메뉴 건너뛰기




Volumn 161, Issue 1, 2010, Pages 10-18

T cell responses induced by allergen-specific immunotherapy

Author keywords

Allergen specific immunotherapy; Allergy; Cytokines; Regulatory T cells; T effector cells

Indexed keywords

ALLERGEN; BEE VENOM; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HYMENOPTERA VENOM; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 35; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 9; MESSENGER RNA; POLLEN ANTIGEN; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

EID: 77953246494     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2010.04148.x     Document Type: Review
Times cited : (64)

References (99)
  • 1
    • 0026443490 scopus 로고
    • Immunotherapy with allergens
    • Creticos PS. Immunotherapy with allergens. JAMA 1992 268 : 2834 2839.
    • (1992) JAMA , vol.268 , pp. 2834-2839
    • Creticos, P.S.1
  • 2
    • 0027214706 scopus 로고
    • EAACI position paper: Immunotherapy
    • Malling H-J, Weeke B. EAACI position paper: immunotherapy. Allergy 1993 48 : 9 35.
    • (1993) Allergy , vol.48 , pp. 9-35
    • Malling, H.-J.1    Weeke, B.2
  • 3
    • 2442648797 scopus 로고    scopus 로고
    • Allergen immunotherapy: Therapeutic vaccines for allergic diseases. World Health Organization. American Academy of Allergy, Asthma and Immunology
    • Bousquet J, Lockey R, Malling HJ et al. Allergen immunotherapy: Therapeutic vaccines for allergic diseases. World Health Organization. American Academy of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol 1998 81 : 401 405.
    • (1998) Ann Allergy Asthma Immunol , vol.81 , pp. 401-405
    • Bousquet, J.1    Lockey, R.2    Malling, H.J.3
  • 4
    • 0033549827 scopus 로고    scopus 로고
    • Long-term clinical efficacy of grass-pollen immunotherapy
    • Durham SR, Walker SM, Varga EM et al. Long-term clinical efficacy of grass-pollen immunotherapy. N Engl J Med 1999 341 : 468 475.
    • (1999) N Engl J Med , vol.341 , pp. 468-475
    • Durham, S.R.1    Walker, S.M.2    Varga, E.M.3
  • 5
    • 33644900473 scopus 로고    scopus 로고
    • Twelve-year follow-up after discontinuation of preseasonal grass pollen immunotherapy in childhood
    • Eng PA, Borer-Reinhold M, Heijnen IA, Gnehm HP. Twelve-year follow-up after discontinuation of preseasonal grass pollen immunotherapy in childhood. Allergy 2006 61 : 198 201.
    • (2006) Allergy , vol.61 , pp. 198-201
    • Eng, P.A.1    Borer-Reinhold, M.2    Heijnen, I.A.3    Gnehm, H.P.4
  • 6
    • 0032707795 scopus 로고    scopus 로고
    • Grass pollen immunotherapy decreases the number of mast cells in the skin
    • Durham SR, Varney VA, Gaga M et al. Grass pollen immunotherapy decreases the number of mast cells in the skin. Clin Exp Allergy 1999 29 : 1490 1496.
    • (1999) Clin Exp Allergy , vol.29 , pp. 1490-1496
    • Durham, S.R.1    Varney, V.A.2    Gaga, M.3
  • 7
    • 0027222095 scopus 로고
    • Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
    • Varney VA, Hamid QA, Gaga M et al. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 1993 92 : 644 651.
    • (1993) J Clin Invest , vol.92 , pp. 644-651
    • Varney, V.A.1    Hamid, Q.A.2    Gaga, M.3
  • 8
    • 0028214659 scopus 로고
    • The effect of immunotherapy on the cutaneous late phase response to antigen
    • Nish WA, Charlesworth EN, Davis TL et al. The effect of immunotherapy on the cutaneous late phase response to antigen. J Allergy Clin Immunol 1994 93 : 484 493.
    • (1994) J Allergy Clin Immunol , vol.93 , pp. 484-493
    • Nish, W.A.1    Charlesworth, E.N.2    Davis, T.L.3
  • 11
    • 12444291506 scopus 로고    scopus 로고
    • Sublingual immunotherapy for allergic rhinitis: Systematic review and meta-analysis
    • Wilson DR, Lima MT, Durham SR. Sublingual immunotherapy for allergic rhinitis: Systematic review and meta-analysis. Allergy 2005 60 : 4 12.
    • (2005) Allergy , vol.60 , pp. 4-12
    • Wilson, D.R.1    Lima, M.T.2    Durham, S.R.3
  • 12
    • 63449096386 scopus 로고    scopus 로고
    • Sublingual immunotherapy for allergic rhinitis: An updated Cochrane systematic review and meta-analysis
    • Radulovic C, Calderon M, Wilson S, Durham SR. Sublingual immunotherapy for allergic rhinitis: An updated Cochrane systematic review and meta-analysis. Allergy 2007 62 (s83 167 171.
    • (2007) Allergy , vol.6283 , pp. 167-171
    • Radulovic, C.1    Calderon, M.2    Wilson, S.3    Durham, S.R.4
  • 13
    • 33748289993 scopus 로고    scopus 로고
    • Efficacy of sublingual immunotherapy in asthma: Systematic review of randomized clinical trials using the Cochrane Collaboration Method
    • Calamita Z, Saconato H, Pela AB, Atallah AN. Efficacy of sublingual immunotherapy in asthma: Systematic review of randomized clinical trials using the Cochrane Collaboration Method. Allergy 2006 61 : 1162 1172.
