Increased expression of brain-derived neurotrophic factor but not neurotrophin-3 mRNA in rat brain after cortical impact injury

Journal of Neuroscience Research

Volumn 44, Issue 2, 1996, Pages 157-164

  Yang, K ^a   Perez Polo, J R ^b   Mu, X S ^a   Yan, H Q ^a   Xue, J J ^a   Iwamoto, Y ^a   Liu, S J ^a   Dixon, C E ^a   Hayes, R L ^a,c  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

BDNF; gene expression; neurotrophin; NT3; traumatic brain injury

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; NEUROTROPHIN 3;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX LESION; CONTROLLED STUDY; GENE EXPRESSION; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RNA PROBE;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN INJURIES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL CORTEX; DENTATE GYRUS; FUNCTIONAL LATERALITY; HIPPOCAMPUS; MALE; MUSCLE TONUS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEUROTROPHIN 3; ORGAN SPECIFICITY; POSTURE; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0029965072     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19960415)44:2<157::AID-JNR8>3.0.CO;2-C     Document Type: Article

References (55)

1. Anderson RF, Alterman AL, Barde YA, Lindsay RM (1990): Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture. Neuron 5:297-306.
2. Ballarin M, Ernfors P, Lindefors N, Persson H (1991): Hippocampal damage and kainic acid injection induce a rapid increase in mRNA for BDNF and NGF in the rat brain. Exp Neurol 114: 35-43.
3. Barde YA, Edgar D, Thoenen H (1980): Sensory neurons in culture: Changing requirement for survival factors during embryonic development. Proc Natl Acad Sci USA 77:1199-1230.
4. Bessho Y, Nakanishi S, Hiroyuki H, Nawa H (1993): Glutamate receptor agonists enhance the expression of BDNF mRNA in cultures of cerebellar granule cells. Mol Brain Res 18:201-208.
5. Collazo D, Takahashi H. McKay RDG (1992): Cellular target and trophic functions of neurotrophin-3 in the developing rat hippocampus. Neuron 9:643-656.
6. Davies AM, Thoenen H, Bard YA (1986): The response of chick sensory neurons to brain-derived neurotrophic factor. J Neurosci 6:1897-1904.
7. DiStefano PS, Friedman B, Radziejewski C, Alexandere, Boland P, Schick CM, Lindsay RM, Wiegand SJ (1992): The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons. Neuron 8:983-993.
8. Dixon CE, Lyeth BG, Povlishock JT, Findling RL, Hamm RJ, Marmarou A, Young HF, Hayes RL (1987): A fluid percussion model of experimental brain injury in the rat. J Neurosurg 67:110-119.
9. Dixon CE. Clifton GL, Lighthall JW, Yaghmai AA, Hayes RL (1991): A controlled cortical impact model of traumatic brain injury in the rat. J Neurosci Methods 39:253-262.
10. Ernfors P, Wetmore C, Olson L, Persson H (1990): Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family. Neuron 5:511-526.
11. Ernfors P, Bengzon J, Persson H, Lindvall O (1991): Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis. Neuron 7:165-176.
12. Faden AI, Demediuk P, Panter SS, Vink R (1989): The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 244:798-800.
13. 45Ca autoradiographic study. Brain Res 624:94-102.
14. Friedman WJ, Ernfors P, Persson H (1991): Transient and persistent expression of NT-3/BDNF mRNA in the rat brain during postnatal development. J Neurosci 11:1577-1584.
15. Gall CM, Isackson PJ (1989): Limbic seizures increase neuronal production of messenger RNA for nerve growth factor. Science 245:758-761.
16. Gall C, Lauterborn J (1992): The dentate gyrus: A model system for studies of neurotrophin regulation. Epilepsy Res [Suppl] 7:171-185.
