M. Human mesenchymal stem cells promote human osteoclast differentiation from CD34+ bone marrow hematopoietic progenitors. Endocrinology 1999 140 : 3736 43.
    • (1999) Endocrinology , vol.140 , pp. 3736-43
    • Mbalaviele, G.1    Jaiswal, N.2    Meng, A.3    Cheng, L.4    Van Den Bos, C.5    Thiede, M.6
  • 43
    • 0037562968 scopus 로고    scopus 로고
    • Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice
    • Angelopoulou M, Novelli E, Grove JE et al. Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice. Exp Hematol 2003 31 : 413 20.
    • (2003) Exp Hematol , vol.31 , pp. 413-20
    • Angelopoulou, M.1    Novelli, E.2    Grove, J.E.3
  • 44
    • 0141484486 scopus 로고    scopus 로고
    • Nonexpanded primary lung and bone marrow-derived mesenchymal cells promote the engraftment of umbilical cord blood-derived CD34(+) cells in NOD/SCID mice
    • in 't Anker PS, Noort WA, Kruisselbrink AB et al. Nonexpanded primary lung and bone marrow-derived mesenchymal cells promote the engraftment of umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol 2003 31 : 881 9.
    • (2003) Exp Hematol , vol.31 , pp. 881-9
    • In Anker 'T, P.S.1    Noort, W.A.2    Kruisselbrink, A.B.3
  • 45
    • 1842483153 scopus 로고    scopus 로고
    • Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation
    • Maitra B, Szekely E, Gjini K et al. Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation. Bone Marrow Transplant 2004 33 : 597 604.
    • (2004) Bone Marrow Transplant , vol.33 , pp. 597-604
    • Maitra, B.1    Szekely, E.2    Gjini, K.3
  • 46
    • 0036142769 scopus 로고    scopus 로고
    • Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
    • Bartholomew A, Sturgeon C, Siatskas M et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol 2002 30 : 42 8.
    • (2002) Exp Hematol , vol.30 , pp. 42-8
    • Bartholomew, A.1    Sturgeon, C.2    Siatskas, M.3
  • 47
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • Krampera M, Glennie S, Dyson J et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 2003 101 : 3722 9.
    • (2003) Blood , vol.101 , pp. 3722-9
    • Krampera, M.1    Glennie, S.2    Dyson, J.3
  • 48
    • 0042740515 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
    • Le Blanc K, Tammik L, Sundberg B, Haynesworth SE, Ringdén O. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand J Immunol 2003 57 : 11 20.
    • (2003) Scand J Immunol , vol.57 , pp. 11-20
    • Le Blanc, K.1    Tammik, L.2    Sundberg, B.3    Haynesworth, S.E.4    Ringdén, O.5
  • 49
    • 0037442264 scopus 로고    scopus 로고
    • Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation
    • Tse WT, Pendleton JD, Beyer WM, Egalka MC, Guinan EC. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation 2003 75 : 389 97.
    • (2003) Transplantation , vol.75 , pp. 389-97
    • Tse, W.T.1    Pendleton, J.D.2    Beyer, W.M.3    Egalka, M.C.4    Guinan, E.C.5
  • 50
    • 20844440562 scopus 로고    scopus 로고
    • Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms
    • Togel F, Hu Z, Weiss K, Isaac J, Lange C, Westenfelder C. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 2005 289 : F31 42.
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Togel, F.1    Hu, Z.2    Weiss, K.3    Isaac, J.4    Lange, C.5    Westenfelder, C.6
  • 51
    • 23944519424 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy
    • Zappia E, Casazza S, Pedemonte E et al. Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy. Blood 2005 106 : 1755 61.
    • (2005) Blood , vol.106 , pp. 1755-61
    • Zappia, E.1    Casazza, S.2    Pedemonte, E.3
  • 52
    • 0032768790 scopus 로고    scopus 로고
    • Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells
    • Conget PA, Minguell JJ. Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. J Cell Physiol 1999 181 : 67 73.
