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Volumn 109, Issue 4, 1997, Pages 415-434

Deuterium isotope effects on permeation and gating of proton channels in rat alveolar epithelium

Author keywords

ion channels; membrane transport; pH; pneumocytes; proton transport

Indexed keywords

DEUTERIUM; PROTON;

EID: 0030950444     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.109.4.415     Document Type: Article
Times cited : (103)

References (83)
  • 1
    • 11744384413 scopus 로고
    • The Grotthuss mechanism
    • Agmon, N. 1995. The Grotthuss mechanism. Chem. Phys. Lett. 244: 456-462.
    • (1995) Chem. Phys. Lett. , vol.244 , pp. 456-462
    • Agmon, N.1
  • 2
    • 2242418317 scopus 로고    scopus 로고
    • Hydrogen bonds, water rotation and proton mobility
    • Agmon, N. 1996. Hydrogen bonds, water rotation and proton mobility. J. Chim. Phys. (Paris). 93:1714-1736.
    • (1996) J. Chim. Phys. (Paris) , vol.93 , pp. 1714-1736
    • Agmon, N.1
  • 4
    • 0025343664 scopus 로고
    • Sodium channel activation mechanisms: Insights from deuterium oxide substitution
    • Alicata, D.A., M.D. Rayner, and J.G. Starkus. 1990. Sodium channel activation mechanisms: insights from deuterium oxide substitution. Biophys. J. 57:745-758.
    • (1990) Biophys. J. , vol.57 , pp. 745-758
    • Alicata, D.A.1    Rayner, M.D.2    Starkus, J.G.3
  • 5
    • 0024400370 scopus 로고
    • 0: Its time-averaged single-channel conductance as a function of pH, temperature, isotopic and ionic medium composition
    • 0: its time-averaged single-channel conductance as a function of pH, temperature, isotopic and ionic medium composition. J. Membr. Biol. 108:263-271.
    • (1989) J. Membr. Biol. , vol.108 , pp. 263-271
    • Althoff, G.1    Lill, H.2    Junge, W.3
  • 6
    • 0020630896 scopus 로고
    • Ion movement through gramicidin A channels: Studies on the diffusion-controlled association step
    • Andersen, O.S. 1983. Ion movement through gramicidin A channels: studies on the diffusion-controlled association step. Biophys. J. 41:147-165.
    • (1983) Biophys. J. , vol.41 , pp. 147-165
    • Andersen, O.S.1
  • 7
    • 0021287082 scopus 로고
    • A voltage-gated hydrogen ion current in the oocyte membrane of the axolotl, Ambystoma
    • Barish, M.E., and C. Baud. 1984. A voltage-gated hydrogen ion current in the oocyte membrane of the axolotl, Ambystoma. J. Physiol. (Lond.). 352:243-263.
    • (1984) J. Physiol. (Lond.) , vol.352 , pp. 243-263
    • Barish, M.E.1    Baud, C.2
  • 9
    • 0346735076 scopus 로고
    • A theory of water and ionic solution, with particular reference to hydrogen and hydroxyl ions
    • Bernal, J.D., and R.H. Fowler. 1933. A theory of water and ionic solution, with particular reference to hydrogen and hydroxyl ions. J. Chem. Phys. 1:515-548.
    • (1933) J. Chem. Phys. , vol.1 , pp. 515-548
    • Bernal, J.D.1    Fowler, R.H.2
  • 10
    • 0004304197 scopus 로고
    • Osmotic effects of deuterium oxide (heavy water) on living cells
    • Brooks, S.C. 1937. Osmotic effects of deuterium oxide (heavy water) on living cells. Science (Wash. DC). 86:497-498.
    • (1937) Science (Wash. DC) , vol.86 , pp. 497-498
    • Brooks, S.C.1
  • 11
    • 0021287459 scopus 로고
    • Rapidly activating hydrogen ion currents in perfused neurones of the snail, Lymnaea stagnalis
    • Byerly, L., R. Meech, and W. Moody. 1984. Rapidly activating hydrogen ion currents in perfused neurones of the snail, Lymnaea stagnalis. J. Physiol. (Lond.). 351:199-216.
