Effects of sublingual immunotherapy on allergic inflammation

Inflammation and Allergy - Drug Targets

Volumn 7, Issue 3, 2008, Pages 167-172

  Incorvaia, Cristoforo ^a   Frati, Franco ^b,c   Puccinelli, Paola ^b   Marcucci, Francesco ^c   Di Cara, Giuseppe ^c   Sensi, Laura ^c   Scurati, Silvia ^b   Yacoub, Mona Rita ^d   Moingeon, Philippe ^e  

^a ICP Hospital   (Italy)

^b Medical and Scientific Department   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

^d SAN RAFFAELE HOSPITAL   (Italy)

^e Stallergenes SA   (France)

Author keywords

Allergic inflammation; Cytokines; Dendritic cells; Oral biopsies; Sublingual immunotherapy; T cells

Indexed keywords

ALLERGEN; CHEMOKINE; CYTOKINE; POLLEN EXTRACT;

ALLERGIC INFLAMMATION; ANTIBODY PRODUCTION; ANTIGEN PRESENTING CELL; ANTIINFLAMMATORY ACTIVITY; ASTHMA; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG MEGADOSE; EFFECTOR CELL; EOSINOPHIL; HUMAN; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOTHERAPY; INFLAMMATION; MAST CELL; REGULATORY T LYMPHOCYTE; REVIEW; RISK FACTOR; T LYMPHOCYTE; DESENSITIZATION; HYPERSENSITIVITY; IMMUNOLOGY; METABOLISM; SUBLINGUAL DRUG ADMINISTRATION; TH1 CELL; TH2 CELL;

ADMINISTRATION, SUBLINGUAL; ALLERGENS; CYTOKINES; DENDRITIC CELLS; DESENSITIZATION, IMMUNOLOGIC; EOSINOPHILS; HUMANS; HYPERSENSITIVITY; INFLAMMATION; MAST CELLS; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH2 CELLS;

EID: 55249102197     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152808785748191     Document Type: Review

References (102)

