The role of protons in fast and slow gating of the Torpedo chloride channel ClC-0

European Biophysics Journal

Volumn 39, Issue 6, 2010, Pages 869-875

  Zifarelli, Giovanni ^a   Pusch, Michael ^a  

^a CNR   (Italy)

Author keywords

Anion; Antiporter; Chloride; Ion channel; Proton

Indexed keywords

CHLORIDE CHANNEL; ION; PROTON;

ANIMAL; CELL MEMBRANE POTENTIAL; CHANNEL GATING; GENETICS; METABOLISM; MUTATION; PH; PHYSIOLOGY; REVIEW; SITE DIRECTED MUTAGENESIS; TORPEDO;

ANIMALS; CHLORIDE CHANNELS; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; IONS; MEMBRANE POTENTIALS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTONS; TORPEDO;

EID: 77952090004     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-008-0393-x     Document Type: Review

References (39)

1. - channels Nature 427 803 807 10.1038/nature02314 10.1038/nature02314 1:CAS:528:DC%2BD2cXhsFCis7o%3D 14985752 (Pubitemid 38297735)
2. A Accardi M Pusch 2003 Conformational changes in the pore of CLC-0 J Gen Physiol 122 277 293 10.1085/jgp.200308834 10.1085/jgp.200308834 1:CAS:528:DC%2BD3sXnslehtrY%3D 12913090 (Pubitemid 37163277)
3. + exchanger J Gen Physiol 126 563 570 10.1085/jgp.200509417 10.1085/jgp.200509417 1:CAS:528: DC%2BD28XitFOqsg%3D%3D 16316975 (Pubitemid 41713737)
4. A Accardi S Lobet C Williams C Miller R Dutzler 2006 Synergism between halide binding and proton transport in a CLC-type exchanger J Mol Biol 362 691 699 10.1016/j.jmb.2006.07.081 10.1016/j.jmb.2006.07.081 1:CAS:528: DC%2BD28XpsVajt74%3D 16949616 (Pubitemid 44404085)
5. MF Chen TY Chen 2001 Different fast-gate regulation by external Cl(-) and H(+) of the muscle-type ClC chloride channels J Gen Physiol 118 23 32 10.1085/jgp.118.1.23 10.1085/jgp.118.1.23 1:CAS:528:DC%2BD3MXlt1yqs7s%3D 11429442 (Pubitemid 32623172)
6. - channel J Gen Physiol 108 237 250 10.1085/jgp.108.4.237 10.1085/jgp.108.4.237 1:CAS:528:DyaK28XmsFCrs7g%3D 8894974 (Pubitemid 26332536)
7. TE DeCoursey VV Cherny 1997 Deuterium isotope effects on permeation and gating of proton channels in rat alveolar epithelium J Gen Physiol 109 415 434 10.1085/jgp.109.4.415 10.1085/jgp.109.4.415 1:CAS:528:DyaK2sXisFyitL0%3D 9101402 (Pubitemid 27164461)
8. + conduction and selectivity Science 280 69 77 10.1126/science.280. 5360.69 10.1126/science.280.5360.69 1:CAS:528:DyaK1cXitlWksrY%3D 9525859 (Pubitemid 28169082)
9. R Dutzler EB Campbell M Cadene BT Chait R MacKinnon 2002 X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity Nature 415 287 294 10.1038/415287a 10.1038/415287a 1:CAS:528:DC%2BD38XptlWksA%3D%3D 11796999 (Pubitemid 34087544)
10. R Dutzler EB Campbell R MacKinnon 2003 Gating the selectivity filter in ClC chloride channels Science 300 108 112 10.1126/science.1082708 10.1126/science.1082708 1:CAS:528:DC%2BD3sXis1Cgt74%3D 12649487 (Pubitemid 36423038)
11. AM Engh JD Faraldo-Gomez M Maduke 2007 The mechanism of fast-gate opening in ClC-0 J Gen Physiol 130 335 349 10.1085/jgp.200709759 10.1085 jgp.200709759 1:CAS:528:DC%2BD2sXht1WmsrvF 17846164 (Pubitemid 47481598)