17. Gall C, Lauterborn J, Bundman M, Murray K, Isackson P (1991a): Seizures and the regulation of neurotrophic factor and neuropeptide gene expression in brain. Epilepsy Res [Suppl] 4:225-245.
18. Gall C, Murray K, Isackson P (1991b): Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus. Mol Brain Res 9:113-123.
19. Ghosh A, Carnahan J, Greenberg ME (1994): Requirement for BDNF in activity-dependent survival of cortical neurons. Science 263: 1618-1623.
20. Hayes RL, Jenkins LW, Lyeth BG (1992): Neuropharmacological mechanisms of traumatic brain injury: Acerylcholine and excitatory amino acids. J Neurotrauma [Suppl] 9:173-187.
21. Hofer M, Pagliusi SR, Hohn A, Leibrock J, Barde YA (1990): Regional distribution of brain-derived neurotrophic factor mRNA. EMBO J 19:2459-2464.
22. Hohn A, Leibrock J, Bailey K, Bard YA (1990): Identification and characterization of a novel member of the nerve growth factor/ brain-derived neurotrophic factor family. Nature 344:339-341.
23. Hyman C, Hofer M, Barde YA, Juhasz M, Yancopoulos GD, Squinto SP, Lindsay RM (1991): BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature 350:230-232.
24. Ip NY, Li Y, Yancopoulos GD, Lindsay RM (1993): Cultured hippocampal neurons show response to BDNF, NT-3, and NT-4, but not NGF. J Neurosci 13:3394-3405.
25. Isackson PJ, Huntsman MM, Murray MD, Gall CM (1991): BDNF mRNA expression is increased in adult rat forebrain after lim-bic seizures: Temporal patterns of induction distinct from NGF. Neuron 6:937-948.
26. Jenkins LW, Moszynski K, Lyeth BG, Lewelt W, De Witt DS. Allen A, Dixon CE, Povlishock JT, Majewski TJ, Clifton GL, Young HF, Becker DP. Hayes RL (1989): Increased vulnerability of the mildly traumatized brain to cerebral ischemia: The use of controlled secondary ischemia as a research tool to identify common or different mechanisms contributing to mechanical and ischemic brain injury. Brain Res 477:211-224.
27. Katayama Y, Becker DP, Tamura T, Hovda DA (1990): Massive increases extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J Neurosurg 73:889-900.
28. Knüsel B, Winslow JW, Rosenthal A, Burton L.F., Seid DP, Nikolics K, Hefti F (1991): Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin-3. Proc Natl Acad Sci USA 88: 961-965.
29. Knüsel B, Winslow JW, Rosenthal A, Burton LE, Beck KD, Rabin S, Nikolics K, Hefti F (1992): K-252b selectively potentiates cellular actions and trk tyrosine phosphorylation mediated by neurotrophin-3. J Neurochem 59:715-722.
30. Kokaia Z, Gunilla G, Ringstedt T, Bengzon J, Kokaia M, Siesjo BK, Persson H, Lindvall O (1993): Rapid increase of BDNF mRNA levels in cortical neurons following spreading depression: Regulation by glutamatergic mechanism independent of seizure activity. Mol Brain Res 19:277-286.
31. Lindsay RM, Thoenen H, Barde YA (1985): Placode and neural crestderived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor. Dev Biol 112:319-328.
32. Lindvall O, Ernfors P, Bengzon J, Kokaia Z, Smith ML, Siesjo BK, Persson H (1992): Differential regulation of mRNAs for nerve growth factor, brain derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc Natl Acad Sci USA 89:648-652.
33. Lowenstein DH, Thomas MJ, Smith DH, McIntosh TK (1992): Selective vulnerability of dentate hilar interneurons following traumatic brain injury. J Neurosci 12:4846-4853.
34. Lu B, Yokoyama M, Dreyfus CF, Black IB (1991): Depolarizating stimuli regulate nerve growth factor gene expression in cultures hippocampal neurons. Proc Natl Acad Sci USA 88:6289-6292.
35. Lyeth BG, Jenkins LW, Hamm RJ, Dixon CE, Phillips LL, Clifton GL, Young HF, Hayes RL (1990): Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat. Brain Res 526:249-258.