    • (1984) J. Physiol. (Lond.) , vol.351 , pp. 199-216
    • Byerly, L.1    Meech, R.2    Moody, W.3
  • 12
    • 0001751278 scopus 로고
    • Theoretical models for interpreting the dielectric behavior of HF-doped ice
    • Camplin, G.C., J.W. Glen, andJ.G. Paren. 1978. Theoretical models for interpreting the dielectric behavior of HF-doped ice. J. Glaciology. 85:123-141.
    • (1978) J. Glaciology , vol.85 , pp. 123-141
    • Camplin, G.C.1    Glen, J.W.2    Paren, J.G.3
  • 13
    • 0028949144 scopus 로고
    • Relationship of proton release at the extracellular surface to deprotonation of the Schiff base in the bacteriorhodopsin photocycle
    • Cao, Y., L.S. Brown, J. Sasaki, A. Maeda, R. Needleman, and J.K. Lanyi. 1995. Relationship of proton release at the extracellular surface to deprotonation of the Schiff base in the bacteriorhodopsin photocycle. Biophys. J. 68:1518-1530.
    • (1995) Biophys. J. , vol.68 , pp. 1518-1530
    • Cao, Y.1    Brown, L.S.2    Sasaki, J.3    Maeda, A.4    Needleman, R.5    Lanyi, J.K.6
  • 14
    • 0029758770 scopus 로고    scopus 로고
    • Transalveolar osmotic and diffusional water permeability in intact mouse lung measured by a novel surface fluorescence method
    • Carter, E.P., M.A. Matthay. J. Farinas, and A.S. Verkman. 1996. Transalveolar osmotic and diffusional water permeability in intact mouse lung measured by a novel surface fluorescence method. J. Gen. Physiol. 108:133-142.
    • (1996) J. Gen. Physiol. , vol.108 , pp. 133-142
    • Carter, E.P.1    Matthay, M.A.2    Farinas, J.3    Verkman, A.S.4
  • 16
    • 0029034117 scopus 로고
    • The voltage-activated hydrogen ion conductance in rat alveolar epithelial cells is determined by the pH gradient
    • Cherny, V.V., V.S. Markin, and T.E. DeCoursey. 1995. The voltage-activated hydrogen ion conductance in rat alveolar epithelial cells is determined by the pH gradient. J. Gen. Physiol. 105:861-896.
    • (1995) J. Gen. Physiol. , vol.105 , pp. 861-896
    • Cherny, V.V.1    Markin, V.S.2    DeCoursey, T.E.3
  • 17
    • 0029816765 scopus 로고    scopus 로고
    • Selective permeability and pH regulation of the influenza virus M2 channel expressed in mouse erythroleukemia cells
    • Chizhmakov, I.V., F.M. Geraghty, D.C. Ogden, A. Hayhurst, M. Antoniou, and A.J. Hay. 1996. Selective permeability and pH regulation of the influenza virus M2 channel expressed in mouse erythroleukemia cells. J. Physiol. (Lond.). 494:329-336.
    • (1996) J. Physiol. (Lond.) , vol.494 , pp. 329-336
    • Chizhmakov, I.V.1    Geraghty, F.M.2    Ogden, D.C.3    Hayhurst, A.4    Antoniou, M.5    Hay, A.J.6
  • 20
    • 15644378394 scopus 로고
    • Rapid exchange between deutero-ammonia and hydrazine
    • Cross, P.C., and P.A. Leighton. 1938. Rapid exchange between deutero-ammonia and hydrazine. J. Am. Chem. Soc. 60:981-982.
    • (1938) J. Am. Chem. Soc. , vol.60 , pp. 981-982
    • Cross, P.C.1    Leighton, P.A.2
  • 22
    • 0023429474 scopus 로고
    • Proton permeation of lipid bilayers
    • Deamer, D.W. 1987. Proton permeation of lipid bilayers. J. Bioenerg. Biomembr. 19:457-479.
