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Volumn 27, Issue 4, 2010, Pages 665-672

Basolateral efflux mediated by multidrug resistance-associated protein 3 (Mrp3/Abcc3) facilitates intestinal absorption of folates in mouse

Author keywords

Abc transporters; Active transport; Intestinal absorption; M.RP3; Serosal efflux

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; CYANOCOBALAMIN; FOLIC ACID; FOLINIC ACID; HOMOCYSTEINE; MULTIDRUG RESISTANCE PROTEIN 3; 5-METHYLTETRAHYDROFOLATE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 3; TETRAHYDROFOLIC ACID DERIVATIVE;

EID: 77953160743     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-0047-4     Document Type: Article
Times cited : (23)

References (28)
  • 1
    • 0031866357 scopus 로고    scopus 로고
    • Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats
    • Hirohashi T, Suzuki H, Ito K, Ogawa K, Kume K, Shimizu T, et al. Hepatic expression of multidrug resistance-associated proteinlike proteins maintained in eisai hyperbilirubinemic rats. Mol Pharmacol. 1998;53:1068-1075 (Pubitemid 28280450)
    • (1998) Molecular Pharmacology , vol.53 , Issue.6 , pp. 1068-1075
    • Hirohashi, T.1    Suzuki, H.2    Ito, K.3    Ogawa, K.4    Kume, K.5    Shimizu, T.6    Sugiyama, Y.7
  • 2
    • 33644910207 scopus 로고    scopus 로고
    • Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides
    • Zelcer N, van de Wetering K, de Waart R, Scheffer GL, Marschall HU, Wielinga PR, et al. Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides. J Hepatol. 2006;44:768-775
    • (2006) J Hepatol. , vol.44 , pp. 768-775
    • Zelcer, N.1    Van De Wetering, K.2    De Waart, R.3    Scheffer, G.L.4    Marschall, H.U.5    Wielinga, P.R.6
  • 3
    • 0034928631 scopus 로고    scopus 로고
    • Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver
    • DOI 10.1053/jhep.2001.26213
    • Donner MG, Keppler D. Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver. Hepatology. 2001;34:351-359 (Pubitemid 32702348)
    • (2001) Hepatology , vol.34 , Issue.2 , pp. 351-359
    • Donner, M.G.1    Keppler, D.2
  • 4
    • 21044435938 scopus 로고    scopus 로고
    • Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception
    • Zelcer N, van de Wetering K, Hillebrand M, Sarton E, Kuil A, Wielinga PR, et ai Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception. Proc Natl. Acad Sd USA. 2005;102:7274-7279
    • (2005) Proc Natl. Acad Sd USA , vol.102 , pp. 7274-7279
    • Zelcer, N.1    Van De Wetering, K.2    Hillebrand, M.3    Sarton, E.4    Kuil, A.5    Wielinga, P.R.6
  • 5
    • 0034665559 scopus 로고    scopus 로고
    • Specific detection of multidrug resistance proteins MRPl, MR.P2, MR.P3, MR.P5, and MDR.3 P-glycoprotein with, a panel of monoclonal antibodies
    • Scheffer GL, Kool M, Heijn M, de Haas M, Pijnenborg AC, Wijnholds J, et ai Specific detection of multidrug resistance proteins MRPl, MR.P2, MR.P3, MR.P5, and MDR.3 P-glycoprotein with, a panel of monoclonal antibodies. Cancer Res. 2000;60:5269-5277
    • (2000) Cancer Res. , vol.60 , pp. 5269-5277
    • Scheffer, G.L.1    Kool, M.2    Heijn, M.3    De Haas, M.4    Pijnenborg, A.C.5    Wijnholds, J.6
  • 6
    • 66449128354 scopus 로고    scopus 로고
    • In vitro-in vivo extrapolation of transporter-mediated clearance in the liver and kidney
    • Kusuhara H, Sugiyama Y. In vitro-in vivo extrapolation of transporter-mediated clearance in the liver and kidney. Drug Metab Pharmacokinet. 2009;24:37-52.
    • (2009) Drug Metab Pharmacokinet. , vol.24 , pp. 37-52
    • Kusuhara, H.1    Sugiyama, Y.2
  • 7
    • 54349088976 scopus 로고    scopus 로고