    • (2006) Allergy , vol.61 , pp. 1162-1172
    • Calamita, Z.1    Saconato, H.2    Pela, A.B.3    Atallah, A.N.4
  • 14
    • 40549140165 scopus 로고    scopus 로고
    • Meta-analysis of the efficacy of sublingual immunotherapy in the treatment of allergic asthma in pediatric patients, 3-18 years of age
    • Penagos M, Passalacqua G, Campalati E et al. Meta-analysis of the efficacy of sublingual immunotherapy in the treatment of allergic asthma in pediatric patients, 3-18 years of age. Chest 2008 133 : 599 609.
    • (2008) Chest , vol.133 , pp. 599-609
    • Penagos, M.1    Passalacqua, G.2    Campalati, E.3
  • 15
    • 67650713944 scopus 로고    scopus 로고
    • Immunomodulation of allergic disease
    • Broide DH. Immunomodulation of allergic disease. Annu Rev Med 2009 60 : 279 291.
    • (2009) Annu Rev Med , vol.60 , pp. 279-291
    • Broide, D.H.1
  • 18
    • 67649220642 scopus 로고    scopus 로고
    • Sublingual immunotherapy for allergic respiratory diseases: An evaluation of meta-analyses
    • Nieto A, Mazon A, Pamies R, Bruno L, Navarro M, Montanes A. Sublingual immunotherapy for allergic respiratory diseases: An evaluation of meta-analyses. J Allergy Clin Immunol 2009 124 : 157 161.
    • (2009) J Allergy Clin Immunol , vol.124 , pp. 157-161
    • Nieto, A.1    Mazon, A.2    Pamies, R.3    Bruno, L.4    Navarro, M.5    Montanes, A.6
  • 19
    • 41149092695 scopus 로고    scopus 로고
    • Immunotherapy in children and adolescents with allergic rhinoconjunctivitis: A systematic review
    • Röder E, Berger MY, de Groot H, van Wijk RG. Immunotherapy in children and adolescents with allergic rhinoconjunctivitis: A systematic review. Pediatr Allergy Immunol 2008 19 : 197 207.
    • (2008) Pediatr Allergy Immunol , vol.19 , pp. 197-207
    • Röder, E.1    Berger, M.Y.2    De Groot, H.3    Van Wijk, R.G.4
  • 20
    • 70349852928 scopus 로고    scopus 로고
    • The efficacy of sublingual immunotherapy for house dust mites respiratory allergy: Results of a GA(2)LEN meta-analysis
    • Compalati E, Passalacqua G, Bonini M, Canonica GW. The efficacy of sublingual immunotherapy for house dust mites respiratory allergy: results of a GA(2)LEN meta-analysis. Allergy 2009 64 : 1570 1579.
    • (2009) Allergy , vol.64 , pp. 1570-1579
    • Compalati, E.1    Passalacqua, G.2    Bonini, M.3    Canonica, G.W.4
  • 21
    • 0034065298 scopus 로고    scopus 로고
    • The role of lymphocytes in allergic disease
    • Romagnani S. The role of lymphocytes in allergic disease. J Allergy Clin Immunol 2000 105 : 399 408.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 399-408
    • Romagnani, S.1
  • 22
    • 0037338904 scopus 로고    scopus 로고
    • The role of T lymphocytes in the pathogenesis of asthma
    • Larché M, Robinson DS, Kay AB. The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol 2003 111 : 450 464.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 450-464
    • Larché, M.1    Robinson, D.S.2    Kay, A.B.3
  • 23
    • 40049100646 scopus 로고    scopus 로고
    • Discovering susceptibility genes for asthma and allergy
    • Vercelli D. Discovering susceptibility genes for asthma and allergy. Nat Rev Immunol 2008 8 : 169 182.
    • (2008) Nat Rev Immunol , vol.8 , pp. 169-182
    • Vercelli, D.1
  • 24
    • 40049088465 scopus 로고    scopus 로고
    • Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma
    • DOI 10.1038/nri2275, PII NRI2275
    • Hammad H, Lambrecht BN. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat Rev Immunol 2008 8 : 193 204. (Pubitemid 351323293)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.3 , pp. 193-204
    • Hammad, H.1    Lambrecht, B.N.2
  • 25
    • 7044260315 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung
    • Lee CG, Link H, Baluk P et al. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nat Med 2004 10 : 1095 1103.
    • (2004) Nat Med , vol.10 , pp. 1095-1103
    • Lee, C.G.1    Link, H.2    Baluk, P.3
  • 26
    • 59049100417 scopus 로고    scopus 로고
    • Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein
    • Trompette A, Divanovic S, Visintin A et al. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 457 : 585 588.
    • (2009) Nature , vol.457 , pp. 585-588
    • Trompette, A.1    Divanovic, S.2    Visintin, A.3
  • 27
    • 71849086031 scopus 로고    scopus 로고
    • Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis
    • Murugaiyan G, Mittal A, Weiner HL. Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis. J Immunol 2008 181 : 7480 7488.
    • (2008) J Immunol , vol.181 , pp. 7480-7488
    • Murugaiyan, G.1    Mittal, A.2    Weiner, H.L.3
  • 28
    • 34547734621 scopus 로고    scopus 로고
    • Phenotypic and functional features of human Th17 cells
    • Annunziato F, Cosmi L, Santarlasci V et al. Phenotypic and functional features of human Th17 cells. J Exp Med 2007 204 : 1849 1861.