    • (1999) J Cell Physiol , vol.181 , pp. 67-73
    • Conget, P.A.1    Minguell, J.J.2
  • 53
    • 0033824164 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Biology and potential clinical uses
    • Deans RJ, Moseley AB. Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol 2000 28 : 875 84.
    • (2000) Exp Hematol , vol.28 , pp. 875-84
    • Deans, R.J.1    Moseley, A.B.2
  • 54
    • 0141862027 scopus 로고    scopus 로고
    • Differential expression of stem cell mobilization-associated molecules on multi-lineage cells from adipose tissue and bone marrow
    • De Ugarte DA, Alfonso Z, Zuk PA et al. Differential expression of stem cell mobilization-associated molecules on multi-lineage cells from adipose tissue and bone marrow. Immunol Lett 2003 89 : 267 70.
    • (2003) Immunol Lett , vol.89 , pp. 267-70
    • De Ugarte, D.A.1    Alfonso, Z.2    Zuk, P.A.3
  • 55
    • 0141484485 scopus 로고    scopus 로고
    • HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells
    • Le Blanc K, Tammik L, Zetterberg E, Ringdén O. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Haematol 2003 31 : 890 6.
    • (2003) Exp Haematol , vol.31 , pp. 890-6
    • Le Blanc, K.1    Tammik, L.2    Zetterberg, E.3    Ringdén, O.4
  • 56
    • 17744365164 scopus 로고    scopus 로고
    • T cell responses to allogeneic human mesenchymal stem cells: Immunogenicity, tolerance, and suppression
    • Klyushnenkova E, Mosca JD, Zernetkina V et al. T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression. J Biomed Sci 2005 12 : 47 57.
    • (2005) J Biomed Sci , vol.12 , pp. 47-57
    • Klyushnenkova, E.1    Mosca, J.D.2    Zernetkina, V.3
  • 57
    • 0141886188 scopus 로고    scopus 로고
    • Veto-like activity of mesenchymal stem cells: Functional discrimination between cellular responses to alloantigens and recall antigens
    • Potian JA, Aviv H, Ponzio NM, Harrison JS, Rameshwar P. Veto-like activity of mesenchymal stem cells: functional discrimination between cellular responses to alloantigens and recall antigens. J Immunol 2003 171 : 3426 34.
    • (2003) J Immunol , vol.171 , pp. 3426-34
    • Potian, J.A.1    Aviv, H.2    Ponzio, N.M.3    Harrison, J.S.4    Rameshwar, P.5
  • 58
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness
    • Beyth S, Borovsky Z, Mevorach D et al. Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood 2005 105 : 2214 9.
    • (2005) Blood , vol.105 , pp. 2214-9
    • Beyth, S.1    Borovsky, Z.2    Mevorach, D.3
  • 59
    • 4344683220 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes
    • Le Blanc K, Rasmusson I, Götherström C et al. Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes. Scand J Immunol 2004 60 : 307 15.
    • (2004) Scand J Immunol , vol.60 , pp. 307-15
    • Le Blanc, K.1    Rasmusson, I.2    Götherström, C.3
  • 60
    • 0242300602 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
    • Rasmusson I, Ringden O, Sundberg B, Le Blanc K. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 2003 76 : 1208 13.
    • (2003) Transplantation , vol.76 , pp. 1208-13
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    Le Blanc, K.4
  • 61
    • 4644232573 scopus 로고    scopus 로고
    • Human mesenchymal stem cells suppress induction of cytotoxic response to alloantigens
    • Angoulvant D, Clerc A, Benchalal S et al. Human mesenchymal stem cells suppress induction of cytotoxic response to alloantigens. Biorheology 2004 41 : 469 76.
    • (2004) Biorheology , vol.41 , pp. 469-76
    • Angoulvant, D.1    Clerc, A.2    Benchalal, S.3
  • 62
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M, Carlo-Stella C, Magni M et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002 99 : 3838 43.