1. Adkinson, N.F.; Yunginger, J.W.; Busse, W.W.; Bochner, B.; Simons F.E.; Holgate S.T. Middleton's Allergy. Principles and Practice, Mosby: St. Louis, 2008.
2. Bharadway, A.S.; Bewtra, A.K.; Agrawal, D.K. Can. J. Physiol. Pharmacol., 2007, 85, 686-699.
3. Langlois, R.A.; Legge, K.L. Immunol. Res., 2007, 39, 128-145.
4. Van Loon, L.A.; Krieg, S.R.; Davidson, C.L.; Bos, J.D. J. Oral Pathol. Med., 1989, 18, 197-201.
5. Allam, J.P.; Novak, N.; Fuchs, C.; Asen, S.; Bergé, S.; Appel, T.; Geiger, E.; Kochen, J.P.; Bieber, T. J. Allergy Clin. Immunol., 2003, 112, 141-148.
6. Von Bubnoff, D.; Fimmers, R.; Bogdanov, M.; Matz, H.; Koch S.; Bieber, T. Clin. Exp. Allergy, 2004, 34, 1056-1063.
7. Novak, N.; Bieber, T.; Leung, D.Y.M. J. Allergy Clin. Immunol., 2003, 112, S128-S139.
8. Romagnani, S. J. Allergy Clin. Immunol., 2000, 105, 399-408.
9. Holt, P.G.; Stumbles, P.A. J. Allergy Clin. Immunol., 2000, 105, 421-429
10. Larchè, M.; Robinson, D.S.; Kay, A.B. J. Allergy Clin. Immunol., 2003, 111, 450-463.
11. Roncarolo, M.G.; Levings, M.K. Curr. Opin. Immunol., 2000, 12, 676-683.
12. McHugh, R.S.; Shevah, E.M. J. Allergy Clin. Immunol., 2002, 111, 693-702.
13. Umetsu, D.T; Akbari, O., DeKruyff, R.H. J. Allergy Clin. Immunol., 2003, 112, 480-487.
14. Nielsen, J.; Holm, T.L.; Claesson, M.H. APMIS, 2004, 112, 642-650.
15. O'Garra, A.; Vieira, P. Nat. Med., 2004, 10, 81-805.
16. Taylor, A.; Verhagen, J.; Blaser, K.; Akdis, M.; Akdis, C.A. Immunology, 2006, 117, 433-442.
17. Bellinghausen, I.; Knop, J.; Saloga, J. Int. Arch. Allergy Immunol., 2001, 126, 97-101.
18. Schramm, C.; Herz, U.; Podlech, J. J. Immunol., 2003, 170, 1313-1319.
19. Akdis, M.; Blaser, K.; Akdis, C.A. J. Allergy Clin. Immunol., 2005, 116, 961-968.
20. Meyer, E.H.; Dekruyff, R.H.; Umetsu, D.T. Annu. Rev. Med., 2008, 58, 1813-1818.
21. Prussin, C.; Metcalfe, D.D. J. Allergy Clin. Immunol., 2006, 117, S450-456.
22. Schwartz, L.B. Clin. Allergy Immunol., 2002, 16, 3-42.
23. Marone, G.; Triggiani, M.; de Paulis, A. Trends Immunol., 2005, 26, 25-31.
24. Schroeder, J.T.; MacGlashan, D.W.; Lichtenstein, L.M. Adv. Immunol., 2001, 77, 93-122.
25. Nakamura, H.; Higashigawa, F.; Nobukumi, J. Int. Arch. Allergy Immunol., 2007, 142, 329-334.
26. Kay, A.B.; Klion, A.D. Immunol. Allergy Clin. North Am., 2004, 24, 645-666.
27. Bochner, B.S. J. Allergy Clin. Immunol., 2000, 106, S292-302.
28. Steinke, J.W.; Borish, L. J. Allergy Clin. Immunol., 2006, 117, S441-445.
29. Schmidt-Weber, C.B.; Akdis, M.; Akdis, C.A. J. Allergy Clin. Immunol., 2007, 120, 247-54.
30. Yoshimoto, T.; Tsutsui, H.; Tominaga, K.; Hoshino, K.; Okamura, H.; Akira, S.; Paul, W.E.; Nakanishi, K. Proc. Natl. Acad. Sci. USA, 1999, 96, 13962-13966.
31. Liao, S.C.; Cheng, Y.C.; Wang, Y.C. J. Immunol., 2004, 173, 6712-6718.
