Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 319, Issue 3, 2006, Pages 1485-1491

  Zamek Gliszczynski, Maciej J ^a,c   Nezasa, Ken Ichi ^a,d   Tian, Xianbin ^a   Bridges, Arlene S ^a   Lee, Kun ^b   Belinsky, Martin G ^b   Kruh, Gary D ^b   Brouwer, Kim L R ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b FOX CHASE CANCER CENTER   (United States)

^c ELI LILLY AND COMPANY   (United States)

^d SHIONOGI AND CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; GLUCURONIDE; HARMOL; HYMECROMONE; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; PARACETAMOL; SULFATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG STRUCTURE; GENE CASSETTE; LIVER; MALE; MEDICAL LITERATURE; MEDICAL RESEARCH; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE; BLOTTING, WESTERN; GLUCURONIDES; HARMINE; HYMECROMONE; LIVER; MICE; MICE, KNOCKOUT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEINS; SULFATES;

EID: 33751199707     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.110106     Document Type: Article

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