    • (2002) Blood , vol.99 , pp. 3838-43
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3
  • 63
    • 15044348816 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms
    • Rasmusson I, Ringden O, Sundberg B, Le Blanc K. Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms. Exp Cell Res 2005 305 : 33 41.
    • (2005) Exp Cell Res , vol.305 , pp. 33-41
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    Le Blanc, K.4
  • 64
    • 21244445059 scopus 로고    scopus 로고
    • Suppression of human peripheral blood lymphocyte proliferation by immortalized mesenchymal stem cells derived from bone marrow of Banna Minipig inbred-line
    • Liu J, Lu XF, Wan L et al. Suppression of human peripheral blood lymphocyte proliferation by immortalized mesenchymal stem cells derived from bone marrow of Banna Minipig inbred-line. Transplant Proc 2004 36 : 3272 5.
    • (2004) Transplant Proc , vol.36 , pp. 3272-5
    • Liu, J.1    Lu, X.F.2    Wan, L.3
  • 65
    • 15944376184 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells
    • Glennie S, Soeiro I, Dyson PJ, Lam EW, Dazzi F. Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells. Blood 2005 105 : 2821 7.
    • (2005) Blood , vol.105 , pp. 2821-7
    • Glennie, S.1    Soeiro, I.2    Dyson, P.J.3    Lam, E.W.4    Dazzi, F.5
  • 66
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995 155 : 1151 64.
    • (1995) J Immunol , vol.155 , pp. 1151-64
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 68
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005 105 : 1815 22.
    • (2005) Blood , vol.105 , pp. 1815-22
    • Aggarwal, S.1    Pittenger, M.F.2
  • 69
    • 17844391825 scopus 로고    scopus 로고
    • Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype
    • Maccario R, Podesta M, Moretta A et al. Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype. Haematologica 2005 90 : 516 25.
    • (2005) Haematologica , vol.90 , pp. 516-25
    • MacCario, R.1    Podesta, M.2    Moretta, A.3
  • 70
    • 22144473736 scopus 로고    scopus 로고
    • Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells
    • Groh ME, Maitra B, Szekely E, Koc ON. Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells. Exp Hematol 2005 33 : 928 34.
    • (2005) Exp Hematol , vol.33 , pp. 928-34
    • Groh, M.E.1    Maitra, B.2    Szekely, E.3    Koc, O.N.4
  • 71
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad F, Plence P, Bony C et al. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 2003 102 : 3837 44.
    • (2003) Blood , vol.102 , pp. 3837-44
    • Djouad, F.1    Plence, P.2    Bony, C.3
  • 72
    • 18844404360 scopus 로고    scopus 로고
    • Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway
    • Augello A, Tasso R, Negrini SM et al. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur J Immunol 2005 35 : 1482 90.
    • (2005) Eur J Immunol , vol.35 , pp. 1482-90
    • Augello, A.1    Tasso, R.2    Negrini, S.M.3
  • 73
    • 0032555614 scopus 로고    scopus 로고
    • Prevention of allogeneic fetal rejection by tryptophan catabolism
    • Munn DH, Zhou M, Attwood JT et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 1998 281 : 1191 3.
    • (1998) Science , vol.281 , pp. 1191-3
    • Munn, D.H.1    Zhou, M.2    Attwood, J.T.3
  • 74
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 2004 103 : 4619 21.
    • (2004) Blood , vol.103 , pp. 4619-21
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 75
    • 4644265937 scopus 로고    scopus 로고
    • Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2- overexpressing glioma
    • Akasaki Y, Liu G, Chung NH, Ehtesham M, Black KL, Yu JS. Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2-overexpressing glioma. J Immunol 2004 173 : 4352 9.