    • (2007) J Exp Med , vol.204 , pp. 1849-1861
    • Annunziato, F.1    Cosmi, L.2    Santarlasci, V.3
  • 29
    • 49249135394 scopus 로고    scopus 로고
    • Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor
    • Cosmi L, De Palma R, Santarlasci V et al. Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J Exp Med 2008 205 : 1903 1916.
    • (2008) J Exp Med , vol.205 , pp. 1903-1916
    • Cosmi, L.1    De Palma, R.2    Santarlasci, V.3
  • 30
    • 33748515008 scopus 로고    scopus 로고
    • IL-17A induces eotaxin-1/CC chemokine ligand 11 expression in human airway smooth muscle cells: Role of MAPK (Erk1/2, JNK, and p38) pathways
    • Rahman MS, Yamasaki A, Yang J, Shan L, Halayko AJ, Gounni AS. IL-17A induces eotaxin-1/CC chemokine ligand 11 expression in human airway smooth muscle cells: role of MAPK (Erk1/2, JNK, and p38) pathways. J Immunol 2006 177 : 4046 4071.
    • (2006) J Immunol , vol.177 , pp. 4046-4071
    • Rahman, M.S.1    Yamasaki, A.2    Yang, J.3    Shan, L.4    Halayko, A.J.5    Gounni, A.S.6
  • 32
    • 73149118287 scopus 로고    scopus 로고
    • Demonstration of a small subset of human circulating memory CD161+ CD4+ T cells that produce both IL-17A and IL-4
    • Cosmi L, Maggi L, Santarlasci V et al. Demonstration of a small subset of human circulating memory CD161+ CD4+ T cells that produce both IL-17A and IL-4. J Allergy Clin Immunol 2010 125 : 222 230.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 222-230
    • Cosmi, L.1    Maggi, L.2    Santarlasci, V.3
  • 33
    • 65349119355 scopus 로고    scopus 로고
    • Development and function of TH17 cells in health and disease
    • Louten J, Boniface K, Malefyt R. Development and function of TH17 cells in health and disease. J Allergy Clin Immunol 2009 123 : 1004 1011.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 1004-1011
    • Louten, J.1    Boniface, K.2    Malefyt, R.3
  • 34
    • 0032401770 scopus 로고    scopus 로고
    • Immunotherapy of allergy: Anergy, deletion, and immune deviation
    • Rolland J, O'Hehir R. Immunotherapy of allergy: Anergy, deletion, and immune deviation. Curr Opin Immunol 1998 10 : 640 645.
    • (1998) Curr Opin Immunol , vol.10 , pp. 640-645
    • Rolland, J.1    O'Hehir, R.2
  • 35
    • 1042266493 scopus 로고    scopus 로고
    • High dose allergen stimulation of T cells from house dust mite-allergic subjects induces expansion of IFNgamma+ T cells, apoptosis of CD4+IL-4+ T cells and T cell anergy
    • Gardner LM, O'Hehir RE, Rolland JM. High dose allergen stimulation of T cells from house dust mite-allergic subjects induces expansion of IFNgamma+ T cells, apoptosis of CD4+IL-4+ T cells and T cell anergy. Int Arch Allergy Immunol 2004 133 : 1 13.
    • (2004) Int Arch Allergy Immunol , vol.133 , pp. 1-13
    • Gardner, L.M.1    O'Hehir, R.E.2    Rolland, J.M.3
  • 36
    • 41849113074 scopus 로고    scopus 로고
    • Two year follow-up of immunological response in mite-allergic children treated with sublingual immunotherapy. Comparison with subcutaneous administration
    • Antúnez C, Mayorga C, Corzo JL, Jurado A, Torres MJ. Two year follow-up of immunological response in mite-allergic children treated with sublingual immunotherapy. Comparison with subcutaneous administration. Pediatr Allergy Immunol 2008 19 : 210 218.
    • (2008) Pediatr Allergy Immunol , vol.19 , pp. 210-218
    • Antúnez, C.1    Mayorga, C.2    Corzo, J.L.3    Jurado, A.4    Torres, M.J.5
  • 38
    • 0034744487 scopus 로고    scopus 로고
    • TH2 lymphocytes from atopic patients treated with immunotherapy undergo rapid apoptosis after culture with specific allergens
    • Guerra F, Carracedo J, Solana-Lara R, Sanchez-Guijo P, Ramirez R. TH2 lymphocytes from atopic patients treated with immunotherapy undergo rapid apoptosis after culture with specific allergens. J Allergy Clin Immunol 2001 107 : 647 653.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 647-653
    • Guerra, F.1    Carracedo, J.2    Solana-Lara, R.3    Sanchez-Guijo, P.4    Ramirez, R.5
  • 39
    • 60849124499 scopus 로고    scopus 로고
    • Allergen-related approaches to immunotherapy
    • Rolland J, Gardner LM, O'Heir RE. Allergen-related approaches to immunotherapy. Pharmacol Ther 2009 121 : 273 284.
    • (2009) Pharmacol Ther , vol.121 , pp. 273-284
    • Rolland, J.1    Gardner, L.M.2    O'Heir, R.E.3
  • 40
    • 0028901793 scopus 로고
    • Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen stimulated T cell cultures
    • Jutel M, Pichler WJ, Skrbic D, Urwyler A, Dahinden C, Muller UR. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen stimulated T cell cultures. J Immunol 1995 154 : 4187 4194.
    • (1995) J Immunol , vol.154 , pp. 4187-4194
    • Jutel, M.1    Pichler, W.J.2    Skrbic, D.3    Urwyler, A.4    Dahinden, C.5    Muller, U.R.6
  • 41
    • 0030870124 scopus 로고    scopus 로고
    • IL-5 production by allergen stimulated T cells following grass pollen immunotherapy for seasonal allergic rhinitis
    • Till S, Walker S, Dickason R et al. IL-5 production by allergen stimulated T cells following grass pollen immunotherapy for seasonal allergic rhinitis. Clin Exp Immunol 1997 110 : 114 121.