36. Maisonpierre PC, Belluscio L, Squinto S, Ip NY, Furth ME, Lindsay RM, Yancopoulos GD (1990): Neurotrophin-3: A neurotrophic factor related to NGF and BDNF. Science 247:1446-1451.
37. McIntosh TK (1993): Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: A review. J Neurotrauma 10:215-261.
38. Phillips LL, Belardo ET (1992): Expression of c-fos in the hippocampus following mild and moderate fluid percussion brain injury. J Neurotrauma 9:323-333.
39. Posmantur R, Hayes RL, Dixon CE, Taft WC (1994): Neurofilament 68 and neurofilament 200 protein levels decrease after traumatic brain injury (TBI). J Neurotrauma 11:533-545.
40. Prasad MR, Dhillon HS, Dempsey, Scheff SW (1994): Enhanced phosphodiestric breakdown of phosphatidylinositol biphosphate after experimental brain injury. J Neurochem 63:773-776.
41. Rocamora N, Palacios JM, Mengod G (1992): Limbic seizures induce a differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3, in the rat hippocampus. Mol Brain Res 13:27-33.
42. Simmons DM, Arriza JL, Swanson LW (1989): A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabeled single-stranded RNA probes. J Histotech 12:169-181.
43. Smith DH, Okiyama K, Thomas MJ, McIntosh TK (1993): Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury. J Neurosci 13: 5383-5392.
44. Smith MA, Makino S, Kvetnansky R, Post RM (1995): Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J Neurosci 15:1768-1777.
45. Springer JE, Byoung JG, Sessler FM (1994): Neurotrophic factor mRNA expression in dentate gyrus is increased following in vivo stimulation of the angular bundle. Mol Brain Res 23:135-143.
46. Taft WC, Yang K, Dixon CE, Hayes RL (1992): Microtubule-associated protein 2 levels decrease in hippocampus following traumatic brain injury. J Neurotrauma 9:281-290.
47. Taft WC, Yang K, Dixon CE, Clifton GL, Hayes RL (1993): Hypothermia attenuates the loss of hippocampal microtubule-associated protein 2 (MAP2) levels following traumatic brain injury. J Cereb Blood Flow Metab 13:796-802.
48. Takeda A, Onodera H, Yamasaki Y, Furukawa K, Kogure K, Obinata M, Shibahara S (1992): Decreased expression of neurotrophin-3 mRNA in the rat hippocampus following transient forebrain ischemia. Brain Res 569:177-180.
49. Takeda A, Onodera H, Sugimoto A, Kogure K, Obinata M, Shibahara S (1993): Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurophin-3 in the rat hippocampus following transient forebrain ischemia. Neuroscience 55:23-31.
50. Wetmore C, Ernfors P, Persson H, Olson L (1990): Localization of brain-derived neurotrophic factor mRNA to neurons in the brain by in situ hybridization. Exp Neurol 109:141-152.
51. Yang K, Taft WC, Dixon CE, Todaro CA, Yu RK, Hayes RL (1993): Alterations of protein kinase C in rat hippocampus following traumatic brain injury. J Neurotrauma 10:287-295.
52. Yang K, Mu S, Xue JJ, Liu PK, Whitson J, Salminen A, Dixon CE, Hayes RL (1994): Increased expression of c-fos gene and AP-1 transcription factor after cortical impact injury in rodent model. Brain Res 664:141-147.
53. Yang K, Mu XS, Xue JJ, Perez-Polo JR, Hayes RL (1995): Regional and temporal profiles of c-fos and nerve growth factor mRNA expression in rat brain after lateral cortical impact injury. J Neurosci Res 42:571-578.
54. Zaal K, Gido G, Ringstedt T, Bengzon J, Kokaia M, Siesjo BK. Persson H, Lindvall O (1993): Rapid increase of BDNF mRNA levels in cortical neurons following spreading depression: Regulation by glutamatergic mechanism independent of seizure activity. Mol Brain Res 19:277-286.
55. Zafra F, Hengerer B, Leibrock J, Thoenen H, Lindholm D (1990). Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J 9:3545-3550.