    • (1987) J. Bioenerg. Biomembr. , vol.19 , pp. 457-479
    • Deamer, D.W.1
  • 23
    • 77957585056 scopus 로고
    • Mechanisms of proton-hydroxide flux across membranes
    • A. Pullman, V. Vasilescu, and L. Packer, editors. Plenum Press, New York
    • Deamer, D.W., and J.W. Nichols. 1985. Mechanisms of proton-hydroxide flux across membranes. In Water and Ions in Biological Systems. A. Pullman, V. Vasilescu, and L. Packer, editors. Plenum Press, New York. 469-481.
    • (1985) Water and Ions in Biological Systems , pp. 469-481
    • Deamer, D.W.1    Nichols, J.W.2
  • 25
    • 0025307982 scopus 로고
    • + currents in rat type II alveolar epithelial cells
    • + currents in rat type II alveolar epithelial cells. J. Gen. Physiol. 95:617-646.
    • (1990) J. Gen. Physiol. , vol.95 , pp. 617-646
    • DeCoursey, T.E.1
  • 26
    • 0025723509 scopus 로고
    • Hydrogen ion currents in rat alveolar epithelial cells
    • DeCoursey, T.E. 1991. Hydrogen ion currents in rat alveolar epithelial cells. Biophys. J. 60:1243-1253.
    • (1991) Biophys. J. , vol.60 , pp. 1243-1253
    • DeCoursey, T.E.1
  • 27
    • 0028805759 scopus 로고
    • + channel block by verapamil and related compounds in rat alveolar epithelial cells
    • + channel block by verapamil and related compounds in rat alveolar epithelial cells. J. Gen. Physiol. 106:745-779.
    • (1995) J. Gen. Physiol. , vol.106 , pp. 745-779
    • DeCoursey, T.E.1
  • 28
    • 0028129189 scopus 로고
    • Voltage-activated hydrogen ion currents
    • DeCoursey, T.E., and V.V. Cherny. 1994. Voltage-activated hydrogen ion currents. J. Membr. Biol. 141:203-223.
    • (1994) J. Membr. Biol. , vol.141 , pp. 203-223
    • DeCoursey, T.E.1    Cherny, V.V.2
  • 29
    • 0029597849 scopus 로고
    • Voltage-activated proton currents in membrane patches of rat alveolar epithelial cells
    • DeCoursey, T.E., and V.V. Cherny. 1995. Voltage-activated proton currents in membrane patches of rat alveolar epithelial cells. J. Physiol. (Lond.). 489:299-307.
    • (1995) J. Physiol. (Lond.) , vol.489 , pp. 299-307
    • DeCoursey, T.E.1    Cherny, V.V.2
  • 30
    • 0029657719 scopus 로고    scopus 로고
    • II. Voltage-activated proton currents in human THP-1 monocytes
    • DeCoursey, T.E., and V.V. Cherny. 1996a. II. Voltage-activated proton currents in human THP-1 monocytes. J. Membr. Biol. 152: 131-140.
    • (1996) J. Membr. Biol. , vol.152 , pp. 131-140
    • DeCoursey, T.E.1    Cherny, V.V.2
  • 31
    • 0029973362 scopus 로고    scopus 로고
    • + currents: Does diffusion limit the conductance?
    • + currents: does diffusion limit the conductance? Biophys. J. 71:182-193.
    • (1996) Biophys. J. , vol.71 , pp. 182-193
    • DeCoursey, T.E.1    Cherny, V.V.2
  • 32
    • 15644366370 scopus 로고    scopus 로고
    • Where is the rate-limiting step in permeation through voltage-gated proton channels?
    • Abstr.
    • DeCoursey, T.E., and V.V. Cherny. 1997. Where is the rate-limiting step in permeation through voltage-gated proton channels? Biophys. J. 72:A108. (Abstr.).
    • (1997) Biophys. J. , vol.72
    • DeCoursey, T.E.1    Cherny, V.V.2
  • 33
    • 0023852692 scopus 로고
    • Potassium currents in rat type II alveolar epithelial cells
    • DeCoursey, T.E., E.R. Jacobs, and M.R. Silver. 1988. Potassium currents in rat type II alveolar epithelial cells. J. Physiol. (Lond.). 395: 487-505.