    • (1997) Clin Exp Immunol , vol.110 , pp. 114-121
    • Till, S.1    Walker, S.2    Dickason, R.3
  • 42
    • 54549125865 scopus 로고    scopus 로고
    • Carry-over effect on IFN-gamma production induced by allergen-specific immunotherapy
    • Ciprandi G, Sormani MP, Filaci G, Fenoglio D. Carry-over effect on IFN-gamma production induced by allergen-specific immunotherapy. Int Immunopharmacol 2008 8 : 1622 1625.
    • (2008) Int Immunopharmacol , vol.8 , pp. 1622-1625
    • Ciprandi, G.1    Sormani, M.P.2    Filaci, G.3    Fenoglio, D.4
  • 43
    • 33845373253 scopus 로고    scopus 로고
    • Cry-consensus peptide, a novel peptide for immunotherapy of Japanese cedar pollinosis, induces Th1-predominant response in Cry j 1-sensitized B10.S mice
    • Kozutsumi D, Tsunematsu M, Yamaji T, Murakami R, Yokoyama M, Kino K. Cry-consensus peptide, a novel peptide for immunotherapy of Japanese cedar pollinosis, induces Th1-predominant response in Cry j 1-sensitized B10.S mice. Biol Pharm Bull 2006 29 : 2506 2509.
    • (2006) Biol Pharm Bull , vol.29 , pp. 2506-2509
    • Kozutsumi, D.1    Tsunematsu, M.2    Yamaji, T.3    Murakami, R.4    Yokoyama, M.5    Kino, K.6
  • 44
    • 34250197818 scopus 로고    scopus 로고
    • Immunomodulatory effects of viral TLR ligands on experimental asthma depend on the additive effects of IL-12 and IL-10
    • Sel S, Wegmann M, Sel S et al. Immunomodulatory effects of viral TLR ligands on experimental asthma depend on the additive effects of IL-12 and IL-10. J Immunol 2007 178 : 7805 7813.
    • (2007) J Immunol , vol.178 , pp. 7805-7813
    • Sel, S.1    Wegmann, M.2    Sel, S.3
  • 45
    • 0030003889 scopus 로고    scopus 로고
    • Grass pollen immunotherapy inhibits allergen-induced infiltration of CD41 T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon gamma
    • Durham SR, Ying S, Varney VA et al. Grass pollen immunotherapy inhibits allergen-induced infiltration of CD41 T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon gamma. J Allergy Clin Immunol 1996 97 : 1356 1365.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 1356-1365
    • Durham, S.R.1    Ying, S.2    Varney, V.A.3
  • 46
    • 0035016912 scopus 로고    scopus 로고
    • Grass pollen immunotherapy: Symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season
    • Wilson DR, Nouri-Aria KT, Walker SM et al. Grass pollen immunotherapy: Symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season. J Allergy Clin Immunol 2001 107 : 971 976.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 971-976
    • Wilson, D.R.1    Nouri-Aria, K.T.2    Walker, S.M.3
  • 47
    • 0036164580 scopus 로고    scopus 로고
    • Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1: Th2 cytokine ratios
    • Wachholz PA, Nouri-Aria KT, Wilson DR et al. Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1: Th2 cytokine ratios. Immunology 2002 105 : 56 62.
    • (2002) Immunology , vol.105 , pp. 56-62
    • Wachholz, P.A.1    Nouri-Aria, K.T.2    Wilson, D.R.3
  • 48
    • 21344441958 scopus 로고    scopus 로고
    • IL-9 and c-Kit1mast cells in allergic rhinitis during seasonal allergen exposure: Effect of immunotherapy
    • Nouri-Aria KT, Pilette C, Jacobson MR, Watanabe H, Durham SR. IL-9 and c-Kit1mast cells in allergic rhinitis during seasonal allergen exposure: effect of immunotherapy. J Allergy Clin Immunol 2005 116 : 73 9.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 73-9
    • Nouri-Aria, K.T.1    Pilette, C.2    Jacobson, M.R.3    Watanabe, H.4    Durham, S.R.5
  • 49
    • 33751226250 scopus 로고    scopus 로고
    • Basophil interleukin 4 and interleukin 13 production is suppressed during the early phase of rush immunotherapy
    • Plewako H, Wosinska K, Arvidsson M et al. Basophil interleukin 4 and interleukin 13 production is suppressed during the early phase of rush immunotherapy. Int Arch Allergy Immunol 2006 141 : 346 353.
    • (2006) Int Arch Allergy Immunol , vol.141 , pp. 346-353
    • Plewako, H.1    Wosinska, K.2    Arvidsson, M.3
  • 50
    • 0031041686 scopus 로고    scopus 로고
    • Increases in IL-12 messenger RNA1 cells accompany inhibition of allergen-induced late skin responses after successful grass pollen immunotherapy
    • Hamid QA, Schotman E, Jacobson MR, Walker SM, Durham SR. Increases in IL-12 messenger RNA1 cells accompany inhibition of allergen-induced late skin responses after successful grass pollen immunotherapy. J Allergy Clin Immunol 1997 99 : 254 260.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 254-260
    • Hamid, Q.A.1    Schotman, E.2    Jacobson, M.R.3    Walker, S.M.4    Durham, S.R.5
  • 51
    • 33750137653 scopus 로고    scopus 로고
    • Production of interleukin-12 by monocytes and interferon-gamma by natural killer cells in allergic patients during rush immunotherapy
    • Plewako H, Wosinska K, Arvidsson M, Bjorkander J, Hakansson L, Rak S. Production of interleukin-12 by monocytes and interferon-gamma by natural killer cells in allergic patients during rush immunotherapy. Ann Allergy Asthma Immunol 2006 97 : 464 468.
