Myeloid cells in the tumor microenvironment: Modulation of tumor angiogenesis and tumor inflammation

Journal of Oncology

Volumn , Issue , 2010, Pages

  Varner, Judith A ^a   Schmid, Michael C ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN RECEPTOR; ANTINEOPLASTIC AGENT; ARGINASE; BASIC FIBROBLAST GROWTH FACTOR; BETA DEFENSIN; BV8 ANTIBODY; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 8; METALLOPROTEINASE; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; PLACENTAL GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; STROMAL CELL DERIVED FACTOR 1BETA; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN ANTIBODY; VASCULOTROPIN RECEPTOR 2;

BONE MARROW CELL; CANCER RESISTANCE; CELL FUNCTION; CELL HETEROGENEITY; CELL SUBPOPULATION; CELLULAR IMMUNITY; DENDRITIC CELL; DRUG MECHANISM; EOSINOPHIL COUNT; HUMAN; IMMUNE DEFICIENCY; IMMUNOMODULATION; IMMUNOPHENOTYPING; IMMUNOSTIMULATION; LYMPHOCYTE ACTIVATION; MACROPHAGE MIGRATION; MAST CELL; MONOCYTE; NEUTROPHIL COUNT; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SUPPRESSOR CELL; TUMOR ASSOCIATED LEUKOCYTE; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

EID: 77953487609     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2010/201026     Document Type: Review

References (101)