    • (2004) J Immunol , vol.173 , pp. 4352-9
    • Akasaki, Y.1    Liu, G.2    Chung, N.H.3    Ehtesham, M.4    Black, K.L.5    Yu, J.S.6
  • 76
    • 3442884490 scopus 로고    scopus 로고
    • Regulation of bone morphogenetic protein-2 expression by endogenous prostaglandin E2 in human mesenchymal stem cells
    • Arikawa T, Omura K, Morita I. Regulation of bone morphogenetic protein-2 expression by endogenous prostaglandin E2 in human mesenchymal stem cells. J Cell Physiol 2004 200 : 400 6.
    • (2004) J Cell Physiol , vol.200 , pp. 400-6
    • Arikawa, T.1    Omura, K.2    Morita, I.3
  • 77
    • 30144440925 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate B-cell functions
    • Corcione A, Benvenuto F, Ferretti E et al. Human mesenchymal stem cells modulate B-cell functions. Blood 2006 107 : 367 72.
    • (2006) Blood , vol.107 , pp. 367-72
    • Corcione, A.1    Benvenuto, F.2    Ferretti, E.3
  • 78
    • 0015108294 scopus 로고
    • Osteogenic precursor cells of bone marrow in radiation chimeras
    • Friedenstein A, Kuralesova AI. Osteogenic precursor cells of bone marrow in radiation chimeras. Transplantation 1971 12 : 99 108.
    • (1971) Transplantation , vol.12 , pp. 99-108
    • Friedenstein, A.1    Kuralesova, A.I.2
  • 79
    • 18544371666 scopus 로고    scopus 로고
    • Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells
    • Jiang XX, Zhang Y, Liu B et al. Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Blood 2005 105 : 4120 6.
    • (2005) Blood , vol.105 , pp. 4120-6
    • Jiang, X.X.1    Zhang, Y.2    Liu, B.3
  • 80
    • 2942562525 scopus 로고    scopus 로고
    • Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells
    • Zhang W, Ge W, Li C et al. Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells. Stem Cells Dev 2004 13 : 263 71.
    • (2004) Stem Cells Dev , vol.13 , pp. 263-71
    • Zhang, W.1    Ge, W.2    Li, C.3
  • 81
    • 10344239885 scopus 로고    scopus 로고
    • Stromal cells direct local differentiation of regulatory dendritic cells
    • Svensson M, Maroof A, Ato M, Kaye PM. Stromal cells direct local differentiation of regulatory dendritic cells. Immunity 2004 21 : 805 16.
    • (2004) Immunity , vol.21 , pp. 805-16
    • Svensson, M.1    Maroof, A.2    Ato, M.3    Kaye, P.M.4
  • 82
    • 0018089471 scopus 로고
    • Activation of human B and T lymphocytes by protein a of Staphylococcus aureus
    • Ringdén O, Rynnel-Dagöö B. Activation of human B and T lymphocytes by protein A of Staphylococcus aureus. Eur J Immunol 1978 8 : 47 52.
    • (1978) Eur J Immunol , vol.8 , pp. 47-52
    • Ringdén, O.1    Rynnel-Dagöö, B.2
  • 83
    • 33947593728 scopus 로고    scopus 로고
    • Mesenchymal stem cells stimulate antibody secretion in human B cells
    • Rasmusson I, Le Blanc K, Sundberg B, Ringden O. Mesenchymal stem cells stimulate antibody secretion in human B cells. Scand J Immunol 2007 65 : 336 43.
    • (2007) Scand J Immunol , vol.65 , pp. 336-43
    • Rasmusson, I.1    Le Blanc, K.2    Sundberg, B.3    Ringden, O.4
  • 84
    • 0037648864 scopus 로고    scopus 로고
    • In vivo magnetic resonance imaging of mesenchymal stem cells in myocardial infarction
    • Kraitchman DL, Heldman AW, Atalar E et al. In vivo magnetic resonance imaging of mesenchymal stem cells in myocardial infarction. Circulation 2003 107 : 2290 3.