    • (2006) Ann Allergy Asthma Immunol , vol.97 , pp. 464-468
    • Plewako, H.1    Wosinska, K.2    Arvidsson, M.3    Bjorkander, J.4    Hakansson, L.5    Rak, S.6
  • 52
    • 24744438448 scopus 로고    scopus 로고
    • The effect of Fel d 1-derived T-cell peptides on upper and lower airway outcome measurements in cat-allergic subjects
    • Alexander C, Tarzi M, Larché M, Kay AB. The effect of Fel d 1-derived T-cell peptides on upper and lower airway outcome measurements in cat-allergic subjects. Allergy 2005 60 : 1269 1274.
    • (2005) Allergy , vol.60 , pp. 1269-1274
    • Alexander, C.1    Tarzi, M.2    Larché, M.3    Kay, A.B.4
  • 53
    • 70049094943 scopus 로고    scopus 로고
    • Regulatory T cells in asthma
    • Lloyd CM, Hawrylowicz CM. Regulatory T cells in asthma. Immunity 2009 31 : 438 449.
    • (2009) Immunity , vol.31 , pp. 438-449
    • Lloyd, C.M.1    Hawrylowicz, C.M.2
  • 54
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003 4 : 330 336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 55
    • 33750365602 scopus 로고    scopus 로고
    • Immunoregulation by targeting T cells in the treatment of allergy and asthma
    • Larchè M. Immunoregulation by targeting T cells in the treatment of allergy and asthma. Curr Opin Immunol 2006 18 : 745 750.
    • (2006) Curr Opin Immunol , vol.18 , pp. 745-750
    • Larchè, M.1
  • 56
    • 4544256262 scopus 로고    scopus 로고
    • Defective suppression of Th2 cytokines by CD4CD25 regulatory T cells in birch allergics during birch pollen season
    • Grindebacke H, Wing K, Andersson AC, Suri-Payer E, Rak S, Rudin A. Defective suppression of Th2 cytokines by CD4CD25 regulatory T cells in birch allergics during birch pollen season. Clin Exp Allergy 2004 34 : 1364 1372.
    • (2004) Clin Exp Allergy , vol.34 , pp. 1364-1372
    • Grindebacke, H.1    Wing, K.2    Andersson, A.C.3    Suri-Payer, E.4    Rak, S.5    Rudin, A.6
  • 57
    • 58149306013 scopus 로고    scopus 로고
    • In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure
    • Meiler F, Zumkehr J, Klunker S, Rückert B, Akdis CA, Akdis M. In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure. J Exp Med 2008 205 : 2887 2898.
    • (2008) J Exp Med , vol.205 , pp. 2887-2898
    • Meiler, F.1    Zumkehr, J.2    Klunker, S.3    Rückert, B.4    Akdis, C.A.5    Akdis, M.6
  • 58
    • 34548699169 scopus 로고    scopus 로고
    • Demonstration of circulating allergen-specific CD4+CD25highFoxp3+ T-regulatory cells in both nonatopic and atopic individuals
    • Maggi L, Santarlasci V, Liotta F et al. Demonstration of circulating allergen-specific CD4+CD25highFoxp3+ T-regulatory cells in both nonatopic and atopic individuals. J Allergy Clin Immunol 2007 120 : 429 436.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 429-436
    • Maggi, L.1    Santarlasci, V.2    Liotta, F.3
  • 59
    • 65349113679 scopus 로고    scopus 로고
    • T cells in health and disease
    • Akdis CA. T cells in health and disease. J Allergy Clin Immunol 2009 123 : 1022 1023.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 1022-1023
    • Akdis, C.A.1
  • 60
    • 53049102495 scopus 로고    scopus 로고
    • Cord blood allergen-specific IgE is associated with reduced IFN-γ production by cord blood cells: The Protection against Allergy - Study in Rural Environments (PASTURE) study
    • Pfefferle PI, Sel S, Ege MJ et al. PASTURE Study Group. Cord blood allergen-specific IgE is associated with reduced IFN-γ production by cord blood cells: The Protection against Allergy - Study in Rural Environments (PASTURE) study. J Allergy Clin Immunol 2008 122 : 711 716.
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 711-716
    • Pfefferle, P.I.1    Sel, S.2    Ege, M.J.3    Study, Group.4
  • 61
    • 44449145067 scopus 로고    scopus 로고
    • Assessment of Bet v 1-specific CD4-T cell responses in allergic and nonallergic individuals using MHC class II peptide tetramers
    • Van Overtvelt L, Wambre E, Maillere B et al. Assessment of Bet v 1-specific CD4-T cell responses in allergic and nonallergic individuals using MHC class II peptide tetramers. J Immunol 2008 180 : 4514 4522.
