Metaanalysis of the efficacy of sublingual immunotherapy in the treatment of allergic asthma in pediatric patients, 3 to 18 years of age

Chest

Volumn 133, Issue 3, 2008, Pages 599-609

  Penagos, Martin ^a   Passalacqua, Giovanni ^a   Compalati, Enrico ^a   Baena Cagnani, Carlos E ^b   Orozco, Socorro ^c   Pedroza, Alvaro ^c   Canonica, Giorgio Walter ^a,d  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF CÓRDOBA   (Spain)

^c INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^d Allergy and Respiratory Diseases   (Italy)

Author keywords

Asthma; Children; Efficacy; Metaanalysis; Randomized controlled trials; Sublingual immunotherapy

Indexed keywords

ALLERGEN; PLACEBO;

ADVERSE OUTCOME; ALLERGIC ASTHMA; ALLERGIC CONJUNCTIVITIS; ALLERGIC RHINITIS; ARTICLE; CLINICAL TRIAL; COCHRANE LIBRARY; COMPUTER PROGRAM; CONFIDENCE INTERVAL; DRUG EFFICACY; DRUG OVERDOSE; DRUG TOLERABILITY; ELECTRONIC MEDICAL RECORD; EYE DISEASE; GASTROINTESTINAL SYMPTOM; HUMAN; IMMUNOTHERAPY; META ANALYSIS; MOUTH DISEASE; NOSE DISEASE; PRIORITY JOURNAL; QUALITY CONTROL; RANDOMIZATION; SCORING SYSTEM; SUBLINGUAL IMMUNOTHERAPY; SYSTEMATIC REVIEW;

EID: 40549140165     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.06-1425     Document Type: Article

References (75)

