Substance P promotes expansion of human mesenteric preadipocytes through proliferative and antiapoptotic pathways

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 296, Issue 5, 2009, Pages

  Gross, Kara ^a,c   Karagiannides, Iordanes ^a,b   Thomou, Thomas ^d   Hon, Wai Koon ^a,b   Bowe, Collin ^a,b   Kim, Ho ^a,b   Giorgadze, Nino ^d   Tchkonia, Tamara ^d   Pirtskhalava, Tamara ^d   Kirkland, James L ^d   Pothoulakis, Charalabos ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NewYork Presbyterian Hospital   (United States)

^d MAYO CLINIC   (United States)

Author keywords

Adipocyte; Akt; Creeping fat; Crohn's disease; Neuropeptide; Proliferation; Protein kinase C

Indexed keywords

CASPASE 3; CASPASE 7; EPIDERMAL GROWTH FACTOR RECEPTOR; INITIATION FACTOR 4E BINDING PROTEIN 1; NEUROKININ 1 RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C THETA; S6 KINASE; SOMATOMEDIN RECEPTOR; SUBSTANCE P; VITRONECTIN RECEPTOR; CASP3 PROTEIN, HUMAN; CASP7 PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; EIF4EBP1 PROTEIN, HUMAN; FAS LIGAND; ISOENZYME; PHOSPHOPROTEIN; PRKCQ PROTEIN, HUMAN; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SOMATOMEDIN C RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; HUMAN; HUMAN CELL; INFLAMMATION; MESENTERY; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; ADIPOCYTE; CELL CULTURE; CELL CYCLE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; INTRAABDOMINAL FAT; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADIPOCYTES; APOPTOSIS; CASPASE 3; CASPASE 7; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; FAS LIGAND PROTEIN; HUMANS; INTEGRIN ALPHAVBETA3; INTRA-ABDOMINAL FAT; ISOENZYMES; PHOSPHOPROTEINS; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, IGF TYPE 1; RECEPTORS, NEUROKININ-1; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; SUBSTANCE P; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 66149105495     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90351.2008     Document Type: Article

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