    • (2008) J Immunol , vol.180 , pp. 4514-4522
    • Van Overtvelt, L.1    Wambre, E.2    Maillere, B.3
  • 62
    • 34249799275 scopus 로고    scopus 로고
    • Coming back to a missing immune deviation as the main explanatory mechanism for the hygiene hypothesis
    • Romagnani S. Coming back to a missing immune deviation as the main explanatory mechanism for the hygiene hypothesis. J Allergy Clin Immunol 2007 119 : 1511 1513.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 1511-1513
    • Romagnani, S.1
  • 63
    • 0037504093 scopus 로고    scopus 로고
    • Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy
    • Francis JN, Till SJ, Durham SR. Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy. J Allergy Clin Immunol 2003 111 : 1255 1261.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 1255-1261
    • Francis, J.N.1    Till, S.J.2    Durham, S.R.3
  • 64
    • 0027204621 scopus 로고
    • Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production
    • Del Prete G, De Carli M, Almerigogna F, Giudizi MG, Biagiotti R, Romagnani S. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol 1993 150 : 353 360.
    • (1993) J Immunol , vol.150 , pp. 353-360
    • Del Prete, G.1    De Carli, M.2    Almerigogna, F.3    Giudizi, M.G.4    Biagiotti, R.5    Romagnani, S.6
  • 65
    • 67649226607 scopus 로고    scopus 로고
    • IL-10 deficiency unleashes an influenza-specific Th17 response and enhances survival against high-dose challenge
    • McKinstry KK, Strutt TM, Buck A et al. IL-10 deficiency unleashes an influenza-specific Th17 response and enhances survival against high-dose challenge. J Immunol 2009 182 : 7353 7363.
    • (2009) J Immunol , vol.182 , pp. 7353-7363
    • McKinstry, K.K.1    Strutt, T.M.2    Buck, A.3
  • 66
    • 0035666653 scopus 로고    scopus 로고
    • Interleukin-10 levels increase in cutaneous biopsies of patients undergoing wasp venom immunotherapy
    • Nasser SM, Ying S, Meng Q, Kay AB, Ewan PW. Interleukin-10 levels increase in cutaneous biopsies of patients undergoing wasp venom immunotherapy. Eur J Immunol 2001 31 : 3704 3713.
    • (2001) Eur J Immunol , vol.31 , pp. 3704-3713
    • Nasser, S.M.1    Ying, S.2    Meng, Q.3    Kay, A.B.4    Ewan, P.W.5
  • 67
    • 44949122465 scopus 로고    scopus 로고
    • Grass pollen immunotherapy induces Foxp3-expressing CD4+CD25+ cells in the nasal mucosa
    • Radulovic S, Jacobson MR, Durham SR, Nouri-Aria KT. Grass pollen immunotherapy induces Foxp3-expressing CD4+CD25+ cells in the nasal mucosa. J Allergy Clin Immunol 2009 121 : 1467 1472.
    • (2009) J Allergy Clin Immunol , vol.121 , pp. 1467-1472
    • Radulovic, S.1    Jacobson, M.R.2    Durham, S.R.3    Nouri-Aria, K.T.4
  • 68
    • 0034744489 scopus 로고    scopus 로고
    • Local expression of epsilon germline gene transcripts and RNA for the epsilon heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma
    • Ying S, Humbert M, Meng Q et al. Local expression of epsilon germline gene transcripts and RNA for the epsilon heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma. J Allergy Clin Immunol 2001 107 : 686 692.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 686-692
    • Ying, S.1    Humbert, M.2    Meng, Q.3
  • 69
    • 54449098165 scopus 로고    scopus 로고
    • Update on mechanisms of allergen injection immunotherapy
    • James LK, Durham SR. Update on mechanisms of allergen injection immunotherapy. Clin Exp Allergy 2008 1074 1088.
    • (2008) Clin Exp Allergy , pp. 1074-1088
    • James, L.K.1    Durham, S.R.2
  • 71
    • 42549119146 scopus 로고    scopus 로고
    • Distribution of Langerhans cells and mast cells within the human oral mucosa: New application sites of allergens in sublingual immunotherapy?
    • Allam JP, Stojanovski G, Friedrichs N et al. Distribution of Langerhans cells and mast cells within the human oral mucosa: new application sites of allergens in sublingual immunotherapy? Allergy 2008 63 : 720 727.
    • (2008) Allergy , vol.63 , pp. 720-727
    • Allam, J.P.1    Stojanovski, G.2    Friedrichs, N.3
  • 72
    • 33645033082 scopus 로고    scopus 로고
    • Absence of systemic immunologic changes during dose build-up phase and early maintenance period in effective specific sublingual immunotherapy in children
    • Dehlink E, Eiwegger T, Gerstmayr M et al. Absence of systemic immunologic changes during dose build-up phase and early maintenance period in effective specific sublingual immunotherapy in children. Clin Exp Allergy 2006 36 : 32 9.
    • (2006) Clin Exp Allergy , vol.36 , pp. 32-9
    • Dehlink, E.1    Eiwegger, T.2    Gerstmayr, M.3
  • 73
    • 33748294181 scopus 로고    scopus 로고
    • Sublingual immunotherapy in children modulates allergen-induced in vitro expression of cytokine mRNA in PBMC
    • Savolainen J, Jacobsen L, Valovirta E. Sublingual immunotherapy in children modulates allergen-induced in vitro expression of cytokine mRNA in PBMC. Allergy 2006 61 : 1184 1190.
    • (2006) Allergy , vol.61 , pp. 1184-1190
    • Savolainen, J.1    Jacobsen, L.2    Valovirta, E.3
  • 74
    • 34548237449 scopus 로고    scopus 로고
    • Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation
    • Bohle B, Kinaciyan T, Gerstmayr M, Radakovics A, Jahn-Schmid B, Ebner C. Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation. J Allergy Clin Immunol 2007 120 : 707 713.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 707-713
    • Bohle, B.1    Kinaciyan, T.2    Gerstmayr, M.3    Radakovics, A.4    Jahn-Schmid, B.5    Ebner, C.6
  • 75
    • 72849130777 scopus 로고    scopus 로고
    • House dust mite sublingual immunotherapy: The role for transforming growth factor-beta and functional regulatory T cells
    • O'Hehir RE, Gardner LM, de Leon MP et al. House dust mite sublingual immunotherapy: The role for transforming growth factor-beta and functional regulatory T cells. Am J Respir Crit Care Med 2009 180 : 936 947.