1. Bousquet J Lockey RF Malling HJ WHO position paper: allergen immunotherapy: therapeutic vaccines for allergic diseases Allergy 53 1998 1 42
2. Moller C Dreborg S Ferdousi HA Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study) J Allergy Clin Immunol 109 2002 251 256
3. Bernstein DI Wanner M Borish L Twelve-year survey of fatal reactions to allergen injections and skin testing: 1990–2001 J Allergy Clin Immunol 113 2004 1129 1136
4. Passalacqua G Guerra L Pasquali M Efficacy and safety of sublingual immunotherapy Ann Allergy Asthma Immunol 93 2004 3 12
5. Bousquet J Van Cauwenberge P Allergic rhinits and its impact on asthma J Allergy Clin Immunol 108 2001 S146 S150
6. Di Rienzo V Minelli M Musarra A Post-marketing survey on the safety of sublingual immunotherapy in children below the age of 5 years Clin Exp Allergy 35 2005 560 564
7. Khinchi MS Poulsen LK Carat F Clinical efficacy of sublingual and subcutaneous birch pollen allergen-specific immunotherapy: a randomized, placebo-controlled, double-blind, double-dummy study Allergy 59 2004 45 53
8. Quirino T Iemoli E Siciliani E Sublingual versus injective immunotherapy in grass pollen allergic patients: a double blind (double dummy) study Clin Exp Allergy 26 1996 1253 1261
9. Cosmi L Santarlasci V Angeli R Sublingual immunotherapy with Dermatophagoides monomeric allergoid down-regulates allergen-specific immunoglobulin E and increases both interferon γ and interleukin 10 production Clin Exp Allergy 36 2006 261 272
10. Ciprandi G Fenoglio D Cirillo I Sublingual immunotherapy and regulatory T cells Allergy 61 2006 511 513
11. Abramson, MJ, Puy, RM, Weiner, JM, . Allergen immunotherapy for asthma. Cochrane Database Syst Rev (database online). Issue 4, 2003
12. Wilson DR Torres-Lima M Durham SR Sublingual immunotherapy for allergic rhinitis: systematic review and metaanalysis Allergy 60 2005 4 12
13. Penagos M Compalati E Tarantini F Efficacy of sublingual immunotherapy in the treatment of allergic rhinitis in pediatric patients 3 to 18 years of age: a meta-analysis of randomized, placebo-controlled and double-blind trials Ann Allergy Asthma Immunol 97 2006 141 148
14. Moher D Cook DJ Eastwood S Improving the quality of reports of meta-analyses of randomised controlled trials: the QUORUM statement: quality of reporting meta-analysis Lancet 354 1999 1896 1900
15. Alderson, P, Green, S, . Cochrane Collaboration open learning material for reviewers: version 1.1, 2002. Available at: www.cochrane-net.org/openlearning. Accessed December 28, 2007
16. Robinson KA Dickersin K Development of a highly sensitive search strategy for the retrieval of reports of controlled trials using PubMed Int J Epidemiol 31 2002 150 153
17. American Academy of Pediatrics Council on child health: age limits of pediatrics Pediatrics 49 1972 463
18. Litt IF Age limits of pediatrics, American Academy of Pediatrics, Council on Child Health, Pediatrics, 1972;49:463 Pediatrics 102 1998 249 250
19. Dawson B Research questions about one group Dawson B Basic & clinical biostatistics 4th ed. 2004 McGraw-Hill Medical New York, NY 118
20. Jadad AR Moore RA Carroll D Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17 1996 1 12
21. Moher D Cook DJ Jadad AR Assessing the quality of randomized controlled trials: implications for the conduct of meta-analyses Health Technol Assess 3 1999 i iv 1–98
22. Viera AJ Garrett JM Understanding interobserver agreement: the kappa statistic Fam Med 37 2005 360 363
23. Bland JM Altman DG Statistical methods for assessing agreement between two methods of clinical measurement Lancet 1 1986 307 310
24. MedCalc Software MedCalc for Windows, version 8.1.1 2006 MedCalc Software Mariakerke, Belgium
25. Bormann DigitizeIt 1.5.7 program 2003 Bormann Braunschweig, Germany
26. Deeks JJ Altman D Bradburn MJ Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis Egger M Davey Smith G Altman DG Systematic reviews in health care 2001 BMJ Publishing London, UK 285 312
27. Higgins JP Thompson SG Deeks JJ Measuring inconsistency in meta-analyses BMJ 327 2003 557 560
28. DerSimonian R Laird N Meta-analysis in clinical trials Control Clin Trials 7 1986 177 188
29. Higgins, JPT, Green, S, eds. Formulating the problem: Cochrane handbook for systematic reviews of interventions 4.2.6 [updated September 2006]. Cochrane Database Syst Rev (database online). Issue 4, 2006
30. Sutton AJ Higgins JP Recent developments in meta-analysis Stat Med 27 2007 625 659
31. Wang MC Bushman BJ Using the normal quantile plot to explore meta-analytic data sets Psychol Methods 3 1998 46 54
32. Cochrane Collaboration RevMan analyses, Version 1.0 for Windows Review manager (RevMan) 4.2 2002 The Cochrane Collaboration Oxford, UK
33. SPSS, Inc. SPSS version 14.0 for Windows. SPSS Inc. Chicago, IL:
34. Tari MG Mancino M Monti G Efficacy of sublingual immunotherapy in patients with rhinitis and asthma due to house dust mite: a double-blind study Allergol Immunopathol (Madr) 18 1990 277 284
35. Hirsch T Sähn M Leupold W Double-blind placebo-controlled study of sublingual immunotherapy with house dust mite extract (D.pt.) in children Pediatr Allergy Immunol 8 1997 21 27
36. Vourdas D Syrigou E Potamianou P Double-blind placebo-controlled evaluation of sublingual-swallow immunotherapy with standardized olive pollen extract in pediatric patients with allergic rhinoconjunctivitis and mild asthma due a olive pollen sensitization Allergy 53 1998 662 672
37. Caffarelli C Sensi LG Marcucci F Preseasonal local allergoid immunotherapy to grass pollen in children: a double-blind, placebo-controlled, randomized trial Allergy 55 2000 1142 1147
38. Pajno GB Morabito L Barberio G Clinical and immunologic effects of long-term sublingual immunotherapy in asthmatic children sensitized to mites: a double-blind, placebo-controlled study Allergy 55 2000 842 849