    • (2003) Circulation , vol.107 , pp. 2290-3
    • Kraitchman, D.L.1    Heldman, A.W.2    Atalar, E.3
  • 85
    • 0037325716 scopus 로고    scopus 로고
    • Engraftment of allogeneic mesenchymal stem cells in the bone marrow of a patient with severe idiopathic aplastic anemia improves stroma
    • Fouillard L, Bensidhoum M, Bories D et al. Engraftment of allogeneic mesenchymal stem cells in the bone marrow of a patient with severe idiopathic aplastic anemia improves stroma. Leukemia 2003 17 : 474 6.
    • (2003) Leukemia , vol.17 , pp. 474-6
    • Fouillard, L.1    Bensidhoum, M.2    Bories, D.3
  • 86
    • 20544455396 scopus 로고    scopus 로고
    • Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta
    • Le Blanc K, Götherström C, Ringdén O et al. Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta. Transplantation 2005 79 : 1607 14.
    • (2005) Transplantation , vol.79 , pp. 1607-14
    • Le Blanc, K.1    Götherström, C.2    Ringdén, O.3
  • 87
    • 28844483809 scopus 로고    scopus 로고
    • Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice
    • Eliopoulos N, Stagg J, Lejeune L, Pommey S, Galipeau J. Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice. Blood 2005 106 : 4057 65.
    • (2005) Blood , vol.106 , pp. 4057-65
    • Eliopoulos, N.1    Stagg, J.2    Lejeune, L.3    Pommey, S.4    Galipeau, J.5
  • 88
    • 0032584132 scopus 로고    scopus 로고
    • Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts
    • Azizi SA, Stokes D, Augelli BJ, DiGirolamo C, Prockop DJ. Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts. Proc Natl Acad Sci U S A 1998 95 : 3908 13.
    • (1998) Proc Natl Acad Sci U S a , vol.95 , pp. 3908-13
    • Azizi, S.A.1    Stokes, D.2    Augelli, B.J.3    Digirolamo, C.4    Prockop, D.J.5
  • 89
    • 0036304472 scopus 로고    scopus 로고
    • Xenotransplant cardiac chimera: Immune tolerance of adult stem cells
    • discussion 24.
    • Saito T, Kuang JQ, Bittira B, Al-Khaldi A, Chiu RC. Xenotransplant cardiac chimera: immune tolerance of adult stem cells. Ann Thorac Surg 2002 74 : 19 24 discussion 24.
    • (2002) Ann Thorac Surg , vol.74 , pp. 19-24
    • Saito, T.1    Kuang, J.Q.2    Bittira, B.3    Al-Khaldi, A.4    Chiu, R.C.5
  • 90
    • 2342427573 scopus 로고    scopus 로고
    • Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium
    • Grinnemo KH, Mansson A, Dellgren G et al. Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium. J Thorac Cardiovasc Surg 2004 127 : 1293 300.
    • (2004) J Thorac Cardiovasc Surg , vol.127 , pp. 1293-300
    • Grinnemo, K.H.1    Mansson, A.2    Dellgren, G.3
  • 91
    • 1642391602 scopus 로고    scopus 로고
    • Human mesenchymal stem cells form Purkinje fibers in fetal sheep heart
    • Airey JA, Almeida-Porada G, Colletti EJ et al. Human mesenchymal stem cells form Purkinje fibers in fetal sheep heart. Circulation 2004 109 : 1401 7.
    • (2004) Circulation , vol.109 , pp. 1401-7
    • Airey, J.A.1    Almeida-Porada, G.2    Colletti, E.J.3
  • 92
    • 0032477883 scopus 로고    scopus 로고
    • Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta
    • Pereira RF, O'Hara MD, Laptev AV et al. Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta. Proc Natl Acad Sci U S A 1998 95 : 1142 7.
    • (1998) Proc Natl Acad Sci U S a , vol.95 , pp. 1142-7
    • Pereira, R.F.1    O'Hara, M.D.2    Laptev, A.V.3
  • 93
    • 0028881201 scopus 로고
    • Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): Implications for therapeutic use
    • Lazarus HM, Haynesworth SE, Gerson SL, Rosenthal NS, Caplan AI. Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. Bone Marrow Transplant 1995 16 : 557 64.