32. Dillon, S.R.; Sprecher, C.; Hammond, A.; Bilsborough, J.; Rosenfeld-Franklin, M.; Presnell, S.R.; Haugen, H.S.; Maurer, M.; Harder, B.; Johnston, J.; Bort, S.; Mudri, S.; Kuijper, J.L.; Bukowski, T.; Shea, P.; Dong, D.L.; Dasovich, M.; Grant, F.J.; Lockwood, L.; Levin, S.D.; Le Ciel, C.; Waggie, K.; Day, H.; Topouzis, S.; Kramer, J.; Kuestner, R.; Chen, Z.; Foster, D, Parrish-Novak, J, Gross, J.A. Nat. Immunol., 2004, 7, 752-760.
33. Kim, S.H.; Ham, S.H.; Azam, T.; Yoon, D.Y.; Dinarello, C.A. Immunity, 2005, 22, 131-142.
34. Bousquet, J.; Lockey, R.; Malling, H.J. Allergy, 1998, 53 (suppl. 54).
35. Li, J.; Lockey, R.F.; Bernstein, I.L.; Portnoy, J.M.; Nicklas, R.A. Ann. Allergy Asthma Immunol., 2003, 90 (suppl 1), 1-40.
36. Garcia-Marcos, L; Lucas Moreno, J.M.; Garde, J.G. Inflamm. Allergy Drug Targets, 2007, 6, 117-126.
37. Passalacqua, G.; Valovirta, E.; van Weissenbruch, R.; Frati, F.; Incorvaia, C.; Puccinelli, P. Sublingual specific immunotherapy. From scientific background to clinical practice. Sinergie: Milan, 2007.
38. Schmidt-Weber, C.B.; Blaser, K. Inflamm. Allergy Drug Targets, 2006, 5, 15-21.
39. Akdis, M., Akdis, C.A. J. Allergy Clin. Immunol., 2007, 119, 780-789.
40. Moingeon, P.; Batard, T.; Fadel, R.; Frati, F.; Sieber, J.; Overtvelt, L. Allergy, 2006, 61, 151-65.
41. Frati, F.; Moingeon, F.; Marcucci, F.; Puccinelli, P.; Sensi, L.; Di Cara, G.; Incorvaia, C. Allergy Asthma Proc., 2007, 28, 35-39.
42. Incorvaia, C.; Frati, F.; Sensi, L.; Riario-Sforza, G.G.; Marcucci, F. Rec. Pat. Inflammation Allergy Drug Discov., 2007, 1, 35-38.
43. Faria, A.M., Weimer, H.L. Adv. Immunol., 1999, 73, 153-264.
44. van Wilsem, E.J.; Breve, J.; Savelkoul, H.; Claessen, A.; Scheper, R.J.; Kraal, G. Immunobiology, 1995, 194, 403-414.
45. Noirey, N.; Rougier, N.; André, C.; Schmitt, D.; Vincent, C. J. Allergy Clin. Immunol., 2000, 105, 1194-1201.
46. Aoyama-Kondo, T.; Yoshida, T.; Tsobe, K.; Nakayama, A.; Asai, J.; Oka, T.; Nakashima, I. Immunobiology, 1992, 184, 372-383.
47. Van Helvoort, J.M.; Samson, J.; Chantry, D.; Jansen, W.; Schadee-Eestermans, I.; Thepen, T.; Mebius, R.; Kraal, G. Allergy, 2004, 59, 1211-1218.
48. Martin-Fotecha, A.; Sebastiani, S.; Höpken, U.; Uguccioni, M.; Lipp, M.; Lanzavecchia, A.; Sallusto, F. J. Exp. Med., 2003, 198, 615-621.
49. Allam, J.P.; Peng, W.M.; Appel, T.; Wenghofer, M.; Niederhagen, B.; Bieber, T.; Bergè, S, Novak, N. J. Allergy Clin. Immunol., 2008, 121, 368-374.
50. Romagnani, S. Allergy, 2006, 61, 3-14.
51. Durham, S.R.; Till, S.J. J. Allergy Clin. Immunol., 1998, 102, 157-164.
52. Jutel, M.; Akdis, M.; Blaser, K.; Akdis, C.A. Allergy, 2006, 61, 796-807.
53. Akdis, C.A.; Blaser, K. FASEB J., 1999, 13, 603-609.
54. Blaser, K.; Akdis C.A. Clin. Exp. Allergy, 2004, 34, 328-331.
55. Ling, E.M.; Smith, T.; Nguyen, X.D.; Pridgeon, C.; Dallman, M.; Arbery, J.; Carr, V.A.; Robinson, D.S. Lancet, 2004, 363, 608-615.
56. Akdis, M.; Verhagen, J.; Taylor, A.; Karamloo, F.; Karagiannidis, C.; Crameri, R.; Thunberg, S.; Deniz, G.; Valenta, R.; Fiebig, H.; Kagel, C.; Disch, R.; Schmidt-Weber, C.B.; Blaser, K.; Akdis, C.A. J. Exp. Med., 2004, 199, 1567-1575.