    • (1988) J. Physiol. (Lond.) , vol.395 , pp. 487-505
    • DeCoursey, T.E.1    Jacobs, E.R.2    Silver, M.R.3
  • 34
    • 0000934825 scopus 로고
    • Self-dissociation and protonic charge transport in water and ice
    • Eigen, M., and L. DeMaeyer. 1958. Self-dissociation and protonic charge transport in water and ice. Proc. R. Soc. Lond., A. 247:505-533.
    • (1958) Proc. R. Soc. Lond., A , vol.247 , pp. 505-533
    • Eigen, M.1    DeMaeyer, L.2
  • 37
    • 0001303844 scopus 로고
    • Water movement through membrane channels
    • Finkelstein, A. 1984. Water movement through membrane channels. Curr. Topics Membr. Transp. 21:295-308.
    • (1984) Curr. Topics Membr. Transp. , vol.21 , pp. 295-308
    • Finkelstein, A.1
  • 38
    • 0019795013 scopus 로고
    • The gramicidin A channel: A review of its permeability characteristics with special reference to the single-file aspect of transport
    • Finkelstein, A., and O.S. Andersen. 1981. The gramicidin A channel: a review of its permeability characteristics with special reference to the single-file aspect of transport. J. Membr. Biol. 59:155-171.
    • (1981) J. Membr. Biol. , vol.59 , pp. 155-171
    • Finkelstein, A.1    Andersen, O.S.2
  • 39
  • 40
    • 6444222991 scopus 로고
    • Use of glass electrodes to measure acidities in deuterium oxide
    • Glasoe, P.K., and F.A. Long. 1960. Use of glass electrodes to measure acidities in deuterium oxide. J. Phys. Chem. 64:188-190.
    • (1960) J. Phys. Chem. , vol.64 , pp. 188-190
    • Glasoe, P.K.1    Long, F.A.2
  • 42
    • 85012319658 scopus 로고
    • Potential, impedance, and rectification in membranes
    • Goldman, D.E. 1943. Potential, impedance, and rectification in membranes. J. Gen. Physiol. 27:37-60.
    • (1943) J. Gen. Physiol. , vol.27 , pp. 37-60
    • Goldman, D.E.1
  • 44
    • 0014520535 scopus 로고
    • 2O at 35 GHz over the temperature range 4-62.5°C
    • 2O at 35 GHz over the temperature range 4-62.5°C. Trans. Faraday Soc. 65: 1519-1522.
    • (1969) Trans. Faraday Soc. , vol.65 , pp. 1519-1522
    • Grant, E.H.1    Shack, R.2
  • 45
    • 0028002838 scopus 로고
    • Method for manipulation of cytosolic pH in cells clamped in the whole cell or perforated-patch configurations
    • Grinstein, S., R. Romanek, and O.D. Rotstein. 1994. Method for manipulation of cytosolic pH in cells clamped in the whole cell or perforated-patch configurations. Am. J. Physiol. 267:C1152-C1159.
    • (1994) Am. J. Physiol. , vol.267
    • Grinstein, S.1    Romanek, R.2    Rotstein, O.D.3
  • 46
    • 0023428319 scopus 로고
    • Proton conductance through phospholipid bilayers: Water wires or weak acids?
    • Gutknecht, J. 1987. Proton conductance through phospholipid bilayers: water wires or weak acids? J. Bioenerg. Biomembr. 19:427-442.
    • (1987) J. Bioenerg. Biomembr. , vol.19 , pp. 427-442
    • Gutknecht, J.1
  • 47
    • 0000763944 scopus 로고
    • Viscosity of deuterium oxide and water in the range of 5° to 125°C
    • Hardy, R.C., and R.L. Cottington. 1949. Viscosity of deuterium oxide and water in the range of 5° to 125°C. J. Res. Natl. Bureau of Standards. 42:573-578.