    • (1995) Bone Marrow Transplant , vol.16 , pp. 557-64
    • Lazarus, H.M.1    Haynesworth, S.E.2    Gerson, S.L.3    Rosenthal, N.S.4    Caplan, A.I.5
  • 94
    • 0033977382 scopus 로고    scopus 로고
    • Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy
    • Koç ON, Gerson SL, Cooper BW et al. Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J Clin Oncol 2000 18 : 307 16.
    • (2000) J Clin Oncol , vol.18 , pp. 307-16
    • Koç, O.N.1    Gerson, S.L.2    Cooper, B.W.3
  • 95
    • 0032697409 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases
    • Koç ON, Peters C, Aubourg P et al. Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases. Exp Hematol 1999 27 : 1675 81.
    • (1999) Exp Hematol , vol.27 , pp. 1675-81
    • Koç, O.N.1    Peters, C.2    Aubourg, P.3
  • 96
    • 0021592719 scopus 로고
    • Transplantation in relation to the treatment of inherited disease
    • Groth CG, Ringden O. Transplantation in relation to the treatment of inherited disease. Transplantation 1984 38 : 319 27.
    • (1984) Transplantation , vol.38 , pp. 319-27
    • Groth, C.G.1    Ringden, O.2
  • 97
    • 0002406492 scopus 로고    scopus 로고
    • Bone marrow transplantation: Treatment for globoid cell leukodystrophy, metachromatic leukodystrophy, adrenoleukodystrophy and Hurler syndrome
    • In: Moser, H.W., Vinken, P.J., Bruyn, G.W., eds. Amsterdam: Elsevier Science
    • Krivit W, Shapiro EG, Lockman LA et al. Bone marrow transplantation: treatment for globoid cell leukodystrophy, metachromatic leukodystrophy, adrenoleukodystrophy and Hurler syndrome. In : Moser HW, Vinken PJ, Bruyn GW, eds. Handbook of Clinical Neurology. Amsterdam : Elsevier Science, 1996 : 87 106.
    • (1996) Handbook of Clinical Neurology. , pp. 87-106
    • Krivit, W.1    Shapiro, E.G.2    Lockman, L.A.3
  • 98
    • 0036676009 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH)
    • Koç ON, Day J, Nieder M, Gerson SL, Lazarus HM, Krivit W. Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH). Bone Marrow Transplant 2002 30 : 215 22.
    • (2002) Bone Marrow Transplant , vol.30 , pp. 215-22
    • Koç, O.N.1    Day, J.2    Nieder, M.3    Gerson, S.L.4    Lazarus, H.M.5    Krivit, W.6
  • 99
    • 0018577711 scopus 로고
    • Clinical variability in osteogenesis imperfecta-variable expressivity or genetic heterogeneity
    • Sillence DO, Rimoin DL, Danks DM. Clinical variability in osteogenesis imperfecta-variable expressivity or genetic heterogeneity. Birth Defects Orig Artic Ser 1979 15 : 113 29.
    • (1979) Birth Defects Orig Artic Ser , vol.15 , pp. 113-29
    • Sillence, D.O.1    Rimoin, D.L.2    Danks, D.M.3
  • 100
    • 0032976690 scopus 로고    scopus 로고
    • Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
    • Horwitz EM, Prockop DJ, Fitzpatrick LA et al. Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med 1999 5 : 309 13.
    • (1999) Nat Med , vol.5 , pp. 309-13
    • Horwitz, E.M.1    Prockop, D.J.2    Fitzpatrick, L.A.3
  • 101
    • 0035283077 scopus 로고    scopus 로고
    • Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta
    • Horwitz EM, Prockop DJ, Gordon PL et al. Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta. Blood 2001 97 : 1227 31.