1. Carmeliet P., Angiogenesis in life, disease and medicine Nature 2005 438 7070 932 936
2. Coussens L. M., Werb Z., Inflammation and cancer Nature 2002 420 6917 860 867
3. Folkman J., Tumor angiogenesis: therapeutic implications The New England Journal of Medicine 1971 285 21 1182 1186
4. Hanahan D., Folkman J., Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 1996 86 3 353 364
5. Kerbel R. S., Tumor angiogenesis The New England Journal of Medicine 2008 358 19 2039 2049
6. Folkman J., Merler E., Abernathy C., Williams G., Isolation of a tumor factor responsible or angiogenesis Journal of Experimental Medicine 1971 133 2 275 288
7. Carmeliet P., Jain R. K., Angiogenesis in cancer and other diseases Nature 2000 407 6801 249 257
8. Shojaei F., Wu X., Zhong C., Bv8 regulates myeloid-cell-dependent tumour angiogenesis Nature 2007 450 7171 825 831
9. Du R., Lu K. V., Petritsch C., HIF1 induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion Cancer Cell 2008 13 3 206 220
10. DeNardo D. G., Barreto J. B., Andreu P., CD 4 + T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages Cancer Cell 2009 16 2 91 102
11. Fridlender Z. G., Sun J., Kim S., Polarization of tumor-associated neutrophil phenotype by TGF- : N1 versus N2 TAN Cancer Cell 2009 16 3 183 194
12. Schmid M. C., Varner J. A., Myeloid cell trafficking and tumor angiogenesis Cancer Letters 2007 250 1 1 8
13. Asahara T., Murohara T., Sullivan A., Isolation of putative progenitor endothelial cells for angiogenesis Science 1997 275 5302 964 967
14. Peichev M., Naiyer A. J., Pereira D., Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors Blood 2000 95 3 952 958
15. Gill M., Dias S., Hattori K., Vascular trauma induces rapid but transient mobilization of VEGFR2+ AC133+ endothelial precursor cells Circulation Research 2001 88 2 167 174
16. Gao D., Nolan D., McDonnell K., Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression Biochimica et Biophysica Acta 2009 1796 1 33 40
17. Gao D., Nolan D. J., Mellick A. S., Bambino K., McDonnell K., Mittal V., Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis Science 2008 319 5860 195 198
18. Garcia-Barros M., Paris F., Cordon-Cardo C., Tumor response to radiotherapy regulated by endothelial cell apoptosis Science 2003 300 5622 1155 1159
19. Spring H., Schuler T., Arnold B., Hammerling G. J., Ganss R., Chemokines direct endothelial progenitors into tumor neovessels Proceedings of the National Academy of Sciences of the United States of America 2005 102 50 18111 18116
20. Peters B. A., Diaz L. A. Jr., Polyak K., Contribution of bone marrow-derived endothelial cells to human tumor vasculature Nature Medicine 2005 11 3 261 262
21. Mantovani A., Sozzani S., Locati M., Allavena P., Sica A., Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes Trends in Immunology 2002 23 11 549 555
22. Mantovani A., Schioppa T., Porta C., Allavena P., Sica A., Role of tumor-associated macrophages in tumor progression and invasion Cancer and Metastasis Reviews 2006 25 3 315 322
23. Martinez F. O., Helming L., Gordon S., Alternative activation of macrophages: an immunologic functional perspective Annual Review of Immunology 2009 27 451 483
24. Martinez F. O., Sica A., Mantovani A., Locati M., Macrophage activation and polarization Frontiers in Bioscience 2008 13 2 453 461
25. Biswas S. K., Sica A., Lewis C. E., Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms Journal of Immunology 2008 180 4 2011 2017
26. Lewis J. S., Landers R. J., Underwood J. C. E., Harris A. L., Lewis C. E., Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas Journal of Pathology 2000 192 2 150 158
27. Sunderkotter C., Steinbrink K., Goebeler M., Bhardwaj R., Sorg C., Macrophages and angiogenesis Journal of Leukocyte Biology 1994 55 3 410 422
28. Giraudo E., Inoue M., Hanahan D., An amino-bisphosphonate targets MMP-9expressing macrophages and angiogenesis to impair cervical carcinogenesis Journal of Clinical Investigation 2004 114 5 623 633
29. Hildenbrand R., Dilger I., Horlin A., Stutte H. J., Urokinase and macrophages in tumour angiogenesis British Journal of Cancer 1995 72 4 818 823
30. Balkwill F., Mantovani A., Inflammation and cancer: back to Virchow? The Lancet 2001 357 9255 539 545
31. Huang S., Van Arsdall M., Tedjarati S., Contributions of stromal metalloproteinase-9 to angiogenesis and growth of human ovarian carcinoma in mice Journal of the National Cancer Institute 2002 94 15 1134 1142
32. Esposito I., Menicagli M., Funel N., Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma Journal of Clinical Pathology 2004 57 6 630 636
33. Polverini P. J., Leibovich S. J., Effect of macrophage depletion on growth and neovascularization of hamster buccal pouch carcinomas Journal of Oral Pathology 1987 16 9 436 441
34. Leek R. D., Harris A. L., Tumor-associated macrophages in breast cancer Journal of Mammary Gland Biology and Neoplasia 2002 7 2 177 189
35. Nishie A., Ono M., Shono T., Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas Clinical Cancer Research 1999 5 5 1107 1113
36. Gabrilovich D. I., Nagaraj S., Myeloid-derived suppressor cells as regulators of the immune system Nature Reviews Immunology 2009 9 3 162 174