12. PK Glasoe FA Long 1960 Use of glass electrodes to measure acidities in deuterium oxide J Phys Chem 64 188 190 10.1021/j100830a521 10.1021/j100830a521 1:CAS:528:DyaF3cXmtVamug%3D%3D
13. W Hanke C Miller 1983 Single chloride channels from Torpedo electroplax. Activation by protons J Gen Physiol 82 25 45 10.1085/jgp.82.1.25 10.1085/jgp.82.1.25 1:CAS:528:DyaL3sXkvVers7Y%3D 6310023 (Pubitemid 13034085)
14. Hill TL (1977) Free energy transduction in biology. Academic Press, New York
15. + exchanger Proc Natl Acad Sci USA 105 11194 11199 10.1073/pnas.0804503105 10.1073/pnas.0804503105 1:CAS:528:DC%2BD1cXhtVShtbnK 18678918
16. TJ Jentsch 2008 CLC chloride channels and transporters: from genes to protein structure, pathology and physiology Crit Rev Biochem Mol Biol 43 3 36 10.1080/10409230701829110 10.1080/10409230701829110 1:CAS:528: DC%2BD1cXisFSqtb4%3D 18307107 (Pubitemid 351315859)
17. TJ Jentsch M Poët JC Fuhrmann AA Zdebik 2005 Physiological functions of CLC Cl channels gleaned from human genetic disease and mouse models Annu Rev Physiol 67 779 807 10.1146/annurev.physiol.67.032003.153245 10.1146/annurev.physiol.67.032003.153245 1:CAS:528:DC%2BD2MXjsFeks7Y%3D 15709978 (Pubitemid 40404510)
18. J Kasianowicz R Benz S McLaughlin 1987 How do protons cross the membrane-solution interface? Kinetic studies on bilayer membranes exposed to the protonophore S-13 (5-chloro-3-tert-butyl-2-chloro-4 nitrosalicylanilide) J Membr Biol 95 73 89 10.1007/BF01869632 10.1007/BF01869632 1:CAS:528: DyaL2sXkslaqtrY%3D 3031309 (Pubitemid 17010645)
19. + antiporter Nat Struct Mol Biol 15 805 810 10.1038/nsmb.1466 10.1038/nsmb.1466 18641661
20. U Ludewig M Pusch TJ Jentsch 1996 Two physically distinct pores in the dimeric ClC-0 chloride channel Nature 383 340 343 10.1038/383340a0 10.1038/383340a0 1:CAS:528:DyaK28XlvFaitr8%3D 8848047 (Pubitemid 26321764)
21. U Ludewig TJ Jentsch M Pusch 1997 Analysis of a protein region involved in permeation and gating of the voltage-gated Torpedo chloride channel ClC-0 J Physiol 498 691 702 1:CAS:528:DyaK2sXhsFeiurw%3D 9051580 (Pubitemid 27089464)
22. RE Middleton DJ Pheasant C Miller 1996 Homodimeric architecture of a ClC-type chloride ion channel Nature 383 337 340 10.1038/383337a0 10.1038/383337a0 1:CAS:528:DyaK28XlvFaitr4%3D 8848046 (Pubitemid 26321763)
23. C Miller 1982 Open-state substructure of single chloride channels from Torpedo electroplax Philos Trans R Soc Lond B Biol Sci 299 401 411 10.1098/rstb.1982.0140 10.1098/rstb.1982.0140 1:CAS:528:DyaL3sXivFynsA%3D%3D 6130538
24. C Miller 2006 ClC chloride channels viewed through a transporter lens Nature 440 484 489 10.1038/nature04713 10.1038/nature04713 1:CAS:528: DC%2BD28Xis1OlsLY%3D 16554809
25. Mindell JA, Maduke M (2001) ClC chloride channels. Genome Biol 2. Review S3003
26. A Picollo M Pusch 2005 Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5 Nature 436 420 423 10.1038/nature03720 10.1038/nature03720 1:CAS:528:DC%2BD2MXmtlSjtLg%3D 16034421 (Pubitemid 41059054)