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 936-947
    • O'Hehir, R.E.1    Gardner, L.M.2    De Leon, M.P.3
  • 76
    • 84855485850 scopus 로고    scopus 로고
    • Clinical outcome and IL-17, IL-23, IL-27 and FOXP3 expression in peripheral blood mononuclear cells of pollen-allergic children during sublingual immunotherapy
    • Nieminen K, Valovirta E, Savolainen J. Clinical outcome and IL-17, IL-23, IL-27 and FOXP3 expression in peripheral blood mononuclear cells of pollen-allergic children during sublingual immunotherapy. Pediatr Allergy Immunol 2010 21 : 174 184.
    • (2010) Pediatr Allergy Immunol , vol.21 , pp. 174-184
    • Nieminen, K.1    Valovirta, E.2    Savolainen, J.3
  • 78
    • 8644220382 scopus 로고    scopus 로고
    • Increased allergen concentration enhances IFN-gamma production by allergic donor T cells expressing a peripheral tissue trafficking phenotype
    • Gardner LM, Spyroglou L, O'Hehir RE, Rolland JM. Increased allergen concentration enhances IFN-gamma production by allergic donor T cells expressing a peripheral tissue trafficking phenotype. Allergy 2004 59 : 1308 1317.
    • (2004) Allergy , vol.59 , pp. 1308-1317
    • Gardner, L.M.1    Spyroglou, L.2    O'Hehir, R.E.3    Rolland, J.M.4
  • 79
    • 0037086525 scopus 로고    scopus 로고
    • CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons
    • MacDonald AJ, Duffy M, Brady MT et al. CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons. J Infect Dis 2002 185 : 720 727.
    • (2002) J Infect Dis , vol.185 , pp. 720-727
    • MacDonald, A.J.1    Duffy, M.2    Brady, M.T.3
  • 80
    • 1342282321 scopus 로고    scopus 로고
    • A role for IL-10-mediated HLA-DR7-restricted T cell-dependent events in development of the modified Th2 response to cat allergen
    • Reefer AJ, Carneiro RM, Custis NJ et al. A role for IL-10-mediated HLA-DR7-restricted T cell-dependent events in development of the modified Th2 response to cat allergen. J Immunol 2004 172 : 2763 2772.
    • (2004) J Immunol , vol.172 , pp. 2763-2772
    • Reefer, A.J.1    Carneiro, R.M.2    Custis, N.J.3
  • 81
    • 0031984482 scopus 로고    scopus 로고
    • Influence of both TCR repertoire and severity of the atopic status on the cytokine secretion profile of Parietaria officinalis-specific T cells
    • Parronchi P, Sampognaro S, Annunziato F et al. Influence of both TCR repertoire and severity of the atopic status on the cytokine secretion profile of Parietaria officinalis-specific T cells. Eur J Immunol 1998 28 : 37 46.
    • (1998) Eur J Immunol , vol.28 , pp. 37-46
    • Parronchi, P.1    Sampognaro, S.2    Annunziato, F.3
  • 82
    • 34147136217 scopus 로고    scopus 로고
    • TLR agonists induce regulatory dendritic cells to recruit Th1 cells via preferential IP-10 secretion and inhibit Th1 proliferation
    • Qian C, An H, Yu Y, Liu S, Cao X. TLR agonists induce regulatory dendritic cells to recruit Th1 cells via preferential IP-10 secretion and inhibit Th1 proliferation. Blood 2007 109 : 3308 3315.
    • (2007) Blood , vol.109 , pp. 3308-3315
    • Qian, C.1    An, H.2    Yu, Y.3    Liu, S.4    Cao, X.5
  • 83
    • 44849100683 scopus 로고    scopus 로고
    • Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection
    • Bozza S, Zelante T, Moretti S et al. Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection. J Immunol 2008 180 : 4022 4031.
    • (2008) J Immunol , vol.180 , pp. 4022-4031
    • Bozza, S.1    Zelante, T.2    Moretti, S.3
  • 84
    • 33745666983 scopus 로고    scopus 로고
    • Ultra-rush venom immunotherapy induces differential T cell activation and regulatory patterns according to the severity of allergy
    • Mamessier E, Birnbaum J, Dupuy P et al. Ultra-rush venom immunotherapy induces differential T cell activation and regulatory patterns according to the severity of allergy. Clin Exp Allergy 2006 36 : 704 713.
    • (2006) Clin Exp Allergy , vol.36 , pp. 704-713
    • Mamessier, E.1    Birnbaum, J.2    Dupuy, P.3
  • 85
    • 67651215706 scopus 로고    scopus 로고
    • Clinical efficacy and immune regulation with peanut oral immunotherapy
    • Jones SM, Pons L, Roberts JL et al. Clinical efficacy and immune regulation with peanut oral immunotherapy. J Allergy Clin Immunol 2009 124 : 292 300.