57. McHugh, R.S.; Shevach, E.M. J. Allergy Clin. Immunol., 2002, 111, 693-702.
58. Bellinghausen, I.; Knop, J.; Saloga, J. Int. Arch. Allergy Immunol., 2001, 126, 97-101.
59. Jutel, M.; Akdis, M.; Budak, F.; Aebischer-Casaulta, C.; Wrzyszcz, M.; Blaser, K.; Akdis, C.A. Eur. J. Immunol., 2003, 33, 1205-1214.
60. Savolainen, J.; Laaksonen, K.; Rantio-Lehtimski, G.; Terho, E.O. Clin. Exp. Allergy, 2004, 34, 413-419.
61. Koulis, A.; Robinson D.G. Clin. Exp. Allergy, 2000, 30, 747-750.
62. Homer, A.A.; Van Uden, J.H.; Zubeldia, J.M.; Broide, D.; Raz, E. Immunol. Rev., 2001, 179, 102-118.
63. Ciprandi, G.; Fenoglio, D.; Cirillo, I.; Vizzaccaro, A.; Ferrera, A.; Tosca, M.A.; Puppo, F. Ann. Allergy Asthma Immunol., 2005, 95, 38-44.
64. Bohle, B.; Kinaciyan, T.; Gerstmayr, M.; Radakovics, A.; Jahn-Schmid, B.; Ebner, C. J. Allergy Clin. Immunol., 2007, 120, 707-713.
65. Ippoliti, F.; De Santis, W.; Volterrani, A.; Lenti, L.; Canitano, N.; Lucarelli, S.; Frediani, T. Ped. Allergy Immunol., 2003, 14, 216-221.
66. Schramm, C.; Herz, U.; Podlech, J.; Protschka, M,; Finotto, S.; Reddehase, M.J.; Kohler, H.; Galle, P.R.; Lohse, A.W.; Blessing, M. J. Immunol., 2003, 170, 1313-1319.
67. Schmidt-Weber, C.B.; Blaser, K. Curr. Opin. Immunol., 2004, 16, 709-716.
68. Okamura, H.; Tsutsi, H.; Komatsu, T.; Yutsudo, M.; Hakura, A.; Tanimoto, T.; Tongoe, K.; Okura, T.; Nukata, Y.; Hattori, K. Nature, 1995, 6552, 88-91.
69. Savolainen, J.; Nieminen, K.; Laaksonen, K.; Laiho, T, Jacobsen, L.; Lahesmaa, R.; Terho, E.O.; Valovirta, P. Allergy, 2007, 62, 949-53.
70. Lichtenstein, L.M.; Holtzman, N.A.; Burnett, L.S. J. Immunol., 1968, 101, 312-318.
71. Busse, W.W.; Rosenwasser, L.J. J. Allergy Clin. Immunol., 2003, 111, S799-804.
72. Nouri-Aria, K.T.; Wachholz, P.A.; Francis, J.N.; Jacobson, M.R.; Walker, S.M.; Wilcock, L.K.; Staple, S.Q.; Aalberse, R.C.; Till, S.J.; Durham, S.R. J. Immunol., 2004, 172, 3252-3259.
73. Bousquet, J.; van Cauwenberge, P. (eds). J. Allergy Clin. Immunol. 2001, 108(suppl 5), 147-334.
74. Bousquet, J.; Scheinmann, P.; Guinnepain, M.T.; Perrin-Fayolle, M.; Sauvaget, J.; Tonnel, A.B.; Pauli, G.; Caillaud, D.; Dubost, R.; Leynadier, F.; Vervloet, D.; Herman, D.; Galvain, S.; André, C. Allergy, 1999, 54, 249-260.
75. La Rosa, M.; Ranno, C.; André, C.; Carat, F.; Tosca, M.A.; Canonica, G.W. J. Allergy Clin. Immunol., 1999, 104, 425-432.
76. Clavel, R.; Bousquet, J.; André, C. Allergy, 1998, 53, 493-498.
77. Wilson, D.R.; Torres Lima, M.; Durham, S.R. Allergy, 2005, 60, 4-12.
78. Didier, A.; Malling, H.J.; Worm, M.; Horak, F.; Jager, S.; Montagut, A.; Andrè, C.; de Beaumont, O.; Melac, M. J. Allergy Clin. Immunol., 2007, 120, 1338-1245.
79. Troise, C.; Voltolini, S.; Canessa, A.; Pecora, S.; Negrini, A.C. J. Invest. Allergol. Clin. Immunol., 1995, 5, 25-30.