27. M Pusch 2004 Structural insights into chloride and proton-mediated gating of CLC chloride channels Biochemistry 43 1135 1144 10.1021/bi0359776 10.1021/bi0359776 1:CAS:528:DC%2BD2cXosFGksA%3D%3D 14756549 (Pubitemid 38176511)
28. M Pusch U Ludewig A Rehfeldt TJ Jentsch 1995 Gating of the voltage- ependent chloride channel CIC-0 by the permeant anion Nature 373 527 531 10.1038/373527a0 10.1038/373527a0 1:CAS:528:DyaK2MXjs1Wns70%3D 7845466
29. M Pusch SE Jordt V Stein TJ Jentsch 1999 Chloride dependence of hyperpolarization-activated chloride channel gates J Physiol 515 341 353 10.1111/j.1469-7793.1999.341ac.x 10.1111/j.1469-7793.1999.341ac.x 1:CAS:528:DyaK1MXisFyqu7o%3D 10050002
30. EA Richard C Miller 1990 Steady-state coupling of ion-channel conformations to a transmembrane ion gradient Science 247 1208 1210 10.1126/science.2156338 10.1126/science.2156338 1:STN:280:DyaK3c7ptlKkug%3D%3D 2156338 (Pubitemid 20102479)
31. O Scheel AA Zdebik S Lourdel TJ Jentsch 2005 Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins Nature 436 424 427 10.1038/nature03860 10.1038/nature03860 1:CAS:528:DC%2BD2MXmtlSjtbc%3D 16034422 (Pubitemid 41059055)
32. C Toyoshima M Nakasako H Nomura H Ogawa 2000 Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6-Å resolution Nature 405 647 655 10.1038/35015017 10.1038/35015017 1:CAS:528:DC%2BD3cXktlCis74%3D 10864315 (Pubitemid 30428644)
33. S Traverso L Elia M Pusch 2003 Gating competence of constitutively open CLC-0 mutants revealed by the interaction with a small organic Inhibitor J Gen Physiol 122 295 306 10.1085/jgp.200308784 10.1085/jgp.200308784 1:CAS:528:DC%2BD3sXnslehtrc%3D 12913089 (Pubitemid 37163278)
34. S Traverso G Zifarelli R Aiello M Pusch 2006 Proton sensing of CLC-0 mutant E166D J Gen Physiol 127 51 66 10.1085/jgp.200509340 10.1085/jgp.200509340 1:CAS:528:DC%2BD28XovVymtA%3D%3D 16380443 (Pubitemid 43036446)
35. + exchange transporter J Gen Physiol 129 317 329 10.1085/jgp.200709756 10.1085/jgp.200709756 1:CAS:528: DC%2BD2sXkvVaisrw%3D 17389248 (Pubitemid 46506982)
36. F Weinreich TJ Jentsch 2001 Pores formed by single subunits in mixed dimers of different CLC chloride channels J Biol Chem 276 2347 2353 10.1074/jbc.M005733200 10.1074/jbc.M005733200 1:CAS:528:DC%2BD3MXhtVCqu7Y%3D 11035003 (Pubitemid 37376601)
37. AA Zdebik G Zifarelli EY Bergsdorf P Soliani O Scheel TJ Jentsch M Pusch 2008 Determinants of anion-proton coupling in mammalian endosomal CLC proteins J Biol Chem 283 4219 4227 10.1074/jbc.M708368200 10.1074/jbc.M708368200 1:CAS:528:DC%2BD1cXhs1Wgtbw%3D 18063579
38. G Zifarelli M Pusch 2007 CLC chloride channels and transporters: a biophysical and physiological perspective Rev Physiol Biochem Pharmacol 158 23 76 10.1007/112-2006-0605 10.1007/112-2006-0605 1:CAS:528:DC%2BD2sXot1Sms7Y%3D 17729441
39. G Zifarelli AR Murgia P Soliani M Pusch 2008 Intracellular proton regulation of ClC-0 J Gen Physiol 132 185 198 10.1085/jgp.200809999 10.1085/jgp.200809999 1:CAS:528:DC%2BD1cXptFyrsLY%3D 18591423