    • (1949) J. Res. Natl. Bureau of Standards , vol.42 , pp. 573-578
    • Hardy, R.C.1    Cottington, R.L.2
  • 48
    • 0027989801 scopus 로고
    • Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues
    • Hasegawa, H., T. Ma, W. Skach, M.A. Matthay, and A.S. Verkman. 1994. Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. J. Biol. Chem. 269:5497-5500.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5497-5500
    • Hasegawa, H.1    Ma, T.2    Skach, W.3    Matthay, M.A.4    Verkman, A.S.5
  • 50
    • 78651026696 scopus 로고
    • The effects of sodium ions on the electrical activity of the giant axon of the squid
    • Hodgkin, A.L., and B. Katz. 1949. The effects of sodium ions on the electrical activity of the giant axon of the squid. J. Physiol. (Lond.). 108:37-77.
    • (1949) J. Physiol. (Lond.) , vol.108 , pp. 37-77
    • Hodgkin, A.L.1    Katz, B.2
  • 51
    • 0000973004 scopus 로고
    • Theorie der beweglichkeiten des Wasserstoff- und hydroxylions in wässriger lösung
    • Hückel, E. 1928. Theorie der beweglichkeiten des Wasserstoff- und hydroxylions in wässriger lösung. Zeitschrift Elektrochemie Angewandte Physikalische Chemie. 34:546-562.
    • (1928) Zeitschrift Elektrochemie Angewandte Physikalische Chemie. , vol.34 , pp. 546-562
    • Hückel, E.1
  • 53
    • 0024948544 scopus 로고
    • Protons, the thylakoid membrane, and the chloroplast ATP synthase
    • Junge, W. 1989. Protons, the thylakoid membrane, and the chloroplast ATP synthase. Ann. N Y Acad. Sci. 574:268-285.
    • (1989) Ann. N Y Acad. Sci. , vol.574 , pp. 268-285
    • Junge, W.1
  • 54
    • 0027518218 scopus 로고
    • A pH-sensitive and voltage-dependent proton conductance in the plasma membrane of macrophages
    • Kapus, A., R. Romanek, A.Y. Qu, O.D. Rotstein, and S. Grinstein. 1993. A pH-sensitive and voltage-dependent proton conductance in the plasma membrane of macrophages. J. Gen. Physiol. 102: 729-760.
    • (1993) J. Gen. Physiol. , vol.102 , pp. 729-760
    • Kapus, A.1    Romanek, R.2    Qu, A.Y.3    Rotstein, O.D.4    Grinstein, S.5
  • 55
    • 0028980231 scopus 로고
    • Protonation dynamics of the α-toxin ion channel from spectral analysis of pH-dependent current fluctuations
    • Kasianowicz, J.J., and S.M. Bezrukov. 1995. Protonation dynamics of the α-toxin ion channel from spectral analysis of pH-dependent current fluctuations. Biophys. J. 69:94-105.
    • (1995) Biophys. J. , vol.69 , pp. 94-105
    • Kasianowicz, J.J.1    Bezrukov, S.M.2
  • 56
    • 0002621229 scopus 로고
    • Secondary kinetic isotope effects
    • W.W. Cleland, M.H. O'Leary, and D.B. Northrop, editors. University Park Press, Baltimore
    • Kirsch, J.F. 1977. Secondary kinetic isotope effects. In Isotope Effects on Enzyme-Catalyzed Reactions. W.W. Cleland, M.H. O'Leary, and D.B. Northrop, editors. University Park Press, Baltimore. 100-121.
    • (1977) Isotope Effects on Enzyme-Catalyzed Reactions , pp. 100-121
    • Kirsch, J.F.1
  • 58
    • 0019102490 scopus 로고
    • Proton mobility in ice
    • Kunst, M., and J.M. Warman. 1980. Proton mobility in ice. Nature (Lond.). 288:465-467.