37. Yang R., Cai Z., Zhang Y., Yutzy W. H. IV, Roby K. F., Roden R. B. S., CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cells Cancer Research 2006 66 13 6807 6815
38. Gallina G., Dolcetti L., Serafini P., Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells Journal of Clinical Investigation 2006 116 10 2777 2790
39. Youn J.-I., Nagaraj S., Collazo M., Gabrilovich D. I., Subsets of myeloid-derived suppressor cells in tumor-bearing mice Journal of Immunology 2008 181 8 5791 5802
40. Sawanobori Y., Ueha S., Kurachi M., Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice Blood 2008 111 12 5457 5466
41. Ochoa A. C., Zea A. H., Hernandez C., Rodriguez P. C., Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma Clinical Cancer Research 2007 13 2 721s 725s
42. Almand B., Clark J. I., Nikitina E., Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer Journal of Immunology 2001 166 1 678 689
43. Schmielau J., Finn O. J., Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients Cancer Research 2001 61 12 4756 4760
44. Kusmartsev S., Gabrilovich D. I., Role of immature myeloid cells in mechanisms of immune evasion in cancer Cancer Immunology, Immunotherapy 2006 55 3 237 245
45. Rodriguez P. C., Ernstoff M. S., Hernandez C., Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes Cancer Research 2009 69 4 1553 1560
46. Nagaraj S., Gupta K., Pisarev V., Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer Nature Medicine 2007 13 7 828 835
47. Sauer H., Wartenberg M., Hescheler J., Reactive oxygen species as intracellular messengers during cell growth and differentiation Cellular Physiology and Biochemistry 2001 11 4 173 186
48. Taketo M. M., Cyclooxygenase-2 inhibitors in tumorigenesis (part I) Journal of the National Cancer Institute 1998 90 20 1529 1536
49. Bertagnolli M. M., Chemoprevention of colorectal cancer with cyclooxygenase-2 inhibitors: two steps forward, one step back The Lancet Oncology 2007 8 5 439 443
50. Ostrand-Rosenberg S., Sinha P., Myeloid-derived suppressor cells: linking inflammation and cancer Journal of Immunology 2009 182 8 4499 4506
51. Fichtner-Feigl S., Terabe M., Kitani A., Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor- 2 Cancer Research 2008 68 9 3467 3475
52. Terabe M., Matsui S., Park J.-M., Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence Journal of Experimental Medicine 2003 198 11 1741 1752
53. De Palma M., Venneri M. A., Galli R., Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors Cancer Cell 2005 8 3 211 226
54. De Palma M., Venneri M. A., Naldini L., In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors Human Gene Therapy 2003 14 12 1193 1206
55. De Palma M., Naldini L., Tie2-expressing monocytes (TEMs): novel targets and vehicles of anticancer therapy? Biochimica et Biophysica Acta 2009 1796 1 5 10
56. Eck M., Schmausser B., Scheller K., Brandlein S., Muller-Hermelink H. K., Pleiotropic effects of CXC chemokines in gastric carcinoma: differences in CXCL8 and CXCL1 expression between diffuse and intestinal types of gastric carcinoma Clinical and Experimental Immunology 2003 134 3 508 515
57. Bellocq A., Antoine M., Flahault A., Neutrophil alveolitis in bronchioloalveolar carcinoma: induction by tumor-derived interleukin-8 and relation to clinical outcome American Journal of Pathology 1998 152 1 83 92
58. Bergers G., Brekken R., McMahon G., Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis Nature Cell Biology 2000 2 10 737 744
59. McCourt M., Wang J. H., Sookhai S., Redmond H. P., Proinflammatory mediators stimulate neutrophil-directed angiogenesis Archives of Surgery 1999 134 12 1325 1332
60. Rothenberg M. E., Hogan S. P., The eosinophil Annual Review of Immunology 2006 24 147 174
61. Dorta R. G., Landman G., Kowalski L. P., Lauris J. R. P., Latorre M. R., Oliveira D. T., Tumour-associated tissue eosinophilia as a prognostic factor in oral squamous cell carcinomas Histopathology 2002 41 2 152 157
62. Looi L.-M., Tumor-associated tissue eosinophilia in nasopharyngeal carcinoma. A pathologic study of 422 primary and 138 metastatic tumors Cancer 1987 59 3 466 470
63. Teruya-Feldstein J., Jaffe E. S., Burd P. R., Kingma D. W., Setsuda J. E., Tosato G., Differential chemokine expression in tissues involved by Hodgkin's disease: direct correlation of eotaxin expression and tissue eosinophilia Blood 1999 93 8 2463 2470
64. Nielsen H. J., Hansen U., Christensen I. J., Reimert C. M., Brunner N., Moesgaard F., Independent prognostic value of eosinophil and mast cell infiltration in colorectal cancer tissue Journal of Pathology 1999 189 4 487 495
65. Lorena S. C. M., Oliveira D. T., Dorta R. G., Landman G., Kowalski L. P., Eotaxin expression in oral squamous cell carcinomas with and without tumour associated tissue eosinophilia Oral Diseases 2003 9 6 279 283
66. Mattes J., Hulett M., Xie W., Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process Journal of Experimental Medicine 2003 197 3 387 393
67. Horiuchi T., Weller P. F., Expression of vascular endothelial growth factor by human eosinophils: upregulation by granulocyte macrophage colony-stimulating factor and interleukin-5 American Journal of Respiratory Cell and Molecular Biology 1997 17 1 70 77