    • Increasing systemic exposure of methotrexate by active efflux mediated by multidrug resistance-associated protein 3 (mrp3/ abcc3)
    • Kitamura Y, Hirouchi M, Kusuhara H, Schuetz JD, Sugiyama Y. Increasing systemic exposure of methotrexate by active efflux mediated by multidrug resistance-associated protein 3 (mrp3/ abcc3). J Pharmacol Exp Ther. 2008;327:465-473
    • (2008) J Pharmacol Exp Ther. , vol.327 , pp. 465-473
    • Kitamura, Y.1    Hirouchi, M.2    Kusuhara, H.3    Schuetz, J.D.4    Sugiyama, Y.5
  • 10
    • 0034723163 scopus 로고    scopus 로고
    • ATP-dependent transport of bile salts by rat multidrug resistance- Associated protein 3 (Mrp3)
    • DOI 10.1074/jbc.275.4.2905
    • Hirohashi T, Suzuki H, Takikawa H, Sugiyama Y. ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3). J Biol Chem. 2000;275:2905-2910 (Pubitemid 30082066)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.4 , pp. 2905-2910
    • Hirohashi, T.1    Suzuki, H.2    Takikawa, H.3    Sugiyama, Y.4
  • 12
    • 33745764557 scopus 로고    scopus 로고
    • Efflux mechanism of taurocholate across the rat intestinal basolateral membrane
    • DOI 10.1021/mp050101+
    • Sakamoto S, Suzuki H, Kusuhara H, Sugiyama Y. Efflux mechanism, of taurocholate across the rat intestinal basolateral. membrane. Mol Pharm. 2006;3:275-281 (Pubitemid 44021433)
    • (2006) Molecular Pharmaceutics , vol.3 , Issue.3 , pp. 275-281
    • Sakamoto, S.1    Suzuki, H.2    Kusuhara, H.3    Sugiyama, Y.4
  • 13
    • 0035476729 scopus 로고    scopus 로고
    • Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: Effect of polyglutamylation on MTX transport
    • Zeng H, Chen ZS, Belinsky MG, Rea PA, Kruh GD. Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res. 2001;61:7225-7232 (Pubitemid 32946519)
    • (2001) Cancer Research , vol.61 , Issue.19 , pp. 7225-7232
    • Zeng, H.1    Chen, Z.-S.2    Belinsky, M.G.3    Rea, P.A.4    Kruh, G.D.5
  • 14
    • 14044262904 scopus 로고    scopus 로고
    • Structure and regulation of the murine reduced folate carrier gene: Identification of four noncoding exons and promoters and regulation by dietary folates
    • DOI 10.1074/jbc.M412662200
    • Liu. M, Ge Y, Cabelof DC, Aboukameel A, Heydari AR, Mohammad R, et al. Structure and regulation of the murine reduced, folate carrier gene: identification of four noncoding exons and promoters and regulation by dietary folates. J Biol Chem. 2005;280:5588-5597 (Pubitemid 40280037)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.7 , pp. 5588-5597
    • Liu, M.1    Ge, Y.2    Cabelof, D.C.3    Aboukameel, A.4    Heydari, A.R.5    Mohammad, R.6    Matherly, L.H.7
  • 15
    • 33751244559 scopus 로고    scopus 로고
    • Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
    • DOI 10.1016/j.cell.2006.09.041, PII S009286740601347X
    • Qiu A, Jansen M, Sakaris A, Min SH, Chattopadhyay S, Tsai E, et al. Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell. 2006;127:917-928 (Pubitemid 44792250)
    • (2006) Cell , vol.127 , Issue.5 , pp. 917-928
    • Qiu, A.1    Jansen, M.2    Sakaris, A.3    Min, S.H.4    Chattopadhyay, S.5    Tsai, E.6    Sandoval, C.7    Zhao, R.8    Akabas, M.H.9    Goldman, I.D.10
  • 17
    • 0023433357 scopus 로고
    • A carrier-mediated transport for folate in basolateral membrane vesicles of rat small intestine
    • Said HM, Redha R. A carrier-mediated transport for folate in basolateral membrane vesicles of rat small intestine. Biochem J. 1987;247:141-146
    • (1987) Biochem J , vol.247 , pp. 141-146
    • Said, H.M.1    Redha, R.2
  • 18
    • 34249095550 scopus 로고    scopus 로고
    • Regional expression and activity of breast cancer resistance protein (Bcrp/Abcg2) in mouse intestine: Overlapping distribution with sulfotransferases
