Carry-over effect on IFN-gamma production induced by allergen-specific immunotherapy

International Immunopharmacology

Volumn 8, Issue 12, 2008, Pages 1622-1625

  Ciprandi, Giorgio ^a   Sormani, Maria Pia ^b   Filaci, Gilberto ^a   Fenoglio, Daniela ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Allergic rhinitis; ELISPOT; IFN production; Mites; Pollens; Th1 cells

Indexed keywords

GAMMA INTERFERON; HOUSE DUST ALLERGEN; PLACEBO; POLLEN ANTIGEN;

ADOLESCENT; ADULT; AGED; ALLERGIC RHINITIS; ARTICLE; BIRCH; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATOPHAGOIDES FARINAE; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; HUMAN; IMMUNOSTIMULATION; IMMUNOTHERAPY; MALE; OPEN STUDY; PARIETARIA; POACEAE; POLLEN ALLERGY; PRIORITY JOURNAL; SUBLINGUAL IMMUNOTHERAPY; TH1 CELL; TH2 CELL;

ADOLESCENT; ADULT; AGED; ANTIGENS, DERMATOPHAGOIDES; DESENSITIZATION, IMMUNOLOGIC; FEMALE; HUMANS; INTERFERON-GAMMA; MALE; MIDDLE AGED; RHINITIS, ALLERGIC, SEASONAL;

EID: 54549125865     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2008.07.007     Document Type: Article

References (15)

1. Durham S., Ying S., Varney V.A., Jacobson M.R., Sudderick R.M., Mackay I.S., et al. Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia. J Immunol 148 (1992) 2390-2394
2. Imada M., Simons E.F., Jay F.T., and Hayglass K.T. Allergen-stimulated interleukin-4 and interferon-gamma production in primary culture: responses of subjects with allergic rhinitis and normal controls. Immunol 85 (1995) 373-380
3. Bousquet J., Lockey R.F., and Malling H.J. WHO position paper. Allergen immunotherapy: therapeutic vaccines for allergic disease. Allergy 53 S44 (1998) 1-42
4. Jutel M., Pichler W.J., Skrbic D., Urwyler A., Dahinden C., and Muller U.R. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-γ secretion in specific allergen-stimulated T cell cultures. J Immunol 154 (1995) 4187-4194
5. Wilson D.R., Nouri-Aria K.T., Walker S.M., Pajno G.B., O'Brien F., Jacobson M.R., et al. Grass pollen immunotherapy: symptomatic improvement correlates with reduction in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season. J Allergy Clin Immunol 107 (2001) 971-976
6. Arikan C., Bahceciler N.N., Deniz G., Akdis M., Akkoc T., Akdis C.A., et al. Bacillus Calmette-guerin-induced interleukin-12 did not additionally improve clinical and immunologic parameters in asthmatic children treated with sublingual immunotherapy. Clin Exp Allergy 34 (2004) 398-405
7. Cosmi L., Santarlasci V., Angeli R., Liotta F., Maggi L., Frosali F., et al. Sublingual immunotherapy with Dermatophagoides monomeric allergoid down-regulates allergen-specific immunoglobulin E and increases both interferon-γ- and interleukin-10-production. Clin Exp Allergy 36 (2006) 261-272
8. Passalacqua G., and Durham S.R. Allergic rhinitis and its impact on asthma update: allergen immunotherapy. J Allergy Clin Immunol 119 (2007) 881-891
9. Bousquet P.J., Combescure C., Neukirch F., Klossek J.M., Mechin H., Daures J.P., and Bousquet J. Visual analog scales can assess the severity of rhinitis graded according to ARIA guidelines. Allergy 62 (2007) 367-372
10. Ciprandi G, De Amici M, Murdaca G, Colombo BM, Quaglini S, Marseglia GL, et al. Serum IL-4 as a Marker of Immunological Response to Sublingual Immunotherapy. J Biol Reg Hom Ag (in press).
11. Asemissen A.M., Nagorsen D., Keilholz U., Letsch A., Schmittel A., Thiel E., et al. Flow cytometric determination of intracellular or secreted IFNgamma for the quantification of antigen reactive T cells. J Immunol Methods. 251 (2001) 101-108
12. Schmittel A., Keilholz U., and Scheibenbogen C. Evaluation of the interferon-gamma ELISPOT-assay for quantification of peptide specific T lymphocytes from peripheral blood. J Immunol Methods. 210 (1997) 167-174
13. Bernasconi N.L., Traggiai E., and Lanzavecchia A. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 298 (2002) 2199-2202
14. McHeyzer-Williams L.J., Malherbe L.P., and McHeyzer-Williams M.G. Checkpoints in memory B-cell evolution. Immunological Reviews 211 (2006) 255-268
15. Lanzavecchia A., Bernasconi N., Traggiai E., Ruprecht C.L., Corti D., and Sallusto F. Understanding and making use of human memory B cells. Immunological Reviews 211 (2006) 303-309