    • (2001) Blood , vol.97 , pp. 1227-31
    • Horwitz, E.M.1    Prockop, D.J.2    Gordon, P.L.3
  • 102
    • 0037173116 scopus 로고    scopus 로고
    • Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone
    • Horwitz EM, Gordon PL, Koo WK et al. Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone. Proc Natl Acad Sci U S A 2002 99 : 8932 7.
    • (2002) Proc Natl Acad Sci U S a , vol.99 , pp. 8932-7
    • Horwitz, E.M.1    Gordon, P.L.2    Koo, W.K.3
  • 103
    • 0036050976 scopus 로고    scopus 로고
    • Treatment of high-risk acute myelogenous leukaemia by myeloablative chemoradiotherapy followed by co-infusion of T cell-depleted haematopoietic stem cells and culture-expanded marrow mesenchymal stem cells from a related donor with one fully mismatched human leucocyte antigen haplotype
    • Lee ST, Jang JH, Cheong JW et al. Treatment of high-risk acute myelogenous leukaemia by myeloablative chemoradiotherapy followed by co-infusion of T cell-depleted haematopoietic stem cells and culture-expanded marrow mesenchymal stem cells from a related donor with one fully mismatched human leucocyte antigen haplotype. Br J Haematol 2002 118 : 1128 31.
    • (2002) Br J Haematol , vol.118 , pp. 1128-31
    • Lee, S.T.1    Jang, J.H.2    Cheong, J.W.3
  • 104
    • 34447639255 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells
    • in press.
    • Le Blanc K, Gustafsson B, Remberger M et al. Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells. Leukemia 2007 in press.
    • (2007) Leukemia
    • Le Blanc, K.1    Gustafsson, B.2    Remberger, M.3
  • 105
    • 0035144015 scopus 로고    scopus 로고
    • Mesenchymal stem cells are capable of homing to the bone marrow of non- human primates following systemic infusion
    • Devine SM, Bartholomew AM, Mahmud N et al. Mesenchymal stem cells are capable of homing to the bone marrow of non- human primates following systemic infusion. Exp Hematol 2001 29 : 244 55.
    • (2001) Exp Hematol , vol.29 , pp. 244-55
    • Devine, S.M.1    Bartholomew, A.M.2    Mahmud, N.3
  • 106
    • 20244389227 scopus 로고    scopus 로고
    • Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients
    • Lazarus HM, Koc ON, Devine SM et al. Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients. Biol Blood Marrow Transplant 2005 11 : 389 98.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 389-98
    • Lazarus, H.M.1    Koc, O.N.2    Devine, S.M.3
  • 107
    • 4644251301 scopus 로고    scopus 로고
    • Replacement of recipient stromal/mesenchymal cells after bone marrow transplantation using bone fragments and cultured osteoblast-like cells
    • Cahill RA, Jones OY, Klemperer M et al. Replacement of recipient stromal/mesenchymal cells after bone marrow transplantation using bone fragments and cultured osteoblast-like cells. Biol Blood Marrow Transplant 2004 10 : 709 17.
    • (2004) Biol Blood Marrow Transplant , vol.10 , pp. 709-17
    • Cahill, R.A.1    Jones, O.Y.2    Klemperer, M.3
  • 108
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004 363 : 1439 41.
    • (2004) Lancet , vol.363 , pp. 1439-41
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 109
    • 33744913533 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease
    • Ringdén O, Uzunel M, Rasmusson I et al. Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation 2006 81 : 1390 7.
    • (2006) Transplantation , vol.81 , pp. 1390-7
    • Ringdén, O.1    Uzunel, M.2    Rasmusson, I.3
  • 110
    • 35448947816 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of severe graft-versus-host disease
    • Le Blanc K, Frassoni F, Uzunel M et al. Mesenchymal stem cells for treatment of severe graft-versus-host disease. Blood 2006 108 : 753a.
    • (2006) Blood , vol.108
    • Le Blanc, K.1    Frassoni, F.2    Uzunel, M.3
  • 111
    • 35449007194 scopus 로고    scopus 로고
    • Tissue repair using allogeneic mesenchymal stem cells for hemorrhagic cystitis, pneumomediastinum and perforated colon
    • in press.