    • DOI 10.1124/dmd.106.011239
    • Enokizono J, Kusuhara H, Sugiyama Y. Regional expression and activity of breast cancer resistance protein (Bcrp/Abcg2) in. mouse intestine: overlapping distribution with sulfotransferases. Drug Metab Dispos. 2007;35:922-928 (Pubitemid 46798603)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.6 , pp. 922-928
    • Enokizono, J.1    Kusuhara, H.2    Sugiyama, Y.3
  • 20
    • 0031909632 scopus 로고    scopus 로고
    • Comparison of intestinal folate carrier clone expressed in IEC-6 cells and in Xenopus oocytes
    • Kumar CK, Nguyen TT, Gonzales FB, Said HM. Comparison of intestinal folate carrier clone expressed in IEC-6 cells and in Xenopus oocytes. Am J Physiol. 1998;274:C289-94.
    • (1998) Am J Physiol. , vol.274
    • Kumar, C.K.1    Nguyen, T.T.2    Gonzales, F.B.3    Said, H.M.4
  • 21
    • 34547138910 scopus 로고    scopus 로고
    • Functional characterization of human proton-coupled folate transporter/lieme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter
    • Nakai Y, Inoue K, Abe N, Hatakeyama M, Ohta KY, Otagiri M, et ai Functional characterization of human proton-coupled folate transporter/lieme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter. J Pharmacol Exp Ther. 2007;322:469-476
    • (2007) J Pharmacol Exp Ther. , vol.322 , pp. 469-476
    • Nakai, Y.1    Inoue, K.2    Abe, N.3    Hatakeyama, M.4    Ohta, K.Y.5    Otagiri, M.6
  • 22
    • 34548026299 scopus 로고    scopus 로고
    • The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorption
    • DOI 10.1182/blood-2007-02-077099
    • Zhao R, Min SH, Qiu A, Sakaris A, Goldberg GL, Sandoval C, et al. The spectrum of mutations in the PCFT gene, coding for an. intestinal folate transporter, that are the basis for hereditary folate malabsorption. Blood. 2007;110:1147-1152 (Pubitemid 47281410)
    • (2007) Blood , vol.110 , Issue.4 , pp. 1147-1152
    • Zhao, R.1    Sang, H.M.2    Qiu, A.3    Sakaris, A.4    Goldberg, G.L.5    Sandoval, C.6    Malatack, J.J.7    Rosenblatt, D.S.8    Goldman, I.D.9
  • 25
    • 25144450046 scopus 로고    scopus 로고
    • Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport
    • DOI 10.1007/s11095-005-6810-2
    • Ito K, Suzuki H, Horie T, Sugiyama Y. Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport. Pharm Res. 2005;22:1559-1577 (Pubitemid 41355896)
    • (2005) Pharmaceutical Research , vol.22 , Issue.10 , pp. 1559-1577
    • Ito, K.1    Suzuki, H.2    Horie, T.3    Sugiyama, Y.4
  • 26
    • 33751199707 scopus 로고    scopus 로고
    • Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/and Abcc4-/- Mice
    • Zamek-Gliszczynski MJ, Nezasa K, Tian X, Bridges AS, Lee K, Belinsky MG, et al. Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/and Abcc4-/- mice. J Pharmacol Exp Ther. 2006;319:1485-1491
    • (2006) J Pharmacol Exp Ther. , vol.319 , pp. 1485-1491
    • Zamek-Gliszczynski, M.J.1    Nezasa, K.2    Tian, X.3    Bridges, A.S.4    Lee, K.5    Belinsky, M.G.6
  • 27
    • 76749106997 scopus 로고    scopus 로고
    • Functional characterization of multidrug resistance-associated protein 3 (Mrp3/ Abcc3) in the basolateral efflux of glucuronide conjugates in the mouse small intestine
    • in press
    • Kitamura Y, Kusuhara H, Sugiyama Y. Functional characterization of multidrug resistance-associated protein 3 (Mrp3/ Abcc3) in the basolateral efflux of glucuronide conjugates in the mouse small intestine. J Pharmacol Exp Ther, in press.
    • J Pharmacol Exp Ther
    • Kitamura, Y.1    Kusuhara, H.2    Sugiyama, Y.3


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