68. Cormier S. A., Taranova A. G., Bedient C., Pivotal advance: eosinophil infiltration of solid tumors is an early and persistent inflammatory host response Journal of Leukocyte Biology 2006 79 6 1131 1139
69. Ribatti D., Crivellato E., The controversial role of mast cells in tumor growth International Review of Cell and Molecular Biology 2009 275 89 131
70. Crivellato E., Nico B., Ribatti D., Mast cells and tumour angiogenesis: new insight from experimental carcinogenesis Cancer Letters 2008 269 1 1 6
71. Colonna M., Trinchieri G., Liu Y.-J., Plasmacytoid dendritic cells in immunity Nature Immunology 2004 5 12 1219 1226
72. Gottfried E., Kreutz M., Mackensen A., Tumor-induced modulation of dendritic cell function Cytokine and Growth Factor Reviews 2008 19 1 65 77
73. Fricke I., Gabrilovich D. I., Dendritic cells and tumor microenvironment: a dangerous liaison Immunological Investigations 2006 35 3-4 459 483
74. Conejo-Garcia J. R., Benencia F., Courreges M.-C., Tumor-infiltrating dendritic cell precursors recruited by a -defensin contribute to vasculogenesis under the influence of Vegf-A Nature Medicine 2004 10 9 950 958
75. Coukos G., Conejo-Garcia J. R., Buckanovich R., Benencia F., Vascular leukocytes: a population with angiogenic and immunossuppressive properties highly represented in ovarian cancer Advances in Experimental Medicine and Biology 2007 590 185 193
76. Fainaru O., Almog N., Yung C. W., Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells The FASEB Journal 2010 24 5 1411 1418
77. Ricciardi A., Elia A. R., Cappello P., Transcriptome of hypoxic immature dendritic cells: modulation of chemokine/receptor expression Molecular Cancer Research 2008 6 2 175 185
78. Shojaei F., Wu X., Malik A. K., Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells Nature Biotechnology 2007 25 8 911 920
79. Fischer C., Jonckx B., Mazzone M., Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels Cell 2007 131 3 463 475
80. Weber C., Koenen R. R., Fine-tuning leukocyte responses: towards a chemokine interactome Trends in Immunology 2006 27 6 268 273
81. Luster A. D., Alon R., von Andrian U. H., Immune cell migration in inflammation: present and future therapeutic targets Nature Immunology 2005 6 12 1182 1190
82. Giaccia A. J., Simon M. C., Johnson R., The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease Genes and Development 2004 18 18 2183 2194
83. Liao D., Johnson R. S., Hypoxia: a key regulator of angiogenesis in cancer Cancer and Metastasis Reviews 2007 26 2 281 290
84. Ueno T., Toi M., Saji H., Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer Clinical Cancer Research 2000 6 8 3282 3289
85. Niwa Y., Akamatsu H., Niwa H., Sumi H., Ozaki Y., Abe A., Correlation of tissue and plasma RANTES levels with disease course in patients with breast or cervical cancer Clinical Cancer Research 2001 7 2 285 289
86. Lin E. Y., Nguyen A. V., Russell R. G., Pollard J. W., Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy Journal of Experimental Medicine 2001 193 6 727 739
87. Murdoch C., Giannoudis A., Lewis C. E., Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues Blood 2004 104 8 2224 2234
88. Zhu Y. M., Webster S. J., Flower D., Woll P. J., Interleukin-8/CXCL8 is a growth factor for human lung cancer cells British Journal of Cancer 2004 91 11 1970 1976
89. Uutela M., Wirzenius M., Paavonen K., PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis Blood 2004 104 10 3198 3204
90. Barleon B., Sozzani S., Zhou D., Weich H. A., Mantovani A., Marme D., Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1 Blood 1996 87 8 3336 3343
91. Goswami S., Sahai E., Wyckoff J. B., Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop Cancer Research 2005 65 12 5278 5283
92. Nakao S., Kuwano T., Tsutsumi-Miyahara C., Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 -induced neovascularization and tumor growth Journal of Clinical Investigation 2005 115 11 2979 2991
93. Jin D. K., Shido K., Kopp H.-G., Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR 4+ hemangiocytes Nature Medicine 2006 12 5 557 567
94. LeCouter J., Kowalski J., Foster J., Identification of an angiogenic mitogen selective for endocrine gland endothelium Nature 2001 412 6850 877 884
95. LeCouter J., Zlot C., Tejada M., Peale F., Ferrara N., Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization Proceedings of the National Academy of Sciences of the United States of America 2004 101 48 16813 16818
96. Shojaei F., Wu X., Qu X., G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models Proceedings of the National Academy of Sciences of the United States of America 2009 106 16 6742 6747
97. Yang L., Huang J., Ren X., Abrogation of TGF signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis Cancer Cell 2008 13 1 23 35
98. Stark G. R., Kerr I. M., Williams B. R. G., Silverman R. H., Schreiber R. D., How cells respond to interferons Annual Review of Biochemistry 1998 67 227 264
99. De Palma M., Mazzieri R., Politi L. S., Tumor-targeted interferon- delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis Cancer Cell 2008 14 4 299 311
100. Aboody K. S., Najbauer J., Danks M. K., Stem and progenitor cell-mediated tumor selective gene therapy Gene Therapy 2008 15 10 739 752
101. Ferrara N., Kerbel R. S., Angiogenesis as a therapeutic target Nature 2005 438 7070 967 974