39. Bahçeciler NN Isik U Barlan IB Efficacy of sublingual immunotherapy in children with asthma and rhinitis: a double-blind, placebo-controlled study Pediatr Pulmonol 32 2001 49 55
40. Ippoliti F De Sanctis W Volterrani A Immunomodulation during sublingual therapy in allergic children Pediatr Allergy Immunol 14 2003 216 221
41. Rolinck-Werninghaus C Wolf H Liebke C A prospective, randomized, double-blind, placebo-controlled multi-centre study on the efficacy and safety of sublingual immunotherapy (SLIT) in children with seasonal allergic rhinoconjunctivitis to grass pollen Allergy 59 2004 1285 1293
42. Niu CK Chen WY Huang JL Efficacy of sublingual immunotherapy with high-dose mite extracts in asthma: a multi-center, double-blind, randomized, and placebo-controlled study in Taiwan Respir Med 100 2006 1374 1383
43. Akobeng AK Principles of evidence based medicine Arch Dis Child 90 2005 837 840
44. Sackett DL Clinical epidemiology. what, who, and whither J Clin Epidemiol 55 2002 1161 1166
45. Shekelle PG Woolf SH Eccles M Clinical guidelines: developing guidelines BMJ 318 1999 593 596
46. Egger M Smith GD Phillips AN Meta-analysis: principles and procedures BMJ 315 1997 1533 1537
47. Egger M Juni P Bartlett C How important are comprehensive literature searches and the assessment of trial quality in systematic reviews? Empirical study Health Technol Assess 7 2003 1 76
48. Passalacqua G Canonica GW Sublingual immunotherapy: update 2006 Curr Opin Allergy Clin Immunol 6 2006 449 454
49. Cox LS Larenas-Linnemann D Nolte H Sublingual immunotherapy: a comprehensive review J Allergy Clin Immunol 117 2006 1021 1035
50. Holmgren J Czerkinsky C Mucosal immunity and vaccines Nat Med 11 2005 S45 S53
51. Olaguíbel JM álvarez-Puebla MJ Efficacy of sublingual allergen vaccination for respiratory allergy in children: conclusions from one meta-analysis J Investig Allergol Clin Immunol 15 2005 9 16
52. Calamita Z Saconato H Pelà AB Efficacy of sublingual immunotherapy in asthma: systematic review of randomized-clinical trials using the Cochrane Collaboration method Allergy 61 2006 1162 1172
53. Camara-Clark OA Araujo-Castro A Searching the Literatura Latino Americana e do Caribe em Ciências da Saúde (LILACS) database improves systematic reviews Int J Epidemiol 31 2002 112 114
54. Higgins J Thompson S Deeks J Statistical heterogeneity in systematic reviews of clinical trials: a critical appraisal of guidelines and practice J Health Serv Res Policy 7 2002 51 61
55. Sterne JAC Egger M Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis J Clin Epidemiol 54 2001 1046 1055
56. Fiocchi A Pajno G La Grutta S Safety of sublingual-swallow immunotherapy in children aged 3 to 7 years Ann Allergy Asthma Immunol 95 2005 254 258
57. Di Rienzo V Pagani A Parmiani S Post-marketing surveillance study on the safety of sublingual immunotherapy in children Allergy 54 1999 1110 1113
58. Gidaro GB Marcucci F Sensi L The safety of sublingual-swallow immunotherapy: an analysis of published studies Clin Exp Allergy 35 2005 565 571
59. Dahl R Stender A Rak S Specific immunotherapy with SQ standardized grass allergen tablets in asthmatics with rhinoconjunctivitis Allergy 61 2006 185 190
60. Kleine-Tebbe J Ribel M Herold DA Safety of a SQ-standardised grass allergen tablet for sublingual immunotherapy: a randomized, placebo-controlled trial Allergy 61 2006 181 184
61. Durham SR Yang WH Pedersen MR Sublingual immunotherapy with once-daily grass allergen tablets: a randomized controlled trial in seasonal allergic rhinoconjunctivitis J Allergy Clin Immunol 117 2006 802 809
62. Laczo RM Sackett PR Bobko P A comment on sampling error in the standardized mean difference with unequal sample sizes: avoiding potential errors in meta-analytic and primary research J Appl Psychol 90 2005 758 764
63. Stenning SP Parmar MK Designing randomised trials: both large and small trials are needed Ann Oncol 13S 2002 131 138
64. Battle MV Cowan GS Rakow EA Statistical power: planning for it, estimating it post hoc, and reporting it IEEE Trans Prof Commun 43 2000 345 354
65. Cohn LD Becker BJ How meta-analysis increases statistical power Psychol Methods 8 2003 243 253
66. Rodríguez-Santos O Inmunoterapia sublingual con extracto alergénico de Dermatophagoides pteronyssinus en niños con asma Rev Alerg Mex 51 2004 177 180
67. Bufe A Ziegler-Kirbach E Stoeckmann E Efficacy of sublingual swallow immunotherapy in children with severe grass pollen allergic symptoms: a double-blind placebo-controlled study Allergy 59 2004 498 504
68. Velarde-Domínguez T Talavera-Hernández O Sánchez-Santa Ana JR Eficacia clínica y seguridad de la inmunoterapia sublingual con extractos estandarizados en el tratamiento del asma alérgica ocasionada por Dermatophagoides en población mexicana pediátrica Rev Sanid Milit 56 2002 10 14
69. CONSORT Group Improving the quality of reporting of randomized controlled trials: the CONSORT statement JAMA 276 1996 637 639
70. !!! US Food and Drug Administration. Guidance for industry: allergic rhinitis; clinical development programs for drug products. Available at: http://www.fda.gov/cder/guidance/2718dft.htm. Accessed December 28, 2007
71. Cohen J Statistical power analysis for the behavioral sciences 2nd ed. 1988 Lawrence Erlbaum Associates Hillsdale, NJ
72. DerSimonian R Kacker R Random-effects model for meta-analysis of clinical trials: an update Contemp Clin Trials 28 2007 105 114
73. Dupont, WD, Plummer WD Jr. PS power and sample size calculator, version 2.1.31. Available at: http://biostat.mc.vanderbilt.edu/twiki/bin/view/Main/PowerSampleSize. Accessed January 22, 2008
74. Moher D Dulberg CS Wells GA Statistical power, sample size, and their reporting in randomized controlled trials JAMA 272 1994 122 124
75. Canonica GW Baena-Cagnani CE Bousquet J Recommendations for standardization of clinical trials with allergen specific immunotherapy for respiratory allergy: a statement of a World Allergy Organization (WAO) taskforce Allergy 62 2007 317 324