Long-term hyperexcitability in the hippocampus after experimental head trauma

Annals of Neurology

Volumn 50, Issue 6, 2001, Pages 708-717

  Santhakumar, Vijayalakshmi ^a,b   Ratzliff, Anna D H ^a   Jeng, Jade ^a   Toth, Zsolt ^a   Soltesz, Ivan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; ELECTROPHYSIOLOGY; GRANULE CELL; HEAD INJURY; HIPPOCAMPUS; HISTOCHEMISTRY; MOSSY FIBER; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BICUCULLINE; CONVULSANTS; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; EPILEPSY, POST-TRAUMATIC; EVOKED POTENTIALS; HEAD INJURIES, CLOSED; HIPPOCAMPUS; HUMANS; MOSSY FIBERS, HIPPOCAMPAL; RATS; TIME FACTORS;

EID: 0035199223     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.1230     Document Type: Article

References (61)

1. Seizures after head trauma: A population study
2. A population-based study of seizures after traumatic brain injuries
3. The nature of posttraumatic epilepsy
4. Posttraumatic epilepsy risk factors: One-year prospective study after head injury
5. Epilepsy after penetrating head injury. I. Clinical correlates: A report of the Vietnam Head Injury Study
6. Posttraumatic epilepsy: Cellular mechanisms and implications for treatment
7. Traumatic brain injury in the rat: Characterization of a lateral fluid-percussion model
8. Selective vulnerability of dentate hilar neurons following traumatic brain injury: A potential mechanistic link between head trauma and disorders of the hippocampus
9. Instantaneous perturbation of dentate interneuronal networks by a pressure wave-transient delivered to the neocortex
10. Epilepsy and the temporal lobes. A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes
11. Granule cell hyperexcitability in the early posttraumatic rat dentate gyrus: The 'irritable mossy cell' hypothesis
12. Brain injury-induced enhanced limbic epileptogenesis: Anatomical and physiological parallels to an animal model of temporal lobe epilepsy
13. Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats
14. Chronic histopathological consequences of fluid-percussion brain injury in rats: Effects of posttraumatic hypothermia
15. Progressive atrophy and neuron death for one year following brain trauma in the rat
16. Chronic failure in the maintenance of long-term potentiation following fluid percussion injury in the rat
17. Mossy fiber synaptic reorganization in the epileptic human temporal lobe
18. Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy
19. Synaptic reorganization by mossy fibers in human epileptic fascia dentata
20. Ultrastructural localization of dynorphin in the dentate gyrus in human temporal lobe epilepsy: A study of reorganized mossy fiber synapses
21. Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats
22. Synaptic reorganization in the hippocampus induced by abnormal functional activity
23. Mossy fiber synaptic reorganization induced by kindling: Time course of development, progression, and permanence
24. Hippocampal mossy fiber sprouting and synapse formation after status epilepticus in rats: Visualization after retrograde transport of biocytin
25. Influence of the type of initial precipitating injury and at what age it occurs on course and outcome in patients with temporal lobe seizures
26. 2+ currents in hippocampal granule cells isolated from epilepsy patients is associated with mossy fiber sprouting
27. The potential role for reactive astrocytes in CNS reinnervation following experimental brain injury in rat
28. Traumatic brain injury produces loss of neurons in hilus and CA3 but no significant mossy fiber sprouting in the hippocampus
29. Patch-clamp recordings reveal powerful GABAergic inhibition in dentate hilar neurons
30. Generation and propagation of epileptiform discharges in a combined entorhinal cortex/hippocampal slice
31. Long-duration self-sustained epileptiform activity in the hippocampal-parahippocampal slice: A model of status epilepticus
32. Prolonged febrile seizures in the immature rat model enhance hippocampal excitability long term
33. Tonic inhibition originates from synapses close to the soma
34. Neuroprotection by propofol in acute mechanical injury: Role of GABAergic inhibition
35. Histochemical demonstration of heavy metals. A revised version of the sulphide silver method suitable for both light and electronmicroscopy
36. Distribution of GABAergic synapses and their targets in the dentate gyrus of rat: A quantitative immunoelectron microscopic analysis
37. Interneurons of the hippocampus
38. Regional and time dependent variations of low Mg2+ induced epileptiform activity in rat temporal cortex slices
39. Paired-pulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus
40. A receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons
41. Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites
42. Zinc-induced collapse of augmented inhibition by GABA in a temporal lobe epilepsy model
43. Inhibitory function in two models of chronic epileptogenesis
44. Traumatic brain injury: A silent epidemic
45. Head injuries: Costs and consequences
46. Valproate therapy for prevention of posttraumatic seizures: A randomized trial
47. Clinical trials for seizure prevention
48. Tetrodotoxin prevents posttraumatic 1epileptogenesis in rats
49. Axonal sprouting in layer V pyramidal neurons of chronically injured cerebral cortex
50. Traumatic brain injury (TBI) induces sprouting and mossy fiber reorganization of the mossy fiber pathway in the dentate gyrus of the hippocampus
51. Loss of presynaptic and postsynaptic structures is accompanied by compensatory increase in action potential-dependent synaptic input to layer V neocortical pyramidal neurons in aged rats
52. Lasting potentiation of inhibition is associated with an increased number of gamma-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents
53. A receptors underlies potentiation at hippocampal inhibitory synapses
54. A receptor subunit expression and function in temporal lobe epilepsy
55. Febrile seizures in the developing brain result in persistent modification of neuronal excitability in limbic circuits
56. Dendritic but not somatic GABAergic inhibition is decreased in experimental epilepsy
57. Persistently modified H-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability
58. A receptors
59. Selective depolarization of interneurons in the early posttraumatic dentate gyrus: Involvement of the Na(+)/K(+)-ATPase