    • (1980) Nature (Lond.) , vol.288 , pp. 465-467
    • Kunst, M.1    Warman, J.M.2
  • 60
    • 0018072320 scopus 로고
    • Number of water molecules coupled to the transport of sodium, potassium and hydrogen ions via gramicidin, nonactin or valinomycin
    • Levitt, D.G., S.R. Elias, and J.M. Hautman. 1978. Number of water molecules coupled to the transport of sodium, potassium and hydrogen ions via gramicidin, nonactin or valinomycin. Biochim. Biophys. Acta. 512:436-451.
    • (1978) Biochim. Biophys. Acta , vol.512 , pp. 436-451
    • Levitt, D.G.1    Elias, S.R.2    Hautman, J.M.3
  • 61
    • 0021917383 scopus 로고
    • Deuterium oxide and temperature effects on the properties of endplate channels at the frog neuromuscular junction
    • Lewis, C.A. 1985. Deuterium oxide and temperature effects on the properties of endplate channels at the frog neuromuscular junction. J. Physiol. (Lond.). 85:137-156.
    • (1985) J. Physiol. (Lond.) , vol.85 , pp. 137-156
    • Lewis, C.A.1
  • 63
    • 15644380371 scopus 로고
    • The ionization of some weak electrolytes in heavy water
    • Lewis, G.N., and P.W. Schutz. 1934. The ionization of some weak electrolytes in heavy water. J. Am. Chem. Soc. 56:1913-1915.
    • (1934) J. Am. Chem. Soc. , vol.56 , pp. 1913-1915
    • Lewis, G.N.1    Schutz, P.W.2
  • 64
    • 0016316309 scopus 로고
    • The effect of holding potential on the asymmetry currents in squid giant axons
    • Meves, H. 1974. The effect of holding potential on the asymmetry currents in squid giant axons. J. Physiol. (Lond.). 243:847-867.
    • (1974) J. Physiol. (Lond.) , vol.243 , pp. 847-867
    • Meves, H.1
  • 65
    • 0015499163 scopus 로고
    • Ion transfer across lipid membranes in the presence of gramicidin A: The ion selectivity
    • Myers, V.B., and D.A. Haydon. 1972. Ion transfer across lipid membranes in the presence of gramicidin A: the ion selectivity. Biochim. Biophys. Acta. 274:313-322.
    • (1972) Biochim. Biophys. Acta , vol.274 , pp. 313-322
    • Myers, V.B.1    Haydon, D.A.2
  • 66
    • 0023428452 scopus 로고
    • Theory of passive proton conductance in lipid bilayers
    • Nagle, J.F. 1987. Theory of passive proton conductance in lipid bilayers. J. Bioenerg. Biomembr. 19:413-426.
    • (1987) J. Bioenerg. Biomembr. , vol.19 , pp. 413-426
    • Nagle, J.F.1
  • 67
    • 0345613372 scopus 로고
    • Molecular mechanisms for proton transport in membranes
    • Nagle, J.F., and H.J. Morowitz. 1978. Molecular mechanisms for proton transport in membranes. Prac. Natl. Acad. Sci. USA. 75: 298-302.
    • (1978) Prac. Natl. Acad. Sci. USA , vol.75 , pp. 298-302
    • Nagle, J.F.1    Morowitz, H.J.2
  • 68
    • 0020967882 scopus 로고
    • Hydrogen bonded chain mechanisms for proton conduction and proton pumping
    • Nagle, J.F., and S. Tristram-Nagle. 1983. Hydrogen bonded chain mechanisms for proton conduction and proton pumping. J. Membr. Biol. 74:1-14.
    • (1983) J. Membr. Biol. , vol.74 , pp. 1-14
    • Nagle, J.F.1    Tristram-Nagle, S.2
  • 70
    • 0030011088 scopus 로고    scopus 로고
    • + translocation along the single-file water chain in the gramicidin A channel
    • + translocation along the single-file water chain in the gramicidin A channel. Biophys. J. 71:19-39.
    • (1996) Biophys. J. , vol.71 , pp. 19-39
    • Pomes̀, R.1    Roux, B.2
  • 72
    • 0012722381 scopus 로고
    • Proton and deuteron mobility in normal and heavy water solutions of electrolytes
    • Roberts, N.K., and H.L. Northey. 1974. Proton and deuteron mobility in normal and heavy water solutions of electrolytes. J. Chem. Soc., Faraday Transactions I. 70:253-262.