    • (2009) J Allergy Clin Immunol , vol.124 , pp. 292-300
    • Jones, S.M.1    Pons, L.2    Roberts, J.L.3
  • 86
    • 33644746130 scopus 로고    scopus 로고
    • Sublingual immunotherapy with Dermatophagoides monomeric allergoid down-regulates allergen-specific immunoglobulin e and increases both interferon-gamma- and interleukin 10-production
    • Cosmi L, Santarlasci V, Angeli R et al. Sublingual immunotherapy with Dermatophagoides monomeric allergoid down-regulates allergen-specific immunoglobulin E and increases both interferon-gamma- and interleukin 10-production. Clin Exp Allergy 2006 36 : 261 272.
    • (2006) Clin Exp Allergy , vol.36 , pp. 261-272
    • Cosmi, L.1    Santarlasci, V.2    Angeli, R.3
  • 87
    • 9244223651 scopus 로고    scopus 로고
    • Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity
    • Stock P, Akbari O, Berry G, Freeman GJ, Dekruyff RH, Umetsu DT. Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nat Immunol 2004 5 : 1149 1156.
    • (2004) Nat Immunol , vol.5 , pp. 1149-1156
    • Stock, P.1    Akbari, O.2    Berry, G.3    Freeman, G.J.4    Dekruyff, R.H.5    Umetsu, D.T.6
  • 88
    • 0035914926 scopus 로고    scopus 로고
    • Regulatory role of T cells producing both interferon gamma and interleukin 10 in persistent infection
    • Trinchieri G. Regulatory role of T cells producing both interferon gamma and interleukin 10 in persistent infection. J Exp Med 2001 194 : F53 7.
    • (2001) J Exp Med , vol.194 , pp. 53-7
    • Trinchieri, G.1
  • 89
    • 18244391173 scopus 로고    scopus 로고
    • T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity
    • Verhoef A, Alexander C, Kay AB, Larchè M. T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity. PLoS Med 2005 2 : 253 261.
    • (2005) PLoS Med , vol.2 , pp. 253-261
    • Verhoef, A.1    Alexander, C.2    Kay, A.B.3    Larchè, M.4
  • 90
    • 33847144180 scopus 로고    scopus 로고
    • Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
    • Jankovic D, Kullberg MC, Feng CG et al. Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J Exp Med 2007 204 : 273 283.
    • (2007) J Exp Med , vol.204 , pp. 273-283
    • Jankovic, D.1    Kullberg, M.C.2    Feng, C.G.3
  • 91
    • 33847163271 scopus 로고    scopus 로고
    • CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis
    • Anderson CF, Oukka M, Kuchroo VJ, Sacks D. CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J Exp Med 2007 204 : 285 297.
    • (2007) J Exp Med , vol.204 , pp. 285-297
    • Anderson, C.F.1    Oukka, M.2    Kuchroo, V.J.3    Sacks, D.4
  • 92
    • 33847165817 scopus 로고    scopus 로고
    • Interleukin-10 production by effector T cells: Th1 cells show self control
    • Trinchieri G. Interleukin-10 production by effector T cells: Th1 cells show self control. J Exp Med 2007 204 : 239 243.
    • (2007) J Exp Med , vol.204 , pp. 239-243
    • Trinchieri, G.1
  • 93
    • 66049149509 scopus 로고    scopus 로고
    • Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood
    • Häringer B, Lozza L, Steckel B, Geginat J. Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood. J Exp Med 2009 206 : 1009 1017.
    • (2009) J Exp Med , vol.206 , pp. 1009-1017
    • Häringer, B.1    Lozza, L.2    Steckel, B.3    Geginat, J.4
  • 94
    • 68149100383 scopus 로고    scopus 로고
    • Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells
    • Gabrysová L, Nicolson KS, Streeter HB et al. Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells. J Exp Med 2009 206 : 1755 1767.
    • (2009) J Exp Med , vol.206 , pp. 1755-1767
    • Gabrysová, L.1    Nicolson, K.S.2    Streeter, H.B.3
  • 96
    • 36248951161 scopus 로고    scopus 로고
    • Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
    • Stumhofer JS, Silver JS, Laurence A et al. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol 2007 8 : 1363 1371.
    • (2007) Nat Immunol , vol.8 , pp. 1363-1371
    • Stumhofer, J.S.1    Silver, J.S.2    Laurence, A.3
  • 97
    • 60549100776 scopus 로고    scopus 로고
    • Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7
    • Vultaggio A, Nencini F, Fitch PM et al. Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7. J Immunol 2009 182 : 880 899.
    • (2009) J Immunol , vol.182 , pp. 880-899
    • Vultaggio, A.1    Nencini, F.2    Fitch, P.M.3
  • 98
    • 50649120499 scopus 로고    scopus 로고
    • Toll-like receptor 2 agonist Pam3CSK4 enhances the induction of antigen-specific tolerance via the sublingual route
    • Lombardi V, Van Overtvelt L, Horiot S et al. Toll-like receptor 2 agonist Pam3CSK4 enhances the induction of antigen-specific tolerance via the sublingual route. Clin Exp Allergy 2008 38 : 1819 1829.
    • (2008) Clin Exp Allergy , vol.38 , pp. 1819-1829
    • Lombardi, V.1    Van Overtvelt, L.2    Horiot, S.3
  • 99
    • 33749436870 scopus 로고    scopus 로고
    • Immunotherapy with a ragweed-Toll like receptor 9 agonist vaccine for allergic rhinitis
    • Creticos PS, Schroeder JT, Hamilton RG et al. Immunotherapy with a ragweed-Toll like receptor 9 agonist vaccine for allergic rhinitis. N Engl J Med 2006 355 : 1445 1455.
    • (2006) N Engl J Med , vol.355 , pp. 1445-1455
    • Creticos, P.S.1    Schroeder, J.T.2    Hamilton, R.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.