Proton sensing of CLC-0 mutant E166D

Journal of General Physiology

Volumn 127, Issue 1, 2006, Pages 51-65

  Traverso, Sonia ^a   Zifarelli, Giovanni ^a   Aiello, Rita ^a   Pusch, Michael ^a  

^a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONDUCTANCE; DIMERIZATION; EXTRACELLULAR MATRIX; GENE MUTATION; MEMBRANE CURRENT; PH MEASUREMENT; PHENOTYPE; PROTON TRANSPORT; TANDEM MASS SPECTROMETRY; WILD TYPE;

ANIMALS; ASPARTIC ACID; CHLORIDE CHANNELS; ELECTRIC CONDUCTIVITY; FEMALE; GLUTAMIC ACID; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MATHEMATICS; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTONS; TORPEDO; VOLTAGE-DEPENDENT ANION CHANNELS; XENOPUS LAEVIS;

EID: 29844437654     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200509340     Document Type: Article

References (37)

1. - channels. Nature. 427:803-807.
2. Accardi, A., and M. Pusch. 2000. Fast and slow gating relaxations in the muscle chloride channel CLC-1. J. Gen. Physiol. 116:433-444.
3. Accardi, A., and M. Pusch. 2003. Conformational changes in the pore of CLC-0. J. Gen. Physiol. 122:277-293.
4. Accardi, A., L. Ferrera, and M. Pusch. 2001. Drastic reduction of the slow gate of human muscle chloride channel (ClC-1) by mutation C277S. J. Physiol. 534:745-752.
5. Bauer, C.K., K. Steinmeyer, J.R. Schwarz, and T.J. Jentsch. 1991. Completely functional double-barreled chloride channel expressed from a single Torpedo cDNA. Proc. Natl. Acad. Sci. USA. 88:11052-11056.
6. Bisset, D., B. Corry, and S.H. Chung. 2005. The fast gating mechanism in ClC-0 channels. Biophys. J. 89:179-186.
7. + of the muscle-type ClC chloride channels. J. Gen. Physiol. 118:23-32.
8. - channel. J. Gen. Physiol. 108:237-250.
9. Colquhoun, D., and A.G. Hawkes. 1990. Stochastic properties of ion channel openings and bursts in a membrane patch that contains two channels: evidence concerning the number of channels present when a record containing only single openings is observed. Proc. R. Soc. Lond. B. Biol. Sci. 240:453-477.
10. Dutzler, R., E.B. Campbell, M. Cadene, B.T. Chait, and R. MacKinnon. 2002. X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity. Nature. 415:287-294.
11. Dutzler, R., E.B. Campbell, and R. MacKinnon. 2003. Gating the selectivity filter in ClC chloride channels. Science. 300:108-112.
12. Estévez, R., B.C. Schroeder, A. Accardi, T.J. Jentsch, and M. Pusch. 2003. Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1. Neuron. 38:47-59.
13. Fersht, A. 1998. Structure and Mechanism in Protein Science. WH Freeman and Company, New York. 631 pp.
14. Hanke, W., and C. Miller. 1983. Single chloride channels from Torpedo electroplax. Activation by protons. J. Gen. Physiol. 82:25-45.
15. Heinemann, S.H., and F. Conti. 1992. Nonstationary noise analysis and application to patch clamp recordings. Methods Enzymol. 207:131-148.
16. Jentsch, T.J., K. Steinmeyer, and G. Schwarz. 1990. Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes. Nature. 348:510-514.
17. Jentsch, T.J., M. Poet, J.C. Fuhrmann, and A.A. Zdebik. 2005. Physiological functions of CLC Cl channels gleaned from human genetic disease and mouse models. Annu. Rev. Physiol. 67:779-807.
18. Lin, C.W., and T.Y. Chen. 2003. Probing the pore of ClC-0 by substituted cysteine accessibility method using methane thiosulfonate reagents. J. Gen. Physiol. 122:147-159.
19. Lin, Y.W., C.W. Lin, and T.Y. Chen. 1999. Elimination of the slow gating of ClC-0 chloride channel by a point mutation. J. Gen. Physiol. 114:1-12.
20. Lorenz, C., M. Pusch, and T.J. Jentsch. 1996. Heteromultimeric CLC chloride channels with novel properties. Proc. Natl. Acad. Sci. USA. 93:13362-13366.
21. Ludewig, U., M. Pusch, and T.J. Jentsch. 1996. Two physically distinct pores in the dimeric ClC-0 chloride channel. Nature. 383:340-343.
22. Ludewig, U., T.J. Jentsch, and M. Pusch. 1997. Inward rectification in ClC-0 chloride channels caused by mutations in several protein regions. J. Gen. Physiol. 110:165-171.
23. Middleton, R.E., D.J. Pheasant, and C. Miller. 1996. Homodimeric architecture of a ClC-type chloride ion channel. Nature. 383:337-340.
24. Miller, C., and E.A. Richard. 1990. The voltage-dependent chloride channel of Torpedo electroplax. Intimations of molecular structure from quirks of single-channel function. In Chloride Channels and Carriers in Nerve, Muscle and Glial Cells. F.J. Alvarez-Leefmans and J.M. Russell, editors. Plenum, New York. 383-405.
25. Miller, C., and M.M. White. 1980. A voltage-dependent chloride conductance channel from Torpedo electroplax membrane. Ann. NY Acad. Sci. 341:534-551.
26. Miller, C., and M.M. White. 1984. Dimeric structure of single chloride channels from Torpedo electroplax. Proc. Natl. Acad. Sci. USA. 81:2772-2775.
27. Mindell, J.A., M. Maduke, C. Miller, and N. Grigorieff. 2001. Projection structure of a ClC-type chloride channel at 6.5 Å resolution. Nature. 409:219-223.
28. Picollo, A., and M. Pusch. 2005. Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5. Nature. 436:420-423.
29. Pusch, M., and T.J. Jentsch. 2005. Unique structure and function of chloride transporting CLC proteins. IEEE Trans. Nanobioscience. 4:49-57.
30. Pusch, M., K. Steinmeyer, and T.J. Jentsch. 1994. Low single channel conductance of the major skeletal muscle chloride channel, ClC-1. Biophys. J. 66:149-152.
31. Pusch, M., U. Ludewig, and T.J. Jentsch. 1997. Temperature dependence of fast and slow gating relaxations of ClC-0 chloride channels. J. Gen. Physiol. 109:105-116.
32. Pusch, M., A. Liantonio, L. Bertorello, A. Accardi, A. De Luca, S. Pierno, V. Tortorella, and D.C. Camerino. 2000. Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives. Mol. Pharmacol. 58:498-507.
33. Rychkov, G.Y., M. Pusch, D.S. Astill, M.L. Roberts, T.J. Jentsch, and A.H. Bretag. 1996. Concentration and pH dependence of skeletal muscle chloride channel ClC- 1. J. Physiol. 497:423-435.
34. Scheel, O., A.A. Zdebik, S. Lourdel, and T.J. Jentsch. 2005. Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins. Nature. 436:424-427.
35. Traverso, S., L. Elia, and M. Pusch. 2003. Gating competence of constitutively open CLC-0 mutants revealed by the interaction with a small organic inhibitor. J. Gen. Physiol. 122:295-306.
36. Uchida, S., and S. Sasaki. 2005. Function of chloride channels in the kidney. Annu. Rev. Physiol. 67:759-778.
37. White, M.M., and C. Miller. 1979. A voltage-gated anion channel from the electric organ of Torpedo californica. J. Biol. Chem. 254:10161-10166.