    • (1974) J. Chem. Soc., Faraday Transactions I , vol.70 , pp. 253-262
    • Roberts, N.K.1    Northey, H.L.2
  • 74
    • 0019554835 scopus 로고
    • Intracellular pH
    • Roos, A., and W.F. Boron. 1981. Intracellular pH. Physiol. Rev. 61: 296-434.
    • (1981) Physiol. Rev. , vol.61 , pp. 296-434
    • Roos, A.1    Boron, W.F.2
  • 75
    • 0028077663 scopus 로고
    • Two identical noninteracting sites in an ion channel revealed by proton transfer
    • Root, M.J., and R. MacKinnon. 1994. Two identical noninteracting sites in an ion channel revealed by proton transfer. Science (Wash. DC). 265:1852-1856.
    • (1994) Science (Wash. DC) , vol.265 , pp. 1852-1856
    • Root, M.J.1    MacKinnon, R.2
  • 76
    • 0018895840 scopus 로고
    • 2O on some components of membrane conductance
    • 2O on some components of membrane conductance. Biophys. J. 30:295-305.
    • (1980) Biophys. J. , vol.30 , pp. 295-305
    • Schauf, C.L.1    Bullock, J.O.2
  • 77
    • 0020025443 scopus 로고
    • 2O on kinetic properties of drugs that occlude channels
    • 2O on kinetic properties of drugs that occlude channels. Biophys. J. 37:441-452.
    • (1982) Biophys. J. , vol.37 , pp. 441-452
    • Schauf, C.L.1    Bullock, J.O.2
  • 78
    • 0002018792 scopus 로고
    • Solvent isotope effects on enzymic reactions
    • W.W. Cleland, M.H. O'Leary, and D.B. Northrop, editors. University Park Press, Baltimore
    • Schowen, R.L. 1977. Solvent isotope effects on enzymic reactions. In Isotope Effects on Enzyme-Catalyzed Reactions. W.W. Cleland, M.H. O'Leary, and D.B. Northrop, editors. University Park Press, Baltimore. 64-99.
    • (1977) Isotope Effects on Enzyme-Catalyzed Reactions , pp. 64-99
    • Schowen, R.L.1
  • 79
    • 0029805540 scopus 로고    scopus 로고
    • Novel chloride-dependent acid loader in the guinea-pig ventricular myocyte: Part of a dual acid-loading system
    • Sun, B., C.H. Leem, and R.D. Vaughan-Jones. 1996. Novel chloride-dependent acid loader in the guinea-pig ventricular myocyte: part of a dual acid-loading system. J. Physiol. 495:65-82.
    • (1996) J. Physiol. , vol.495 , pp. 65-82
    • Sun, B.1    Leem, C.H.2    Vaughan-Jones, R.D.3
  • 80
    • 0023852798 scopus 로고
    • + fluxes through a channel
    • + fluxes through a channel. J. Physiol. (Lond.). 398:313-327.
    • (1988) J. Physiol. (Lond.) , vol.398 , pp. 313-327
    • Thomas, R.C.1
  • 81
    • 0024340992 scopus 로고
    • Mechanisms of water transport by epithelial cells
    • Tripathi, S., and E.L. Boulpaep. 1989. Mechanisms of water transport by epithelial cells. Q. J. Exp. Physiol. 74:385-417.
    • (1989) Q. J. Exp. Physiol. , vol.74 , pp. 385-417
    • Tripathi, S.1    Boulpaep, E.L.2
  • 82
    • 0018393094 scopus 로고
    • A study of gramicidin using deuterium oxide
    • Tredgold, R.H., and R. Jones. 1979. A study of gramicidin using deuterium oxide. Biochim. Biophys. Acta. 550:543-545.
    • (1979) Biochim. Biophys. Acta , vol.550 , pp. 543-545
    • Tredgold, R.H.1    Jones, R.2


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