80. Torres Lima, M.; Wilson, D.; Pitkin, L.; Roberts, A.; Nouri-Aria, K.; Jacobson, M.; Walker, S.; Durham, S.R. Clin. Exp. Allergy, 2002, 32, 507-514.
81. Malling, H.J.; Lund, L.; Ipsen, H.; Poulsen, L. J. Invest. Allergol. Clin. Immunol., 2006, 16, 162-168.
82. Bahceciler, N.; Arikan, C.; Taylor, A.; Akdis, M.; Blaser, K.; Barlan, I.; Akdis C. Int. Arch. Allergy Immunol., 2005, 136, 287-294.
83. Flicker, S.; Valenta, R. Int. Arch. Allergy Immunol., 2003, 132, 13-24.
84. van Neerven, R.J.; Wikborg, T.; Lund, G.; Jacobsen, B.; Brinch-Nielsen, A.; Arnved, J.; Ipsen, H. J. Immunol., 1999, 163, 2944-2952.
85. van Neerven R.J.; Arvidsson, M.; Ipsen, H.; Sparholt, S.H.; Rak, S.; Würtzen, P.A. Clin. Exp. Allergy, 2004, 34, 420-428.
86. Naclerio, R.M.; Meier, H.L.; Kagey-Sobotka, A.; Adkinson, N.F.; Meyers, D.A.; Norman, P.S., Lichtenstein, L.M. Am. Rev. Respir. Dis., 1983, 128, 597-602.
87. Creticos, P.S.; Marsh, D.G.; Proud, D.; Kagey-Sobotka, A.; Adkinson, N.F.; Friedhof, L.; Naclerio, R.M.; Lichtenstein, L.M. J. Allergy Clin. Immunol., 1989, 84, 197-205.
88. Bousquet, J. Allergy, 2005, 60, 1-3.
89. Pierkes, M.; Bellinghausen, I.; Hultsch, T.; Metz, G.; Knop, J.; Saloga, J. J. Allergy Clin. Immunol., 1999, 103, 326-332.
90. Marshall, J.S.; Leal-Berumen, I.; Nielsen, L.; Glibetic, M, Jordana, M. J. Clin. Invest., 1996, 97, 1122-1128.
91. Rak, S.; Lowhagen, O.; Venge, P. J. Allergy Clin. Immunol., 1988, 82, 470-480.
92. Rak, S.; Hakanson, L.; Venge, P. J. Allergy Clin. Immunol., 1990, 86, 706-713.
93. Bloemen, K.; Verstraelen, S.; van der Heuwel, R.; Witters, H.; Nelissen, I.; Schoeters, G. Immunol. Lett., 2007, 113, 6-18.
94. Fanta, C.; Bohle, B.; Hirt, W.; Siemann, U.; Horak, F.; Kraft, D.; Ebner, H.; Ebner, C. Int. Arch. Allergy Immunol., 1999, 120, 218-24.
95. Marcucci, F.; Sensi, L.; Frati, F.; Senna, G.E.; Canonica, G.W.; Parmiani, S.; Passalacqua, G. Allergy, 2001, 56, 1091-1095.
96. Passalacqua, G.; Albano, M.; Fregonese, L.; Riccio, A.; Pronzato, C.; Mela, G.S.; Canonica G.W. Lancet, 1998, 351, 629-632.
97. Marcucci, F.; Frati, F.; Bernardini, R.; Novembre, E.; Barbato, A.; Pecora, S. Allergy, 2003, 58, 657-662.
98. Silvestri, M.; Spallarossa, D.; Battistini, E.; Sabatini, F.; Pecora, S.; Parmiani, S.; Rossi G.A. J. Invest. Allergol. Clin. Immunol., 2002, 12, 52-59.
99. Passalacqua, G.; Albano, M.; Riccio, A.; Fregonese, L.; Puccinelli, P.; Parmiani, S.; Canonica, G.W. J. Allergy Clin. Immunol., 1999, 104, 964-968.
100. Marcucci F., Sensi, L.; Incorvaia, C.; Di Cara, G.; Moingeon, P.; Frati, F. Allergy, 2007, 62, 1475-1477.
101. Marcucci, F.; Incorvaia, C.; Sensi, L.; Di Cara, G.; Cadario, G.; Cavaliere, A.; Moingeon, P. Puccinelli, P.; Di Gioacchino, M.; Frati, F. Int. J. Immunopathol. Pharmacol., in press.
102. Gidaro, G.; Marcucci, F.; Sensi, L.; Incorvaia, C.; Frati, F.; Ciprandi, G. Clin. Exp. Allergy, 2005, 35, 565-571.