    • Ringdén O, Uzunel M, Sundberg B et al. Tissue repair using allogeneic mesenchymal stem cells for hemorrhagic cystitis, pneumomediastinum and perforated colon. Leukaemia 2007 in press.
    • (2007) Leukaemia
    • Ringdén, O.1    Uzunel, M.2    Sundberg, B.3
  • 112
    • 33646759606 scopus 로고    scopus 로고
    • Mesenchymal stem cells are susceptible to human herpesviruses, but viral DNA cannot be detected in the healthy seropositive individual
    • Sundin M, Orvell C, Rasmusson I, Sundberg B, Ringden O, Le Blanc K. Mesenchymal stem cells are susceptible to human herpesviruses, but viral DNA cannot be detected in the healthy seropositive individual. Bone Marrow Transplant 2006 37 : 1051 9.
    • (2006) Bone Marrow Transplant , vol.37 , pp. 1051-9
    • Sundin, M.1    Orvell, C.2    Rasmusson, I.3    Sundberg, B.4    Ringden, O.5    Le Blanc, K.6
  • 113
    • 0025100777 scopus 로고
    • Graft-versus-leukemia reactions after bone marrow transplantation
    • Horowitz MM, Gale RP, Sondel PM et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood 1990 75 : 555 62.
    • (1990) Blood , vol.75 , pp. 555-62
    • Horowitz, M.M.1    Gale, R.P.2    Sondel, P.M.3
  • 114
    • 0018764352 scopus 로고
    • Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts
    • Weiden PL, Flournoy N, Thomas ED et al. Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts. N Engl J Med 1979 300 : 1068 73.
    • (1979) N Engl J Med , vol.300 , pp. 1068-73
    • Weiden, P.L.1    Flournoy, N.2    Thomas, E.D.3
  • 115
    • 0345206680 scopus 로고    scopus 로고
    • Graft-versus-leukemia effect in allogeneic marrow transplant recipients with acute leukemia is maintained using cyclosporin a combined with methotrexate as prophylaxis. Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation
    • Ringden O, Labopin M, Gluckman E et al. Graft-versus-leukemia effect in allogeneic marrow transplant recipients with acute leukemia is maintained using cyclosporin A combined with methotrexate as prophylaxis. Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 1996 18 : 921 9.
    • (1996) Bone Marrow Transplant , vol.18 , pp. 921-9
    • Ringden, O.1    Labopin, M.2    Gluckman, E.3
  • 116
    • 0030454494 scopus 로고    scopus 로고
    • The highest leukaemia-free survival after allogeneic bone marrow transplantation is seen in patients with grade I acute graft-versus-host disease. Acute and Chronic Leukaemia Working Parties of the European Group for Blood and Marrow Transplantation (EBMT)
    • Ringden O, Hermans J, Labopin M, Apperley J, Gorin NC, Gratwohl A. The highest leukaemia-free survival after allogeneic bone marrow transplantation is seen in patients with grade I acute graft-versus-host disease. Acute and Chronic Leukaemia Working Parties of the European Group for Blood and Marrow Transplantation (EBMT). Leuk Lymphoma 1996 24 : 71 9.
    • (1996) Leuk Lymphoma , vol.24 , pp. 71-9
    • Ringden, O.1    Hermans, J.2    Labopin, M.3    Apperley, J.4    Gorin, N.C.5    Gratwohl, A.6
  • 117
    • 0037443911 scopus 로고    scopus 로고
    • Migration of mesenchymal stem cells to heart allografts during chronic rejection
    • Wu GD, Nolta JA, Jin YS et al. Migration of mesenchymal stem cells to heart allografts during chronic rejection. Transplantation 2003 75 : 679 85.
    • (2003) Transplantation , vol.75 , pp. 679-85
    • Wu, G.D.1    Nolta, J.A.2    Jin, Y.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.